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    • 4. 发明专利
    • 1,3-dimethylbutyl carboxanilides for controlling undesirable micro-organism
    • ZA200603103B
    • 2007-07-25
    • ZA200603103
    • 2006-04-19
    • BAYER CROPSCIENCE AG
    • RALF DUNKELHANS-LUDWIG ELBENICO GREUL JOERGBENOIT HARTMANULRIKE WACHENDORFF-NEUMANNPETER DAHMENKARL-HEINZ KUCK
    • A01N20090101A01N43/08A01N43/10A01N43/32A01N43/40A01N43/56A01N43/60A01N43/78A01N43/82C07D20090101C07D213/82C07D231/14C07D231/16C07D277/56C07D307/68C07D327/06C07D333/38
    • 1,3-Dimethylbutyl carboxanilides (I) are new. 1,3-Dimethylbutyl carboxanilides of formula (I) are new. [Image] R 1> : H, 1-8C alkyl, 1-6C alkylsulfinyl, 1-6C alkylsulfonyl, (1-4C)alkoxy(1-4C)alkyl, 3-8C cycloalkyl, 1-6C haloalkyl, 1-4C haloalkylthio, 1-4C haloalkylsulfinyl, 1-4C haloalkylsulfonyl, CHO; 1-3C alkyl substituted with CHO, 2-4C alkanoyl, 1-3C alkoxycarbonyl, 2-4C haloalkanoyl or 1-3C haloalkoxycarbonyl; COR, COCOR 3>, CONR 4>R 5> or CH 2NR 6>R 7>; R : 1-8C alkyl, 1-8C alkoxy, (1-4C)alkoxy(1-4C)alkyl, 3-8C cycloalkyl, 1-6C haloalkyl, 1-6C haloalkoxy, halo(1-4C)alkoxy(1-4C)alkyl or 3-8C halocycloalkyl; R 2> : H, F, Cl, Me or CF 3; R 3> : H or R; R 4>, R 5> : H, 1-8C alkyl, (1-4C)alkoxy(1-4C)alkyl, 3-8C cycloalkyl, 1-6C haloalkyl, halo(1-4C)alkoxy(1-4C)alkyl or 3-8C halocycloalkyl, or NR 4>R 5> is a saturated 5- to 8-membered heterocycle with 0-2 other heteroatoms (O, S or NR 8>), optionally substituted with halo or 1-4C alkyl; R 6>, R 7> : H, 1-8C alkyl, 3-8C cycloalkyl, 1-8C haloalkyl or 3-8C halocycloalkyl, or NR 6>R 7> is a saturated 5- to 8-membered heterocycle with 0-2 other heteroatoms (O, S or NR 8>), optionally substituted with halo or 1-4C alkyl; R 8> : H or 1-6C alkyl; A : a heterocyclic group of formula A1-A14. [Image] [Image] [Image] [Image] R 9> : H, OH, CHO, CN, F. Cl, Br, NO 2, 1-4C (halo)alkyl, 1-4C (halo)alkoxy, 1-4C (halo)alkylthio, CONH 2 or carbamoyl(1-4C)alkyl; R 1> 0> : H, Cl, Br, I, CN, 1-4C alkyl, 1-4C alkoxy or 1-4C (halo)alkylthio; R 1> 1> : H, 1-4C alkyl, 1-4C hydroxyalkyl, 2-6C alkenyl, 3-6C cycloalkyl, (1-4C)(halo)alkylthio(1-4C)alkyl or (1-4C)(halo)alkoxy(1-4C)alkyl; R 1> 2>, R 1> 3>, R 1> 5>, R 1> 6> : H, halo or 1-4C (halo)alkyl; R 1> 4> : halo, CN, 1-4C (halo)alkyl or 1-4C haloalkoxy; R 1> 7> : H or 1-4C (halo)alkyl; R 1> 8> : halo, OH, CN, 1-4C (halo)alkyl, 1-4C (halo)alkoxy or 1-4C (halo)alkylthio; R 1> 9> : H, halo, CN, 1-4C (halo)alkyl, 1-4C (halo)alkoxy, 1-4C alkylsulfinyl or 1-4C alkylsulfonyl; R 2> 0>, R 2> 1> : 1-4C (halo)alkyl; R 2> 2>, R 2> 3> : H, halo, NH 2 or 1-4C (halo)alkyl; R 2> 4> : H or 1-4C (halo)alkyl; R 2> 5>, R 2> 6> : H, halo, NH 2, NO 2 or 1-4C (halo)alkyl; R 2> 8> : H, halo, NH 2, mono- or di(1-4C)alkylamino, CN or 1-4C (halo)alkyl; R 2> 9> : halo, OH, 1-4C (halo)alkyl, 1-4C (halo)alkoxy or 3-6C cycloalkyl; R 3> 0> : H, halo, NH 2, mono- or di(1-4C)alkylamino, CN or 1-4C (halo)alkyl; R 3> 1>, R 27> : halo or 1-4C (halo)alkyl; R 