专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2009149397A3 RESPIRATORY SYNCYTIAL VIRUS RENDERS DENDRITIC CELLS TOLEROGENIC 审中-公开
标题翻译：呼吸道同类病毒Renders DENDRITIC CELLS TOLEROGENIC
公开(公告)号：WO2009149397A3
公开(公告)日：2010-03-25
申请号：PCT/US2009046482
申请日：2009-06-05
申请人： BAYLOR RES INST , CONNOLLY JOHN E , BANCHEREAU JACQUES F , GILL MICHELLE A
发明人： CONNOLLY JOHN E , BANCHEREAU JACQUES F , GILL MICHELLE A
IPC分类号： A61K39/12 , A61P3/10 , A61P19/02 , A61P31/12
CPC分类号： A61K39/001 , A61K2035/122 , A61K2039/5154 , C12N5/064 , C12N2760/16111 , C12N2760/18511
摘要： The present invention includes compositions, methods and systems for inducing immune tolerance using antigen presenting cells by infecting isolated antigen presenting cells with an effective amount of respiratory syncytial virus (RSV) or portions thereof sufficient to infect the antigen presenting cells and contacting CD4+, CD8+ or both CD4+ T cells and CD8+ T cells with the RSV-infected antigen presenting cells, wherein the CD4+, CD8+ or both CD4 and CD8+ T cells are rendered tolerogenic as measured in vitro by a mixed leukocyte reaction.
摘要翻译：本发明包括用抗原呈递细胞诱导免疫耐受的组合物，方法和系统，其通过用有效量的呼吸道合胞病毒（RSV）或其部分感染分离的抗原呈递细胞，其足以感染抗原呈递细胞并接触CD4 +，CD8 +或具有RSV感染的抗原呈递细胞的CD4 + T细胞和CD8 + T细胞都是CD4 +，CD8 +或CD4 + CD8 + T细胞都具有耐受性，通过混合白细胞反应体外测定。

2. 发明公开

EP2307047A4 RESPIRATORY SYNCYTIAL VIRUS RENDERS DENDRITIC CELLS TOLEROGENIC 审中-公开
标题翻译：呼吸道合胞病毒使树突状细胞容易感染
公开(公告)号：EP2307047A4
公开(公告)日：2011-09-07
申请号：EP09759555
申请日：2009-06-05
申请人： BAYLOR RES INST
发明人： CONNOLLY JOHN E , BANCHEREAU JACQUES F , GILL MICHELLE A
IPC分类号： A61K39/12 , A61P3/10 , A61P19/02 , A61P31/12
CPC分类号： A61K39/001 , A61K2035/122 , A61K2039/5154 , C12N5/064 , C12N2760/16111 , C12N2760/18511
摘要： The present invention includes compositions, methods and systems for inducing immune tolerance using antigen presenting cells by infecting isolated antigen presenting cells with an effective amount of respiratory syncytial virus (RSV) or portions thereof sufficient to infect the antigen presenting cells and contacting CD4+, CD8+ or both CD4+ T cells and CD8+ T cells with the RSV-infected antigen presenting cells, wherein the CD4+, CD8+ or both CD4 and CD8+ T cells are rendered tolerogenic as measured in vitro by a mixed leukocyte reaction.

3. 发明专利

CA2728423A1 RESPIRATORY SYNCYTIAL VIRUS RENDERS DENDRITIC CELLS TOLEROGENIC 未知
公开(公告)号：CA2728423A1
公开(公告)日：2009-12-10
申请号：CA2728423
申请日：2009-06-05
申请人： BAYLOR RES INST
发明人： CONNOLLY JOHN E , BANCHEREAU JACQUES F , GILL MICHELLE A
IPC分类号： A61K39/12 , A61K35/12 , A61K39/00 , A61P3/10 , A61P19/02 , A61P31/12
摘要： The present invention includes compositions, methods and systems for inducing immune tolerance using antigen presenting cells by infecting isolated antigen presenting cells with an effective amount of respiratory syncytial virus (RSV) or portions thereof sufficient to infect the antigen presenting cells and contacting CD4+, CD8+ or both CD4+ T cells and CD8+ T cells with the RSV-infected antigen presenting cells, wherein the CD4+, CD8+ or both CD4 and CD8+ T cells are rendered tolerogenic as measured in vitro by a mixed leukocyte reaction.

4. 发明专利

NZ589777A RESPIRATORY SYNCYTIAL VIRUS RENDERS DENDRITIC CELLS TOLEROGENIC 未知
公开(公告)号：NZ589777A
公开(公告)日：2012-07-27
申请号：NZ58977709
申请日：2009-06-05
申请人： BAYLOR RES INST
发明人： CONNOLLY JOHN E , BANCHEREAU JACQUES F , GILL MICHELLE A
IPC分类号： A61K39/12 , A61K35/12 , A61K39/00 , A61P3/10 , A61P19/02 , A61P31/12
摘要： Disclosed is the use of isolated antigen presenting cells that are infected with an effective amount of respiratory syncytial virus (RSV) in the manufacture of a medicament for inducing immune tolerance in a patient afflicted with autoimmune disease, whereby isolated antigen presenting cells are infected with an effective amount of respiratory syncytial virus (RSV) or portions thereof sufficient to infect the antigen presenting cells, and wherein the medicament is used for contacting with CD4+, CD8+ or both CD4+ T cells and CD8+ T cells, wherein the CD4+, CD8+ or both CD4 and CD8+ T cells are rendered tolerogenic as measured in vitro by a mixed leukocyte reaction, wherein the autoimmune disease is insulin-dependent diabetes mellitus, multiple sclerosis, autoimmune encephalomyelitis, rheumatoid arthritis, autoimmune arthritis, myasthenia gravis, thyroiditis, uveoretinitis, Hashimoto's thyroiditis, primary myxoedema, thyrotoxicosis, pernicious anaemia, autoimmune atrophic gastritis, Addison's disease, juvenile diabetes, Goodpasture's syndrome, pemphigus vulgaris, pemphigoid, psoriasis sympathetic ophthalmia, phacogenic uveitis, autoimmune haemolytic anaemia, idiopathic leucopenia, primary biliary cirrhosis, active chronic hepatitis, cryptogenic cirrhosis, ulcerative colitis, Sjogren's syndrome, scleroderma, Wegener's granulomatosis, poly/dermatomyositis, discoid lupus erythematosus or systemic lupus erythematosus

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式