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    • 5. 发明专利
    • New phenyl substituted 4-hydroxy-tetrahydropyridone derivatives useful for control of animal pests and as herbicides
    • DE10019145A1
    • 2001-10-25
    • DE10019145
    • 2000-04-18
    • BAYER AG
    • FISCHER REINERGRAFF ALANTRAUTWEIN AXELULLMANN ASTRIDSCHNEIDER UDOWISCHNAT RALFDREWES MARK-WILHELMERDELEN CHRISTOPHFEUCHT DIETER
    • A01M21/04A01N43/40A01N43/42A01N43/56A01N43/90B27K3/34B27K3/40C07C233/51C07C233/52C07D211/34C07D211/66C07D211/86C07D221/20C07D309/08C07D309/14C07D401/12C07D409/06C07D409/10C07D455/02C07D491/10C07D491/107C07D213/69C07D471/04
    • Phenyl-substituted 4-hydroxy-tetrahydropyridone derivatives are new. The phenyl-substituted 4-hydroxy-tetrahydropyridone derivatives are compounds of formula (I): W = H; alkyl; haloalkyl; alkenyl; alkynyl; or alkoxy; X = halo; alkyl; haloalkyl; alkoxy; haloalkoxy; alkenyl; alkynyl; CN; or phenyl, phenoxy, phenylthio, phenylalkoxy or phenylalkylthio (each optionally substituted); Y = H; alkyl; halo; alkoxy; alkenyl; alkynyl; or aryl or heteroaryl (each optionally substituted); Z = H; halo; alkyl; haloalkyl; alkoxy; haloalkoxy; or CN; A = H; alkyl, alkenyl or alkoxyalkyl (each optionally substituted with halo); cycloalkyl or cycloalkyl-alkyl (each optionally substituted and each with 1 or more ring atoms optionally replaced with a hetero atom); or aryl, aralkyl, heteroaryl or heteroarylalkyl (each optionally substituted with halo, alkyl, haloalkyl, alkoxy, haloalkoxy, CN or NO2); B = H or alkyl; D = H; alkenyl, alkynyl or alkoxyalkyl (each optionally substituted); or cycloalkyl or cycloalkyl-alkyl (each optionally substituted and each with 1 or more ring atoms optionally replaced with a hetero atom); or D and Q together form alkanediyl (optionally substituted with optionally substituted alkyl or alkoxy); Q = H; alkyl; alkoxyalkyl; or cycloalkyl or phenyl (each optionally substituted and optionally with 1 CH2 of cycloalkyl replaced with O or S); Q = H or alkyl; G = H; -C(O)R ; -C(L)-M-R ; -SO2-R ; -P(L)(R )(R ); E; or -C(L)-NR ; E = metal or ammonium ion; L and M = O or S; R = alkyl, alkenyl, alkoxyalkyl, alkylthioalkyl or polyalkoxyalkyl (each optionally substituted with alkyl); cycloalkyl (optionally substituted with halo, alkyl or alkoxy and each with 1 or more CH2 optionally replaced with a hetero atom); or phenyl, phenylalkyl, heteroaryl, phenoxyalkyl or heteroaryloxyalkyl (each optionally substituted); R = alkyl, alkenyl, alkoxyalkyl or polyalkoxyalkyl (each optionally substituted with halo); or cycloalkyl, phenyl or benzyl (each optionally substituted); R -R = alkyl, alkoxy, NH(alkyl), N(alkyl)2, alkylthio, alkenylthio or cycloalkylthio (each optionally substituted with halo); or phenyl, benzyl, phenoxy or phenylthio (each optionally substituted); R and R = H; alkyl, cycloalkyl, alkenyl, alkoxy or alkoxyalkyl (each optionally substituted with halo); or phenyl or benzyl (each optionally substituted); or NR R forms a ring optionally interrupted with O or S. C(A)(B) forms a saturated or unsaturated ring (optionally substituted and optionally containing 1 or more hetero a toms); CQ Q forms a saturated or unsaturated ring (optionally substituted and optionally containing a hetero atom).
