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1. 发明申请

WO02055142B1 INHALER WITH FRANGIBLE MEMBRANES 审中-公开
标题翻译：吸入与可变膜
公开(公告)号：WO02055142B1
公开(公告)日：2003-02-13
申请号：PCT/US0200436
申请日：2002-01-09
申请人： BECTON DICKINSON CO , CONNELLY ROBERT I , SULLIVAN VINCENT J , SHERMER CHARLES D , WILLS ANJANA BHUTA , PETTIS RONALD J
发明人： CONNELLY ROBERT I , SULLIVAN VINCENT J , SHERMER CHARLES D , WILLS ANJANA BHUTA , PETTIS RONALD J
IPC分类号： A61J1/06 , A61J7/00 , A61M11/06 , A61M15/00 , B05B11/06
CPC分类号： A61M15/0028 , A61M11/002 , A61M11/003 , A61M11/02 , A61M15/0025 , A61M15/0031 , A61M15/0033 , A61M15/004 , A61M15/0041 , A61M15/0068 , A61M2202/064 , A61M2205/075 , A61M2207/00 , B05B11/061 , B05B11/062
摘要： A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive t the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.
摘要翻译：用于向使用者施用药物的药物输送装置包括药物储存器和每个设置在储存器附近的入口和出口。邻近入口设置的气室。该装置包括可操作以将所述气室加压至少规定压力的加压机构。第一个易碎膜延伸穿过入口端口，并将储存器与气室隔开。第二个易碎膜延伸穿过出口。当附加加压机构时，第一和第二膜中的至少一个响应于气室中的规定压力而爆裂，以允许气体流过入口和储存器，并将药物运送通过出口。

2. 发明申请

WO02055142A3 INHALER WITH FRANGIBLE MEMBRANES 审中-公开
标题翻译：吸入与可变膜
公开(公告)号：WO02055142A3
公开(公告)日：2002-12-19
申请号：PCT/US0200436
申请日：2002-01-09
申请人： BECTON DICKINSON CO , CONNELLY ROBERT I , SULLIVAN VINCENT J , SHERMER CHARLES D , WILLS ANJANA BHUTA , PETTIS RONALD J
发明人： CONNELLY ROBERT I , SULLIVAN VINCENT J , SHERMER CHARLES D , WILLS ANJANA BHUTA , PETTIS RONALD J
IPC分类号： A61J1/06 , A61J7/00 , A61M11/06 , A61M15/00 , B05B11/06
CPC分类号： A61M15/0028 , A61M11/002 , A61M11/003 , A61M11/02 , A61M15/0025 , A61M15/0031 , A61M15/0033 , A61M15/004 , A61M15/0041 , A61M15/0068 , A61M2202/064 , A61M2205/075 , A61M2207/00 , B05B11/061 , B05B11/062
摘要： A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive t the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.
摘要翻译：用于向使用者施用药物的药物输送装置包括药物储存器和每个设置在储存器附近的入口和出口。邻近入口设置的气室。该装置包括可操作以将所述气室加压至少规定压力的加压机构。第一个易碎膜延伸穿过入口端口，并将储存器与气室隔开。第二个易碎膜延伸穿过出口。当附加加压机构时，第一和第二膜中的至少一个响应于气室中的规定压力而爆裂，以允许气体流过入口和储存器，并将药物运送通过出口。

3. 发明专利

JP2006021055A Low-profile automatic injection device with self-emptying reservoir 有权
标题翻译：带自动储存器的低剖面自动注入装置
公开(公告)号：JP2006021055A
公开(公告)日：2006-01-26
申请号：JP2005245735
申请日：2005-08-26
申请人： Becton Dickinson & Co , ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company
发明人： SAGE BURTON H , CONNELLY ROBERT I
IPC分类号： A61M5/142 , A61M5/20 , A61M5/145 , A61M5/28 , A61M37/00
CPC分类号： A61M5/14586 , A61M5/14248 , A61M2005/14252 , A61M2005/1426
摘要： PROBLEM TO BE SOLVED: To provide an automatic injection device which is small in size and has a low-profile shape, thereby allows a walking patient to conveniently handle the device to be able to inject a medical solution, or the like, into the skin of a patient for a long term, and has a basic design to be simply and inexpensively manufactured. SOLUTION: This device 20 for delivering a liquid therapeutic preparation into the body of the patient by injection into or through the skin of the patient comprises a low-profile housing having a bottom surface 24 adapted to be brought into contact with the skin of the patient. A reservoir is disposed within the housing for containing the liquid therapeutic preparation to be administered. An injection needle is carried by a movable needle carrier which is disposed in the housing. The injection needle has a bent injection end which is adapted to project through a needle aperture in the bottom surface of the housing. The height of the housing is minimized. As a result, the housing is sufficiently low in height to allow the device to be worn inconspicuously under the clothing of the patient. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了提供一种尺寸小且具有小外形的自动注射装置，从而允许步行患者方便地处理该装置以能够注射医用溶液等，长期进入患者的皮肤，并且具有简单且廉价地制造的基本设计。解决方案：用于通过注入或穿过患者皮肤将液体治疗制剂输送到患者体内的该装置20包括具有适于与皮肤接触的底表面24的低轮廓外壳的病人。储存器设置在壳体内以容纳要施用的液体治疗剂。注射针由设置在壳体中的可动针架承载。注射针具有弯曲的注射端，其适于突出穿过壳体底表面中的针孔。外壳的高度最小化。结果，壳体的高度足够低以允许装置在患者的衣服下不明显地穿着。版权所有（C）2006，JPO＆NCIPI

