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1. 发明授权

US07957820B2 Conduction block verification probe and method of use 有权
标题翻译：导电块验证探头和使用方法
公开(公告)号：US07957820B2
公开(公告)日：2011-06-07
申请号：US12323374
申请日：2008-11-25
申请人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster , Mathew Williams
发明人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster , Mathew Williams
IPC分类号： A61N1/00
CPC分类号： A61B18/14 , A61B1/12 , A61B5/0536 , A61B5/6852 , A61B18/1402 , A61B18/1442 , A61B18/1477 , A61B18/148 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/22051 , A61B2017/2945 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0022 , A61B2018/00291 , A61B2018/00345 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00404 , A61B2018/00577 , A61B2018/00875 , A61B2018/00982 , A61B2018/0225 , A61B2018/0262 , A61B2018/126 , A61B2018/1425 , A61B2018/1432 , A61B2090/373 , A61B2090/378 , A61N1/0587
摘要： Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often be used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like. Although devices and methods of the invention may be used to ablate epicardial tissue to treat atrial fibrillation, they may also be used in veterinary or research contexts, to treat various heart conditions other than atrial fibrillation and/or to ablate cardiac tissue other than the epicardium.
摘要翻译：装置和方法提供用于治疗心律失常的心脏组织的消融，例如心房颤动。虽然通常使用装置和方法来消融至少一个肺静脉附近的心外膜组织，但是可以使用各种实施例来消融心脏上其他位置的其他心脏组织。装置通常包括用于接触心外膜组织并将消融装置固定到心外膜组织的至少一个组织接触构件以及用于烧蚀组织的至少一个消融构件。各种实施例包括诸如抽吸孔的特征，其使得装置能够以足够的强度附着到心外膜表面，以允许组织通过装置稳定。例如，一些实施例可用于稳定跳动心脏以实现搏动心脏消融手术。可以通过微创导引器装置等将许多装置引入患者体内。尽管本发明的装置和方法可用于消融心外膜组织以治疗房颤，但它们也可用于兽医学或研究领域，以治疗心房颤动以外的各种心脏病和/或除心外膜外的心脏组织。

2. 发明授权

US07542807B2 Conduction block verification probe and method of use 有权
标题翻译：导电块验证探头和使用方法
公开(公告)号：US07542807B2
公开(公告)日：2009-06-02
申请号：US11186149
申请日：2005-07-20
申请人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster , Mathew Williams
发明人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster , Mathew Williams
IPC分类号： A61N1/04 , A61N1/05
CPC分类号： A61B18/14 , A61B1/12 , A61B5/0536 , A61B5/6852 , A61B18/1402 , A61B18/1442 , A61B18/1477 , A61B18/148 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/22051 , A61B2017/2945 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0022 , A61B2018/00291 , A61B2018/00345 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00404 , A61B2018/00577 , A61B2018/00875 , A61B2018/00982 , A61B2018/0225 , A61B2018/0262 , A61B2018/126 , A61B2018/1425 , A61B2018/1432 , A61B2090/373 , A61B2090/378 , A61N1/0587
摘要： Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often to be used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure.
摘要翻译：装置和方法提供用于治疗心律失常的心脏组织的消融，例如心房颤动。尽管通常将装置和方法用于消融至少一个肺静脉附近的心外膜组织，但是可以使用各种实施例来消融心脏上其他位置的其他心脏组织。装置通常包括用于接触心外膜组织并将消融装置固定到心外膜组织的至少一个组织接触构件以及用于烧蚀组织的至少一个消融构件。各种实施例包括诸如抽吸孔的特征，其使得装置能够以足够的强度附着到心外膜表面，以允许组织通过装置稳定。例如，一些实施例可用于稳定跳动心脏以实现搏动心脏消融手术。

