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1. 发明申请

WO2010060811A3 HYDROPHOBINS AS SURFACE ACTIVE PROTEINS AS EXCIPIENTS IN SOLID PHARMACEUTICAL FORMULATIONS 审中-公开
标题翻译：作为表面活性蛋白的水解物作为固体药物制剂中的主要成分
公开(公告)号：WO2010060811A3
公开(公告)日：2010-10-21
申请号：PCT/EP2009065100
申请日：2009-11-13
申请人： BASF SE , BUTHE ANDREAS , HAFNER ANDREAS , KAUFMANN FRANZ , GABOR ESTHER , MEURER GUIDO , ECK JUERGEN , BRADLEY GORDON
发明人： BUTHE ANDREAS , HAFNER ANDREAS , KAUFMANN FRANZ , GABOR ESTHER , MEURER GUIDO , ECK JUERGEN , BRADLEY GORDON
IPC分类号： A61K9/20 , A61K9/00 , A61K9/28 , C07K14/37
CPC分类号： A61K9/4891 , A61K9/0065 , A61K9/2063 , A61K9/2095 , A61K9/2873 , C07K14/37
摘要： The invention relates to a use of surface active hydrophobins for applications in pharmaceutical technology, in particular as excipients for galenic use. Provided is a method for either admixture of hydrophobins to galenic compositions or for treating the surface of pharmaceutical forms with a hydrophobin-containing solution to modify the pharmaceutical properties of the galenic form. In a preferred embodiment of the invention hydrophobins are used to improve the properties of a pharmaceutical composition, e. g. to act as a surfactant or to increase resistance to disintegration of the galenic forms to achieve a retarded drug release. The galenic form to be modified by the use of surface active proteins as excipients can be capsules, tablets, pills, microparticles, vesicles, and suppositories, although further galenic forms are envisioned. The surface active proteins used for the purpose of present invention can either be isolated from their respective natural source or prepared by recombinant techniques and expression in a suitable host.
摘要翻译：本发明涉及用于制药技术中的表面活性疏水蛋白的用途，特别是作为涂覆液使用的赋形剂。提供了将疏水蛋白与盖仑组合物混合或用含疏水蛋白的溶液处理药物形式的表面以改变盖仑膜形式的药物性质的方法。在本发明的优选实施方案中，疏水蛋白用于改善药物组合物的性质，例如， G。作为表面活性剂或增加耐受霜冻形式的崩解以实现延缓药物释放。通过使用表面活性蛋白质作为赋形剂来修饰的盖仑形式可以是胶囊，片剂，丸剂，微粒，囊泡和栓剂，尽管可以预见到更多的盖仑制剂形式。用于本发明目的的表面活性蛋白质可以从它们各自的天然来源中分离或者通过重组技术制备并在合适的宿主中表达。

2. 发明申请

WO02098289A8 APPARATUS AND METHOD FOR TESTING VISUAL RESPONSE 审中-公开
标题翻译：用于测试视觉响应的装置和方法
公开(公告)号：WO02098289A8
公开(公告)日：2006-12-07
申请号：PCT/GB0202261
申请日：2002-05-29
申请人： BRIGANTIA SOFTWARE LTD , BRADLEY GORDON
发明人： BRADLEY GORDON
IPC分类号： A61B5/0484
CPC分类号： A61B5/04842
摘要： Apparatus and method for testing the visual response of a patient is disclosed. The apparatus comprises image generation means (16), image presentation means (12), and detection means (13,14). The image generation means (16) and image presentation means (12) are arranged, in use, to generate and present an image before an eye of the patient at variable predetermined intensity levels. The detection means (13,14) is arranged under the control of a controller (11) to detect a stimulus response to the presented image occurring in the brain of the patient and to display an image of the response of the patient's eye on a monitor (15).
摘要翻译：公开了用于测试患者的视觉反应的装置和方法。该装置包括图像产生装置（16），图像呈现装置（12）和检测装置（13,14）。在使用中，图像生成装置（16）和图像呈现装置（12）被布置为在可变的预定强度水平下生成并呈现患者的眼睛之前的图像。检测装置（13,14）被布置在控制器（11）的控制下，以检测对患者的大脑中出现的所呈现的图像的刺激响应，并在监视器上显示患者眼睛的响应的图像（15）。

3. 发明申请

WO2009077349A1 PROCESS FOR THE PREPARATION OF SEMICONDUCTING LAYERS 审中-公开
标题翻译：制备半导体层的过程
公开(公告)号：WO2009077349A1
公开(公告)日：2009-06-25
申请号：PCT/EP2008066839
申请日：2008-12-05
申请人： CIBA HOLDING INC , BRADLEY GORDON , BUERGI LUKAS , BIENEWALD FRANK
发明人： BRADLEY GORDON , BUERGI LUKAS , BIENEWALD FRANK
IPC分类号： H01L51/10
CPC分类号： H01L51/0545 , B82Y20/00 , B82Y30/00 , H01L51/0004 , H01L51/0558 , H01L2251/5369 , Y02E10/549 , Y02P70/521
摘要： A convenient way for preparing thin layers of organic semiconducting materials comprises application or deposition of particles of a semiconducting material containing an organic semiconductor on a suitable surface, and converting these particles into a semiconducting layer on a substrate by application of pressure and optionally elevated temperatures.
摘要翻译：用于制备有机半导体材料薄层的便利方式包括在合适的表面上施加或沉积含有有机半导体的半导体材料颗粒，并且通过施加压力和任选升高的温度将这些颗粒转变成衬底上的半导体层。

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