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1. 发明授权

US07909465B2 Characterising eye-related optical systems 有权
标题翻译：表征眼睛相关的光学系统
公开(公告)号：US07909465B2
公开(公告)日：2011-03-22
申请号：US12593543
申请日：2008-03-28
申请人： Arthur Ho , Brien Anthony Holden , Klaus Ehrmann
发明人： Arthur Ho , Brien Anthony Holden , Klaus Ehrmann
IPC分类号： A61B3/10 , A61B3/00
CPC分类号： A61B3/103 , A61B3/0008 , A61B3/1005 , A61B3/1015
摘要： An instrument and method for characterizing eye-related optical systems, including the live human eye involves scanning an illuminating light beam from a light source and light detector unit from element to element of a beam deflector array of elements arranged laterally across the optical axis of eye. At each successive element the illuminating beam is deflected to form an interrogating beam that is directed into the eye at a peripheral angle that depends upon the lateral location of the deflector element. A return beam is reflected or back-scattered from the cornea and returned via the same deflector element to the light source and detector unit. This allows the interrogating beams to be scanned sufficiently rapidly into the eye to greatly reduce the variation of eye fixation and gaze that accompany other methods of measuring peripheral refraction or aberration of a natural eye. In addition to or instead of scanning the illuminating beam over each element of the array, all or multiple elements of the array can be illuminated simultaneously and the multiple interrogating rays thus generated can be gated by the use of an LCD aperture plate. Alternatively, an LCD aperture plate can be interposed between a wide illuminating beam and operated to selectively illuminate the beam deflector.
摘要翻译：用于表征眼睛相关的光学系统（包括活人眼）的仪器和方法涉及扫描来自光源和光检测器单元的照明光束，从光束偏转器阵列的元件到元件横向穿过眼睛的光轴。在每个连续元件处，照明光束被偏转以形成以取决于偏转元件的横向位置的圆周角度引导到眼睛中的询问光束。返回光束从角膜反射或反向散射，并通过相同的偏转元件返回到光源和检测器单元。这样就可以将询问光束快速扫描到眼睛中，以大大减少测量周边折射或自然眼睛畸变的其他测量方法的眼睛固定和注视的变化。除了或代替扫描阵列的每个元件上的照明光束之外，阵列的全部或多个元件可以被同时照明，并且由此产生的多个询问光线可以通过使用LCD孔板来选通。或者，LCD孔板可以插入在宽照明光束之间并且被操作以选择性地照射光束偏转器。

2. 发明申请

US20110176113A1 Characterising Eye-Related Optical Systems 审中-公开
标题翻译：表征眼睛相关的光学系统
公开(公告)号：US20110176113A1
公开(公告)日：2011-07-21
申请号：US13053073
申请日：2011-03-21
申请人： Arthur Ho , Brien Anthony Holden , Klaus Ehrmann
发明人： Arthur Ho , Brien Anthony Holden , Klaus Ehrmann
IPC分类号： A61B3/10
CPC分类号： A61B3/103 , A61B3/0008 , A61B3/1005 , A61B3/1015
摘要： An instrument and method for characterising eye-related optical systems, including the live human eye (18) involves scanning an illuminating light beam (22) from a light source and light detector unit (20) from element to element of a beam deflector array (12) of elements (14) arranged laterally across the optical axis (16) of eye (18). At each successive element (14) the illuminating beam (22) is deflected to form an interrogating beam (24) that is directed into the eye (18) at a peripheral angle that depends upon the lateral location of the deflector element. A return beam (23) is reflected or back-scattered from the cornea (38) and returned via the same deflector element to the light source and detector unit (20). This allows the interrogating beams to be scanned sufficiently rapidly into the eye to greatly reduce the variation of eye fixation and gaze that accompany other methods of measuring peripheral refraction or aberration of a natural eye. In addition to or instead of scanning the illumination beam (22) over each element (14) of the array (12), all or multiple elements (14) of the array (12) can be illuminated simultaneously and the multiple interrogating rays (24) thus generated can be gated by the use of an LCD aperture plate (26). Alternatively, an LCD aperture plate (28) can be interposed between a wide illuminating beam (22) and operated to selectively illuminate the beam deflector.
摘要翻译：用于表征包括活人眼（18）的眼睛相关光学系统的仪器和方法涉及从光源和光检测器单元（20）从光束偏转器阵列的元件到元件扫描照明光束（22） 12）横向穿过眼睛（18）的光轴（16）布置的元件（14）。在每个连续的元件（14）处，照明光束（22）被偏转以形成询问光束（24），其以取决于偏转器元件的横向位置的圆周角度被引导到眼睛（18）中。返回光束（23）从角膜（38）反射或反向散射并通过相同的偏转元件返回到光源和检测器单元（20）。这样就可以将询问光束快速扫描到眼睛中，以大大减少测量周边折射或自然眼睛畸变的其他测量方法的眼睛固定和注视的变化。除了扫描阵列（12）的每个元件（14）上的照明光束（22）之外或代替扫描阵列（12）的全部或多个元件（14）可以被同时照明，并且多个询问光线（24 ）可以通过使用LCD孔板（26）来选通。或者，LCD孔板（28）可以插入在宽照明光束（22）之间并被操作以选择性地照射光束偏转器。

