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1. 发明申请

WO0218540A3 PYRIDINE DERIVATIVES USEFUL AS CD40:CD154 BINDING INTERRUPTOR COMPOUNDS AND USE THEREOF TO TREAT IMMUNOLOGICAL COMPLICATIONS 审中-公开
标题翻译：吡啶衍生物有用的CD40：CD154结合中间体化合物及其用于治疗免疫综合征
公开(公告)号：WO0218540A3
公开(公告)日：2003-12-24
申请号：PCT/US0127361
申请日：2001-08-31
申请人： BIOGEN INC , ZHENG ZHONGLI , CARTER MARY-BETH , LIAO YUSHENG , SUN LIHONG , KIRKOVSKY LEONID , MROSE SUSAN , HSU YEN-MING , DAVID THOMAS , SHIPPS GERALD W JR , JINDAL SATISH , LENZ GEORGE R , NASH HUW M
发明人： ZHENG ZHONGLI , CARTER MARY-BETH , LIAO YUSHENG , SUN LIHONG , KIRKOVSKY LEONID , MROSE SUSAN , HSU YEN-MING , THOMAS DAVID , SHIPPS GERALD W JR , JINDAL SATISH , LENZ GEORGE R , NASH HUW M
IPC分类号： F25B9/00 , A61K31/444 , A61P1/04 , A61P1/16 , A61P9/02 , A61P9/04 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/06 , A61P19/02 , A61P25/28 , A61P27/02 , A61P29/00 , A61P35/02 , A61P37/00 , A61P37/06 , A61P37/08 , C07C311/47 , C07D401/14 , F25B9/14
CPC分类号： A61K31/444 , C07C311/47 , C07D401/14 , F25B9/10 , F25B9/145 , F25B2309/1408 , F25B2309/1411 , F25B2309/1418 , F25B2309/1424 , F25B2309/14241
摘要： The present invention relates to novel CD40:CD154 binding interruptor compounds of the formula (I), and use of these compounds and pharmaceutical compositions comprising them, to treat conditions associated with inappropriate CD154 activation in a subject. Specifically, this invention provides compounds which are identified by screening a library of small molecules for those that are capable of specifically binding CD154 and interrupting CD40:CD154 interaction.
摘要翻译：本发明涉及式（I）的新型CD40：CD154结合阻断剂化合物，以及包含它们的这些化合物和药物组合物的用途，以治疗与受试者不适当的CD154活化相关的病症。具体地，本发明提供了通过筛选能够特异性结合CD154并中断CD40：CD154相互作用的那些的小分子文库来鉴定的化合物。

2. 发明公开

EP2872999A4 HETEROGENEOUS AND/OR HOSTED PHYSICAL LAYER MANAGEMENT SYSTEM 有权转让
标题翻译： VERWALTUNGSSYSTEMFÜR异构体UND / ODER GEHOSTETE PHYSIKALISCHE SCHICHTEN
公开(公告)号：EP2872999A4
公开(公告)日：2016-02-24
申请号：EP13815986
申请日：2013-07-11
申请人： TYCO ELECTRONICS LTD UK , ADC TELECOMMUNICATIONS INC , SMITH TREVOR D , PATEL KAMLESH G , MALONE GENE , DAVID THOMAS
发明人： SMITH TREVOR D , PATEL KAMLESH G , MALONE GENE , THOMAS DAVID
IPC分类号： G06F15/16 , H04L12/24
CPC分类号： H04L41/022 , H04L41/0853 , H04L41/12
摘要： One embodiment is directed to a heterogeneous physical layer management system comprising first devices, each comprising first physical layer information acquisition technology to obtain physical layer information about cabling attached to the first devices. The system further comprises second devices, each comprising second physical layer information acquisition technology to obtain physical layer information about cabling attached to the second devices, wherein the second physical layer information acquisition technology differs from the first physical layer information acquisition technology. The system further comprises a common management application communicatively coupled to the first devices and the second devices, wherein the common management application is configured to aggregate physical layer information from the first devices and the second devices. Another embodiment is directed to providing a physical layer management application as a service hosted by a third party. Other embodiments are disclosed.
摘要翻译：一个实施例涉及包括第一设备的异构物理层管理系统，每个设备包括第一物理层信息获取技术，以获得关于连接到第一设备的布线的物理层信息。该系统还包括第二设备，每个设备包括第二物理层信息获取技术，以获得关于连接到第二设备的布线的物理层信息，其中第二物理层信息获取技术与第一物理层信息获取技术不同。该系统还包括通信地耦合到第一设备和第二设备的公共管理应用，其中公共管理应用被配置为聚集来自第一设备和第二设备的物理层信息。另一个实施例旨在提供作为由第三方托管的服务的物理层管理应用。公开了其它实施例。

