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1. 发明申请

US20110129816A1 DEVICE FOR DETECTION OF INFLUENZA VIRUS 审中-公开
标题翻译：用于检测流感病毒的装置
公开(公告)号：US20110129816A1
公开(公告)日：2011-06-02
申请号：US12996340
申请日：2009-06-05
申请人： Atsushi Muraguchi , Hiroyuki Kishi , Tatsuhiko Ozawa , Mamoru Ikemoto , Hitoshi Ono , Kazuki Morita , Koji Uzawa
发明人： Atsushi Muraguchi , Hiroyuki Kishi , Tatsuhiko Ozawa , Mamoru Ikemoto , Hitoshi Ono , Kazuki Morita , Koji Uzawa
IPC分类号： C12Q1/70 , C12M1/34 , C07K16/10
CPC分类号： C07K16/1018 , C07K2317/21 , C07K2317/33 , C07K2319/61 , G01N33/558 , G01N33/56983 , G01N2333/11
摘要： A device for detecting or quantifying influenza viruses in a sample, which comprises a detection region having a human anti-influenza virus nucleoprotein antibody immobilized onto a support, a sample supply region, and a sample-migrating region; and a kit for detecting or quantifying influenza viruses, which comprises a solid phase in which a human anti-influenza virus nucleoprotein antibody is fixed onto a carrier.
摘要翻译：用于检测或定量样品中的流感病毒的装置，其包含检测区域，其具有固定在载体上的人抗流感病毒核蛋白抗体，样品供应区域和样品迁移区域; 以及用于检测或定量流感病毒的试剂盒，其包含将抗人流感病毒核蛋白抗体固定在载体上的固相。

2. 发明申请

US20130273575A1 Method for Assaying Fibroblast Growth Factor-23 and Assay Reagent 有权
标题翻译：测定成纤维细胞生长因子-23和测定试剂的方法
公开(公告)号：US20130273575A1
公开(公告)日：2013-10-17
申请号：US13819398
申请日：2011-08-31
申请人： Koji Uzawa , Emiko Suzuki , Kazuyuki Ikeda , Kazuki Morita
发明人： Koji Uzawa , Emiko Suzuki , Kazuyuki Ikeda , Kazuki Morita
IPC分类号： G01N33/74
摘要： A method for measuring fibroblast growth factor-23 (FGF-23) in a sample, which comprise the following steps: (1) reacting, in an aqueous medium, FGF-23 in a sample with magnetic particles, a first antibody or a fragment thereof which binds to FGF-23, and a second antibody or a fragment thereof which binds to FGF-23, to form on the magnetic particles an immunocomplex comprising the first antibody or a fragment thereof which binds to FGF-23, FGF-23, and the second antibody or a fragment thereof which binds to FGF-23; (2) collecting the magnetic particles in the reaction mixture after step (1) by magnetic force, and separating the magnetic particles collected by magnetic force from the other components; and (3) measuring the immunocomplex on the magnetic particles separated in step (2). The present invention provides a method for measuring FGF-23 in a sample, which have a high sensitivity and have a wide measurement range.
摘要翻译： 1，一种测定样品中成纤维细胞生长因子-23（FGF-23）的方法，包括以下步骤：（1）在水性介质中使样品中的FGF-23与磁性颗粒，第一抗体或片段其与FGF-23结合，以及结合FGF-23的第二抗体或其片段，在磁性颗粒上形成包含与FGF-23，FGF-23结合的第一抗体或其片段的免疫复合物，和与FGF-23结合的第二抗体或其片段; （2）通过磁力在步骤（1）之后收集反应混合物中的磁性颗粒，并将由磁力收集的磁性颗粒与其它组分分离; 和（3）测量在步骤（2）中分离的磁性颗粒上的免疫复合物。本发明提供一种用于测量样品中的FGF-23的方法，其具有高灵敏度并且具有宽的测量范围。

3. 发明授权

US10422796B2 Method for measuring fibroblast growth factor-23 and reagent therefor 有权
公开(公告)号：US10422796B2
公开(公告)日：2019-09-24
申请号：US13819398
申请日：2011-08-31
申请人： Koji Uzawa , Emiko Suzuki , Kazuyuki Ikeda , Kazuki Morita
发明人： Koji Uzawa , Emiko Suzuki , Kazuyuki Ikeda , Kazuki Morita
IPC分类号： G01N33/543 , G01N33/538 , G01N33/74
摘要： A method for measuring fibroblast growth factor-23 (FGF-23) in a sample, which comprise the following steps: (1) reacting, in an aqueous medium, FGF-23 in a sample with magnetic particles, a first antibody or a fragment thereof which binds to FGF-23, and a second antibody or a fragment thereof which binds to FGF-23, to form on the magnetic particles an immunocomplex comprising the first antibody or a fragment thereof which binds to FGF-23, FGF-23, and the second antibody or a fragment thereof which binds to FGF-23; (2) collecting the magnetic particles in the reaction mixture after step (1) by magnetic force, and separating the magnetic particles collected by magnetic force from the other components; and (3) measuring the immunocomplex on the magnetic particles separated in step (2). The present invention provides a method for measuring FGF-23 in a sample, which have a high sensitivity and have a wide measurement range.

4. 发明授权

US4346922A Device for preventing leakage at pipe joints 失效
标题翻译：管接头防止泄漏的装置
公开(公告)号：US4346922A
公开(公告)日：1982-08-31
申请号：US132543
申请日：1980-03-21
申请人： Hisao Ohtsuga , Koji Uzawa , Takashi Kamuro , Susumu Sudo , Tomoyoshi Hirose , Masafumi Miyao , Motoyuki Koga
发明人： Hisao Ohtsuga , Koji Uzawa , Takashi Kamuro , Susumu Sudo , Tomoyoshi Hirose , Masafumi Miyao , Motoyuki Koga
IPC分类号： F16L55/163 , F16L21/00
CPC分类号： F16L55/163 , Y10S285/915
摘要： This device comprises a cylindrical member integrally made of an elastic material for covering the inside periphery of a pipe joint, belt members impregnated with a bonding agent to be squeezed out by pressure, and circular expanding members for expanding said cylindrical member when positioned inside the cylindrical member and subsequently expanded. The respective belt members are wound around the outside peripheral surface of the cylindrical member at its longitudinal ends and the respective expanding members are brought into contact with the inside peripheral surface of the cylindrical member at both its longitudinal ends, so that by radially expanding the cylindrical member at both its longitudinal ends by the respective expanding members, the respective belt members are pressed against the inside peripheral portions of the pipes on both sides of the joint for squeezing out the bonding agent from the belt members by such pressure and thereby attaining an airtight and watertight bonding between the outside peripheral surface of the cylindrical member at both its longitudinal ends and the inside peripheral surfaces of the pipes.
摘要翻译：该装置包括：一个由弹性材料制成的圆柱形构件，用于覆盖管接头的内周;浸渍有待压出的粘结剂的带构件;以及用于当圆柱形构件位于圆柱形成员并随后扩大。相应的带构件在其纵向端部缠绕在圆柱形构件的外周表面上，并且各个扩展构件在其两个纵向端部与圆筒构件的内周面接触，从而通过径向扩大圆柱形通过相应的膨胀构件在其两个纵向端部处，相应的带构件被压靠在接头两侧的管的内周边部分中，以通过这种压力从带构件挤出粘合剂，从而实现气密并且在其两个纵向端部处的圆柱形构件的外周表面和管的内周表面之间的水密结合。

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