3. 发明申请

US20100225883A1 CHARACTERISING EYE-RELATED OPTICAL SYSTEMS 有权
标题翻译：表征与眼睛相关的光学系统
公开(公告)号：US20100225883A1
公开(公告)日：2010-09-09
申请号：US12593543
申请日：2008-03-28
申请人： Arthur Ho , Brien Anthony Holden , Klaus Ehrmann
发明人： Arthur Ho , Brien Anthony Holden , Klaus Ehrmann
IPC分类号： A61B3/10
CPC分类号： A61B3/103 , A61B3/0008 , A61B3/1005 , A61B3/1015
摘要： An instrument and method for characterising eye-related optical systems, including the live human eye involves scanning an illuminating light beam from a light source and light detector unit from element to element of a beam deflector array of elements arranged laterally across the optical axis of eye. At each successive element the illuminating beam is deflected to form an interrogating beam that is directed into the eye at a peripheral angle that depends upon the lateral location of the deflector element. A return beam is reflected or back-scattered from the cornea and returned via the same deflector element to the light source and detector unit. This allows the interrogating beams to be scanned sufficiently rapidly into the eye to greatly reduce the variation of eye fixation and gaze that accompany other methods of measuring peripheral refraction or aberration of a natural eye. In addition to or instead of scanning the illuminating beam over each element of the array, all or multiple elements of the array can be illuminated simultaneously and the multiple interrogating rays thus generated can be gated by the use of an LCD aperture plate. Alternatively, an LCD aperture plate can be interposed between a wide illuminating beam and operated to selectively illuminate the beam deflector
摘要翻译：用于表征眼睛相关的光学系统（包括活人眼）的仪器和方法涉及扫描来自光源和光检测器单元的照明光束，从光束偏转器阵列的元件到元件横向穿过眼睛的光轴。在每个连续元件处，照明光束被偏转以形成以取决于偏转元件的横向位置的圆周角度引导到眼睛中的询问光束。返回光束从角膜反射或反向散射，并通过相同的偏转元件返回到光源和检测器单元。这样就可以将询问光束快速扫描到眼睛中，以大大减少测量周边折射或自然眼睛畸变的其他测量方法的眼睛固定和注视的变化。除了或代替扫描阵列的每个元件上的照明光束之外，阵列的全部或多个元件可以被同时照明，并且由此产生的多个询问光线可以通过使用LCD孔板来选通。或者，LCD孔板可以插入在宽照明光束之间并且被操作以选择性地照射光束偏转器

