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    • 1. 发明申请
    • COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING CATECHINS OR GREEN TEA EXTRACTS
    • 儿茶素或提取物绿茶含化妆品和皮肤科制剂
    • WO03009825A3
    • 2003-04-17
    • PCT/EP0207424
    • 2002-07-04
    • BEIERSDORF AGDOERING THOMASSCHREINER VOLKERSIEFKEN WILFRIEDSAUERMANN GERHARDRODE TIMOCARSTENSEN STEFANIE
    • DOERING THOMASSCHREINER VOLKERSIEFKEN WILFRIEDSAUERMANN GERHARDRODE TIMOCARSTENSEN STEFANIE
    • A61K8/06A61K8/49A61K8/97A61Q5/00A61Q17/00A61Q19/00A61Q19/08A61K7/48
    • A61Q5/006A61K8/06A61K8/498A61K8/97A61K2800/75A61Q17/00A61Q19/00A61Q19/005A61Q19/007A61Q19/08
    • The invention relates to the use of topically applicable preparations containing a content of: a) a compound or a number of compounds from the group consisting of catechins or bile acid esters of catechins or aqueous or organic extracts from plants or plant parts having a content of catechins or bile acid esters of catechins, for example, from the leaves of the plant family Theaceae, particularly of the species Camellia sinensis (green tea) or typical constituents thereof such as, e.g. polyphenols or catechins, caffeine, vitamins, sugar, minerals, amino acids, lipids and their precursors and derivatives; b) optionally a compound or a number of compounds from the group of electrolytes; c) optionally a compound or a number of compounds from the group of polyols and urea and optionally; d) a compound or a number of compounds from the group of osmolytes, for the treatment and active prevention of dry skin, for reinforcing the barrier function of the skin, and for the treatment, care and prophylaxis of sensitive skin and/or for the treatment and prophylaxis of the symptoms associated with a negative change in the physiological homeostasis of healthy skin, particularly with deficient, sensitive or hypoactive skin conditions or deficient, sensitive or hypoactive conditions of cutaneous appendages, inflammatory skin conditions and atopic eczema, polymorphic photodermatosis, psoriasis, vitiligo, sensitive, itchy or irritated skin, changes in the normal lipid peroxidation, a change in the ceramide, lipid and energy metabolism of healthy skin, a change in the physiological transepidermal water loss, a reduction in skin hydration and decrease in the moisture content of the skin, a change in the natural moisturizing factor content, a reduction in cell-cell communication, deficiency symptoms of the intracellular DNA synthesis, DNA damages and reduction of endogenic DNA repair mechanisms, activation of metal proteinases and/or other proteinases or inhibition of the corresponding endogenic DNA repair mechanisms, deviations from the normal post-translational modifications of connective tissue constituents, changes in the normal hyaluronic acid content and glucose aminoglycan content of healthy skin, scale-formation of the hair, formation of dandruff on the scalp and aging of the skin.
    • 本发明是使用含局部施用的制剂的一个)从儿茶素或具有儿茶素或胆汁酸酯的含量的植物或植物部分的水和有机提取物的儿茶素或胆汁酯形成的基团的化合物或几种化合物 包括儿茶素类,如植物山茶科的叶子,特别是种茶树(绿茶)或它们的典型成分,如 多酚和儿茶素类,咖啡因,维生素,糖,矿物质,氨基酸,脂质,和它们的前体和衍生物,b)从所述组的电解质的任选的一种或多种化合物,c)任选地,一种或多种选自多元醇化合物 和尿素和任选的d)选自渗透剂用于治疗和积极防止皮肤干燥并加强皮肤的屏障功能,以及用于敏感性皮肤的治疗,护理和预防和/或用于症状的治疗和预防的化合物或几种化合物 健康的皮肤,尤其是不足的,皮肤附件的皮肤或缺陷,敏感或活动减退状态中的敏感或活动减退状态,炎性皮肤病症,和特应性湿疹,多形性日光疹,牛皮癣,白癜风,敏感,瘙痒0的生理平衡的负变化 受刺激的皮肤,在正常的脂质过氧化的变化,健康皮肤的神经酰胺,脂肪和能量代谢的变化,在生理经皮水分流失的变化,皮肤水分减少,并减少皮肤的水分含量,天然保湿因子含量的变化,减少了 细胞 - 细胞通信,细胞内的DNA合成,DNA损伤和减少的内源DNA修复机制,从结缔组织组分的正常翻译后修饰金属蛋白酶和/或其他蛋白酶或相应的内源性DNA修复机制的抑制,偏差的激活的缺陷 在健康的皮肤,头发头皮屑,头皮和皮肤老化的头皮屑的正常透明质酸和Glucosaminoglycangehalts变化。