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    • 3. 发明申请
    • PROCESS FOR PREPARING HYDROGEL SKIN ADHESIVE UNDER LOW OXYGEN CONDITIONS
    • 在低氧条件下制备羟丙基胶粘剂的方法
    • WO2005054306A1
    • 2005-06-16
    • PCT/EP2004/013146
    • 2004-11-19
    • BASF AktiengesellschaftGÖRTH, Felix ChristianWEIDL, Christian HubertFRENZ, VolkerSTEPHAN, Oskar
    • GÖRTH, Felix ChristianWEIDL, Christian HubertFRENZ, VolkerSTEPHAN, Oskar
    • C08F2/01
    • C08F20/04A61L26/008C08F2/10
    • Abstract The present invention relates to a process of making polymerized hydrogels, in particular hydrogel adhesives which e.g. are capable of attaching to mammalian skin and can be used in various personal care products, such as waste-management articles, cosmetic and medical devices and a variety of functional articles to be worn by a human. The process described herein is characterized by influencing the adhesiveness by varying the oxygen content of the atmosphere present during the polymerization. Utilizing this method it is possible to influence one performance parameter (adhesiveness) independently from the others (e.g. rheology behaviour). This opens ways to a more easy and more flexible production of such hydrogels. In addition it is possible to obtain hydrogels with a combination of rheology and adhesiveness properties that were not or not so easily obtainable by conventional means. Lowering the oxygen content of the atmosphere at the polymerization zone also gives an additional benefit in lowering the amount of residual monomer(s).
    • 摘要本发明涉及一种制备聚合水凝胶的方法,特别是水凝胶粘合剂, 能够附着于哺乳动物皮肤,并可用于各种个人护理产品,例如废物处理用品,化妆品和医疗装置以及人类所穿的各种功能性物品。 本文所述的方法的特征在于通过改变聚合期间存在的气氛的氧含量来影响粘附性。 利用该方法,可以独立于其它方式影响一个性能参数(粘合性)(例如流变行为)。 这开创了一种更容易和更灵活地生产这种水凝胶的方法。 此外,可以获得具有通过常规方法不容易获得的流变性和粘合性的组合的水凝胶。 在聚合区域降低气氛的氧含量也可以降低残留单体的量带来额外的益处。
    • 4. 发明申请
    • POLYMERIZED HYDROGEL ADHESIVES WITH HIGH LEVELS OF MONOMER UNITS IN SALT FORM
    • 高分子单体单体盐酸聚合胶粘剂
    • WO2004029174A1
    • 2004-04-08
    • PCT/EP2003/010380
    • 2003-09-18
    • BASF AKTIENGESELLSCHAFTWEIDL, Christian, HubertGÖRTH, Felix, ChristianFRENZ, Volker
    • WEIDL, Christian, HubertGÖRTH, Felix, ChristianFRENZ, Volker
    • C09J201/08
    • A61L15/58A61L15/60C08L33/02
    • The present invention relates to hydrogel adhesives which are capable of attaching to mammalian skin, exhibit excellent attachment and painless removal properties, and which show excellent stability upon storage at room temperature or even at elevated temperatures and for longer periods of time. The adhesive hydrogel described in the present invention can be used as body adhesive in products for e.g. personal care, medical devices, beauty care and a variety of functional articles to be worn by a human. The hydrogel adhesive of the invention comprises 10-60 wt.% of a cross-linked hydrophilic polymer, 5-80 wt.% of a water-soluble non-ionic humectant, and from about 10-85 wt.% water, wherein the hydrophilic polymer comprises at least 80 mole % of one or more weak-acid monomer units having a pKa above 3, the weak-acid monomer being more than 60 mole % in its salt form, the level of monomer in acid form in said hydrophilic polymer not exceeding 50 mole % of all monomer units and the hydrogel adhesive having a peel strength on PET of 0.3 to 5.0 N/cm and a stability index measured after 14 days SIx14 below 0.50, preferably below 0.20, most preferably below 0.10.
    • 本发明涉及能够附着于哺乳动物皮肤的水凝胶粘合剂,表现出优异的附着性和无痛去除性,并且在室温或甚至在升高的温度下保存较长时间后显示出极好的稳定性。 本发明中描述的粘合剂水凝胶可以用作例如产品中的身体粘合剂。 个人护理,医疗器械,美容护理和人体穿戴的各种功能性物品。 本发明的水凝胶粘合剂包含10-60重量%的交联亲水性聚合物,5-80重量%的水溶性非离子保湿剂和约10-85重量%的水,其中 亲水性聚合物包含至少80摩尔%的一种或多种pKa高于3的弱酸单体单元,弱酸单体的盐形式大于60摩尔%,所述亲水聚合物中酸形式的单体含量 不超过所有单体单元的50摩尔%,PET上的剥离强度为0.3-5.0N / cm的水凝胶粘合剂和在14天后测量的稳定指数SIx14低于0.50,优选低于0.20,最优选低于0.10。