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    • 2. 发明专利
    • DE69913104T2
    • 2004-06-17
    • DE69913104
    • 1999-02-09
    • BASF AG
    • PFRENGLE WALDEMARPEES KLAUS-JUERGENALBERT GUIDO
    • A01N43/00A01N43/90C07D487/04
    • A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.
    • 4. 发明专利
    • DK1054888T3
    • 2004-04-05
    • DK99905905
    • 1999-02-09
    • BASF AG
    • PFRENGLE WALDEMARPEES KLAUS-JUERGENALBERT GUIDO
    • A01N43/00A01N43/90C07D487/04
    • A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.
    • 7. 发明专利
    • AT255110T
    • 2003-12-15
    • AT99905905
    • 1999-02-09
    • BASF AG
    • PFRENGLE WALDEMARPEES KLAUS-JUERGENALBERT GUIDO
    • A01N43/00A01N43/90C07D487/04C07D249/00C07D239/00
    • A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.A process and intermediates for the preparation of triazolopyrimidine compounds of formula I wherein R , X, L , L , L , L and L are as defined in the description, which comprises reacting alkyl 2-aryl-3-alkyl-3-oxopropionates of formula IV wherein R and L , L , L , L and L are as defined for formula I and R' represents an optionally substituted alkyl group, a) with 2-amino-Ä1,3,4Ü-triazole, and treating the resulting 5-hydroxytriazolopyrimidines of formula I, wherein X represents a hydroxy group, with a halogenating agent, and b) optionally treating the resulting 5-hydroxytriazolopyrimidines with an alcohol or a thioalkohol in the presence of a base, or with a metal amide, a metal alkyl amide or a metal dialkylamide, or a metal cyanide.