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    • 5. 发明申请
    • METHOD AND APPARATUS FOR CELL SORTING
    • 细胞分离的方法和装置
    • WO2005037982A2
    • 2005-04-28
    • PCT/US2004/033600
    • 2004-10-12
    • BACH, David, T.ANJANAPPA, Muniswamappa
    • BACH, David, T.ANJANAPPA, Muniswamappa
    • C12M
    • G01N15/1459G01N15/1456G01N2015/1006G01N2015/149G01N2035/0462Y10T436/25375Y10T436/2575
    • A cell sorter system that includes a precision pump that causes fluid containing cells to enter an inlet port where the fluid is exposed to source light of one or more wavelengths and where cells scatter light or produce fluorescence by known means, and the scattered light and/or fluorescence is used to detect the presence and position of desired cells. The fluid is passed into a select gate that can be magnetostrictive where it is cause to exit one of a plurality of ports, at least one of these ports receiving the desired cells. A controller controls the precision pump, the detection system, and the select gate so that cells are selected from the fluid. An optional vacuum system can be used to pull fluid or cells out of the selected exit port.
    • 一种细胞分选器系统,其包括精密泵,其使得含有细胞的流体进入入口端口,在该入口端口中流体暴露于一个或多个波长的源光,并且其中细胞通过已知的方式散射光或产生荧光,并且散射光和/ 或荧光用于检测所需细胞的存在和位置。 流体被传送到可以是磁致伸缩的选择门,在那里它导致离开多个端口中的一个端口,这些端口中的至少一个接收所需的单元。 控制器控制精密泵,检测系统和选择门,以便从流体中选择细胞。 可选的真空系统可用于将流体或细胞从选定的出口吸出。