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1. 发明申请

WO2012135190A9 SYSTEM AND METHOD FOR ATLAS REGISTRATION 审中-公开
标题翻译：用于ATLAS注册的系统和方法
公开(公告)号：WO2012135190A9
公开(公告)日：2013-05-10
申请号：PCT/US2012030700
申请日：2012-03-27
申请人： BOSTON SCIENT NEUROMODULATION , CARLTON KEITH , BLUM DAVID ARTHUR , MOFFITT MICHAEL A , KOKONES SCOTT
发明人： CARLTON KEITH , BLUM DAVID ARTHUR , MOFFITT MICHAEL A , KOKONES SCOTT
IPC分类号： G06F19/00
CPC分类号： G06T7/0038 , A61B34/25 , A61N1/08 , A61N1/36128 , A61N1/37247 , F04C2270/041 , G06F3/04815 , G06F3/04845 , G06F19/321 , G06F19/3481 , G06K9/4642 , G06K9/6215 , G06K2009/4666 , G06T3/40 , G06T3/4038 , G06T7/0012 , G06T7/30 , G06T7/33 , G06T7/38 , G06T11/003 , G06T11/60 , G06T15/005 , G06T15/08 , G06T19/00 , G06T19/003 , G06T2200/04 , G06T2200/24 , G06T2207/10064 , G06T2207/10072 , G06T2207/10081 , G06T2207/10088 , G06T2207/10092 , G06T2207/30016 , G06T2219/028
摘要： A system and method for providing processable data associated with anatomical images may provide a user interface including a pivot and stem tool via which to align multiple images, a flashlight bar for viewing portions of an overlaid image, and/or user-movable markers for establishing a location of one or more anatomical landmarks with regions of one or more images.
摘要翻译：用于提供与解剖图像相关联的可处理数据的系统和方法可以提供包括用于对准多个图像的枢轴和杆工具的用户界面，用于观看覆盖图像的部分的手电筒和/或用于建立具有一个或多个图像的区域的一个或多个解剖学界标的位置。

2. 发明申请

WO2012135195A3 COMMUNICATION INTERFACE FOR THERAPEUTIC STIMULATION PROVIDING SYSTEMS 审中-公开
标题翻译：用于治疗性刺激提供系统的通信接口
公开(公告)号：WO2012135195A3
公开(公告)日：2013-06-27
申请号：PCT/US2012030705
申请日：2012-03-27
申请人： BOSTON SCIENT NEUROMODULATION , SPARKS TROY , CARLTON KEITH , KOKONES SCOTT , MOFFITT MICHAEL A
发明人： SPARKS TROY , CARLTON KEITH , KOKONES SCOTT , MOFFITT MICHAEL A
IPC分类号： G06F19/00
CPC分类号： G06T7/0038 , A61B34/25 , A61N1/08 , A61N1/36128 , A61N1/37247 , F04C2270/041 , G06F3/04815 , G06F3/04845 , G06F19/321 , G06F19/3481 , G06K9/4642 , G06K9/6215 , G06K2009/4666 , G06T3/40 , G06T3/4038 , G06T7/0012 , G06T7/30 , G06T7/33 , G06T7/38 , G06T11/003 , G06T11/60 , G06T15/005 , G06T15/08 , G06T19/00 , G06T19/003 , G06T2200/04 , G06T2200/24 , G06T2207/10064 , G06T2207/10072 , G06T2207/10081 , G06T2207/10088 , G06T2207/10092 , G06T2207/30016 , G06T2219/028
摘要： A system and method for communicating patient data for therapeutic stimulation purposes may provide a communication interface for exporting patient data, a communication interface for importing patient data, and a user interface for programming a patient device in response to communication of patient data.
摘要翻译：用于传达用于治疗刺激目的的患者数据的系统和方法可以提供用于导出患者数据的通信接口，用于导入患者数据的通信接口和用于响应于患者数据的通信来编程患者设备的用户界面。

