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1. 发明申请

WO2006088989A1 MEDICAL DEVICES 审中-公开
标题翻译：医疗设备
公开(公告)号：WO2006088989A1
公开(公告)日：2006-08-24
申请号：PCT/US2006/005400
申请日：2006-02-16
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HORN, Daniel J. , CHEN, John Jianhua , WEBER, Jan , HOLMAN, Thomas J.
发明人： HORN, Daniel J. , CHEN, John Jianhua , WEBER, Jan , HOLMAN, Thomas J.
IPC分类号： A61F2/06 , A61M25/10
CPC分类号： A61M25/104 , A61F2002/9583 , A61F2250/0068 , A61L29/126 , A61M2025/1086
摘要： Medical devices and related methods are disclosed. In some embodiments, a medical device includes an inflatable balloon (200) having a wall with an interior surface and an exterior surface defining a wall thickness therebetween, and in the exterior surface a void (220) in which the wall thickness is reduced, and a nanomaterial (230) disposed within the void.
摘要翻译：公开了医疗器械及相关方法。在一些实施例中，医疗装置包括可膨胀气囊（200），其具有壁，所述壁具有内表面和限定其间壁厚的外表面，并且在外表面中具有其中壁厚度减小的空隙（220），以及设置在空隙内的纳米材料（230）。

2. 发明申请

WO2009033082A2 MEDICAL DEVICES CONTAINING SILICATE AND CARBON PARTICLES 审中-公开
标题翻译：含有硅酸盐和碳颗粒的医疗器械
公开(公告)号：WO2009033082A2
公开(公告)日：2009-03-12
申请号：PCT/US2008/075475
申请日：2008-09-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, John Jianhua , HORN, Daniel, J. , ATANASOSKA, Liliana , WEBER, Jan
发明人： CHEN, John Jianhua , HORN, Daniel, J. , ATANASOSKA, Liliana , WEBER, Jan
IPC分类号： A61L29/02 , A61L29/16 , A61L31/02 , A61L31/16
CPC分类号： A61L31/026 , A61L29/02 , A61L29/103 , A61L29/126 , A61L29/16 , A61L31/02 , A61L31/024 , A61L31/084 , A61L31/126 , A61L31/16 , A61L2300/416
摘要： According to one aspect of the present invention, implantable and insertable medical devices are provided which contain one or more particle-containing regions that comprise silicate particles and carbon particles.
摘要翻译：根据本发明的一个方面，提供了可植入和可插入的医疗装置，其包含一个或多个包含硅酸盐颗粒和碳颗粒的含颗粒的区域。

3. 发明申请

WO2016054193A1 DUAL-LAYER BALLOON DESIGN AND METHOD OF MAKING THE SAME 审中-公开
标题翻译：双层气球设计及其制作方法
公开(公告)号：WO2016054193A1
公开(公告)日：2016-04-07
申请号：PCT/US2015/053201
申请日：2015-09-30
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： CHEN, John Jianhua , HORN, Daniel James , ROYER, Adam Joseph
IPC分类号： A61L29/06
CPC分类号： A61M25/10 , A61L29/06 , A61M25/1029 , A61M2025/1075 , B29C49/0021 , B29K2067/003 , C08L67/02
摘要： An expandable medical balloon, the expandable medical balloon comprising a first balloon wall, the first balloon wall comprising a first balloon layer of polyethylene terephthalate having a first intrinsic viscosity, the first layer is outer to a second layer of polyethylene terephthalate, the second balloon layer of polyethylene terephthalate having a second intrinsic viscosity, the second layer is an inner layer, wherein the intrinsic viscosity of the first balloon layer is higher than the intrinsic viscosity of the second balloon layer by about 0.05 dl/g or more.
摘要翻译：一种可膨胀医用气囊，该可扩张医用气囊包括一第一球囊壁，该第一球囊壁包括具有第一特性粘度的第一聚对苯二甲酸乙二醇酯层，该第一层位于第二层聚对苯二甲酸乙二醇酯外层，该第二球囊层的具有第二特性粘度的聚对苯二甲酸乙二醇酯，第二层是内层，其中第一球囊层的特性粘度高于第二球囊层的特性粘度约0.05dl / g或更大。

