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    • 4. 发明申请
    • IMPLANTABLE MEDICAL DEVICE FOR STIMULATING A HUMAN OR ANIMAL HEART
    • WO2021156012A1
    • 2021-08-12
    • PCT/EP2021/050286
    • 2021-01-08
    • BIOTRONIK SE & CO. KG
    • MIDGETT, Madeline AnneHUEGERICH, BurkhardWHITTINGTON, R. Hollis
    • A61N1/37
    • The invention relates to an implantable medical device for stimulating a human or animal heart, comprising a control unit, a memory unit, a stimulation unit for stimulating a cardiac region of a human or animal heart, and a detection unit for detecting an electrical signal of the same heart. The memory unit comprises a computer-readable program that causes the control unit to perform the following steps when executed on the control unit: a) detecting (110), with the detection unit, capture thresholds during an observation period, each capture threshold being detected in response to a sequence of pacing pulses delivered by the stimulation unit; b) storing the detected capture thresholds in the memory unit; c) determining (120) threshold-to-threshold differences between two consecutive capture thresholds in each case; and d) if a maximum determined threshold-to-threshold difference within the observation period is equal to or greater than a predetermined limit, adjusting (140; 170) a pacing output of the stimulation unit on the basis of the maximum capture threshold determined within a first time period, the first time period being equal to or shorter than the observation period; or if the maximum determined threshold-to-threshold difference within the observation period is smaller than the predetermined limit, adjusting (150; 170) the pacing output of the stimulation unit on the basis of the maximum capture threshold determined within a second time period, the second time period being shorter than the first time period.
    • 5. 发明申请
    • INTRA-BODY NETWORK SYSTEM
    • WO2022233633A1
    • 2022-11-10
    • PCT/EP2022/060956
    • 2022-04-26
    • BIOTRONIK SE & CO. KG
    • HUEGERICH, BurkhardKIBLER, Andrew B.QU, MinHOMAYOUN, Habib
    • A61N1/372A61N1/375A61N1/39
    • An intra-body network system, comprises a first implantable medical device (1) comprising a first communication circuitry (13) and a second implantable medical device (2) comprising a second communication circuitry (23). The first communication circuitry (13) and the second communication circuitry (23) are configured to establish, in an implanted state of the first implantable medical device (1) and the second implantable medical device (2), a communication for transmitting a communication signal from at least one of the first implantable medical device (1) to the second implantable medical device (2) and from the second implantable medical device (2) to the first implantable medical device (1). At least one of the first implantable medical device (1) and the second implantable medical device (2) comprises an antenna arrangement (15) configured to at least one of transmit and receive a communication signal in a first configuration state using a first directive radiation characteristic, in a second configuration state using a second directive radiation characteristic different from the first directive radiation characteristic and a third configuration state using a third directive radiation characteristic different from the first directive radiation characteristic and the second directive radiation characteristic.
    • 9. 发明公开
    • IMPLANTABLE MEDICAL DEVICE FOR STIMULATING A HUMAN OR ANIMAL HEART
    • EP3858429A1
    • 2021-08-04
    • EP20158056.0
    • 2020-02-18
    • BIOTRONIK SE & Co. KG
    • MIDGETT, Madeline AnneHUEGERICH, BurkhardWHITTINGTON, R. Hollis
    • A61N1/37
    • The invention relates to an implantable medical device for stimulating a human or animal heart, comprising a control unit, a memory unit, a stimulation unit for stimulating a cardiac region of a human or animal heart, and a detection unit for detecting an electrical signal of the same heart. The memory unit comprises a computer-readable program that causes the control unit to perform the following steps when executed on the control unit: a) detecting (110), with the detection unit, capture thresholds during an observation period, each capture threshold being detected in response to a sequence of pacing pulses delivered by the stimulation unit; b) storing the detected capture thresholds in the memory unit; c) determining (120) threshold-to-threshold differences between two consecutive capture thresholds in each case; and d) if a maximum determined threshold-to-threshold difference within the observation period is equal to or greater than a predetermined limit, adjusting (140; 170) a pacing output of the stimulation unit on the basis of the maximum capture threshold determined within a first time period, the first time period being equal to or shorter than the observation period; or if the maximum determined threshold-to-threshold difference within the observation period is smaller than the predetermined limit, adjusting (150; 170) the pacing output of the stimulation unit on the basis of the maximum capture threshold determined within a second time period, the second time period being shorter than the first time period.