3. 发明申请

WO2013023076A3 CONTROL AND/OR QUANTIFICATION OF TARGET STIMULATION VOLUME OVERLAP AND INTERFACE THEREFOR 审中-公开
标题翻译：目标刺激体积重叠及其接口的控制和/或量化
公开(公告)号：WO2013023076A3
公开(公告)日：2013-07-11
申请号：PCT/US2012050174
申请日：2012-08-09
申请人： BOSTON SCIENT NEUROMODULATION , BOKIL HEMANT SHARAD , PIERRE MARK , CARLTON KEITH , MOFFITT MICHAEL A , MUSTAKOS RICHARD , CHEN DEAN
发明人： BOKIL HEMANT SHARAD , PIERRE MARK , CARLTON KEITH , MOFFITT MICHAEL A , MUSTAKOS RICHARD , CHEN DEAN
IPC分类号： A61N1/372 , A61N1/05 , A61N1/08 , A61N1/36
CPC分类号： A61N1/37247 , A61N1/0534 , A61N1/0551 , A61N1/08 , A61N1/36 , A61N1/36182
摘要： A method and system include a processor that outputs a characterization of a correspondence between a volume of estimated tissue activation and a target and/or side effect stimulation volume, and/or that provides controls by which to modify thresholds and/or amounts according to which the volume of estimated activation is to correspond to the target volume.
摘要翻译：方法和系统包括处理器，其输出估计的组织激活的体积与靶和/或副作用刺激体积之间的对应关系的表征，和/或提供用于修改阈值和/或量的控制估计激活的音量与目标音量相对应。

4. 发明申请

WO2009114468A3 SYSTEMS, APPARATUSES, AND METHODS FOR DIFFERENTIATING BETWEEN MULTIPLE LEADS IMPLANTED WITHIN A PATIENT 审中-公开
标题翻译：用于在患者中植入的多个引线之间进行分化的系统，装置和方法
公开(公告)号：WO2009114468A3
公开(公告)日：2009-12-17
申请号：PCT/US2009036526
申请日：2009-03-09
申请人： BOSTON SCIENT NEUROMODULATION , CHINN KENNY KINYEN , MOFFITT MICHAEL A , MEADOWS PAUL M
发明人： CHINN KENNY KINYEN , MOFFITT MICHAEL A , MEADOWS PAUL M
IPC分类号： A61N1/05 , A61B17/34
CPC分类号： A61N1/05 , A61B2017/320056 , A61N1/372 , A61N1/3752
摘要： Systems, apparatuses, and methods for differentiating between multiple leads that are implanted within a patient include a stimulator configured to be implanted at an implant site within the patient and generate electrical stimulation current, a plurality of leads each comprising one or more electrodes configured to deliver the electrical stimulation current at a stimulation site within the patient, and a shuttle assembly having a plurality of receiving ports each configured to receive a proximal portion of one of the leads and guide the leads from the stimulation site to the implant site of the stimulator. The shuttle assembly is configured to enable a user to differentiate between each of the leads after the leads are guided to the implant site of the stimulator.
摘要翻译：用于区分植入患者体内的多个引线之间的系统，装置和方法包括：被配置为植入患者内的植入部位并产生电刺激电流的刺激器，多个引线，每个引线包括一个或多个电极，在患者内的刺激部位处的电刺激电流以及具有多个接收端口的梭组件，每个接收端口被配置为接收一个引线的近端部分并将引线从刺激部位引导到刺激器的植入部位。穿梭组件被配置成使得使用者能够在引线被引导到刺激器的植入部位之后区分每个引线。

5. 发明申请

WO2012166656A3 COLLECTION OF CLINICAL DATA FOR GRAPHICAL REPRESENTATION AND ANALYSIS 审中-公开
标题翻译：收集用于图形表示和分析的临床数据
公开(公告)号：WO2012166656A3
公开(公告)日：2013-04-11
申请号：PCT/US2012039709
申请日：2012-05-25
申请人： BOSTON SCIENT NEUROMODULATION , MOFFITT MICHAEL A , REINHOLD JOHN J
发明人： MOFFITT MICHAEL A , REINHOLD JOHN J
IPC分类号： A61N1/36 , A61N1/372
CPC分类号： A61N1/37247 , A61N1/3615 , A61N1/36185 , A61N1/37235 , A61N1/37241
摘要： An external programmer for use with a neurostimulator. Electrical stimulation energy is serially conveyed into tissue of the patient via different combinations of electrodes implanted within the patient, thereby creating one or more clinical effects for each of the different electrode combinations. An influence of each of the different electrode combinations on the clinical effect (s) is determined. A graphical indication of the one or more clinical effects is generated based on the determined electrode combination influences. A graphical representation of the electrodes is displayed. The graphical indication of the clinical effect (s) is displayed adjacent the graphical electrode representation, such that a user can view an extent to which each of the different electrode combinations influences the clinical effect (s).
摘要翻译：用于神经刺激器的外部程序员。电刺激能量通过植入患者体内的电极的不同组合被顺序地输送到患者的组织中，从而为每个不同的电极组合产生一个或多个临床效果。确定每个不同电极组合对临床效果的影响。基于确定的电极组合影响产生一种或多种临床效果的图形指示。显示电极的图形表示。临床效果的图形指示显示在图形电极表示附近，使得用户可以观察每个不同电极组合影响临床效果的程度。

