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1. 发明申请

WO2008151239A2 POSITIVE DISPLACEMENT STOPPER FOR A PRE-FILLED SYRINGE 审中-公开
标题翻译：一个预先填充的SYRINGE的积极位移停止
公开(公告)号：WO2008151239A2
公开(公告)日：2008-12-11
申请号：PCT/US2008065783
申请日：2008-06-04
申请人： BECTON DICKINSON CO , SCHILLER ERIC , QUINN MICHAEL , TORRES JOHANNA , GUAN E , ECONOMOU ANTHONY , JU GANG
发明人： SCHILLER ERIC , QUINN MICHAEL , TORRES JOHANNA , GUAN E , ECONOMOU ANTHONY , JU GANG
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with said main body adjacent the closed front end. The core member includes a nose portion having a profile adapted to create a positive seal with an outlet opening of such syringe barrel.
摘要翻译：公开了一种用于与注射器筒内使用的柱塞杆连接的塞子。止动器包括限定开口后端和封闭前端的主体。敞开的后端适于容纳柱塞杆的前部前端附接部分。挡块还包括与所述主体一体地形成在与封闭前端相邻的芯部件上。芯构件包括鼻部，其具有适于产生具有这种注射器筒的出口的正密封的轮廓。

2. 发明申请

WO2008151241A3 STOPPER AND PLUNGER ROD FOR A PRE-FILLED SYRINGE 审中-公开
标题翻译：用于预先灌装的塞子和塞子
公开(公告)号：WO2008151241A3
公开(公告)日：2009-01-29
申请号：PCT/US2008065787
申请日：2008-06-04
申请人： BECTON DICKINSON CO , SCHILLER ERIC , QUINN MICHAEL , TORRES JOHANNA , GUAN E , ECONOMOU ANTHONY , JU GANG
发明人： SCHILLER ERIC , QUINN MICHAEL , TORRES JOHANNA , GUAN E , ECONOMOU ANTHONY , JU GANG
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A plunger rod. (14) adapted for attachment with a stopper (12) for use with a syringe barrel (16) is disclosed. The plunger rod includes an elongated member (124) having a front end (126) and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm (130) associated with' the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.
摘要翻译：柱塞杆。（14）适于与用于与注射器筒（16）一起使用的塞子（12）附接。柱塞杆包括具有前端（126）和后端的细长构件（124），柱塞杆沿着纵向轴线延伸。柱塞杆包括与细长构件的前端相关联的至少一个偏转臂（130）。在将柱塞杆插入塞子期间，偏转臂能够径向向内偏转，并且在插入之后向外偏转到止动件的内表面以将柱塞杆锁定在止动件内。

3. 发明申请

WO2011126764A2 STOPPERS USED IN PRE-FILLED SYRINGES 审中-公开
标题翻译：在预灌装中使用的停止剂
公开(公告)号：WO2011126764A2
公开(公告)日：2011-10-13
申请号：PCT/US2011029933
申请日：2011-03-25
申请人： BECTON DICKINSON CO , QUINN MICHAEL VINCENT , SCHILLER ERIC , JU GANG , GUAN E
发明人： QUINN MICHAEL VINCENT , SCHILLER ERIC , JU GANG , GUAN E
IPC分类号： A61M5/315
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： A stopper adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body defining an open rearward end and a closed front end. The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper also includes a core member integrally formed with the main body adjacent the closed front end. The core member includes a nose portion having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.
摘要翻译：公开了一种用于与注射器筒内使用的柱塞杆连接的塞子。止动器包括限定开口后端和封闭前端的主体。敞开的后端适于容纳柱塞杆的前部前端附接部分。挡块还包括与主体相邻的封闭前端一体地形成的芯构件。核心构件包括具有锥形末端的鼻部部分，其被配置用于进入注射器筒的出口开口。止动器的封闭前端具有构造成与注射器筒壁的内表面配合以防止回流并减小镜筒内的死空间的轮廓。