4. 发明授权

US08672473B2 Myopia control means 有权
标题翻译：近视控制手段
公开(公告)号：US08672473B2
公开(公告)日：2014-03-18
申请号：US12988403
申请日：2009-04-20
申请人： Aldo Abraham Martinez , Arthur Ho , Padmaja Rajagopal Sankaridurg , Percy Fabian Lazon , Brien Anthony Holden , Rick Payor , Gregor F. Schmid
发明人： Aldo Abraham Martinez , Arthur Ho , Padmaja Rajagopal Sankaridurg , Percy Fabian Lazon , Brien Anthony Holden , Rick Payor , Gregor F. Schmid
IPC分类号： G02C7/02
CPC分类号： G02C7/06 , A61B3/0025 , G02C7/02 , G02C7/027 , G02C7/04 , G02C7/041 , G02C7/044 , G02C13/003 , G02C2202/08 , G02C2202/16 , G02C2202/24
摘要： Sets, kits or stocks of anti-myopia contact or spectacle lenses, along with methods for their use, that do not require a clinician to measure peripheral refractive error in the eyes of myopic patients. Extensive surveys have shown that lenses having peripheral powers or defocus set in accordance with central corrective power will cover almost all normal myopes not worse than −6 D central refractive error. In one example, a kit or set of lenses (50, FIG. 15) can have multiple parts or sub-sets (52, 54) each comprising a compartmented container (56a, 56b) with lenses (58a, 58b) arranged according to increments of central corrective power (59a, 59b). The lenses (58a) of the first part (52) have four steps (60a, 61a, 62a, 64a) of peripheral power or defocus to pro vide therapeutic effect and, while the lenses (58b) of the second part (54) also have four steps (60b, 61b, 62b, 64b), the level of therapeutic effect is higher. Other examples of sets, kits and stocks, as well as examples of lenses themselves, are disclosed together with methods of use.
摘要翻译：抗近视接触眼镜镜片的套件，套件或库存，以及使用方法，不需要临床医生测量近视患者眼睛的周边屈光不正。广泛的调查显示，具有根据中心矫正力设置的外围功率或散焦的镜片将覆盖几乎所有正常的近视眼，不会比-6 D中心屈光不正差。在一个示例中，套件或一组透镜（50，图15）可以具有多个部件或子组件（52,54），每个部件或子组件包括具有透镜（58a，58b）的分隔的容器（56a，56b）中央矫正力的增量（59a，59b）。第一部分（52）的透镜（58a）具有周边功率或散焦的四个台阶（60a，61a，62a，64a）以提供治疗效果，并且当第二部分（54）的透镜（58b）也具有四个步骤（60b，61b，62b，64b），治疗效果的水平较高。集合，套件和股票的其他示例以及透镜本身的示例与所使用的方法一起公开。

5. 发明授权

US08439974B2 Adjusted index of refraction of ocular replacement material 失效
$Adjusted index of refraction of ocular replacement material$
标题翻译：调整眼睛替代材料的折射率
公开(公告)号：US08439974B2
公开(公告)日：2013-05-14
申请号：US12299239
申请日：2007-05-03
申请人： Arthur Ho , Brien Anthony Holden , Fabrice Manns , Jean-Marie Arthur Parel
发明人： Arthur Ho , Brien Anthony Holden , Fabrice Manns , Jean-Marie Arthur Parel
IPC分类号： A61F2/16
CPC分类号： A61F2/16 , A61F2/1624 , A61F2240/002 , A61L27/18 , A61L27/50 , A61L2430/16 , C08L83/04
摘要： The present invention relates to a method of determining the IOL refractive index for an ocular replacement material for replacing tissue in the capsular bag comprising combining a neutral (non-correcting) reference refractive index (“NRRI”) of between 1.421 and 1.450 with a refractive index correction factor (“RICF”) ascertained by reference to the refractive power required to correct the patient's refractive error. The present invention also relates to methods of treating presbyopia, myopia and hyperopia using the above method.
摘要翻译：本发明涉及一种确定用于更换囊袋中的组织的眼睛替代材料的IOL折射率的方法，包括将1.421和1.450之间的中性（非校正）参考折射率（“NRRI”）与折射率通过参考校正患者的屈光不正所需的屈光力确定的指数校正因子（“RICF”）。本发明还涉及使用上述方法治疗老花眼，近视和远视的方法。