3> 2> : H, halo or 1-4C (halo)alkyl; R 3> 3> : halo, OH, 1-4C (halo)alkyl, 1-4C (halo)alkoxy or 1-4C (halo)alkylthio; R 3> 4> : 1-4C alkyl; provided that R 9> is not CF 2, CHF 2, Me or Et when R 1> 0> : H or Cl, R 1> 1> = Me and R 1> = R 2> = H; R 9> is not Me, CF 2Cl, CF 3, CHF 2, Cl or Br when R 1> 0> = H, F, CF 3 or Me, R 1> 1> = Me, CF 3, CH 2OMe or CH 2OCF 3 and R 1> = COR with R = 1-6C alkyl, 1-6C alkoxy, (1-4C)alkoxy(1-4C)alkyl, 1-6C haloalkyl, 1-6C haloalkoxy or halo(1-4C)alkoxy(1-4C)alkyl; R 1> 4> is not Me when R 1> 2> and R 1> 3> = H or Me and R 1> = R 2> = H; R 1> 8> is not CF 3, Me, Cl or SMe when R 1> 9> is H and R 1> = R 2> = H; R 1> 8> is not Me, CF 2Cl, CF 3, CHF 2, Cl or Br when R 1> 9> = H and R 1> = COR with R = 1-6C alkyl, 1-6C alkoxy, (1-4C)alkoxy(1-4C)alkyl, 1-6C haloalkyl, 1-6C haloalkoxy or halo(1-4C)alkoxy(1-4C)alkyl; R 1> and R 2> are not both H when A = A5; R 2> 4> is not Me when R 2> 2> and R 2> 3> = H or Me and R 1> = R 2> = H; R 2> 9> is not Me, CF 2Cl, CF 3, CHF 2, Cl or Br when R 2> 8> = Me, CF 3, CH 2OMe or CH 2OCF 3 and R 1> = COR with R = 1-6C alkyl, 1-6C alkoxy, (1-4C)alkoxy(1-4C)alkyl, 1-6C haloalkyl, 1-6C haloalkoxy or halo(1-4C)alkoxy(1-4C)alkyl; R 3> 2> is not Cl when R 1> = R 2> = H. An independent claim is also included for a process for preparing (I). ACTIVITY : Plant antifungal; Plant antibacterial; Fungicide. In a protective test against Podosphaera leucotricha on young apple trees, 4-chloro-N-(2-(1,3-dimethylbutyl)phenyl)-5-thiazolecarboxamide had an activity of 100% at an application rate of 100 g/ha. MECHANISM OF ACTION : None given.
    • 6. 发明专利
    • 2-alkyl-cycloalk(en)yl-carboxamides
    • ZA200704636B
    • 2008-09-25
    • ZA200704636
    • 2007-06-08
    • BAYER CROPSCIENCE AG
    • RALF DUNKELHANS-LUDWIG ELBENICO GREUL JOERGBENOIT HARTMANNHERBERT GAYERTHOMAS SEITZULRIKE WACHENDORFF-NEUMANNPETER DAHMENKARL-HEINZ KUCK
    • A01N20090101C07C20090101C07D20090101C07F20090101
    • 2-Alkyl-cycloalk(en)yl-carboxamide compounds (I) are new. 2-Alkyl-cycloalk(en)yl-carboxamide compounds (I) of formula (A-CO-N(R 1>)-L-CH 2(R 2>)-(CH 2) s-X) are new. X : -CR 3>R 4>R 5> or -SiR 49>R 50>R 51>; s : 1-2; R 1>H, 1-8C alkyl, 1-6C alkylsulfinyl, 1-6C alkylsulfonyl, 1-4C alkoxy-1-4C-alkyl, 3-8C cycloalkyl, 1-6C haloalkyl, 1-4C haloalkylthio, 1-4C haloalkylsulfinyl, 1-4C haloalkylsulfonyl, halo-1-4C-alkoxy-1-4C-alkyl, 3-8C halocycloalkyl (with 1-9 of F, Cl and/or Br), formyl, formyl-1-3C-alkyl, (1-3C-alkyl)carbonyl-1-3C-alkyl, (1-3C-alkoxy)carbonyl-1-3C-alkyl, halo-(1-3C-alkyl)carbonyl-1-3C-alkyl, halo-(1-3C-alkoxy)carbonyl-1-3C-alkyl (with 1-13 of F, Cl and/or Br), (1-8C-alkyl)carbonyl, (1-8C-alkoxy)carbonyl, (1-4C-alkoxy-1-4C-alkyl)carbonyl, (3-8C-cycloalkyl)carbonyl, (1-6C-haloalkyl)carbonyl, (1-6C-haloalkoxy)carbonyl, (halo-1-4C-alkoxy-1-4C-alkyl)carbonyl, (3-8C-halocycloalkyl)carbonyl (with 1-9 of F, Cl and/or Br), -C(=O)C(=O)R 6>, -CONR 7>R 8> or -CH 2NR 9>R 10>; L : L 1> or L 2>; L 1>3-7C