3. 发明申请

US20090076503A1 CONDUCTION BLOCK VERIFICATION PROBE AND METHOD OF USE 有权
标题翻译：导线块验证探头和使用方法
公开(公告)号：US20090076503A1
公开(公告)日：2009-03-19
申请号：US12323374
申请日：2008-11-25
申请人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster , Mathew Williams
发明人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster , Mathew Williams
IPC分类号： A61B18/18
CPC分类号： A61B18/14 , A61B1/12 , A61B5/0536 , A61B5/6852 , A61B18/1402 , A61B18/1442 , A61B18/1477 , A61B18/148 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/22051 , A61B2017/2945 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0022 , A61B2018/00291 , A61B2018/00345 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00404 , A61B2018/00577 , A61B2018/00875 , A61B2018/00982 , A61B2018/0225 , A61B2018/0262 , A61B2018/126 , A61B2018/1425 , A61B2018/1432 , A61B2090/373 , A61B2090/378 , A61N1/0587
摘要： Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often be used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like. Although devices and methods of the invention may be used to ablate epicardial tissue to treat atrial fibrillation, they may also be used in veterinary or research contexts, to treat various heart conditions other than atrial fibrillation and/or to ablate cardiac tissue other than the epicardium.
摘要翻译：装置和方法提供用于治疗心律失常的心脏组织的消融，例如心房颤动。虽然通常使用装置和方法来消融至少一个肺静脉附近的心外膜组织，但是可以使用各种实施例来消融心脏上其他位置的其他心脏组织。装置通常包括用于接触心外膜组织并将消融装置固定到心外膜组织的至少一个组织接触构件以及用于烧蚀组织的至少一个消融构件。各种实施例包括诸如抽吸孔的特征，其使得装置能够以足够的强度附着到心外膜表面，以允许组织通过装置稳定。例如，一些实施例可用于稳定跳动心脏以实现搏动心脏消融手术。可以通过微创导引器装置等将许多装置引入患者体内。尽管本发明的装置和方法可用于消融心外膜组织以治疗房颤，但它们也可用于兽医学或研究领域，以治疗心房颤动以外的各种心脏病和/或除心外膜外的心脏组织。

4. 发明申请

US20110009853A1 LEFT ATRIAL APPENDAGE DEVICES AND METHODS 审中-公开
标题翻译：左边的附件设备和方法
公开(公告)号：US20110009853A1
公开(公告)日：2011-01-13
申请号：US12886436
申请日：2010-09-20
申请人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster
发明人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster
IPC分类号： A61B18/20 , A61B17/08 , A61B17/10 , A61B18/18
CPC分类号： A61B17/083 , A61B17/0057 , A61B17/068 , A61B17/08 , A61B17/122 , A61B17/1285 , A61B17/320016 , A61B2017/00243
摘要： Devices and methods for clamping tissue and/or moving two tissue structures together by moving two plates or arm together. The pressure or force applied to the tissue may be used to bring the tissue together, to seal an opening or to cut through and remove a portion of the tissue. In one procedure disclosed, a clip applier may be used to apply one or more clips to the left atrial appendage of the heart to prevent clots from the left atrial appendage from embolizing and causing harm to the patient, such as a stroke.
摘要翻译：通过将两个板或臂一起移动来夹紧组织和/或移动两个组织结构在一起的装置和方法。施加到组织的压力或力可以用于将组织带到一起，以密封开口或切割并去除组织的一部分。在所公开的一个程序中，施夹器可用于将一个或多个夹子应用于心脏的左心耳，以防止左心耳附近的血栓栓塞并对患者造成伤害，例如中风。

5. 发明授权

US10098640B2 Left atrial appendage devices and methods 审中-公开
公开(公告)号：US10098640B2
公开(公告)日：2018-10-16
申请号：US12886436
申请日：2010-09-20
申请人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster
发明人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster
IPC分类号： A61B17/08 , A61B17/10 , A61B17/122 , A61B17/128 , A61B17/068 , A61B17/00 , A61B17/32
CPC分类号： A61B17/083 , A61B17/0057 , A61B17/068 , A61B17/08 , A61B17/122 , A61B17/1285 , A61B17/320016 , A61B2017/00243
摘要： Devices and methods for clamping tissue and/or moving two tissue structures together by moving two plates or arm together. The pressure or force applied to the tissue may be used to bring the tissue together, to seal an opening or to cut through and remove a portion of the tissue. In one procedure disclosed, a clip applier may be used to apply one or more clips to the left atrial appendage of the heart to prevent clots from the left atrial appendage from embolizing and causing harm to the patient, such as a stroke.

6. 发明申请

US20180310936A9 LEFT ATRIAL APPENDAGE DEVICES AND METHODS 审中-公开
公开(公告)号：US20180310936A9
公开(公告)日：2018-11-01
申请号：US12886436
申请日：2010-09-20
申请人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster
发明人： Arthur A. Bertolero , Tamer Ibrahim , Steve Geyster
IPC分类号： A61B17/08 , A61B17/122 , A61B17/068 , A61B17/128 , A61B17/00 , A61B17/32
CPC分类号： A61B17/083 , A61B17/0057 , A61B17/068 , A61B17/08 , A61B17/122 , A61B17/1285 , A61B17/320016 , A61B2017/00243
摘要： Devices and methods for clamping tissue and/or moving two tissue structures together by moving two plates or arm together. The pressure or force applied to the tissue may be used to bring the tissue together, to seal an opening or to cut through and remove a portion of the tissue. In one procedure disclosed, a clip applier may be used to apply one or more clips to the left atrial appendage of the heart to prevent clots from the left atrial appendage from embolizing and causing harm to the patient, such as a stroke.

