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    • 1. 发明申请
    • ANTIFUNGAL PAENIBACILLUS STRAINS, FUSARICIDIN-TYPE COMPOUNDS, AND THEIR USE
    • 抗真菌菌株,福萨西汀型化合物及其用途
    • WO2016020371A1
    • 2016-02-11
    • PCT/EP2015/067925
    • 2015-08-04
    • BASF SE
    • SIEPE, IsabellaBRÜSER, HeikeKLAPPACH, KristinSCHNEIDER, Karl-HeinrichSPRÖTE, PetraHAGE, KerstinBLANZ, BirgitTHINES, EckhardANTELO, LuisSANDJO, Louis PergaudOPATZ, Till
    • C12N1/20
    • A01N63/02C07K14/195C12N1/20
    • The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus , originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus . The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens. The present invention also relates to a method of controlling or suppressing plant pathogens or preventing plant pathogen infections by applying such composition. The present invention also relates to novel fusaricidin-type compounds which are metabolites produced by the strains of the present invention.
    • 本发明涉及新型分离的细菌菌株,其是Paenibacillus属的成员,其最初从土壤中分离并显示出对广泛病原体的拮抗活性并且能够产生抗微生物代谢物。 发现菌株Lu16774和Lu17007属于一种新型亚种,称为多粘菌芽孢杆菌(Paenibacillus polymyxa ssp)。 植物乳杆菌,而菌株Lu17015属于被称为附生芽孢杆菌的新型物种。 本发明还涉及微生物农药组合物,其包含至少一种这样的新细菌菌株,全培养肉汤或无细胞提取物或其部分或至少一种代谢物,和/或至少一种所述 具有各种细菌菌株或全培养肉汤,无细胞提取物,其突变体的级分和/或代谢物的所有鉴定特征的新菌株显示对植物病原体的拮抗活性。 本发明还涉及通过应用这种组合物来控制或抑制植物病原体或防止植物病原体感染的方法。 本发明还涉及作为本发明菌株产生的代谢产物的新颖的枯草菌素型化合物。
    • 5. 发明公开
    • ANTIFUNGAL PAENIBACILLUS STRAINS, FUSARICIDIN-TYPE COMPOUNDS, AND THEIR USE
    • 抗真菌药物复方制剂,复方制剂及其应用
    • EP3194566A1
    • 2017-07-26
    • EP15744949.7
    • 2015-08-04
    • BASF SE
    • SIEPE, IsabellaBRÜSER, HeikeKLAPPACH, KristinSCHNEIDER, Karl-HeinrichSPRÖTE, PetraHAGE, KerstinBLANZ, BirgitTHINES, EckhardANTELO, LuisSANDJO, Louis PergaudOPATZ, Till
    • C12N1/20
    • A01N63/02C07K14/195C12N1/20
    • The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens. The present invention also relates to a method of controlling or suppressing plant pathogens or preventing plant pathogen infections by applying such composition. The present invention also relates to novel fusaricidin-type compounds which are metabolites produced by the strains of the present invention.
    • 本发明涉及新的分离的细菌菌株,它们是类芽孢杆菌属成员,最初是从土壤中分离出来的,并显示出对多种病原体的拮抗活性并能够产生抗微生物代谢物。 发现菌株Lu16774和Lu17007属于一个新亚种Paenibacillus polymyxa ssp。 植物乳杆菌,而菌株Lu17015属于被认为属于类芽孢杆菌属的新种。 本发明还涉及包含至少一种这样的新型细菌菌株,全培养肉汤或无细胞提取物或其部分或其至少一种代谢物,和/或所述至少一种所述突变体的微生物农药组合物 具有对植物病原体显示拮抗活性的相应细菌菌株或全培养肉汤,无细胞提取物,其突变体的部分和/或代谢物的全部鉴定特征的新型细菌菌株。 本发明还涉及通过施用这种组合物来控制或抑制植物病原体或预防植物病原体感染的方法。 本发明还涉及由本发明的菌株产生的代谢物的新型镰孢菌素型化合物。