cycloalkyl-1,2-ene (3-7C-cycloalkyl-1,2-diyl) (optionally substituted by 1-4 of F, Cl, 1-4C alkyl or 1-4C haloalkyl); L 2>cyclohexenylene (cyclohexendiyl) (optionally substituted by 1-4 of F, Cl, 1-4C alkyl or 1-4C haloalkyl); R 2>H, halo, 1-4C alkyl or 1-4C haloalkyl with 1-9 of F, Cl and/or Br; either R 3>halo, 1-8C alkyl or 1-6C haloalkyl with 1-13 of F, Cl and/or Br; and R 4>halo, 1-8C alkyl or 1-6C haloalkyl with 1-13 of F, Cl and/or Br; or CR 3>R 4>3-6 membered, optionally unsaturated, carbocyclic or heterocyclic ring (optionally substituted with halo, 1-4C alkyl, 1-4C alkoxy, 1-4C haloalkyl or 1-4C haloalkoxy); R 5>H, halo, 1-8C alkyl or 1-6C haloalkyl with 1-13 of F, Cl and/or Br; R 49>, R 50>H, 1-8C alkyl, 1-8C alkoxy, 1-4C alkoxy-1-4C-alkyl, 1-4C alkylthio-1-4C-alkyl or 1-6C haloalkyl; R 51>phenyl, phenylalkyl (both optionally substituted), H, 1-8C alkyl, 1-8C alkoxy, 1-4C alkoxy-1-4C-alkyl, 1-4C-alkylthio-1-4C-alkyl, 2-8C alkenyl, 2-8C-alkynyl, 1-6C haloalkyl, 2-6C haloalkenyl, 2-6C haloalkynyl or 3-6C cycloalkyl; R 6>H, 1-8C alkyl, 1-8C alkoxy, 1-4C alkoxy-1-4C-alkyl, 3-8C cycloalkyl, 1-6C haloalkyl, 1-6C haloalkoxy, halo-1-4C-alkoxy-1-4C-alkyl or 3-8C-halocycloalkyl with 1-9 of F, Cl and/or Br; either R 7>, R 8>H, 1-8C alkyl, 1-4C alkoxy-1-4C-alkyl, 3-8C cycloalkyl, 1-8C haloalkyl, halo-1-4C-alkoxy-1-4C-alkyl or 3-8C-halocycloalkyl with 1-9 of F, Cl and/or Br; or NR 7>R 8>5-8 membered saturated heterocycle (optionally containing 1-2 further non-adjacent heteroatoms of O, S or NR 11>) optionally substituted with one or more halo or 1-4C alkyl; either R 9>, R 10>H, 1-8C alkyl, 3-8C cycloalkyl, 1-8C haloalkyl or 3-8C-halocycloalkyl with 1-9 of F, Cl and/or Br; or NR 9>R 10>5-8 membered saturated heterocycle (optionally containing 1-2 further non-adjacent heteroatoms of O, S or NR 11>), optionally substituted with halo or 1-4C alkyl; R 11>H or 1-6C alkyl; A : 19 (hetero)cyclic groups e.g. phenyl compound of formula (1), pyridine compound of formula (2) and thio compound of formula (3); R 21>H, halo, OH, CN, 1-6C alkyl; or 1-4C haloalkyl, 1-4C haloalkoxy or 1-4C haloalkylthio, each with 1-5 halo atoms; R 22>H, halo, OH, CN, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio; or 1-4C haloalkyl, 1-4C haloalkylthio or 1-4C haloalkoxy, each with 1-5 halo atoms; R 23>H, halo, OH, CN, 1-4C alkyl, 1-4C alkoxy, 1-4C alkylthio; or 1-4C haloalkyl, 1-4C haloalkoxy, each with1-5 halo atoms, 1-4C-alkylsulfinyl or 1-4C alkylsulfonyl; and R 26>1-4C alkyl or 1-4C haloalkyl with 1-5 halo atoms. Independent claims are also included for: (1) the preparation of (I); (2) agents for combating undesired microorganisms, comprising at least (I) with diluting agent and/or surface active agents; and (3) methods for combating undesired microorganisms, comprising applying (I) with diluting agent and/or surface active agents on the microorganisms and/or its habitat. [Image] ACTIVITY : Antibacterial; Antifungal. MECHANISM OF ACTION : None given.