3. 发明专利

GB2506353A Pressure sensor to assist in the management of a surgical stoma 未知
公开(公告)号：GB2506353A
公开(公告)日：2014-04-02
申请号：GB201217146
申请日：2012-09-26
申请人： HIGGINS ROGER , DAVID THOMAS , REEVES RICHARD
发明人： HIGGINS ROGER , THOMAS DAVID , REEVES RICHARD
IPC分类号： A61F5/44 , A61B5/20 , A61F5/445
摘要： A surgical stoma management device including a pressure detector 3 arranged to detect excess pressure in a stoma waste container 2 and an alert means activatable by said excess pressure. The alert which is generated by the device will be beneficial in the detection of conditions which might be a precursor to leakage of waste product from an arrangement of stoma waste containers. The alert may be audible or visible and may be remote from the sensor. The pressure detector may mount onto a conduit forming the waste collection system, may or may not be in fluid communication with the waste, or may connect to an outlet port of a waste container.

4. 发明专利

CA2639836A1 SYSTEM FOR CHOREOGRAPHING THE EXECUTION OF A PROCEDURE 未知
公开(公告)号：CA2639836A1
公开(公告)日：2010-03-25
申请号：CA2639836
申请日：2008-09-25
申请人： DAVID THOMAS
发明人： THOMAS DAVID
IPC分类号： G06F19/00 , G06F17/30
摘要： The invention is a system for choreographing the execution of a procedure via a series of procedural steps. The system includes a relational database application running on a computer. The database includes a resource table listing a plurality of procedures as a plurality of procedure records, each procedure record listing the resources and attributes required to execute the listed procedure. The database also includes at least one environmental component table listing a plurality of environmental component values of which one value is selected and which may be performed as part of the procedure, the plurality of environmental component values being listed as a plurality of environmental component records, each environmental component record including the characteristics of the listed environmental component. The database further includes an activity table linked to the resource table and the environmental component table, the activity table configured to generate a unique identifier when a procedure and environmental component value are selected from the resource and environment tables, respectively. The database further includes a choreography table linked to the activity table, the choreography table listing a plurality of choreography records, each choreography record corresponding to a unique selection from the environment component table and the resource table, each said choreography record listing in sequence order the procedural steps required to perform the selected procedure with the selected environmental component value. Finally, the database includes a report generator configured to generate a report listing the selected procedure and environmental component value together with the resulting procedural steps.

5. 发明专利

GB2412459A Product life and due diligence management system for goods susceptible to temperature and or humidity 未知
公开(公告)号：GB2412459A
公开(公告)日：2005-09-28
申请号：GB0505715
申请日：2005-03-21
申请人： DAVID THOMAS
发明人： THOMAS DAVID
IPC分类号： G06F17/40 , G06Q10/00 , G06F17/60
摘要： A service shared by shippers and receivers to keep independent records of environmental conditions (temperature and / or humidity) in which products are transported and / or stored and to estimate the reduction in life expectancy when these are not ideal. Digital signatures being automatically added to the data protects the integrity of the parameters used and the information collected by the logging device. The service uses the latest information provided by shippers and receivers in selling the parameters used by the logging device and calculating the estimated loss of life expectancy (including monetary valuation). The shipper is automatically advised by e-mail, with an optional attachment of a copy of the recordings, that the logging device has been downloaded. Shippers and receivers can add additional information, e.g. times when the logging device was not with the product, to improve the accuracy of the estimated loss.

