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1. 发明申请

US20220183836A1 REPLACEMENT HEART VALVE DELIVERY DEVICE 有权
公开(公告)号：US20220183836A1
公开(公告)日：2022-06-16
申请号：US17602965
申请日：2020-04-09
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Declan Loughnane , Tim O'Connor , Takashi H. Ino
IPC分类号： A61F2/24
摘要： A medical device system may include a delivery device including an outer sheath and an inner shaft having a coupler fixed to a distal end of the inner shaft; and a replacement heart valve implant releasably attached to the coupler. The replacement heart valve implant may include an expandable anchor member defining a central longitudinal axis; and a locking mechanism attached to the expandable anchor member, the locking mechanism being configured to engage with the coupler. The delivery device may include a collar configured to releasably secure the coupler to the locking mechanism. The collar may include a stop element configured to selectively prevent disengagement of the collar from the locking mechanism

2. 发明授权

US10939996B2 Replacement heart valve commissure assembly 有权
公开(公告)号：US10939996B2
公开(公告)日：2021-03-09
申请号：US15998833
申请日：2018-08-16
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Jasper Ellington Adamek-Bowers , Ali Salahieh , Takashi H. Ino , Andrew James Harlan Backus , Anh Thu Pham , Brian D. Brandt , Mimi Trinh Fitterer , Michael P. Calomeni , Jarad S. Waisblatt
IPC分类号： A61F2/24 , A61F2/95
摘要： A replacement heart valve commissure assembly may include a locking mechanism including a first locking portion spaced apart from a second locking portion in a delivery configuration and configured to engage with the second locking portion in a deployed configuration, wherein the first locking portion is longitudinally actuatable relative to the second locking portion between the delivery and deployed configurations. The commissure assembly may include a first valve leaflet and a second valve leaflet each secured to the first locking portion. A first sleeve portion of the first valve leaflet may be fixedly attached to a first fabric sleeve wrapped around a first leg of the first locking portion by a first filament, and a second sleeve portion of the second valve leaflet may be fixedly attached to a second fabric sleeve wrapped around a second leg of the first locking portion by a second filament.

3. 发明授权

US10258467B2 Medical guidewire 有权
公开(公告)号：US10258467B2
公开(公告)日：2019-04-16
申请号：US15389224
申请日：2016-12-22
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Dongming Hou , John Jianhua Chen , Robert Chang , Takashi H. Ino , Benjamin T. Sutton
IPC分类号： A61F2/24 , A61M25/09
摘要： A guidewire system may include a guidewire having a relatively stiff proximal section and a relatively flexible distal section joined by a transition region, and a TAVI device slidably disposed on the guidewire. The guidewire may include an expandable element disposed about the transition region. The expandable element may be configured to expand from a collapsed configuration to an expanded configuration. The guidewire may include an expandable element disposed at the distal end. The distal section may be pre-configured to form more than one distal loop. A method of protecting an apex of a left ventricle during a TAVI procedure may include inserting a guidewire into the left ventricle, positioning a transition region adjacent the apex, expanding an expandable element such that the expandable element spans the apex, advancing a TAVI device distally over the guidewire to an aortic valve, and performing a TAVI procedure at the aortic valve.

4. 发明授权

US10245136B2 Containment vessel with implant sheathing guide 有权
公开(公告)号：US10245136B2
公开(公告)日：2019-04-02
申请号：US15498807
申请日：2017-04-27
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Takashi H. Ino , Randy S. Gamarra , Michael P. Calomeni , Christopher W. Ledesma , Mimi Trinh Fitterer
IPC分类号： A61F2/24 , A61F2/00 , A61B17/34 , A61F2/95
摘要： A containment vessel for storing and rinsing a medical implant coupled to a delivery system having an outer sheath may include a hollow element having a wall, a proximal end, a distal end, and a lumen extending between the proximal end and the distal end, the lumen of the hollow element being configured and adapted to contain a medical implant in a partially-deployed configuration during storage and rinsing of the medical implant and a proximal end cap including a secondary proximal end cap removably secured to the proximal end cap and configured to reversibly seal the proximal end cap to the outer sheath, thereby establishing a closed fluid connection between the lumen of the hollow element and a lumen of the outer sheath. The proximal end cap may include a sheathing guide configured and adapted to direct the medical implant into the lumen of the outer sheath.

5. 发明申请

US20190038408A1 MEDICAL IMPLANT LOCKING MECHANISM 审中-公开
公开(公告)号：US20190038408A1
公开(公告)日：2019-02-07
申请号：US16052231
申请日：2018-08-01
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Michael P. Calomeni , Takashi H. Ino , Randy S. Gamarra , Floriza Q. Escalona
IPC分类号： A61F2/24
摘要： A medical device system may include a replacement heart valve implant including an expandable anchor member reversibly actuatable between a delivery configuration and a deployed configuration, wherein the replacement heart valve implant includes at least one locking mechanism configured to lock the expandable anchor member in the deployed configuration, and at least one actuator element configured to releasably engage the at least one locking mechanism and actuate the expandable anchor member between the delivery configuration and the deployed configuration. The at least one actuator element may include external threads on a distal portion of each actuator element and a ramp disposed proximal of the external threads.

6. 发明申请

US20180161064A1 INTRODUCER WITH EXPANDABLE CAPABILITIES 审中-公开
公开(公告)号：US20180161064A1
公开(公告)日：2018-06-14
申请号：US15837174
申请日：2017-12-11
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Mimi Trinh Fitterer , Takashi H. Ino , Floriza Q. Escalona , Michael P. Calomeni
IPC分类号： A61B17/34 , A61M25/06
摘要： An example introducer is disclosed. An example introducer includes an inner liner including a lumen, a proximal region, and at least one folded portion extending longitudinally along the proximal region. The introducer further includes an expandable support member. The support member includes a plurality of ribs extending along a length of the support member. The introducer further includes a sheath attached to at least a portion of the support member and the support member is designed to shift from a first position to an expanded position.

