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1. 发明申请

WO2003066599A1 N-ALLYLOXYETHYL-1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE UND IHRE VERWENDUNG ALS ARZNEIMITTEL 审中-公开
标题翻译：的N-烯丙氧基-1,2,3,4,5,6-六氢-2,6-亚甲基-3- benzazocines及其作为药物
公开(公告)号：WO2003066599A1
公开(公告)日：2003-08-14
申请号：PCT/EP2003/000538
申请日：2003-01-21
申请人： BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG , CARTER, Adrian , ENSINGER, Helmut , GRAUERT, Matthias , STILLER, Detlef, Andre , WEISER, Thomas
发明人： CARTER, Adrian , ENSINGER, Helmut , GRAUERT, Matthias , STILLER, Detlef, Andre , WEISER, Thomas
IPC分类号： C07D221/26
CPC分类号： C07D401/14 , C07D221/26 , C07D405/14 , C07D413/14 , C07D417/14
摘要： Die vorliegende Erfindung betrifft 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole der allgemeinen Formel (1) worin die Reste R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 und R 9 die in der Beschreibung und in den Ansprüchen angegebenen Bedeutungen aufweisen können, Verfahren zu deren Herstellung sowie der Verwendung als Arzneimittel.
摘要翻译：本发明涉及以下通式的1,2,3,4,5,6-六氢-2,6-亚甲基-3- benzazocin -10-醇（1），其中基团R1，R2，R3，R4，R5， R6，R7可以具有在说明书和权利要求中的R8和R9给出的含义，它们的制备方法和作为药物的用途。

2. 发明授权

EP1154983B1 NEUE SUBSTITUIERTE 3-PHENOXY- UND 3-PHENYLALKYLOXY-2-PHENYL-PROPYLAMINE 有权
标题翻译：邻苯二甲酸3-苯氧基-2-苯基 - 丙酰胺
公开(公告)号：EP1154983B1
公开(公告)日：2004-04-28
申请号：EP00907556.5
申请日：2000-02-12
申请人： Boehringer Ingelheim Pharma GmbH & Co.KG
发明人： STRANSKY, Werner , GRAUERT, Matthias , CARTER, Adrian , WEISER, Thomas , BECHTEL, Wolf-Dietrich , ENSINGER, Helmut , LOTZ, Ralf, Richard, Hermann , PALLUK, Rainer , PSCHORN, Uwe
IPC分类号： C07C217/48 , C07D295/08 , C07D307/52 , C07D309/14 , C07D233/48 , A61K31/138 , A61K31/4453 , A61P9/06 , A61P25/28
CPC分类号： C07D295/088 , C07C217/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/66 , C07D233/48 , C07D307/52 , C07D309/14
摘要： The invention relates to novel substituted 3-phenoxy or 3-phenylalkyloxy-2-phenyl-propylamines of general formula (1), to methods for producing them and to their use as medicaments.
摘要翻译：本发明涉及通式（1）的新型取代的3-苯氧基或3-苯基烷氧基-2-苯基 - 丙胺，其制备方法和用作药物。

3. 发明授权

EP1015433B1 SUBSTITUIERTE 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCIN-10-OLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权
标题翻译：取代的1,2,3,4,5,6-六氢-2,6-亚甲基-3- benzazocine-10 OLE，制造方法相同，并且它们作为药物
公开(公告)号：EP1015433B1
公开(公告)日：2004-05-26
申请号：EP98950009.5
申请日：1998-09-09
申请人： Boehringer Ingelheim Pharma GmbH & Co.KG
发明人： GRAUERT, Matthias , CARTER, Adrian , BECHTEL, Wolf-Dietrich , WEISER, Thomas , PALLUK, Rainer , PSCHORN, Uwe
IPC分类号： C07D221/26 , A61K31/435 , A61K31/485
CPC分类号： C07D221/26
摘要： The invention relates to novel substituted 1,2,3,4,5,6-hexahydro-2.6-methano-3-benzazocine-10-oles of general formula (I), and to a method for the production and the use thereof as medicaments.

4. 发明授权

EP1235809B1 SUBSTITUIERTE 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权
标题翻译：取代1,2,3,4,5,6六氢-2,6-亚甲基-3- benzazocines及其作为药物
公开(公告)号：EP1235809B1
公开(公告)日：2003-11-12
申请号：EP00993781.4
申请日：2000-11-21
申请人： Boehringer Ingelheim Pharma GmbH & Co.KG
发明人： GRAUERT, Matthias , CARTER, Adrian , WEISER, Thomas , ENSINGER, Helmut , GAIDA, Wolfram , MIERAU, Joachim
IPC分类号： C07D221/26 , C07D221/22 , C07D407/06 , A61K31/445
CPC分类号： C07D405/06 , C07D221/26
摘要： The invention relates to substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines of the general formula (1), wherein the groups R?1, R2, R3, R3', R4, R5, R6¿, X and A are defined as per the description and claims, to a method for their production and to the use thereof as medicaments.