    • 8. 发明专利
    • New thiazolyl-substituted pyranone or pyridone derivatives, useful as total or selective herbicides and pesticides, e.g. insecticides, acaricides, nematocides, ectoparasiticides or antifouling agents
    • DE10100175A1
    • 2002-07-11
    • DE10100175
    • 2001-01-04
    • BAYER AG
    • FISCHER REINERULLMANN ASTRIDTRAUTWEIN AXELDREWES MARK-WILHELMERDELEN CHRISTOPHDAHMEN PETERFEUCHT DIETERPONTZEN ROLFLOESEL PETER
    • C07D277/20A01N43/78A01N47/16C07D277/30C07D417/04C07D417/06C07D417/12C07D417/14C07D491/052C07D491/107C07D471/04C07D309/02C07D309/36C07D311/06
    • 3-Thiazolyl-4-hydroxy-5,6-dihydropyrone or 3-thiazolyl-4-hydroxy-tetrahydropyridone derivatives (I) are new. 3-Thiazolyl-4-hydroxy-5,6-dihydropyrone or 3-thiazolyl-4-hydroxy-tetrahydropyridone derivatives of formula (I) are new. Het = 5-membered nitrogen-containing heterocycle of the thiazole series (optionally substituted (os) by halo, alkyl, alkoxy, alkenyloxy, haloalkyl, haloalkoxy, haloalkenyloxy, CN, NO2, alkylthio, alkylsulfinyl, alkylsulfonyl, os phenyl or os phenoxy); W = O or N-D; A = H, alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl or alkylthioalkyl (all os by halo), saturated or unsaturated cycloalkyl (os) (optionally having at least one ring atom replaced by a heteroatom) or aryl, aralkyl or heteroaryl (all os by halo, alkyl, haloalkyl, alkoxy, haloalkoxy, CN or NO2); B' = H or alkyl; or CAB' = ring (os, saturated or unsaturated and optionally containing at least one heteroatom); D = H, alkyl, alkenyl, alkynyl, alkoxyalkyl, polyalkoxyalkyl, alkylthioalkyl, cycloalkyl (saturated or unsaturated and optionally having at least one ring atom replaced by a heteroatom), aryl, aralkyl, heteroaralkyl or heteroaryl (all os); or A + Q1 = alkanediyl (os by os alkyl or os alkoxy), in which two non-adjacent C atoms may be part of a further ring (os); or D + Q1 = group (os, saturated or unsaturated and optionally containing at least one heteroatom) completing a ring; Q1 = H, alkyl, alkoxyalkyl, cycloalkyl (os and optionally having one CH2 replaced by O or S) or phenyl (os); Q2 = H or alkyl; or CQ1Q2 = ring (os and optionally containing a heteroatom); G = H, COR1, C(L)MR2, SO2R3, P(L)R4R5, E or C(L)-NR6R7; E = metal or ammonium ion; L, M = O or S; R1 = alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl or alkylthioalkyl (all os by halo), cycloalkyl (optionally interrupted by at least one heteroatom and os by halo, alkyl or alkoxy), or phenyl, phenylalkyl, heteroaryl, phenoxyalkyl or heteroaryloxy (all os); R2 = alkyl, alkenyl, alkoxyalkyl or polyalkoxyalkyl (all os by halo) or cycloalkyl, phenyl or benzyl (all os); R3 = alkyl, haloalkyl, phenyl (os) or benzyl (os); R4, R5 = alkyl, alkoxy, mono- or dialkylamino, alkylthio, alkenylthio or cycloalkylthio (all os by halo) or phenyl, benzyl, phenoxy or phenylthio (all os); R7, R8 = H, alkyl, cycloalkyl, alkenyl, alkoxy or alkoxyalkyl (all os by halo) or phenyl or benzyl (both os); and NR7R8 = heterocycle (optionally interrupted by O or S). Independent claims are included for: (1) Preparation of (I); and (2) New amide, ester and nitrile intermediates of formulae (II) and (XX). R8 = alkyl or H. Provided that R8 is H, when W is N-D.
