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    • 7. 发明专利
    • 3'-alkoxy spirocyclic tetramic and tetronic acids
    • ZA200610747B
    • 2008-07-30
    • ZA200610747
    • 2006-12-20
    • BAYER CROPSCIENCE AG
    • REINER FISCHEROLIVER GAERTZENSTEFAN LEHRTHOMAS BRETSCHNEIDERDIETER FEUCHTOLGA MALSAMCHRISTIAN ARNOLDTHOMAS AULERJEFFREY HILLS MARTINHEINZ KEHNECHRIS ROSINGER
    • A01N20090101A61K20090101C07D20090101C07D209/54C07D307/94
    • 1-Oxa- or 1-azaspiro[4.5]dec-3-ene derivatives (I) are new. 1-Oxa- or 1-azaspiro[4.5]dec-3-ene derivatives of formula (I) are new. W : H, (halo)alkyl, halo, (halo)alkoxy or CN; X : (halo)alkyl, halo, (halo)alkoxy or CN; Y : H, (halo)alkyl, halo, (halo)alkoxy or CN in the 4 position; Z : H; W : H, halo or alkyl; X : (halo)alkyl, halo, (halo)alkoxy or CN; Y : optionally substituted phenyl or heteroaryl in the 4 position; Z : H; W : H, halo or alkyl; X : (halo)alkyl, halo, (halo)alkoxy or CN; Y : optionally substituted phenyl or heteroaryl in the 5 position; Z : H, alkyl or halo in the 4 position; W : H, Me, Pr, iPr, halo, CN or CF 3; X : (halo)alkyl, halo, (halo)alkoxy or CN; Y = alkyl in the 4 position; Z : H; W : H, halo, alkyl or alkoxy; X : (halo)alkyl, halo, (halo)alkoxy or CN; Y : H, halo, (halo)alkyl or haloalkoxy in the 4 position; Z : halo, (halo)alkyl, CN or (halo)alkoxy in the 3 or 5 position; A : optionally substituted alkanediyl, cycloalkyl or heterocycloalkyl; B : H or optionally substituted alkyl, alkenyl, alkoxy, alkoxyalkoxy, phenyl, or cycloalkyl optionally interrupted by heteroatoms and/or CO; D : NH or O; Q 1>H or optionally substituted alkyl, alkoxy, alkoxyalkyl, alkylthioalkyl, cycloalkyl, heterocycloalkyl, phenyl, heteroaryl, phenylalkyl or heteroarylalkyl; Q 2>H or alkyl; CQ 1>Q 2>an optionally substituted 3-6C ring optionally interrupted by a heteroatom; G : H, COR 1>, C(L)MR 2>, SOI 2R 3>, P(L)R 4>R 5>, E or C(L)NR 6>R 7>; E : a metal or ammonium ion; L, M : O or S; R 1>alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl or polyalkoxyalkyl, each optionally substituted with halo or CN; cycloalkyl or heterocyclyl, each optionally substituted with halo, alkyl or alkoxy; or optionally substituted phenyl, phenylalkyl, heteroaryl, phenoxyalkyl or heteroaryloxyalkyl; R 2>alkyl, alkenyl, alkoxyalkyl or polyalkoxyalkyl, each optionally substituted with halo or CN; or optionally substituted cycloalkyl, phenyl or benzyl; R 3>-R 5>alkyl, alkoxy, alkylamino, dialkylamino, alkylthio, alkenylthio or cycloalkylthio, each optionally substituted with halo; or optionally substituted phenyl, benyl, phenoxy or phenylthio; R 6>, R 7>H; alkyl, cycloalkyl, alkenyl, alkoxy or alkoxyalkyl, each optionally substituted with halo or CN; or optionally substituted phenyl or benzyl; or together form an optionally substituted ring optionally containing O or S. Independent claims are also included for: (1) a process for preparing (I); (2) composition comprising at least one compound (I) and at least one of a list of safeners; (3) intermediates of formula (II), (XVI), (XIV), (XVII), (XIX), (XVIII), (III) and (XX). R 8>alkyl. [Image] [Image] [Image] [Image] [Image] [Image] [Image] [Image] [Image] ACTIVITY : Herbicide; Insecticide; Acaricide; Plant antifungal. 7-Butoxy-4-hydroxy-3-(2,4,6-trimethylphenyl)-1-azaspiro[4.5]dec-3-en-2-one gave at least 70% control of Avena sativa, Lolium multiflorus and Staria viridis in a post-emergence test at an application rate of 320 g/ha. MECHANISM OF ACTION : None given.