6. 发明申请

WO2012024441A2 USER INTERFACE FOR SEGMENTED NEUROSTIMULATION LEADS 审中-公开
标题翻译：用于SEGMENTED NEUROSTIMULATION LEADS的用户界面
公开(公告)号：WO2012024441A2
公开(公告)日：2012-02-23
申请号：PCT/US2011048144
申请日：2011-08-17
申请人： BOSTON SCIENT NEUROMODULATION , MOFFITT MICHAEL A , KOTHANDARAMAN SRIDHAR , MAKOUS JAMES C
发明人： MOFFITT MICHAEL A , KOTHANDARAMAN SRIDHAR , MAKOUS JAMES C
IPC分类号： A61N1/08 , A61N1/05 , A61N1/36 , A61N1/372 , G06F19/00
CPC分类号： A61N1/37247 , A61N1/0534 , A61N1/36064 , A61N1/36067 , A61N1/36071 , A61N1/36082 , A61N1/36182 , A61N1/36185 , G06F19/3406 , G16H40/63
摘要： An external control device for use with a neurostimulation system having a plurality of electrodes capable of conveying an electrical stimulation field into tissue in which the electrodes are implanted is provided. The external control device comprises a user interface having one or more control elements, a processor configured for generating stimulation parameters designed to modify the electrical stimulation field relative to one or more neurostimulation lead carrying the electrodes. The external control device further comprises output circuitry configured for transmitting the stimulation parameters to the neurostimulation system.
摘要翻译：提供了一种与神经刺激系统一起使用的外部控制装置，其具有能够将电刺激场传送到其中植入电极的组织中的多个电极。外部控制装置包括具有一个或多个控制元件的用户界面，被配置为产生刺激参数的处理器，该刺激参数旨在相对于承载电极的一个或多个神经刺激引线来修改电刺激场。外部控制装置还包括被配置为将刺激参数传送到神经刺激系统的输出电路。

7. 发明申请

WO2012158562A2 MANAGEMENT OF STIMULATION SAFETY LIMITS IN A NEUROSTIMULATION SYSTEM 审中-公开
标题翻译：神经系统中刺激安全限制的管理
公开(公告)号：WO2012158562A2
公开(公告)日：2012-11-22
申请号：PCT/US2012037646
申请日：2012-05-11
申请人： BOSTON SCIENT NEUROMODULATION , MOFFITT MICHAEL A , KOTHANDARAMAN SRIDHAR , PETERSON DAVID K L
发明人： MOFFITT MICHAEL A , KOTHANDARAMAN SRIDHAR , PETERSON DAVID K L
IPC分类号： A61N1/36
CPC分类号： A61N1/36142 , A61N1/36185 , A61N1/37241
摘要： A neurostimulation system for management of stimulation safety limits. The system determines a tissue charge injection metric at each electrode, compares the metric to the hard stop charge limit, and prevents the neurostimulator from delivering stimulation energy to the tissue region in accordance based on the comparison. The hard stop limit may be user-programmable or may be automatically modified in response to detection of electrode characteristics. The system may quantitatively notify a user of a value of the injected charge injected into the tissue. The electrodes may be organized into different sets, in which case, the system may directly control tissue charge independently at each of the electrode sets. If current steering is provided, the system may displace the electrical stimulation energy along the tissue region in one direction, while preventing the charge injection value at each of the electrodes from meeting or exceeding the hard stop charge limit.
摘要翻译：用于管理刺激安全限值的神经刺激系统。系统确定每个电极处的组织电荷注入度量，将该度量与硬停止电荷限制进行比较，并且根据比较来防止神经刺激器将刺激能量递送至组织区域。硬停止极限可以是用户可编程的，或者可以响应于电极特性的检测而被自动修改。该系统可以定量地向使用者通知注入到组织中的注入电荷的值。电极可以组织成不同的组，在这种情况下，系统可以在每个电极组中独立地直接控制组织电荷。如果提供电流转向，则系统可以沿着一个方向沿着组织区域移位电刺激能量，同时防止每个电极处的电荷注入值达到或超过硬停止充电极限。

