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1. 发明申请

WO2009058578A1 VERTEBRAL BODY REPLACEMENT DEVICE AND METHOD FOR USE TO MAINTAIN A SPACE BETWEEN TWO VERTEBRAL BODIES WITHIN A SPINE 审中-公开
标题翻译： VERTEBRAL身体替代装置和用于维持脊椎内的两个VERTEBRAL身体之间的空间的方法
公开(公告)号：WO2009058578A1
公开(公告)日：2009-05-07
申请号：PCT/US2008/080143
申请日：2008-10-16
申请人： BIOSPINE, LLC , REFAI, Daniel , FARRIS, Jeffrey A.
发明人： REFAI, Daniel , FARRIS, Jeffrey A.
IPC分类号： A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61F2/44 , A61F2/30734 , A61F2/30744 , A61F2/4637 , A61F2002/2835 , A61F2002/30235 , A61F2002/3024 , A61F2002/30364 , A61F2002/30367 , A61F2002/30405 , A61F2002/30433 , A61F2002/30492 , A61F2002/30525 , A61F2002/3054 , A61F2002/3055 , A61F2002/30601 , A61F2002/30616 , A61F2002/30772 , A61F2002/30818 , A61F2002/4638 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2230/0069
摘要： The vertebral body replacement device (10) includes a body member (30) and a central rod member (40) that has two threaded portions (41, 42) and is configured to be operatively associated with the body member. The device also includes a first end member and a second end member (20) with the end members being configured to threadingly engage the threaded portions of the central rod member. The body member and the two end members are further constructed to inhibit rotational movement of the two end members when the device is positioned within a space within a spine as the two end members will engage the adjacent respective vertebral bodies following rotational actuation of the central rod member causing the end members to move in an axial direction relative to the body member, thereby allowing the two end members to apply a force to the two vertebral bodies. A surgical method using the device is also disclosed.
摘要翻译：椎体置换装置（10）包括主体构件（30）和具有两个螺纹部分（41,42）的中心杆构件（40），并且构造成与主体构件可操作地相关联。该装置还包括第一端构件和第二端构件（20），其中端构件构造成与中心杆构件的螺纹部分螺纹接合。主体构件和两个端部构件进一步构造成当装置定位在脊柱内的空间内时两个端部构件将随着中心杆的旋转致动而与相邻的相应椎体接合，从而阻止两个端构件的旋转运动使所述端部构件相对于所述本体构件在轴向上移动，从而允许所述两个端部构件向所述两个椎体施加力。还公开了使用该装置的手术方法。

2. 发明申请

WO2009058576A1 FOOTPLATE MEMBER AND A METHOD FOR USE IN A VERTEBRAL BODY REPLACEMENT DEVICE 审中-公开
标题翻译： FOOTPLATE会员和用于VERTEBRAL身体替代装置的方法
公开(公告)号：WO2009058576A1
公开(公告)日：2009-05-07
申请号：PCT/US2008/080127
申请日：2008-10-16
申请人： BIOSPINE, LLC , REFAI, Daniel , FARRIS, Jeffrey A.
发明人： REFAI, Daniel , FARRIS, Jeffrey A.
IPC分类号： A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61F2/30734 , A61F2/30744 , A61F2/44 , A61F2/4637 , A61F2002/2835 , A61F2002/30235 , A61F2002/3024 , A61F2002/30364 , A61F2002/30367 , A61F2002/30405 , A61F2002/30433 , A61F2002/30492 , A61F2002/30525 , A61F2002/3054 , A61F2002/3055 , A61F2002/30601 , A61F2002/30616 , A61F2002/30772 , A61F2002/30818 , A61F2002/4638 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2230/0069
摘要： The footplate member (80) includes an end surface (82), a sidewall (83) that is attached to the end surface, and an orientation mechanism (93) that is designed to align the footplate member in a certain position relative to at least one of the two end members (90) of the vertebral body replacement device. The orientation mechanism includes a plurality of tabs (91) located on an end wall of each end member and corresponding slots (88) located along the edge of the sidewall, with the tabs and slots being sized and positioned to mate. The footplate member also includes a locking mechanism (85) designed to couple the footplate member to an end member prior to the implantation of the vertebral body replacement device within a space within a spinal column. A method for assembling a vertebral body replacement device and a method for using a footplate member in a vertebral body replacement device is also disclosed.
摘要翻译：脚踏板构件（80）包括端面（82），附接到端表面的侧壁（83）和定向机构（93），其被设计成将脚踏板构件相对于至少相对于一定位置椎体置换装置的两个端部构件（90）中的一个。定位机构包括位于每个端部构件的端壁上的多个突片（91）和沿着侧壁边缘定位的对应的狭槽（88），其中突出部和狭槽的尺寸和位置被配置为配合。脚板构件还包括锁定机构（85），其被设计成在将脊椎体置换装置植入脊柱内的空间之前将脚板构件联接到端构件。还公开了一种用于组装椎体置换装置的方法和在椎体置换装置中使用脚板构件的方法。