7. 发明申请

US20060015165A1 Conduction block verification probe and method of use 有权
标题翻译：导电块验证探头和使用方法
公开(公告)号：US20060015165A1
公开(公告)日：2006-01-19
申请号：US11186149
申请日：2005-07-20
申请人： Arthur Bertolero , Tamer Ibrahim , Steve Geyster , Mathew Williams
发明人： Arthur Bertolero , Tamer Ibrahim , Steve Geyster , Mathew Williams
IPC分类号： A61B5/042 , A61N1/05
CPC分类号： A61B18/14 , A61B1/12 , A61B5/0536 , A61B5/6852 , A61B18/1402 , A61B18/1442 , A61B18/1477 , A61B18/148 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/22051 , A61B2017/2945 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0022 , A61B2018/00291 , A61B2018/00345 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00404 , A61B2018/00577 , A61B2018/00875 , A61B2018/00982 , A61B2018/0225 , A61B2018/0262 , A61B2018/126 , A61B2018/1425 , A61B2018/1432 , A61B2090/373 , A61B2090/378 , A61N1/0587
摘要： Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often be used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like. Although devices and methods of the invention may be used to ablate epicardial tissue to treat atrial fibrillation, they may also be used in veterinary or research contexts, to treat various heart conditions other than atrial fibrillation and/or to ablate cardiac tissue other than the epicardium.
摘要翻译：装置和方法提供用于治疗心律失常的心脏组织的消融，例如心房颤动。虽然通常使用装置和方法来消融至少一个肺静脉附近的心外膜组织，但是可以使用各种实施例来消融心脏上其他位置的其他心脏组织。装置通常包括用于接触心外膜组织并将消融装置固定到心外膜组织的至少一个组织接触构件以及用于烧蚀组织的至少一个消融构件。各种实施例包括诸如抽吸孔的特征，其使得装置能够以足够的强度附着到心外膜表面，以允许组织通过装置稳定。例如，一些实施例可用于稳定跳动心脏以实现搏动心脏消融手术。可以通过微创导引器装置等将许多装置引入患者体内。尽管本发明的装置和方法可用于消融心外膜组织以治疗房颤，但它们也可用于兽医学或研究领域，以治疗心房颤动以外的各种心脏病和/或除心外膜外的心脏组织。

8. 发明授权

US07931579B2 Tissue positioner 有权
标题翻译：组织定位器
公开(公告)号：US07931579B2
公开(公告)日：2011-04-26
申请号：US11512796
申请日：2006-08-29
申请人： Arthur A. Bertolero , Tamer Ibrahim
发明人： Arthur A. Bertolero , Tamer Ibrahim
IPC分类号： A61F13/00
CPC分类号： A61B17/0206 , A61B2017/0237 , A61B2017/308
摘要： Apparatus and methods for stabilizing and/or positioning tissues or organs during surgical procedures. One feature of the positioners of the invention includes the use of one or more suction elements used to grip the organ or tissue. The main body of the suction element comprises body defining a polyhedral shaped chamber, an elliptical ring structure and a vacuum port. The invention further includes structures to support the suction element and hold the suction element and attached tissue in a fixed position including catheters, lockable flexible arms, and retractors.
摘要翻译：用于在外科手术过程中稳定和/或定位组织或器官的装置和方法。本发明的定位器的一个特征包括使用一个或多个用于夹紧器官或组织的抽吸元件。抽吸元件的主体包括限定多面体形状的室，椭圆环结构和真空端口的主体。本发明还包括用于支撑抽吸元件并将抽吸元件和附着的组织保持在包括导管，可锁定的柔性臂和牵开器的固定位置的结构。