    • 9. 发明专利
    • New phenyl-substituted 5,6-dihydro-pyrone derivatives, useful as total or selective herbicides, insecticides, acaricides, nematocides, ectoparasiticides or antifouling agents
    • DE10030094A1
    • 2001-12-20
    • DE10030094
    • 2000-06-19
    • BAYER AG
    • FISCHER REINERGRAFF ALANLIEB FOLKERULLMANN ASTRIDTRAUTWEIN AXELWISCHNAT RALFSCHNEIDER UDODREWES MARK-WILHELMERDELEN CHRISTOPHDAHMEN PETERFEUCHT DIETERPONTZEN ROLF
    • A01N43/16A01N43/40A01N47/06C07C69/67C07C69/757C07D309/32C07D311/96C07D405/12C07F9/655C07D311/26C07D409/10C07D405/10C07F9/40C07F9/09C07F9/32C07C69/675A01N57/00
    • Phenyl-substituted 5,6-dihydro-pyrone derivatives (I) are new. Dihydro-pyrone derivatives of formula (I) are new. dashed line = single or double bond, provided no 2 adjacent dashed lines are both double bonds; W = H, alkyl, alkenyl, alkynyl, halo, haloalkyl or alkoxy; X = halo, alkyl, alkoxy, alkenyl, alkynyl, haloalkyl, haloalkoxy or CN; or (all optionally substituted) phenyl, phenoxy, phenylthio, phenylalkoxy or phenylalkylthio; Y = H, alkyl, halo, alkoxy, alkenyl, alkynyl, optionally substituted aryl or optionally substituted heteroaryl; Z' = H, halo, alkyl, alkoxy, haloalkyl, haloalkoxy or CN; A = a bond; H; alkyl, alkenyl or alkoxyalkyl (all optionally substituted by halo); optionally substituted cycloalkyl or cycloalkylalkyl (optionally having at least one ring C replaced by a heteroatom); or aryl, aralkyl, heteroaryl or heteroaralkyl (all optionally substituted by halo, alkyl, haloalkyl, alkoxy, haloalkoxy, CN or NO2); B' = H or alkyl; or A + B' = group completing an optionally substituted, saturated or unsaturated ring, optionally containing at least one heteroatom; or B' + Q1 = alkanediyl (optionally substituted by optionally substituted alkyl or optionally substituted alkoxy and optionally having two non-adjacent C forming an optionally substituted ring); Q1 = H, OH, alkyl, alkoxy, alkoxyalkyl, alkylacyloxy (sic), optionally substituted cycloalkyl (in which one CH2 is optionally substituted by O or S) or optionally substituted phenyl; Q2 = H or alkyl; or Q1 + Q2 = group completing an optionally substituted ring, optionally containing at least one heteroatom; G = H, 1 equivalent of a metal atom, ammonium ion, -C(O)R1, -C(L)-MR2, -SO2R3, -P(L)R4R5 or -C(L)-NR6R7; L, M = O or S; R1 = alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl or alkylthioalkyl (all optionally substituted by halo); cycloalkyl (optionally substituted by halo, alkyl or alkoxy and optionally interrupted by at least one heteroatom); or phenyl, phenylalkyl, heteroaryl, phenoxyalkyl or heteroaryloxyalkyl (all optionally substituted); R2 = alkyl, alkenyl, alkoxyalkyl or polyalkoxyalkyl (all optionally substituted by halo); or cycloalkyl, phenyl or benzyl (all optionally substituted); R3-R5 = alkyl, alkoxy, mono- or dialkylamino, alkylthio, alkenylthio or cycloalkylthio (all optionally substituted by halo); or phenyl, benzyl, phenoxy or phenylthio (all optionally substituted); R6, R7 = H; alkyl, cycloalkyl, alkenyl, alkoxy or alkoxyalkyl (all optionally substituted by halo); or phenyl or benzyl (both optionally substituted); or NR6R7 = ring (optionally interrupted by O or S). Independent claims are included for: (1) the preparation of (I); and (2) new phenylacetate ester intermediates of formula (II). R8 = alkyl.