6. 发明授权

US07766482B2 Methods and apparatuses for altering relative curvature of field and positions of peripheral, off-axis focal positions 有权
标题翻译：用于改变外围相对曲率和外围焦点位置位置的方法和装置
公开(公告)号：US07766482B2
公开(公告)日：2010-08-03
申请号：US12399207
申请日：2009-03-06
申请人： Earl Leo Smith, III , Nelson Greeman, Jr. , Patsy Greeman, legal representative , Arthur Ho , Brien Anthony Holden
发明人： Earl Leo Smith, III , Nelson Greeman, Jr. , Arthur Ho , Brien Anthony Holden
IPC分类号： A61B3/10
CPC分类号： A61F9/00804 , A61B3/00 , A61F2/145 , A61F2/16 , A61F2/1613 , A61F9/00821 , A61F2002/1699 , A61F2009/00872 , G02C7/02 , G02C7/042 , G02C7/047 , G02C2202/20 , G02C2202/24
摘要： A method and apparatus are disclosed for controlling optical aberrations to alter relative curvature of field by providing ocular apparatuses, systems and methods comprising a predetermined corrective factor to produce at least one substantially corrective stimulus for repositioning peripheral, off-axis, focal points relative to the central, on-axis or axial focal point while maintaining the positioning of the central, on-axis or axial focal point on the retina. The invention will be used to provide continuous, useful clear visual images while simultaneously retarding or abating the progression of myopia or hypermetropia.
摘要翻译：公开了一种用于控制光学像差以改变相对场景的方法和装置，其通过提供包括预定校正因子的眼睛装置，系统和方法来产生至少一个基本上校正的刺激，用于重新定位周边，离轴的焦点相对于中心，轴上或轴向焦点，同时保持视网膜上的中心，轴上或轴向焦点的定位。本发明将用于提供连续，有用的清晰视觉图像，同时延缓或减轻近视或远视的进展。

7. 发明申请

US20100110371A1 Method and Apparatus for Controlling Peripheral Image Position for Reducing Progression of Myopia 有权
标题翻译：用于控制用于减少近视进展的外围图像位置的方法和装置
公开(公告)号：US20100110371A1
公开(公告)日：2010-05-06
申请号：US12685083
申请日：2010-01-11
申请人： Arthur Ho , Earl Leo Smith, III , Padmaja Sankaridurg , Brien Anthony Holden
发明人： Arthur Ho , Earl Leo Smith, III , Padmaja Sankaridurg , Brien Anthony Holden
IPC分类号： G02C7/06
CPC分类号： G02C7/02 , A61F9/008 , A61F2009/00872 , G02C7/047 , G02C2202/24
摘要： A method and apparatus are disclosed for controlling optical aberrations to alter relative curvature of field by providing optical devices and methods comprising the repositioning of peripheral off-axis focal points relative to the retina to produce stimulus for influencing the progression of refractive error while simultaneously controlling the position of the central focal point near to the retina to provide clear central vision and simultaneously providing zones of controlled peripheral defocus and other optical aberrations to improve peripheral vision for select directions of gaze.
摘要翻译：公开了一种通过提供光学装置和方法来控制光学像差以改变相对曲率的方法和装置，所述光学装置和方法包括相对于视网膜重新定位外围离轴焦点，以产生用于影响屈光不正的进展的刺激，同时控制中心焦点靠近视网膜的位置，以提供清晰的中央视觉，同时提供受控外围散焦和其他光学像差的区域，以改善注视方向的周边视力。

8. 发明申请

US20090161065A1 Methods and Apparatuses for Altering Relative Curvature of Field and Positions of Peripheral, Off-Axis Focal Positions 有权
标题翻译：用于改变外围，离轴焦点位置的场和位置的相对曲率的方法和装置
公开(公告)号：US20090161065A1
公开(公告)日：2009-06-25
申请号：US12399207
申请日：2009-03-06
申请人： Earl Leo Smith, III , Nelson Greeman, JR. , Patsy Greeman , Arthur Ho , Brien Anthony Holden
发明人： Earl Leo Smith, III , Nelson Greeman, JR. , Patsy Greeman , Arthur Ho , Brien Anthony Holden
IPC分类号： G02C7/06
CPC分类号： A61F9/00804 , A61B3/00 , A61F2/145 , A61F2/16 , A61F2/1613 , A61F9/00821 , A61F2002/1699 , A61F2009/00872 , G02C7/02 , G02C7/042 , G02C7/047 , G02C2202/20 , G02C2202/24
摘要： A method and apparatus are disclosed for controlling optical aberrations to alter relative curvature of field by providing ocular apparatuses, systems and methods comprising a predetermined corrective factor to produce at least one substantially corrective stimulus for repositioning peripheral, off-axis, focal points relative to the central, on-axis or axial focal point while maintaining the positioning of the central, on-axis or axial focal point on the retina. The invention will be used to provide continuous, useful clear visual images while simultaneously retarding or abating the progression of myopia or hypermetropia.
摘要翻译：公开了一种用于控制光学像差以改变相对场景的方法和装置，其通过提供包括预定校正因子的眼睛装置，系统和方法来产生至少一个基本上校正的刺激，用于重新定位周边，离轴的焦点相对于中心，轴上或轴向焦点，同时保持视网膜上的中心，轴上或轴向焦点的定位。本发明将用于提供连续，有用的清晰视觉图像，同时延缓或减轻近视或远视的进展。