6. 发明专利

GB2410904A Golf organiser kit 未知
公开(公告)号：GB2410904A
公开(公告)日：2005-08-17
申请号：GB0403213
申请日：2004-02-13
申请人： DAVID THOMAS
发明人： THOMAS DAVID
IPC分类号： A63B57/00 , A63B71/06 , B43K23/00 , B43K29/00
摘要： A golf organiser kit 10 for arranging and conducting a golf competition for a plurality of players. The kit comprises an organiser's check list including instructions for preparing and conducting the event. Further provided is a player itinerary to arrange and/or display details of the event such as the course and order of play to be followed (all generally indicated 19) and a writing implement 21. Also provided is at least one target marker 14 adapted to be inserted into the ground where desired which may be written on by the writing implement, and at least one tee reminder card that can be placed beside any chosen tee to indicate a particular objective to be carried out on that hole. The pack also includes a result recording sheet 20, a results announcement sheet, a handicap allowance chart and at least one prize certificate to be awarded to a player.

7. 发明专利

GB191419760A Improvements in, or connected with, Dredging, Excavating and Quarrying Apparatus. 未知
公开(公告)号：GB191419760A
公开(公告)日：1915-08-26
申请号：GB191419760D
申请日：1914-09-14
申请人： DAVID THOMAS
发明人： THOMAS DAVID
IPC分类号： E02F3/08
摘要： 19,760. Thomas, D. Sept. 14. Endless - chain machines. - An endless travelling chain of buckets 4 for excavating, dredging, or quarrying is carried by an arm made in two parts 5, 8 pivoted together and supported by a pivot 6 and by tackle 18, which passes over the pulleys 19 on a frame or jib 17. The material is discharged through a hollow ring- post 10 which forms the connexion between the upper carriage 7 supporting the jib, and the lower carriage 11 running on wheels 15 and made saddle - shaped so as to pass over a truck &c. to receive the material. The upper carriage may turn on wheels about the post 10. The gear-wheel 31 for the chain of buckets, and the shaft 29 for the drums 20 to which the lifting-tackle is connected, are both driven from the main shaft by spur and worm gearing. Suitable clutches connect the drums 20 with their shaft.

8. 发明专利

GB2460093A A splash guard for a wudu unit 未知
公开(公告)号：GB2460093A
公开(公告)日：2009-11-18
申请号：GB0809004
申请日：2008-05-17
申请人： DAVID THOMAS
发明人： THOMAS DAVID
IPC分类号： A47K3/022 , E03C1/181
摘要： A splash guard 3 for a wudu unit, the splash guard 3 reduces splashing when the wudu is being used during the Islamic washing ritual. The splash guard 3 maybe permanently attached to the floor of the wudu during manufacture or detachably attached to the floor of the wudu via suction cups thereby allowing the user to use larger or smaller guards dependent upon their requirement. Preferably the splash guard is placed between the seat 6 and the flow of water 5 from the tap 7 of the wudu.

9. 发明专利

GB2423661A Identifying scene changes 未知
公开(公告)号：GB2423661A
公开(公告)日：2006-08-30
申请号：GB0504091
申请日：2005-02-28
申请人： DAVID THOMAS
发明人： THOMAS DAVID
IPC分类号： H04N7/18 , G06T5/00 , G06T7/00 , G06T7/20 , G08B13/194
摘要： A data processing apparatus for automatically identifying a change in an observed scene. The apparatus is configured to segment an image of the scene into a plurality of segments each comprising a plurality of image elements. A change in intensity of a segment relative to the intensity of that segment in a preceding image is identified, and is determined if the intensity in said segment exceeds its threshold value.

10. 发明专利

GB2379006B Waste (water) heat extraction-recovery 未知
公开(公告)号：GB2379006B
公开(公告)日：2005-11-30
申请号：GB0115642
申请日：2001-06-27
申请人： DAVID THOMAS , THOMAS PETER
发明人： THOMAS DAVID , THOMAS PETER
IPC分类号： F24D17/00 , F28D7/10 , F28D21/00 , F28F9/22 , F24H1/12

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