4. 发明申请

WO2015023880A1 MEDICAL GUIDEWIRE 审中-公开
标题翻译：医疗指南
公开(公告)号：WO2015023880A1
公开(公告)日：2015-02-19
申请号：PCT/US2014/051130
申请日：2014-08-14
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： HOU, Dongming , CHEN, John Jianhua , CHANG, Robert , INO, Takashi H. , SUTTON, Benjamin T.
IPC分类号： A61M25/09
CPC分类号： A61F2/2427 , A61M25/09 , A61M25/0905 , A61M2025/09008 , A61M2025/091 , A61M2025/09133 , A61M2025/0915 , A61M2025/09166 , A61M2025/09175 , A61M2025/09183 , A61M2210/125 , A61M2210/127
摘要： A guidewire system may include a guidewire having a relatively stiff proximal section and a relatively flexible distal section joined by a transition region, and a TAVI device slidably disposed on the guidewire. The guidewire may include an expandable element disposed about the transition region. The expandable element may be configured to expand from a collapsed configuration to an expanded configuration. The guidewire may include an expandable element disposed at the distal end. The distal section may be pre-configured to form more than one distal loop. A method of protecting an apex of a left ventricle during a TAVI procedure may include inserting a guidewire into the left ventricle, positioning a transition region adjacent the apex, expanding an expandable element such that the expandable element spans the apex, advancing a TAVI device distally over the guidewire to an aortic valve, and performing a TAVI procedure at the aortic valve.
摘要翻译：导丝系统可以包括具有相对刚性的近端部分和由过渡区域连接的相对柔性的远侧部分的导丝和可滑动地设置在导丝上的TAVI装置。引导线可以包括围绕过渡区域设置的可扩张元件。可扩展元件可以被配置为从折叠构型扩展到扩展构型。引导线可以包括设置在远端处的可扩张元件。远侧部分可以预先配置成形成多于一个的远端环。在TAVI过程中保护左心室顶点的方法可包括将导线插入左心室，将过渡区域定位在邻近顶点的位置，使可扩张元件膨胀使得可扩张元件跨越顶点，使TAVI器件向远端延伸在导丝上穿过主动脉瓣，并在主动脉瓣上执行TAVI程序。

5. 发明申请

WO2015002787A1 MEDICAL DEVICES FOR RENAL NERVE ABLATION 审中-公开
标题翻译：用于神经退行的医疗器械
公开(公告)号：WO2015002787A1
公开(公告)日：2015-01-08
申请号：PCT/US2014/044126
申请日：2014-06-25
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： HANSON, Cass A. , CAO, Hong , CHEN, John Jianhua , SUTERMEISTER, Derek C. , QUILLIN, Daniel T. , PEDERSON, JR., Gary J.
IPC分类号： A61B18/14 , A61B18/16 , A61B18/12 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00797 , A61B2018/124 , A61B2018/1467 , A61B2018/162 , A61B2018/165
摘要： Medical devices and methods for making and using the same are disclosed. An example medical device may include a medical device for renal nerve ablation. The medical device may include an elongate shaft having a distal region. An expandable member may be coupled to the distal region. A plurality of electrodes may be coupled to the expandable member and a single conductive member may be coupled to each electrode. Where one of the plurality of electrodes is active, the remaining electrodes may be inactive and act as ground or return electrodes. The electrode of the plurality of electrodes that is active may change over time.
摘要翻译：公开了用于制造和使用它们的医疗装置和方法。示例性医疗装置可以包括用于肾神经消融的医疗装置。医疗装置可以包括具有远侧区域的细长轴。可扩张构件可以联接到远端区域。多个电极可以耦合到可扩展构件，并且单个导电构件可以联接到每个电极。在多个电极中的一个是有源的情况下，剩余的电极可能是无效的并且用作接地或返回电极。多个电极中的有效电极可随时间而变化。

