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    • 4. 发明申请
    • Barorflex stimulation system to reduce hypertension
    • Barorflex刺激系统降低高血压
    • US20050149128A1
    • 2005-07-07
    • US10746134
    • 2003-12-24
    • Ronald HeilAvram ScheinerImad Libbus
    • Ronald HeilAvram ScheinerImad Libbus
    • A61N1/36A61N1/362A61N1/365
    • A61N1/36117A61N1/3627A61N1/36564
    • Various aspects of the present subject matter provide an implantable medical device. In various embodiments, the device comprises a pulse generator, a lead, a sensor, and a controller. The pulse generator generates a baroreflex stimulation signal as part of a baroreflex therapy. The lead is adapted to be electrically connected to the pulse generator and to be intravascularly fed into a heart. The lead includes an electrode to be positioned in or proximate to the heart to deliver the baroreflex signal to a baroreceptor region in or proximate to the heart. The sensor senses a physiological parameter regarding an efficacy of the baroreflex therapy and provides a signal indicative of the efficacy. The controller is connected to the pulse generator to control the baroreflex stimulation signal and to the sensor to receive the signal indicative of the efficacy of the baroreflex therapy. Other aspects are provided herein.
    • 本主题的各个方面提供可植入医疗装置。 在各种实施例中,该装置包括脉冲发生器,引线,传感器和控制器。 脉冲发生器产生压力反射刺激信号作为压力反射治疗的一部分。 引线适于电连接到脉冲发生器并且被血管内馈送到心脏中。 引线包括位于心脏中或靠近心脏的电极以将压力反射信号传递到心脏中或心脏附近的压力感受器区域。 传感器感测关于压力反射治疗的功效的生理参数,并提供指示功效的信号。 控制器连接到脉冲发生器以控制压力反射刺激信号和传感器以接收指示压力反射治疗功效的信号。 本文提供了其他方面。