5. 发明授权

EP1100780B1 2,3,3a,4,9,9a-HEXAHYDRO-8-HYDROXY-1H-BENZ[F]INDOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权
标题翻译：甲基-2,3,3a，4,9,9a - 六氢-8-羟基-1H-苯并[F]吲哚，其制造方法相同，并且它们作为药物
公开(公告)号：EP1100780B1
公开(公告)日：2007-04-25
申请号：EP99936584.4
申请日：1999-07-22
申请人： Boehringer Ingelheim Pharma GmbH & Co.KG
发明人： GRAUERT, Matthias , HOENKE, Christoph , CARTER, Adrian , BECHTEL, Wolf-Dietrich , WEISER, Thomas , PALLUK, Rainer , PSCHORN, Uwe
IPC分类号： C07D209/60 , A61K31/40
CPC分类号： C07D209/60
摘要： The application relates to substituted 2,3,3a,4,9,9a hexahydro-8-hydroxy-1H-benz[f]indole derivatives, to a method for the production thereof, and to their use as medicaments. The inventive indole derivatives correspond to general formula (1).

6. 发明公开

EP1474398A1 N-ALLYLOXYETHYL-1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCINE UND IHRE VERWENDUNG ALS ARZNEIMITTEL 审中-公开
标题翻译：的N-烯丙氧基-1,2,3,4,5,6-六氢-2,6-亚甲基-3- benzazocines及其作为药物
公开(公告)号：EP1474398A1
公开(公告)日：2004-11-10
申请号：EP03737261.2
申请日：2003-01-21
申请人： Boehringer Ingelheim Pharma GmbH & Co.KG
发明人： CARTER, Adrian , ENSINGER, Helmut , GRAUERT, Matthias , STILLER, Detlef, Andre , WEISER, Thomas
IPC分类号： C07D221/26 , A61K31/439 , A61P9/00 , A61P25/00
CPC分类号： C07D401/14 , C07D221/26 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The invention relates to 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols of general formula (1) wherein the radicals R1, R2, R3, R4, R5, R6, R7, R8 and R9 can have the designations cited in the description and in the claims. The invention also relates to methods for the production thereof and to the use of the same as pharmaceuticals.

7. 发明申请

WO2003009011A2 OPTICAL FIBER HAVING HIGH TEMPERATURE INSENSITIVITY OVER A TEMPERATURE RANGE CENTERED ON A SELECTED TEMPERATURE AND METHOD OF MAKING SAME 审中-公开
标题翻译：在选择的温度下中心温度范围内具有高温敏感性的光纤及其制造方法
公开(公告)号：WO2003009011A2
公开(公告)日：2003-01-30
申请号：PCT/US2002/023118
申请日：2002-07-22
申请人： NUFERN , JACOBSON, Nils , CARTER, Adrian , TANKALA, Kanishka , FARRONI, Julia
发明人： CARTER, Adrian , TANKALA, Kanishka , FARRONI, Julia
IPC分类号： G02B
CPC分类号： G02B6/0219 , G02B6/02095
摘要： An optical fiber for use in making components of an optical communication system has cladding and core materials the constituents of which cause a component made from the fiber to have a rate of change with respect to temperature of a response to a signal which passes through zero at a temperature T m which is at or near a selected temperature, or falls within a selected temperature range; and the value of T m of a fiber can be controllably changed by changing the concentration of B 2 O 3 in the fiber core materiel.
摘要翻译：用于制造光通信系统的组件的光纤具有包层和芯材料，其成分使得由光纤制成的部件相对于对通过零的信号的响应的温度具有变化率处于或接近选定温度或落在选定温度范围内的温度Tm; 通过改变纤维芯材料中的B 2 O 3的浓度可以可控地改变纤维的Tm值。