6. 发明公开

EP3016605A1 MEDICAL DEVICES FOR RENAL NERVE ABLATION 有权
标题翻译：用于肾神经切除的医疗设备
公开(公告)号：EP3016605A1
公开(公告)日：2016-05-11
申请号：EP14739334.2
申请日：2014-06-25
申请人： Boston Scientific Scimed, Inc.
发明人： HANSON, Cass A. , CAO, Hong , CHEN, John Jianhua , SUTERMEISTER, Derek C. , QUILLIN, Daniel T. , PEDERSON, JR., Gary J.
IPC分类号： A61B18/14 , A61B18/16 , A61B18/12 , A61B18/00
CPC分类号： A61B18/1492 , A61B2018/0022 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/00797 , A61B2018/124 , A61B2018/1467 , A61B2018/162 , A61B2018/165
摘要： Medical devices and methods for making and using the same are disclosed. An example medical device may include a medical device for renal nerve ablation. The medical device may include an elongate shaft having a distal region. An expandable member may be coupled to the distal region. A plurality of electrodes may be coupled to the expandable member and a single conductive member may be coupled to each electrode. Where one of the plurality of electrodes is active, the remaining electrodes may be inactive and act as ground or return electrodes. The electrode of the plurality of electrodes that is active may change over time.
摘要翻译：公开了医疗装置及其制造和使用方法。示例医疗装置可以包括用于肾神经消融的医疗装置。医疗装置可以包括具有远侧区域的细长轴。可扩张构件可以联接到远侧区域。多个电极可以联接到可扩张构件，并且单个导电构件可以联接到每个电极。在多个电极中的一个是有源的情况下，其余电极可以是不活动的并且充当接地或返回电极。活动的多个电极的电极可随时间变化。

7. 发明授权

EP3016605B1 MEDICAL DEVICES FOR RENAL NERVE ABLATION 有权
公开(公告)号：EP3016605B1
公开(公告)日：2019-06-05
申请号：EP14739334.2
申请日：2014-06-25
申请人： Boston Scientific Scimed, Inc.
发明人： HANSON, Cass A. , CAO, Hong , CHEN, John Jianhua , SUTERMEISTER, Derek C. , QUILLIN, Daniel T. , PEDERSON, JR., Gary J.
IPC分类号： A61B18/14 , A61B18/16 , A61B18/12 , A61B18/00

8. 发明公开

EP3200845A1 DUAL-LAYER BALLOON DESIGN AND METHOD OF MAKING THE SAME 有权
标题翻译：双层气球设计及其制造方法
公开(公告)号：EP3200845A1
公开(公告)日：2017-08-09
申请号：EP15778554.4
申请日：2015-09-30
申请人： Boston Scientific Scimed, Inc.
发明人： CHEN, John Jianhua , HORN, Daniel James , ROYER, Adam Joseph
IPC分类号： A61L29/06
CPC分类号： A61M25/10 , A61L29/06 , A61M25/1029 , A61M2025/1075 , B29C49/0021 , B29K2067/003 , C08L67/02
摘要： An expandable medical balloon, the expandable medical balloon comprising a first balloon wall, the first balloon wall comprising a first balloon layer of polyethylene terephthalate having a first intrinsic viscosity, the first layer is outer to a second layer of polyethylene terephthalate, the second balloon layer of polyethylene terephthalate having a second intrinsic viscosity, the second layer is an inner layer, wherein the intrinsic viscosity of the first balloon layer is higher than the intrinsic viscosity of the second balloon layer by about 0.05 dl/g or more.
摘要翻译：可扩张医用气球，所述可扩张医用气球包括第一球囊壁，所述第一球囊壁包括具有第一特性粘度的聚对苯二甲酸乙二醇酯的第一球囊层，所述第一层在聚对苯二甲酸乙二醇酯的第二层外部，所述第二球囊层具有第二特性粘度的聚对苯二甲酸乙二醇酯，所述第二层是内层，其中所述第一球囊层的特性粘度高于所述第二球囊层的特性粘度约0.05dl / g或更高。

