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1. 发明申请

WO2009089213A2 'SYSTEM AND METHOD FOR DETECTING OCCLUSION USING FLOW SENSOR OUTPUT' 审中-公开
标题翻译： “使用流量传感器输出检测信息的系统和方法”
公开(公告)号：WO2009089213A2
公开(公告)日：2009-07-16
申请号：PCT/US2009/030210
申请日：2009-01-06
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A. , DELCASTILLO, Jorge , YARDIMCI, Atif
发明人： DELCASTILLO, Jorge , YARDIMCI, Atif
IPC分类号： A61M5/14
CPC分类号： A61M5/14212 , A61M5/16831 , A61M2205/3331 , A61M2205/3334
摘要： A method and system for detecting an inclusion within an infusion system. The method includes monitoring an output signal of a flowrate sensor as fluid flows through an infusion system. The output signal is then converted with a noise reduction filter to obtain a filtered output signal. The filtered output signal is compared to a threshold value and an alarm is activated if the filtered output signal falls below a desired threshold, thereby indicating an occlusion within the infusion system.
摘要翻译：一种用于检测输注系统内的夹杂物的方法和系统。该方法包括当流体流过输注系统时监测流量传感器的输出信号。然后用噪声降低滤波器转换输出信号以获得滤波的输出信号。将滤波后的输出信号与阈值进行比较，并且如果滤波的输出信号低于期望的阈值，则报警被激活，从而指示输注系统内的闭塞。

2. 发明申请

WO2005044418A3 FLOW-THROUGH REMOVAL DEVICE AND SYSTEM USING SUCH DEVICE 审中-公开
公开(公告)号：WO2005044418A3
公开(公告)日：2005-05-19
申请号：PCT/US2004/029637
申请日：2004-09-08
申请人： BAXTER INTERNATIONAL INC. , REITZ, Douglas W. , ARIAGNO, Scott , SHETH, Mihir , YARDIMCI, Atif , CLARKE, Robert A. , PENNINGTON, David W. , PRISCO, Michael R. , CHIM, Edwin , PAULEY, Robin , SANDFORD, Craig , SITES, Arch
发明人： REITZ, Douglas W. , ARIAGNO, Scott , SHETH, Mihir , YARDIMCI, Atif , CLARKE, Robert A. , PENNINGTON, David W. , PRISCO, Michael R. , CHIM, Edwin , PAULEY, Robin , SANDFORD, Craig , SITES, Arch
IPC分类号： B01D29/05
摘要： Flow-through systems for processing biological fluid are disclosed. The flow-through systems include a removal device in the flow path for removing unwanted compounds and agents. The removal device includes a removal media contained within a housing made of two separate portions sealed together. The housing is maintained in a substantially vertical disposition, thereby ensuring substantially uniform and complete exposure of the fluid to the media.

3. 发明申请

WO2003039375A3 LAPAROSCOPIC SPRAY DEVICE AND METHOD OF USE 审中-公开
公开(公告)号：WO2003039375A3
公开(公告)日：2003-05-15
申请号：PCT/US2002/031985
申请日：2002-10-07
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE S.A.
发明人： SPERO, Richard , YARDIMCI, Atif , EPSTEIN, Gordon
IPC分类号： A61B17/00
摘要： A laparoscopic spray device for selectively applying a multiple component material dispensed from a multiple component material applicator to a surgical site in vivo is disclosed. The device comprises an interface member capable of engaging a multiple component applicator, a body having at least two lumens therein, and a detachable spray tip in fluid communication with the body. The detachable spray tip includes a mixing chamber having at least one flexible mixing member positioned therein which is capable of creating a turbulent flow within a mixing chamber. In addition, the at least one mixing member prevents a back flow of material from the mixing chamber to the at least two lumens. The present invention is particularly useful in remotely applying multiple component tissue adhesives to an internal incision.

4. 发明公开

EP1434524A2 LAPAROSCOPIC SPRAY DEVICE AND METHOD OF USE 审中-公开
标题翻译：腹腔镜喷雾器和程序
公开(公告)号：EP1434524A2
公开(公告)日：2004-07-07
申请号：EP02802779.5
申请日：2002-10-07
申请人： Baxter International Inc. , Baxter Healthcare S.A.
发明人： SPERO, Richard , YARDIMCI, Atif , EPSTEIN, Gordon
IPC分类号： A61B17/00
CPC分类号： B05C17/00593 , A61B17/00491 , A61B2017/00495 , B05C17/00516
摘要： A laparoscopic spray device for selectively applying a multiple component material dispensed from a multiple component material applicator to a surgical site in vivo is disclosed. The device comprises an interface member capable of engaging a multiple component applicator, a body having at least two lumens therein, and a detachable spray tip in fluid communication with the body. The detachable spray tip includes a mixing chamber having at least one flexible mixing member positioned therein which is capable of creating a turbulent flow within a mixing chamber. In addition, the at least one mixing member prevents a back flow of material from the mixing chamber to the at least two lumens. The present invention is particularly useful in remotely applying multiple component tissue adhesives to an internal incision.