3. 发明申请

WO2010096259A1 A MULTI-FUNCTIONAL SURGICAL INSTRUMENT AND METHOD OF USE FOR INSERTING AN IMPLANT BETWEEN TWO BONES 审中-公开
标题翻译：一种多功能手术仪器及使用两种手术之间的植入物的方法
公开(公告)号：WO2010096259A1
公开(公告)日：2010-08-26
申请号：PCT/US2010/022805
申请日：2010-02-02
申请人： AESCULAP IMPLANT SYSTEMS, LLC , REFAI, Daniel , FARRIS, Jeffrey, A.
发明人： REFAI, Daniel , FARRIS, Jeffrey, A.
IPC分类号： A61F2/44 , A61F2/46
CPC分类号： A61F2/44 , A61F2/4611 , A61F2002/30598 , A61F2002/4623 , A61F2002/4627 , A61F2002/4629
摘要： The surgical instrument (10) includes a handle (100) and a housing (200) member that has a first end that is fixed to the handle and a second end that is configured to receive an engagement member (301). The surgical instrument also has an implant holding mechanism (300) that is operatively associated with the housing member and the handle. The surgical instrument further includes a length control mechanism that has a knob (320), a rod member (310) and a toothed member. The toothed member is fixed to one end of the rod member and the knob (320) is attached to the other end. The surgical instrument also has a locking mechanism that includes a knob and a rod member having a proximal end to which the knob is attached and a distal end that is configured to detachably couple to a locking device. A surgical method for using the surgical instrument and a bone spacing kit is also disclosed.
摘要翻译：外科器械（10）包括手柄（100）和壳体（200）构件，其具有固定到手柄的第一端和构造成容纳接合构件（301）的第二端。手术器械还具有与壳体构件和把手可操作地相关联的植入物保持机构（300）。手术器械还包括具有旋钮（320），杆构件（310）和齿形构件的长度控制机构。有齿构件固定在杆构件的一端并且把手（320）附接到另一端。手术器械还具有锁定机构，该锁定机构包括旋钮和杆构件，杆构件具有附接旋钮的近端，以及构造成可拆卸地联接到锁定装置的远端。还公开了用于使用外科器械和骨间隔试剂盒的手术方法。

4. 发明申请

WO2008017067A2 BLUNT DISSECTION AND TISSUE ELEVATION INSTRUMENT 审中-公开
标题翻译：剔除和组织提升仪器
公开(公告)号：WO2008017067A2
公开(公告)日：2008-02-07
申请号：PCT/US2007/075183
申请日：2007-08-03
申请人： BIOSPINE, LLC , REFAI, Daniel
发明人： REFAI, Daniel
IPC分类号： A61B17/00
CPC分类号： A61B17/29 , A61B17/28 , A61B2017/2808 , A61B2017/320044 , A61B2090/0817
摘要： A handheld medical instrument designed for efficient, atraumatic blunt tissue dissection and/or elevation during surgery. The instrument generally comprises an elongated shaft having a cottonoid or similar disposable dissection device at one or both ends. Attachment to the cottonoid may be direct or the shaft may include grasping constructs designed to grasp the cottonoid or to grasp a support structure which is attached to the dissection device. The devices may have reusable components or may be disposable.
摘要翻译：手持式医疗器械设计用于在手术过程中进行有效的无创伤性钝器组织剥离和/或抬高。该器械通常包括在一端或两端具有棉球或类似的一次性解剖装置的细长轴。与棉球的附着可以是直接的，或者杆身可以包括抓握结构，其被设计为抓住棉球或抓住附接到解剖装置的支撑结构。这些设备可能有可重复使用的组件，也可能是一次性的。

5. 发明授权

EP2693962B1 ARTICULATING ROD ASSEMBLY 有权转让
标题翻译：铰链杆组件
公开(公告)号：EP2693962B1
公开(公告)日：2017-08-30
申请号：EP12714190.1
申请日：2012-04-05
申请人： Refai, Daniel
发明人： REFAI, Daniel , HASKINS, Tyler
IPC分类号： A61B17/70
CPC分类号： A61B17/704 , A61B17/7019 , A61B17/7023 , A61B17/705 , A61B17/7055
摘要： An articulating assembly includes a first elongated element for attachment to a first anatomical region, and a second elongated element for attachment to a second anatomical region. In at least one embodiment, a coupling connects the first and second elongated elements. The coupling includes a moveable joint configured to allow polyaxial movement of the first elongated element with respect to the second elongated element. The assembly further includes a locking mechanism. The locking mechanism is operable in an unlocked condition to permit polyaxial movement of the first elongated element with respect to the second elongated element, and a locked condition to immobilize the movable joint and fix the position of the first elongated element with respect to the second elongated element.
摘要翻译：铰接组件包括用于附接到第一解剖区域的第一细长元件和用于附接到第二解剖区域的第二细长元件。在至少一个实施例中，联接件连接第一细长元件和第二细长元件。该联接件包括可移动接头，该可移动接头构造成允许第一细长元件相对于第二细长元件的多轴运动。该组件还包括锁定机构。锁定机构可在解锁状态下操作，以允许第一细长元件相对于第二细长元件的多轴向移动，以及锁定状态以固定可移动接头并将第一细长元件相对于第二细长元件的位置固定元件。