9. 发明授权

EP3033135B1 MEDICAL GUIDEWIRE 失效
标题翻译：医疗指导
公开(公告)号：EP3033135B1
公开(公告)日：2017-05-24
申请号：EP14755553.6
申请日：2014-08-14
申请人： Boston Scientific Scimed, Inc.
发明人： HOU, Dongming , CHEN, John Jianhua , CHANG, Robert , INO, Takashi H. , SUTTON, Benjamin T.
IPC分类号： A61M25/09 , A61F2/24
CPC分类号： A61F2/2427 , A61M25/09 , A61M25/0905 , A61M2025/09008 , A61M2025/091 , A61M2025/09133 , A61M2025/0915 , A61M2025/09166 , A61M2025/09175 , A61M2025/09183 , A61M2210/125 , A61M2210/127
摘要： A guidewire system may include a guidewire having a relatively stiff proximal section and a relatively flexible distal section joined by a transition region, and a TAVI device slidably disposed on the guidewire. The guidewire may include an expandable element disposed about the transition region. The expandable element may be configured to expand from a collapsed configuration to an expanded configuration. The guidewire may include an expandable element disposed at the distal end. The distal section may be pre-configured to form more than one distal loop. A method of protecting an apex of a left ventricle during a TAVI procedure may include inserting a guidewire into the left ventricle, positioning a transition region adjacent the apex, expanding an expandable element such that the expandable element spans the apex, advancing a TAVI device distally over the guidewire to an aortic valve, and performing a TAVI procedure at the aortic valve.
摘要翻译：导丝系统可以包括具有相对刚性的近侧区段和由过渡区域连接的相对柔性的远侧区段的导丝以及可滑动地设置在导丝上的TAVI装置。导丝可以包括围绕过渡区布置的可扩张元件。可膨胀元件可以被构造成从折叠构型膨胀到膨胀构型。导丝可以包括设置在远端处的可扩张元件。远侧部分可以被预先构造成形成多于一个远侧环。在TAVI过程期间保护左心室的顶点的方法可以包括将导丝插入左心室中，将过渡区域定位在顶点附近，使可膨胀元件膨胀，使得可膨胀元件跨越顶点，向远侧推进TAVI装置通过导丝至主动脉瓣，并且在主动脉瓣处执行TAVI程序。

10. 发明公开

EP3033135A1 MEDICAL GUIDEWIRE 失效
标题翻译： MEDIZINISCHERFÜHRUNGSDRAHT
公开(公告)号：EP3033135A1
公开(公告)日：2016-06-22
申请号：EP14755553.6
申请日：2014-08-14
申请人： Boston Scientific Scimed, Inc.
发明人： HOU, Dongming , CHEN, John Jianhua , CHANG, Robert , INO, Takashi H. , SUTTON, Benjamin T.
IPC分类号： A61M25/09
CPC分类号： A61F2/2427 , A61M25/09 , A61M25/0905 , A61M2025/09008 , A61M2025/091 , A61M2025/09133 , A61M2025/0915 , A61M2025/09166 , A61M2025/09175 , A61M2025/09183 , A61M2210/125 , A61M2210/127
摘要： A guidewire system may include a guidewire having a relatively stiff proximal section and a relatively flexible distal section joined by a transition region, and a TAVI device slidably disposed on the guidewire. The guidewire may include an expandable element disposed about the transition region. The expandable element may be configured to expand from a collapsed configuration to an expanded configuration. The guidewire may include an expandable element disposed at the distal end. The distal section may be pre-configured to form more than one distal loop. A method of protecting an apex of a left ventricle during a TAVI procedure may include inserting a guidewire into the left ventricle, positioning a transition region adjacent the apex, expanding an expandable element such that the expandable element spans the apex, advancing a TAVI device distally over the guidewire to an aortic valve, and performing a TAVI procedure at the aortic valve.
摘要翻译：导丝系统可以包括具有相对刚性的近端部分和由过渡区域连接的相对柔性的远侧部分的导丝和可滑动地设置在导丝上的TAVI装置。引导线可以包括围绕过渡区域设置的可扩张元件。可扩展元件可以被配置为从折叠构型扩展到扩展构型。导丝可以包括设置在远端的可扩张元件。远端部分可以预先配置成形成多于一个远端环。在TAVI过程中保护左心室顶点的方法可包括将导线插入左心室，将过渡区域定位在邻近顶点的位置，使可扩张元件膨胀使得可扩张元件跨越顶点，使TAVI器件向远端延伸在导丝上穿过主动脉瓣，并在主动脉瓣上执行TAVI程序。

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