9. 发明申请

US20090122264A1 Methods and Apparatuses for Enhancing Peripheral Vision 有权
标题翻译：用于增强外周视觉的方法和装置
公开(公告)号：US20090122264A1
公开(公告)日：2009-05-14
申请号：US12256705
申请日：2008-10-23
申请人： Arthur Ho , Andrew Robert Whatham , Brien Anthony Holden , Padmaja Rajagopal Sankaridurg , Aldo Abraham Martinez , Earl Leo Smith, III
发明人： Arthur Ho , Andrew Robert Whatham , Brien Anthony Holden , Padmaja Rajagopal Sankaridurg , Aldo Abraham Martinez , Earl Leo Smith, III
IPC分类号： A61B3/00 , G02C7/02 , G02C7/06
CPC分类号： C08L19/006 , C08C19/42 , C08C19/44 , C08F136/04 , G02C7/042 , G02C7/047 , G02C2202/24 , C08F4/545 , C08F4/48
摘要： Methods and apparatuses are disclosed for improving peripheral vision by positioning the peripheral image points at a pre-determined and precise position relative to the retina to achieve optimal performance according to one or more pre-selected criteria parameters for optimal peripheral vision performance.
摘要翻译：公开了用于通过将周边图像点定位在相对于视网膜的预定和精确位置来改善周边视觉的方法和装置，以根据一个或多个预先选择的准则参数实现最佳性能，以获得最佳周边视觉性能。

10. 发明授权

US08931897B2 Contact lenses for myopic eyes and methods of treating myopia 有权
标题翻译：用于近视眼的隐形眼镜和治疗近视的方法
公开(公告)号：US08931897B2
公开(公告)日：2015-01-13
申请号：US13581996
申请日：2011-03-03
申请人： Brien Anthony Holden , Gregor Schmid , Padmaja Rajagopal Sankaridurg , Arthur Ho , Percy Fabian Lazon , Aldo Abraham Martinez Magos , Earl Leo Smith, III
发明人： Brien Anthony Holden , Gregor Schmid , Padmaja Rajagopal Sankaridurg , Arthur Ho , Percy Fabian Lazon , Aldo Abraham Martinez Magos , Earl Leo Smith, III
IPC分类号： G02C7/04
CPC分类号： G02C7/044 , G02C7/041 , G02C7/045 , G02C7/047 , G02C7/063 , G02C2202/06 , G02C2202/24
摘要： A contact lens and a method for treating an eye with myopia is described. The contact lens includes an inner optic zone and an outer optic zone. The outer optic zone includes at least a portion with a first power, selected to correct distance vision. The inner optic zone has a relatively more positive power (an add power). In some embodiments the add power is substantially constant across the inner optic zone. In other embodiments the add power is variable across the inner optic zone. While in some embodiments the inner optic zone has a power designed to substantially eliminate lag of accommodation in the eye with myopia, in other embodiments, the add power may be higher.
摘要翻译：描述了隐形眼镜和用于治疗近视眼的方法。隐形眼镜包括内部光学区域和外部光学区域。外部光学区域至少包括具有第一功率的部分，其被选择用于校正距离视力。内部光学区具有相对较大的正功率（增加功率）。在一些实施例中，所述附加功率在所述内部光学区域内基本恒定。在其他实施例中，增加功率在内部光学区域是可变的。虽然在一些实施例中，内部光学区具有设计为基本上消除眼睛中具有近视眼的适应滞后的功率，但在其他实施例中，附加功率可能更高。

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