4. 发明专利

JP2013255837A Plunger rod for pre-filled syringe 有权
标题翻译：用于预先灌装的灌装筒
公开(公告)号：JP2013255837A
公开(公告)日：2013-12-26
申请号：JP2013189423
申请日：2013-09-12
申请人： Becton Dickinson & Co , ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company
发明人： SCHILLER ERIC , MICHAEL QUINN , TORRES JOHANNA , GUAN E , ECONOMOU ANTHONY , JU GANG
IPC分类号： A61M5/31 , A61M5/28
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： PROBLEM TO BE SOLVED: To meet the need in the art for a plunger rod design that uses a reduced amount of processing material, has a reduced molding cycle time, and has a high resistance to side loading.SOLUTION: A plunger rod 14, adapted for attachment with a stopper 12 for use with a syringe barrel 16 is disclosed. The plunger rod comprises an elongated body portion 234 having a front end 236, a back end 238, and a sidewall portion 239 extending along a longitudinal axis between the front end and the back end. The sidewall portion comprises a plurality of longitudinally extending lobes 240 defining an interior hollow portion 242. The plunger rod further comprises: an attachment member 244 that is secured to the front end and is adapted for attachment of the plunger rod to the stopper; and a cover member 246 that is secured to the back end of the elongated body portion, for covering the interior hollow portion and providing a thumb press area 248 for application of a force to the plunger rod during use.
摘要翻译：要解决的问题：为了满足使用减少量的加工材料的柱塞杆设计的本领域的需要，具有缩短的成型周期时间，并且具有高的侧向负载性。解决方案：适于用于与注射器筒16一起使用的止动件12的附接。柱塞杆包括细长主体部分234，其具有前端236，后端238以及沿着前端和后端之间的纵向轴线延伸的侧壁部分239。侧壁部分包括限定内部中空部分242的多个纵向延伸的凸起240.柱塞杆还包括：固定到前端并适于将柱塞杆附接到止动件的附接构件244; 以及固定到细长主体部分的后端的盖构件246，用于覆盖内部中空部分并提供用于在使用期间向柱塞杆施加力的拇指按压区域248。

5. 发明专利

JP2013128823A Positive displacement stopper for pre-filled syringe 有权
标题翻译：用于预灌装的积极位移停止器
公开(公告)号：JP2013128823A
公开(公告)日：2013-07-04
申请号：JP2013076220
申请日：2013-04-01
申请人： Becton Dickinson & Co , ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company
发明人： SCHILLER ERIC , MICHAEL QUINN , TORRES JOHANNA , GUAN E , ECONOMOU ANTHONY , JU GANG
IPC分类号： A61M5/315 , A61M5/28
CPC分类号： A61M5/31513 , A61M5/31511 , A61M5/31515 , A61M2005/31521 , A61M2005/31523
摘要： PROBLEM TO BE SOLVED: To effectively and consistently reduce and/or eliminate reflux of fluid back into a syringe upon this release of pressure on a plunger rod when positive displacement of fluids from the syringe (for example, into any inserted catheter) after a stopper has been bottomed in a syringe barrel and force is released from the plunger rod.SOLUTION: A stopper (12) adapted for attachment with a plunger rod (14) for use within a syringe barrel (16) is disclosed. The stopper includes a body (26) defining an open rearward end (28) and a closed front end (30). The open rearward end is adapted to receive a front forward end attachment portion (31) of the plunger rod. The stopper also includes a core member (32) integrally formed with the body adjacent to the closed front end. The core member includes a nose portion (34) having a profile adapted to create a positive seal with an outlet opening of the syringe barrel.
摘要翻译：要解决的问题：为了有效和一致地减少和/或消除在针筒上释放压力之后流体回流到注射器中，当塞子从注射器（例如，插入导管）中移出流体时已经被注入到注射器筒中并且力从柱塞杆释放。解决方案：适于与用于注射器筒（16）内的柱塞杆（14）连接的塞子（12）。止动器包括限定开口后端（28）和闭合前端（30）的本体（26）。敞开的后端适于容纳柱塞杆的前部前端附接部分（31）。挡块还包括与主体相邻的封闭前端一体形成的芯构件（32）。芯构件包括具有适于与注射器筒的出口开口形成正密封的轮廓的鼻部（34）。

6. 发明专利

ES2891364T3 Tapón y vástago de émbolo para una jeringa prellenada 未知
公开(公告)号：ES2891364T3
公开(公告)日：2022-01-27
申请号：ES19153206
申请日：2008-06-04
申请人： BECTON DICKINSON CO
发明人： SCHILLER ERIC , QUINN MICHAEL , TORRES JOHANNA , GUAN E , ECONOMOU ANTHONY , JU GANG
IPC分类号： A61M5/315
摘要： Un vástago de émbolo (14) adaptado para unión a un tapón (12) para usar con un cilindro de jeringa (16), comprendiendo dicho vástago de émbolo (14): (a) un miembro alargado (124) que tiene un extremo frontal (126) y un extremo posterior (128) y que se extiende a lo largo de un eje longitudinal, dicho extremo frontal (126) de dicho miembro alargado (124) comprende un miembro de base (126A) que tiene un miembro de cabeza (140) que se extiende desde un extremo frontal (126), dicho miembro de cabeza (140) incluye un miembro de borde (142) que se extiende a lo largo de su superficie frontal (144); (b) al menos un brazo de desviación que comprende una primera parte de brazo (182) que se extiende desde dicho miembro de base (126A) paralelo a dicho miembro de cabeza (140), caracterizado por que el vástago de émbolo comprende además una segunda parte de brazo (184) conectada a una parte delantera de dicha primera parte de brazo (182) que se extiende en dirección hacia atrás y hacia fuera con respecto a dicha primera parte de brazo (182), dicha segunda parte de brazo (184) es desviable radialmente hacia dentro durante la inserción de dicho vástago de émbolo (14) adentro del tapón (12) y se desvía hacia fuera hasta el contacto con una superficie interior (132) del tapón (12) tras la inserción en el tapón (12) para bloquear de manera segura dicho vástago de émbolo (14) dentro de dicho tapón (12), en donde la segunda parte de brazo (184) entra en un espacio recortado (134) del tapón (12) para bloquear el vástago de émbolo (14) en el sitio e impedir la separación del tapón (12) respecto al vástago de émbolo (14); y (c) al menos un primer miembro de tope (188) para limitar la desviación de dicha segunda parte de brazo (184) durante la inserción de dicho vástago de émbolo (14) en el tapón (12).