8. 发明申请

WO2006017802A2 FIBER OPTIC ARTICLE 审中-公开
标题翻译：光纤物品
公开(公告)号：WO2006017802A2
公开(公告)日：2006-02-16
申请号：PCT/US2005/028032
申请日：2005-08-05
申请人： NUFERN , FARRONI, Julia, A. , MANYAM, Upendra, H. , JACOBSON, Nils , TANKALA, Kanishka , CARTER, Adrian
发明人： FARRONI, Julia, A. , MANYAM, Upendra, H. , JACOBSON, Nils , TANKALA, Kanishka , CARTER, Adrian
IPC分类号： G02B6/02
CPC分类号： G02B6/03661 , G02B6/02 , G02B6/02042 , G02B6/024 , G02B6/03638
摘要： An optical fiber comprising a core (120, 220, 320, 420, 520, 620, 720, 820) having at least one rare earth for providing light having a first wavelength responsive to the fiber being pumped by light having a second wavelength that is different than the first wavelength; an inner region (270, 370, 470, 570, 670, 770, 870) disposed about the core; a pump cladding (224, 324, 424, 524, 624, 724, 824) disposed about the inner region; a second cladding (128, 228, 328, 628, 728, 828) disposed about the pump cladding; wherein the index of refraction of the second cladding is less than that of the pump cladding, the index of refraction of the pump cladding is less than that of the inner region, and the index of refraction of the inner region is less than that of the core; and wherein the core comprises a V-number at the first wavelength of greater than 2.405 and wherein the core comprises a numerical aperture of less than 0.12.
摘要翻译：光纤，包括具有至少一个稀土的芯（120,220,320,420,520,620,720,820），用于提供响应于被泵浦的光纤的第一波长的光通过具有不同于第一波长的第二波长的光; 内部区域（270,370,470,570,670,770,870），所述内部区域围绕所述芯设置; 围绕所述内部区域布置的泵包壳（224,324,424,524,624,724,824）围绕泵包壳设置的第二包层（128,228,328,628,728,828）其中第二包层的折射率小于泵浦包层的折射率，泵浦包层的折射率小于内部区域的折射率，并且内部区域的折射率小于泵浦包层的折射率核心; 并且其中所述芯包含在大于2.405的所述第一波长处的V值，并且其中所述芯包括小于0.12的数值孔径。

9. 发明申请

WO2008116205A1 OPTICAL FIBER ARTICLE FOR HANDLING HIGHER POWER AND METHOD OF FABRICATING OR USING 审中-公开
标题翻译：用于处理高功率的光纤文章和制作或使用的方法
公开(公告)号：WO2008116205A1
公开(公告)日：2008-09-25
申请号：PCT/US2008/057950
申请日：2008-03-21
申请人： NUFERN , GUERTIN, Douglas , JACOBSON, Nils , TANKALA, Kanishka , CARTER, Adrian
发明人： GUERTIN, Douglas , JACOBSON, Nils , TANKALA, Kanishka , CARTER, Adrian
IPC分类号： G02B6/02
CPC分类号： C03B37/01222 , C03B37/01228 , C03B37/01231 , C03B37/02763 , C03B2203/18 , C03B2203/20 , C03B2203/32 , C03B2203/34 , C03B2205/06 , C03B2205/07 , G02B6/02042 , H01S3/06704 , H01S3/06708
摘要： An optical fiber preform, and method for fabricating, having a first core, a second core spaced from the first core and first and second regions, the first region having an outer perimeter having a first substantially straight length and the second region having an outer perimeter having a second substantially straight length facing the first straight length. One of the regions can comprise the first core and the other comprises the second core. The preform can be drawn with rotation to provide a fiber wherein a first core of the fiber is multimode at a selected wavelength of operation and a second core of the fiber is spaced from and winds around the first core and has a selected longitudinal pitch. The second core of the fiber can couple to a higher order mode of the first core and increase the attenuation thereof.
摘要翻译：一种光纤预制件及其制造方法，具有第一芯体，与第一芯体以及第一和第二区域隔开的第二芯体，第一区域具有第一基本上直的长度的外周边，第二区域具有外周边具有面向第一直线长度的第二基本上直的长度。其中一个区域可以包括第一核心，另一个包括第二核心。预成型件可以旋转拉伸以提供纤维，其中纤维的第一纤芯在所选波长的操作下是多模的，并且纤维的第二纤芯与第一纤芯间隔开并卷绕第一纤芯并具有选定的纵向间距。光纤的第二个核心可以耦合到第一个核心的高阶模式并增加其衰减。

10. 发明申请

WO2003009011A3 OPTICAL FIBER GRATING HAVING HIGH TEMPERATURE INSENSITIVITY 审中-公开
公开(公告)号：WO2003009011A3
公开(公告)日：2003-01-30
申请号：PCT/US2002/023118
申请日：2002-07-22
申请人： NUFERN , JACOBSON, Nils , CARTER, Adrian , TANKALA, Kanishka , FARRONI, Julia
发明人： CARTER, Adrian , TANKALA, Kanishka , FARRONI, Julia
IPC分类号： G02B6/34
摘要： An optical fiber (10) for use in making components of an optical communication system has cladding (14) and core (12) materials the constituents of which cause a component made from the fiber to have a rate of change with respect to temperature of a response to a signal which passes through zero at a temperature Tm which is at or near a selected temperature, or falls within a selected temperature range; and the value of Tm of a fiber can be controllably changed by changing the concentration of B2O3 in the fiber core material.

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