7. 发明申请

US20170325951A1 SHEATHING AID 审中-公开
公开(公告)号：US20170325951A1
公开(公告)日：2017-11-16
申请号：US15498758
申请日：2017-04-27
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Floriza Q. Escalona , Takashi H. Ino , Mimi Trinh Fitterer , Andrew J.H. Backus
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/243 , A61F2/2439 , A61F2/2442 , A61F2/2466 , A61F2/966 , A61F2002/9522 , A61F2002/9665 , A61F2250/0069
摘要： A medical device apparatus may include a medical implant including a braided anchor member configured to actuate between a delivery configuration and a deployed configuration operatively connected to a delivery system. The delivery system may include a handle, an outer sheath extending distally from the handle, and an inner catheter disposed within the outer sheath. A sheathing aid may connect the delivery system to the medical implant, the sheathing aid being configured to guide the medical implant into the outer sheath upon relative closing movement therebetween. The sheathing aid may include a plurality of arms extending from the inner catheter to a proximal end of the braided anchor member. At least one arm of the plurality of arms may comprise a core member having a width and a flexible member positioned about the core member.

8. 发明申请

US20170042676A1 EVERTING LEAFLET DELIVERY SYSTEM WITH PIVOTING 审中-公开
标题翻译：具有优惠的LEAFLET交付系统
公开(公告)号：US20170042676A1
公开(公告)日：2017-02-16
申请号：US15219572
申请日：2016-07-26
申请人： BOSTON SCIENTIFIC SCIMED INC.
发明人： Andrew J.H. Backus , Randy S. Gamarra , Takashi H. Ino , Crissly Valdez Crisostomo
IPC分类号： A61F2/24
摘要： A replacement heart valve may comprise a tubular anchor member actuatable between an elongated delivery configuration and an expanded deployed configuration, a buckle member fixedly attached to the anchor member, a post member axially translatable relative to the buckle member, an actuator member including a suture member forming a loop unreleasably attached to a distal end thereof, the actuator member being releasably connected to a proximal end of the post member by the loop, a release pin extending axially along the actuator member and through the loop in a first position, wherein axial translation of the release pin to a second position proximal the first position disconnects the actuator member from the post member, and a valve leaflet attached to the post member.
摘要翻译：替换心脏瓣膜可以包括可在细长递送构型和扩张展开构型之间致动的管状锚固构件，固定地附接到锚定构件的扣环构件，可相对于带扣构件轴向平移的柱构件，包括缝合构件的致动器构件形成不可释放地附接到其远端的环，致动器构件通过环可释放地连接到柱构件的近端;释放销，沿着致动器构件轴向延伸并且在第一位置通过环，其中轴向平移所述释放销到所述第一位置附近的第二位置将所述致动器构件与所述柱构件断开，以及附接到所述柱构件的阀传单。

9. 发明申请

US20210162171A1 FULLY COMPLIANT LARGE BORE EXPANDABLE SHEATH 有权
公开(公告)号：US20210162171A1
公开(公告)日：2021-06-03
申请号：US17160662
申请日：2021-01-28
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Mimi Trinh Fitterer , Takashi H. Ino , Randy S. Gamarra , Floriza Q. Escalona
IPC分类号： A61M25/00 , B29C65/00 , B29C65/48 , A61M25/01 , A61B17/3207 , A61M29/02 , A61M25/06 , B29L31/00
摘要： An expandable sheath may include an inelastic compliant membrane having a lumen therethrough, and a discontinuous outer member bonded to the membrane. The membrane may include one or more folds formed therein. At least a portion of the outer member may extend continuously around a circumference of the membrane in a first configuration. The outer member may be configured to separate to a second configuration when subjected to a radially outward force from within the membrane. The outer member may taper from a first diameter adjacent a proximal hub to a second smaller diameter at a distal end. A method of manufacturing an expandable sheath may include forming one or more folds in a compliant membrane, cutting a plurality of apertures through a wall of an outer covering; and laminating the outer covering onto the membrane, wherein the plurality of apertures is disposed over the one or more folds.

10. 发明授权

US10918829B2 Fully compliant large bore expandable sheath 有权
公开(公告)号：US10918829B2
公开(公告)日：2021-02-16
申请号：US15001682
申请日：2016-01-20
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： Mimi Trinh Fitterer , Takashi H. Ino , Randy S. Gamarra , Floriza Q. Escalona
IPC分类号： A61M25/00 , A61M25/01 , A61B17/3207 , A61M29/02 , B29C65/48 , B29C65/00 , A61M25/06 , B29L31/00
摘要： An expandable sheath may include an inelastic compliant membrane having a lumen therethrough, and a discontinuous outer member bonded to the membrane. The membrane may include one or more folds formed therein. At least a portion of the outer member may extend continuously around a circumference of the membrane in a first configuration. The outer member may be configured to separate to a second configuration when subjected to a radially outward force from within the membrane. The outer member may taper from a first diameter adjacent a proximal hub to a second smaller diameter at a distal end. A method of manufacturing an expandable sheath may include forming one or more folds in a compliant membrane, cutting a plurality of apertures through a wall of an outer covering; and laminating the outer covering onto the membrane, wherein the plurality of apertures is disposed over the one or more folds.

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