8. 发明申请

WO2011047202A3 SYSTEM AND METHOD FOR MODELING ELECTRODE MORPHOLOGIES AND ESTIMATING VOLUME OF ACTIVATION IN TISSUE 审中-公开
标题翻译：用于建模电极形态的系统和方法以及估计组织中的活化体积
公开(公告)号：WO2011047202A3
公开(公告)日：2011-08-11
申请号：PCT/US2010052748
申请日：2010-10-14
申请人： BOSTON SCIENT NEUROMODULATION , MOFFITT MICHAEL A
发明人： MOFFITT MICHAEL A
IPC分类号： A61N1/372
CPC分类号： A61N1/37247 , A61N1/025 , A61N1/36185
摘要： A system comprises a user input device configured for receiving an electrode morphology having an electrode, memory storing at least one basis electrode model, and a processor configured for modeling the electrode by recalling the at least one basis electrode model from the memory, and using the recalled at least one basis electrode model multiple times to construct a model of the electrode. Another system comprises a processor configured for estimating at a plurality of spatial points a respective plurality of electrical field vectors resulting from a stimulation lead operating in accordance with the set of stimulation parameters, determining an amplitude of each electrical field vector and an angle between each electrical field vector and a vector aligned with an axis of the stimulation lead, and estimating a tissue of volume activation about the stimulation lead based on the determined amplitude and angle of each electrical field vector.
摘要翻译：一种系统包括用户输入装置，其被配置用于接收具有电极的电极形态，存储至少一个基准电极模型的存储器和经配置以通过从所述存储器调用所述至少一个基础电极模型来对所述电极进行建模的处理器，回忆至少一个基础电极模型多次以构建电极的模型。另一系统包括处理器，其被配置为在多个空间点处估计由根据该组刺激参数操作的刺激引线产生的相应多个电场矢量，确定每个电场矢量的幅度和每个电场矢量之间的角度场矢量和与刺激引线的轴对准的矢量，以及基于确定的每个电场矢量的幅度和角度来估计关于刺激引线的体积激活的组织。

9. 发明申请

WO2010065761A3 IMPLANTABLE NEUROSTIMULATORS HAVING REDUCED POCKET STIMULATION 审中-公开
标题翻译：可植入的神经刺激器具有减少的口袋刺激
公开(公告)号：WO2010065761A3
公开(公告)日：2010-08-12
申请号：PCT/US2009066621
申请日：2009-12-03
申请人： BOSTON SCIENT NEUROMODULATION , MOFFITT MICHAEL A , LEE DONGCHUL , BRADLEY KERRY
发明人： MOFFITT MICHAEL A , LEE DONGCHUL , BRADLEY KERRY
IPC分类号： A61N1/08 , A61N1/36 , A61N1/372 , A61N1/375
CPC分类号： A61N1/36175 , A61N1/08 , A61N1/36185 , A61N1/372 , A61N1/37205 , A61N1/3756
摘要： Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.
摘要翻译：提供了神经刺激器和使用神经刺激器的方法。将神经刺激器植入患者的组织袋内，并且从神经刺激器输送电能以刺激远离组织袋的目标组织位点。神经刺激器具有与一个或多个电极相关联的情况。电能以防止或至少减少由于电能返回到神经刺激器的壳体而可能发生的口袋刺激的方式返回到电极。

10. 发明申请

WO2014070290A3 SYSTEMS AND METHODS FOR VOLUME OF TISSUE ACTIVATED MODEL GENERATION AND USE 审中-公开
标题翻译：用于组织活动模型生成和使用的体系的系统和方法
公开(公告)号：WO2014070290A3
公开(公告)日：2014-06-26
申请号：PCT/US2013056112
申请日：2013-08-22
申请人： BOSTON SCIENT NEUROMODULATION
发明人： MOFFITT MICHAEL A , STEINKE KARL G
IPC分类号： G06F19/00 , A61N1/372
CPC分类号： G06F19/3437 , A61N1/36128 , A61N1/37247 , G06F19/345 , G06N3/084 , G06N3/086 , G06N5/02 , G06N99/005 , G16H50/20 , G16H50/50
摘要： A computer implemented system and method provides a volume of activation (VOA) estimation model that receives as input two or more electric field values of a same or different data type at respective two or more positions of a neural element and determines based on such input an activation status of the neural element. A computer implemented system and method provides a machine learning system that automatically generates a computationally inexpensive VOA estimation model based on output of a computationally expensive system.
摘要翻译：计算机实现的系统和方法提供了一种激活量（VOA）估计模型，其在神经元的相应两个或更多个位置处接收相同或不同数据类型的两个或多个电场值作为输入，并且基于这样的输入确定神经元激活状态。计算机实现的系统和方法提供了一种机器学习系统，其基于计算昂贵的系统的输出自动生成计算上廉价的VOA估计模型。

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