6. 发明申请

WO2012138852A1 ARTICULATING ROD ASSEMBLY 审中-公开
标题翻译：文献综述
公开(公告)号：WO2012138852A1
公开(公告)日：2012-10-11
申请号：PCT/US2012/032312
申请日：2012-04-05
申请人： AESCULAP IMPLANT SYSTEMS, LLC , REFAI, Daniel , HASKINS, Tyler
发明人： REFAI, Daniel , HASKINS, Tyler
IPC分类号： A61B17/70
CPC分类号： A61B17/704 , A61B17/7019 , A61B17/7023 , A61B17/705 , A61B17/7055
摘要： An articulating assembly includes a first elongated element for attachment to a first anatomical region, and a second elongated element for attachment to a second anatomical region. In at least one embodiment, a coupling connects the first and second elongated elements. The coupling includes a moveable joint configured to allow polyaxia l movement of the first elongated element with respect to the second elongated element. The assembly further includes a locking mechanism. The locking mechanism is operable in an unlocked condition to permit polyaxial movement of the first elongated element with respect to the second elongated element, and a locked condition to immobilize the movable joint and fix the position of the first elongated element with respect to the second elongated element.
摘要翻译：铰接组件包括用于附接到第一解剖区域的第一细长元件和用于附接到第二解剖区域的第二细长元件。在至少一个实施例中，联接器连接第一和第二细长元件。联接器包括可移动接头，其被配置为允许第一细长元件相对于第二细长元件的多角度l运动。组件还包括锁定机构。锁定机构可在解锁状态下操作以允许第一细长元件相对于第二细长元件多轴运动，以及锁定状态以固定可动接头并将第一细长元件相对于第二细长元件的位置固定元件。

7. 发明申请

WO2010045301A1 A SURGICAL INSTRUMENT AND METHOD OF USE FOR INSERTING AN IMPLANT BETWEEN TWO BONES 审中-公开
标题翻译：一种手术仪器和使用两个牙体之间的植入物的方法
公开(公告)号：WO2010045301A1
公开(公告)日：2010-04-22
申请号：PCT/US2009/060608
申请日：2009-10-14
申请人： AESCULAP IMPLANT SYSTEMS, LLC , REFAI, Daniel , EBERSOLE, Jeffrey , FARRIS, Jeffrey
发明人： REFAI, Daniel , EBERSOLE, Jeffrey , FARRIS, Jeffrey
IPC分类号： A61F2/46
CPC分类号： A61F2/4611 , A61F2/44 , A61F2002/30471 , A61F2002/30507 , A61F2002/30523 , A61F2002/3055 , A61F2002/30616 , A61F2002/4622 , A61F2002/4627 , A61F2002/4628 , A61F2002/4642 , A61F2220/0025 , A61F2220/0091
摘要： The surgical instrument includes a handle assembly and an elongate member (201) that has first and second ends with the first end being located adjacent to the handle assembly and the second end being moveably connected to an implant engagement assembly (204). The surgical instrument also has a length control mechanism that includes a gripping portion, a drive shaft and a gear assembly (302). The surgical instrument further has a locking mechanism that includes a gripping portion, a connecting rod (403) and a coupling end (402). The length control mechanism functions to adjust the overall length of an implant that is held by the implant engagement assembly before being implanted in vivo. The locking mechanism operates to secure the overall length of the implant following final length adjustment and implantation. A surgical method for using the surgical instrument, a method of fabrication and a spinal implant insertion kit is also disclosed.
摘要翻译：手术器械包括手柄组件和细长构件（201），其具有第一端和第二端，其第一端位于手柄组件附近，并且第二端可移动地连接到植入物接合组件（204）。外科器械还具有长度控制机构，其包括夹持部分，驱动轴和齿轮组件（302）。手术器械还具有锁定机构，其包括握持部分，连杆（403）和联接端（402）。长度控制机构用于在体内植入之前调整由植入物接合组件保持的植入物的总长度。锁定机构用于在最终长度调节和植入之后固定植入物的整个长度。还公开了一种用于使用外科手术器械的手术方法，制造方法和脊柱植入物插入套件。

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