9. 发明授权

US07226448B2 Cardiac treatment devices and methods 有权
标题翻译：心脏治疗装置及方法
公开(公告)号：US07226448B2
公开(公告)日：2007-06-05
申请号：US10410618
申请日：2003-04-08
申请人： Arthur A. Bertolero , Tamer Ibrahim , Daniel J. Conley
发明人： Arthur A. Bertolero , Tamer Ibrahim , Daniel J. Conley
IPC分类号： A61B18/18
CPC分类号： A61B18/1492 , A61B1/12 , A61B18/14 , A61B18/1402 , A61B18/1442 , A61B18/1445 , A61B18/18 , A61B2017/00243 , A61B2017/22051 , A61B2017/2945 , A61B2018/00023 , A61B2018/00029 , A61B2018/00291 , A61B2018/00345 , A61B2018/00351 , A61B2018/00363 , A61B2018/00404 , A61B2018/00577 , A61B2018/00875 , A61B2018/00982 , A61B2018/126 , A61B2018/1432
摘要： Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often be used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like. Although devices and methods of the invention may be used to ablate epicardial tissue to treat atrial fibrillation, they may also be used in veterinary or research contexts, to treat various heart conditions other than atrial fibrillation and/or to ablate cardiac tissue other than the epicardium.
摘要翻译：装置和方法提供用于治疗心律失常的心脏组织的消融，例如心房颤动。虽然通常使用装置和方法来消融至少一个肺静脉附近的心外膜组织，但是可以使用各种实施例来消融心脏上其他位置的其他心脏组织。装置通常包括用于接触心外膜组织并将消融装置固定到心外膜组织的至少一个组织接触构件以及用于烧蚀组织的至少一个消融构件。各种实施例包括诸如抽吸孔的特征，其使得装置能够以足够的强度附着到心外膜表面，以允许组织通过装置稳定。例如，一些实施例可用于稳定跳动心脏以实现搏动心脏消融手术。可以通过微创导引器装置等将许多装置引入患者体内。尽管本发明的装置和方法可用于消融心外膜组织以治疗房颤，但它们也可用于兽医学或研究领域，以治疗心房颤动以外的各种心脏病和/或除心外膜外的心脏组织。

10. 发明授权

US08545498B2 Cardiac ablation devices and methods 有权
标题翻译：心脏消融装置及方法
公开(公告)号：US08545498B2
公开(公告)日：2013-10-01
申请号：US12564821
申请日：2009-09-22
申请人： Arthur A. Bertolero , Tamer Ibrahim
发明人： Arthur A. Bertolero , Tamer Ibrahim
IPC分类号： A61B18/18
CPC分类号： A61B18/00 , A61B1/12 , A61B5/0536 , A61B18/14 , A61B18/1402 , A61B18/1442 , A61B18/1477 , A61B18/148 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00243 , A61B2017/22051 , A61B2017/2945 , A61B2018/00011 , A61B2018/00023 , A61B2018/00029 , A61B2018/00083 , A61B2018/0022 , A61B2018/00291 , A61B2018/00345 , A61B2018/00351 , A61B2018/00363 , A61B2018/00375 , A61B2018/00404 , A61B2018/00577 , A61B2018/00875 , A61B2018/00982 , A61B2018/0225 , A61B2018/0262 , A61B2018/126 , A61B2018/1425 , A61B2018/1432 , A61B2090/373 , A61B2090/378 , A61N1/0587
摘要： Devices and methods provide for ablation of cardiac tissue for treating cardiac arrhythmias such as atrial fibrillation. Although the devices and methods are often used to ablate epicardial tissue in the vicinity of at least one pulmonary vein, various embodiments may be used to ablate other cardiac tissues in other locations on a heart. Devices generally include at least one tissue contacting member for contacting epicardial tissue and securing the ablation device to the epicardial tissue, and at least one ablation member for ablating the tissue. Various embodiments include features, such as suction apertures, which enable the device to attach to the epicardial surface with sufficient strength to allow the tissue to be stabilized via the device. For example, some embodiments may be used to stabilize a beating heart to enable a beating heart ablation procedure. Many of the devices may be introduced into a patient via minimally invasive introducer devices and the like. Although devices and methods of the invention may be used to ablate epicardial tissue to treat atrial fibrillation, they may also be used in veterinary or research contexts, to treat various heart conditions other than atrial fibrillation and/or to ablate cardiac tissue other than the epicardium.
摘要翻译：装置和方法提供用于治疗心律失常的心脏组织的消融，例如心房颤动。虽然这些装置和方法通常用于消融至少一个肺静脉附近的心外膜组织，但是可以使用各种实施例来消融心脏上其他位置的其他心脏组织。装置通常包括用于接触心外膜组织并将消融装置固定到心外膜组织的至少一个组织接触构件以及用于烧蚀组织的至少一个消融构件。各种实施例包括诸如抽吸孔的特征，其使得装置能够以足够的强度附着到心外膜表面，以允许组织通过装置稳定。例如，一些实施例可用于稳定跳动心脏以实现搏动心脏消融手术。可以通过微创导引器装置等将许多装置引入患者体内。尽管本发明的装置和方法可用于消融心外膜组织以治疗房颤，但它们也可用于兽医学或研究领域，以治疗心房颤动以外的各种心脏病和/或除心外膜外的心脏组织。

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