4. 发明专利

JPH11313889A LOW-PROFILE AUTOMATIC INJECTION DEVICE WITH SELF-DISCHARGE RESERVOIR 失效
公开(公告)号：JPH11313889A
公开(公告)日：1999-11-16
申请号：JP4080399
申请日：1999-02-19
申请人： BECTON DICKINSON CO
发明人： SAGE BURTON H , CONNELLY ROBERT I
IPC分类号： A61M5/20 , A61M5/142 , A61M5/145 , A61M5/28
摘要： PROBLEM TO BE SOLVED: To provide an automatic injection device of simple, inexpensive basic design from the manufacturing point of view, conveniently handled by a walking patient because of its small dimensions and a low profile shape and capable of injecting a medicinal solution or the like in the skin of the patient over a long period of time. SOLUTION: A device 20 for administering a therapeutic liquid preparation into a body of a patient by injection piercing the skin of the patient is provided with a low-profile housing with a bottom face 24 that can come in contact with the skin of the patient, and a reservoir for storing the administered therapeutic liquid preparation is disposed in the housing. A needle is carried by a movable needle carrier in the housing and has a bent injection end protrusible piercing a needle aperture opened in the bottom face of the housing. As a result of minimizing the height of the housing, the height of the housing is sufficiently low, and this device can be inconspicuously mounted under the clothes of the patient.

5. 发明专利

JP2009207925A Microdevice interface for delivering or withdrawing substance through skin of animal 有权
标题翻译：用于通过动物皮肤递送或取出物质的MICRODEVICE接口
公开(公告)号：JP2009207925A
公开(公告)日：2009-09-17
申请号：JP2009148739
申请日：2009-06-23
申请人： Becton Dickinson & Co , ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company
发明人： CONNELLY ROBERT I , PETTIS RONALD J
IPC分类号： A61B5/151 , A61M37/00 , A61B5/15 , A61K9/22
CPC分类号： A61M37/0015 , A61B5/14514 , A61M2037/0023 , A61M2037/003
摘要： PROBLEM TO BE SOLVED: To enhance the puncturing property of a microneedle array in a microdevice interface for delivering or withdrawing a substance through the skin of a patient.
SOLUTION: The device for withdrawing or delivering a substance through the skin of a patient includes a body (12) and a skin puncturing device (14) having a plurality of skin puncturing members. The body (12) includes a bottom surface having a first inner surface area (32) supporting the skin puncturing device (14) and a second outer surface area(34) having an adhesive (38) for attaching the device to the skin. The first inner surface is spaced outwardly from the body (12).
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：为了提高微器件界面中的微针阵列的穿刺性能，用于将物质递送或取出通过患者的皮肤。解决方案：用于通过患者皮肤抽出或递送物质的装置包括具有多个皮肤穿刺构件的身体（12）和皮肤穿刺装置（14）。主体（12）包括具有支撑皮肤穿刺装置（14）的第一内表面区域（32）的底表面和具有用于将装置附接到皮肤的粘合剂（38）的第二外表面区域（34）。第一内表面与主体（12）向外间隔开。版权所有（C）2009，JPO＆INPIT