    • 10. 发明专利
    • New heterocyclic-substituted thiazole derivatives, useful as total or selective herbicides, insecticides, acaricides, nematocides, ectoparasiticides or antifouling agents
    • DE10029077A1
    • 2001-12-20
    • DE10029077
    • 2000-06-13
    • BAYER AG
    • FISCHER REINERBRETSCHNEIDER THOMASTRAUTWEIN AXELULLMANN ASTRIDDREWES MARK-WILHELMERDELEN CHRISTOPHDAHMEN PETERFEUCHT DIETERPONTZEN ROLF
    • C07D277/20A01N43/76A01N43/78A01N43/90A01N47/06C07D263/32C07D277/30C07D277/32C07D413/04C07D417/04C07D417/14C07D471/12C07D487/12C07D491/10C07D495/10
    • Pyrrolidinyl, furanyl or thienyl-substituted thiazole derivatives (I) are new. Pyrrolidinyl, furanyl or thienyl-substituted thiazole derivatives of formula (I) are new. X = H, halo, alkyl, alkoxy, alkenyloxy, NO2, CN or optionally substituted phenyl; Y = halo, alkyl, alkoxy, alkenyloxy, haloalkyl, haloalkenyloxy, alkylthio, alkylsulfinyl, alkylsulfonyl, optionally substituted phenyl or optionally substituted phenoxy; T = N-D, O or S; A = H, or alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl or alkylthioalkyl (all optionally substituted by halo), optionally substituted, saturated or unsaturated cycloalkyl (optionally having at least one ring C replaced by a heteroatom), or aryl, aralkyl or heteroaryl (all optionally substituted by halo, alkyl, haloalkyl, alkoxy, haloalkoxy, CN or NO2); B' = H, alkyl or alkoxyalkyl; or A + B' = group completing an optionally substituted, saturated or unsaturated ring, optionally containing at least one heteroatom; D = H, or alkyl, alkenyl, alkynyl, alkoxyalkyl, polyalkoxyalkyl, alkylthioalkyl, saturated or unsaturated cycloalkyl (optionally having at least one ring C replaced by a heteroatom), aryl, aralkyl or heteroaryl; or A + D = optionally substituted group completing an optionally substituted, saturated or unsaturated ring, optionally containing at least one heteroatom; G = H, 1 equivalent of a metal atom, ammonium ion, -C(O)R1, -C(L)-MR2, -SO2R3, -P(L)R4R5 or -C(L)-NR6R7; L, M = O or S; R1 = alkyl, alkenyl, alkoxyalkyl, polyalkoxyalkyl or alkylthioalkyl (all optionally substituted by halo), cycloalkyl (optionally substituted by halo, alkyl or alkoxy and optionally interrupted by at least one heteroatom); or phenyl, phenylalkyl, heteroaryl, phenoxyalkyl or heteroaryloxyalkyl (all optionally substituted); R2 = alkyl, alkenyl, alkoxyalkyl or polyalkoxyalkyl (all optionally substituted by halo); or cycloalkyl, phenyl or benzyl (all optionally substituted); R3 = alkyl, haloalkyl, optionally substituted phenyl or optionally substituted benzyl; R4, R5 = alkyl, alkoxy, mono- or dialkylamino, alkylthio, alkenylthio or cycloalkylthio (all optionally substituted by halo), or phenyl, benzyl, phenoxy or phenylthio; and R6, R7 = H, or alkyl, cycloalkyl, alkenyl, alkoxy or alkoxyalkyl (all optionally substituted by halo); or phenyl or benzyl (both optionally substituted); or NR6R7 = ring (optionally interrupted by O or S). Independent claims are also included for the following: (1) preparation of (I); and (2) new intermediates of formula (II; COOR8 replaced by COOH or CN), (III) and (IV). R8 = alkyl; and W1 = H, halo, alkyl or alkoxy.