5. 发明申请

WO2004000394A1 FLUID DELIVERY SYSTEM WITH CLOSED-LOOP FLOW CONTROL AND METHOD 审中-公开
标题翻译：具有闭环流量控制和方法的流体输送系统
公开(公告)号：WO2004000394A1
公开(公告)日：2003-12-31
申请号：PCT/US2003/017740
申请日：2003-06-05
申请人： BAXTER INTERNATIONAL INC.
发明人： JACOBSON, James, D. , BUI, Tuan , GARCHOW, Stephen, R. , YARDIMCI, Atif , SLEPICKA, James, S.
IPC分类号： A61M5/172
CPC分类号： A61M5/16886 , A61M5/14236 , A61M5/172 , A61M2205/0244 , A61M2205/0294 , G05D7/0676
摘要： A fluid delivery system having a closed-loop control process for delivering a medical fluid to a patient (120,220). A fluid infusion system includes a pump (100,208) for delivering a fluid to a patient via an administration tube (122,206). A flow sensor (126,212) associated with the administration tube provides an indication of the actual flow rate (224) of fluid in the administration tube. Such a flow sensor may comprise a positive displacement flow sensor (402) constructed using micro-fabrication and/or micro-molding techniques. A reader (230) reads the actual flow rate signal and provides an indication (234) to a controller (232) for controlling the pump. The flow rate information can also be used for providing status information, such as the existence of a blockage (250) in the fluid delivery system.
摘要翻译：一种流体输送系统，具有用于将医用流体输送到患者的闭环控制过程（120,220）。流体输注系统包括用于经由给药管（122,206）将流体输送给患者的泵（100,208）。与给药管相关联的流量传感器（126,212）提供了给药管中流体的实际流速（224）的指示。这种流量传感器可以包括使用微制造和/或微型成型技术构造的正排量流量传感器（402）。读取器（230）读取实际流量信号，并向用于控制泵的控制器（232）提供指示（234）。流量信息还可以用于提供状态信息，例如在流体输送系统中存在阻塞（250）。

6. 发明申请

WO2004058046A2 FLUID TREATMENT METHOD, APPARATUS AND SYSTEM 审中-公开
标题翻译：流体处理方法，装置和系统
公开(公告)号：WO2004058046A2
公开(公告)日：2004-07-15
申请号：PCT/US2003/039973
申请日：2003-12-16
申请人： BAXTER INTERNATIONAL INC.
发明人： JOHNSON, Kenneth, M. , DAHAN, Meir , SHADMAN, Sohail , JONES, Mark, B. , WEST, Richard, L. , LO, Ying-Cheng , MUI, Tat, Chi , AKONUR, Alp , YARDIMCI, Atif , DAVIS, Shawn , ZHIZHIN, Nikolay , KILLE, Eric, J. , WESTBERG, Tom , LABONTE, Judith , JOHNSTON, John, F. , OTTINO, Julio , LEIBSON, Abraham , PENNINGTON, David, W. , PAWLAK, Kenneth, E. , MORIARITY, Julie, A. , SLEPICKA, Jane, S.
IPC分类号： A61B
CPC分类号： A61M1/3692 , A61M1/02 , A61M1/0218 , A61M1/1006 , A61M1/1039 , A61M1/1081 , A61M1/3679 , A61M1/3687 , A61M39/221 , A61M2039/222 , A61M2205/12 , A61M2206/22
摘要： Treatment apparatus, system and method are disclosed for treating a biological fluid, such as blood or blood components. The treatment may include but isnot limited to inactivation of pathogens in red cell concentrate. The system may include a disposable fluid circuit assembly and a reusable controller that controls flow through the fluid circuit for reconstituting, if necessary, a treating agent, combining the treating agent with a biological fluid and mixing the agent and biological fluid. An optional quenching agent may also be used.
摘要翻译：公开了用于处理诸如血液或血液成分的生物流体的处理装置，系统和方法。治疗可能包括但不限于红细胞浓缩物中病原体的灭活。该系统可以包括一次性流体回路组件和可重复使用的控制器，其控制通过流体回路的流动，以便如果需要，重组处理剂，将处理剂与生物流体混合并混合该试剂和生物流体。也可以使用任选的淬火剂。