7. 发明专利

CA2794206C STOPPERS USED IN PRE-FILLED SYRINGES 未知
公开(公告)号：CA2794206C
公开(公告)日：2015-06-09
申请号：CA2794206
申请日：2011-03-25
申请人： BECTON DICKINSON CO
发明人： QUINN MICHAEL VINCENT , SCHILLER ERIC , JU GANG , GUAN E
IPC分类号： A61M5/315
摘要： A stopper (12) adapted for attachment with a plunger rod for use within a syringe barrel is disclosed. The stopper includes a main body (26) defining an open rearward end and a closed front end (30). The open rearward end is adapted to receive a front forward end attachment portion of the plunger rod. The stopper (12) also includes a core member (32) integrally formed with the main body (26) adjacent the closed front end (30). The core member (32) includes a nose portion (34) having a conical tip configured for entering an outlet opening of the syringe barrel. The closed front end of the stopper has a profile configured to cooperate with an internal surface of the syringe barrel wall to prevent reflux and reduce dead space within the barrel.

8. 发明专利

AU2008261086B2 Stopper and plunger rod for a pre-filled syringe 未知
公开(公告)号：AU2008261086B2
公开(公告)日：2011-04-07
申请号：AU2008261086
申请日：2008-06-04
申请人： BECTON DICKINSON CO
发明人： TORRES JOHANNA , GUAN E , SCHILLER ERIC , JU GANG , QUINN MICHAEL , ECONOMOU ANTHONY
IPC分类号： A61M5/315
摘要： A plunger rod adapted for attachment with a stopper for use with a syringe barrel is disclosed. The plunger rod includes an elongated member having a front end and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm associated with the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.

9. 发明专利

CA2830554A1 POSITIVE DISPLACEMENT STOPPER FOR A PRE- FILLED SYRINGE 未知
公开(公告)号：CA2830554A1
公开(公告)日：2008-12-11
申请号：CA2830554
申请日：2008-06-04
申请人： BECTON DICKINSON CO
发明人： SCHILLER ERIC , QUINN MICHAEL , TORRES JOHANNA , GUAN E , ENONOMOU ANTHONY , JU GANG
IPC分类号： A61M5/315
摘要： A plunger rod adapted for attachment with a stopper for use with a syringe barrel is disclosed. The plunger rod includes an elongated member having a front end and a back end, the plunger rod extending along a longitudinal axis. The plunger rod includes at least one deflecting arm associated with the front end of the elongated member. The deflecting arm is capable of deflecting radially inward during insertion of the plunger rod into a stopper, and deflecting outward into contact with an inner surface of the stopper after insertion to lock the plunger rod within the stopper.

10. 发明专利

CA2689122A1 POSITIVE DISPLACEMENT STOPPER FOR A PRE-FILLED SYRINGE 未知
公开(公告)号：CA2689122A1
公开(公告)日：2008-12-11
申请号：CA2689122
申请日：2008-06-04
申请人： BECTON DICKINSON CO
发明人： JU GANG , QUINN MICHAEL , GUAN E , ECONOMOU ANTHONY , TORRES JOHANNA , SCHILLER ERIC
IPC分类号： A61M5/315
摘要： A stopper (12) adapted for attachment with a plunger rod (14) for use wit hin a syringe barrel (16) is disclosed. The stopper includes a main body (26 ) defining an open rearward end (28) and a closed front end (30). The open r earward end is adapted to receive a front forward end attachment portion (31 ) of the plunger rod. The stopper also includes a core member (32) integrall y formed with said main body adjacent the closed front end. The core member includes a nose portion (34) having a profile adapted to create a positive s eal with an outlet opening of such syringe barrel.

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