6. 发明专利

JP2002126092A PORTABLE STORAGE TYPE DRUG INFUSION DEVICE 审中-公开
公开(公告)号：JP2002126092A
公开(公告)日：2002-05-08
申请号：JP2001230533
申请日：2001-07-30
申请人： BECTON DICKINSON CO
发明人： CONNELLY ROBERT I , SHERMER CHARLES D , POWELL KENNETH G
IPC分类号： A61M5/00 , A61K9/22 , A61M1/36 , A61M5/142 , A61M5/145 , A61M5/168 , A61M37/00
摘要： PROBLEM TO BE SOLVED: To provide a portable drug infusion device which can accurately control a required critical dosage of a drug like insulin. SOLUTION: A piezoelectric valve or a pump structure is used by combining a thermal flow sensor and a closed loop control circuit that controls a required flow. The drug infusion device 30 is made in extremely small dimensions and closely controls a flow of insulin and other drugs. This device is structurally divided into two sections, namely a section for recycling expensive electronic components 34 and a section for disposable liquid delivery components that can be separated 32, so that the device can be costly reduced, a drug can be thoroughly sterilized and the contamination of recycling liquids can be prevented by limiting the flow routes of disposable liquids. Thus, it is possible to electronically control the variation of drug flows by changing the flow and/or a flow programming, thereby conforming to the variation of requirements of a patient, time and delivery rate.

7. 发明专利

ES2265486T3 INHALADOR CON MEMBRANAS FRANGIBLES. 未知
公开(公告)号：ES2265486T3
公开(公告)日：2007-02-16
申请号：ES02701918
申请日：2002-01-09
申请人： BECTON DICKINSON CO
发明人： CONNELLY ROBERT I , SULLIVAN VINCENT J , SHERMER CHARLES D , WILLS ANJANA BHUTA , PETTIS RONALD J
IPC分类号： A61J1/06 , A61M15/00 , A61J7/00 , A61M11/06 , B05B11/06
摘要： Un dispositivo (101, 901, 1001, 1101, 1201, 1301) de suministro de medicamentos para administrar un medicamento (5) a un usuario, comprendiendo dicho dispositivo: a) un depósito (166, 866) del medicamento; b) un orificio de entrada (114, 714) y un orificio de salida (118, 418), cada uno de ellos dispuesto adyacente a dicho depósito (166, 866); c) una cámara de gas (112, 612) dispuesta adyacente a dicho orificio de entrada (114, 714); d) un mecanismo compresor (110, 610) accionable para comprimir dicha cámara de gas (112, 612) hasta al menos una presión preestablecida; e) una primera membrana frangible (152, 252, 352, 552, 652, 752} que se extiende a través de dicho orificio de entrada (114, 714) y que separa dicho depósito (166, 866) y dicha cámara de gas (112, 612); caracterizado por f) una segunda membrana frangible (154, 254, 354, 454, 554, 654, 754) que se extiende a través de dicho orificio de salida (118, 418); g) en el que, cuando se acciona dicho mecanismo compresor (110, 610), al menos una de dichas primera y segunda membranas es sensible a dicha presión preestablecida existente en dicha cámara de gas (112, 612) de modo que estalla para dejar que fluya el gas (111) a través de dicho orificio de entrada (114, 714) y de dicho depósito (166, 866) y arrastre el medicamento (5) por dicho orificio de salida (118, 418).

8. 发明专利

DK1351735T3 未知
公开(公告)号：DK1351735T3
公开(公告)日：2006-09-11
申请号：DK02701918
申请日：2002-01-09
申请人： BECTON DICKINSON CO
发明人： CONNELLY ROBERT I , SHERMER CHARLES D , SULLIVAN VINCENT J , WILLS ANJANA BHUTA , PETTIS RONALD J
IPC分类号： A61J1/06 , A61M15/00 , A61J7/00 , A61M11/06 , B05B11/06
摘要： A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive to the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.

9. 发明专利

AT326995T 未知
公开(公告)号：AT326995T
公开(公告)日：2006-06-15
申请号：AT02701918
申请日：2002-01-09
申请人： BECTON DICKINSON CO
发明人： CONNELLY ROBERT I , SULLIVAN VINCENT J , SHERMER CHARLES D , WILLS ANJANA BHUTA , PETTIS RONALD J
IPC分类号： A61J1/06 , A61J7/00 , A61M11/06 , A61M15/00 , B05B11/06
摘要： A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive to the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.

10. 发明专利

DE60105922T2 未知
公开(公告)号：DE60105922T2
公开(公告)日：2006-03-02
申请号：DE60105922
申请日：2001-07-23
申请人： BECTON DICKINSON CO
发明人： CONNELLY ROBERT I , POWELL KENNETH G , SHERMER CHARLES D
IPC分类号： A61M5/00 , A61K9/22 , A61M1/36 , A61M5/142 , A61M5/145 , A61M5/152 , A61M5/168 , A61M37/00

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