7. 发明申请

WO2017142693A1 AIRTRAP, SYSTEM AND METHOD FOR REMOVING MICROBUBBLES FROM A FLUID STREAM 审中-公开
标题翻译： AIRTRAP，系统和从流体流中去除微泡的方法
公开(公告)号：WO2017142693A1
公开(公告)日：2017-08-24
申请号：PCT/US2017/015322
申请日：2017-01-27
申请人： BAXTER INTERNATIONAL INC. , BAXTER HEALTHCARE SA
发明人： PERRY, Mark , DELCASTILLO, Jorge , MULLER, Matthew , CORRALES, Carlos , YARDIMCI, Atif , LAIRD, James
IPC分类号： A61M1/36 , A61M5/36 , B01D19/00
CPC分类号： A61M1/1658 , A61M1/28 , A61M1/3486 , A61M1/3627 , A61M1/3638 , A61M1/3679 , A61M5/36 , A61M5/385 , A61M2205/123 , A61M2205/7536 , A61M2206/16 , B01D19/0057
摘要： An airtrap for a medical or physiological fluid in one embodiment includes a conical housing having a radius that increases from its top to its bottom when the housing is positioned for operation; a medical or physiological fluid inlet located at an upper portion of the conical housing; a medical or physiological fluid outlet located at a lower portion of the conical housing, the inlet and the outlet positioned and arranged so that medical or physiological fluid spirals in an increasing arc around an inside of the conical housing downwardly from the inlet to the outlet; and a gas collection area located at an upper portion of the conical housing. In another embodiment, the airtrap is shaped like a seahorse having a head section and a tail section. Any of the airtraps herein may be used for example in blood sets, peritoneal dialysis cassette tubing, and drug delivery sets.
摘要翻译：在一个实施例中，用于医疗或生理流体的空气囊包括圆锥形壳体，当壳体被定位用于操作时，圆锥形壳体具有从其顶部到其底部增大的圆锥形壳体; 位于圆锥形壳体的上部的医疗或生理流体入口; 位于圆锥形壳体下部的医疗或生理流体出口，入口和出口被定位和布置成使得医疗或生理流体围绕圆锥形壳体内部从入口到出口向下以增加的弧度螺旋形地旋转; 以及位于圆锥形壳体上部的气体收集区域。在另一个实施例中，空气囊形状像具有头部和尾部的海马。本文中的任何气室可用于例如血液组，腹膜透析盒管和药物递送组。

8. 发明授权

EP3416702B1 AIRTRAP AND SYSTEMS FOR REMOVING MICROBUBBLES FROM A FLUID STREAM 有权
公开(公告)号：EP3416702B1
公开(公告)日：2020-03-11
申请号：EP17706009.2
申请日：2017-01-27
申请人： Baxter International Inc. , Baxter Healthcare SA
发明人： PERRY, Mark , DELCASTILLO, Jorge , MULLER, Matthew , CORRALES, Carlos , YARDIMCI, Atif , LAIRD, James
IPC分类号： A61M1/36 , A61M5/36 , B01D19/00

9. 发明授权

EP1324787B1 PERITONEAL DIALYSIS CATHETERS 有权
标题翻译：导管腹膜透析
公开(公告)号：EP1324787B1
公开(公告)日：2007-02-14
申请号：EP01979903.0
申请日：2001-09-28
申请人： Baxter International Inc.
发明人： RUDDELL, Scott , YARDIMCI, Atif , DEL CASTILLO, Jorge
IPC分类号： A61M1/28
CPC分类号： A61M1/285 , A61M1/284 , A61M25/0041 , A61M25/04
摘要： A catheter suitable for use in performing peritoneal dialysis. The catheter is a dual lumen catheter which allows for continuous flow peritoneal dialysis. Dialysate flows through the catheter into the patient via one lumen and simultaneously flows through the catheter out of the patient via the second lumen. The dual lumen dialysis catheter has a flexible tube which has an implantable portion extending from an external patient portion. Both of the lumens have openings in the external patient portion for connecting to a supply and drain of dialysate, respectively. The implantable portion has a preformed curved segment which has an outlet for the first lumen to flow dialysate into the patient's peritoneal cavity. The implantable portion has an opening for the second lumen at the distal end to flow dialysate out of the peritoneal cavity and removal from the patient. The catheter facilitates mixing of fresh and spent dialysate inside the pentoneal cavity by inflowing fresh dialysate into the cavity at a location substantially separated from the cavity outflow location, and by directing the inflow of dialysate into the cavity opposite the cavity outflow location.

10. 发明公开

EP1682245A2 FLOW-THROUGH REMOVAL DEVICE AND SYSTEM USING SUCH DEVICE 有权转让
标题翻译：流动距离装置和这种装置使用的系统
公开(公告)号：EP1682245A2
公开(公告)日：2006-07-26
申请号：EP04816859.5
申请日：2004-09-08
申请人： Baxter International Inc.
发明人： REITZ, Douglas W. , ARIAGNO, Scott , SHETH, Mihir , YARDIMCI, Atif , CLARKE, Robert A. , PENNINGTON, David W. , PRISCO, Michael R. , CHIM, Edwin , PAULEY, Robin , SANDFORD, Craig , SITES, Arch
IPC分类号： B01D29/05 , B01D35/30
CPC分类号： A61M1/3633 , A61M1/0222 , A61M1/3687 , A61M2205/75
摘要： Flow-through systems for processing biological fluid are disclosed. The flow-through systems include a removal device in the flow path for removing unwanted compounds and agents. The removal device includes a removal media contained within a housing made of two separate portions sealed together. The housing is maintained in a substantially vertical disposition, thereby ensuring substantially uniform and complete exposure of the fluid to the media.

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