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1. 发明申请

US20070237876A1 Production of Very Long Chain Polyunsaturated Fatty Acids in Oilseed Plants 审中-公开
标题翻译：在油菜植物中生产超长链多不饱和脂肪酸
公开(公告)号：US20070237876A1
公开(公告)日：2007-10-11
申请号：US11624777
申请日：2007-01-19
申请人： Anthony Kinney , Edgar Cahoon , Howard Damude , William Hitz , Zhan-Bin Liu , Charles Kolar
发明人： Anthony Kinney , Edgar Cahoon , Howard Damude , William Hitz , Zhan-Bin Liu , Charles Kolar
IPC分类号： A01H5/00 , A01H5/10 , A23D7/00 , A23L2/38 , C11B11/00
CPC分类号： C12N9/0083 , A21D2/165 , A23D9/00 , A23K20/158 , A23K50/40 , A23K50/80 , A23L11/01 , A23L11/03 , A23L11/05 , A23L11/07 , A23L33/12 , A23V2002/00 , A23V2300/21 , C12N9/1029 , C12N15/8247 , Y02A40/818 , A23V2250/1876 , A23V2250/1882
摘要： Oilseed plants which have been transformed to produce very long chain polyunsaturated fatty acids, recombinant constructs used in such transformations, methods for producing such fatty acids in a plant are described and uses of oils and seeds obtained from such transformed plants in a variety of food and feed applications are described.
摘要翻译：已经转化以产生非常长链多不饱和脂肪酸的油籽植物，用于这种转化的重组构建体，在植物中生产这种脂肪酸的方法，以及从这些转化植物获得的油和种子在多种食物中的应用，以及描述饲料应用。

2. 发明申请

US20080010699A1 Lysophosphatidic acid acetyltransferases 失效
标题翻译：溶血磷脂酸乙酰转移酶
公开(公告)号：US20080010699A1
公开(公告)日：2008-01-10
申请号：US11820045
申请日：2007-06-18
申请人： Edgar Cahoon , Anthony Kinney , William Hitz , Kevin Ripp , Rebecca Cahoon
发明人： Edgar Cahoon , Anthony Kinney , William Hitz , Kevin Ripp , Rebecca Cahoon
IPC分类号： A01H1/00 , C07H21/02 , C07K2/00 , C12N7/00
CPC分类号： C12N9/1029 , C12N15/8247
摘要： An isolated nucleic acid fragment encoding an LPAAT isozyme is disclosed. Construction of a chimeric gene encoding all or a portion of the LPAAT isozyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the LPAAT isozyme in a transformed host cell is also disclosed.
摘要翻译：公开了编码LPAAT同功酶的分离的核酸片段。还公开了在正义或反义方向上编码全部或部分LPAAT同功酶的嵌合基因的构建，其中嵌合基因的表达导致转化的宿主细胞中LPAAT同功酶水平的改变水平的产生。

3. 发明申请

US20060003430A1 Lysophosphatidic acit acetyltransferases 失效
标题翻译：溶血磷脂酰乙酰转移酶
公开(公告)号：US20060003430A1
公开(公告)日：2006-01-05
申请号：US11009658
申请日：2004-12-10
申请人： Edgar Cahoon , Anthony Kinney , William Hitz , Kevin Ripp , Rebecca Cahoon
发明人： Edgar Cahoon , Anthony Kinney , William Hitz , Kevin Ripp , Rebecca Cahoon
IPC分类号： C12N9/10 , C07H21/04 , C12P21/06 , C12N5/04
CPC分类号： C12N9/1029 , C12N15/8247
摘要： An isolated nucleic acid fragment encoding an LPAAT isozyme is disclosed. Construction of a chimeric gene encoding all or a portion of the LPAAT isozyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the LPAAT isozyme in a transformed host cell is also disclosed.
摘要翻译：公开了编码LPAAT同功酶的分离的核酸片段。还公开了在正义或反义方向上编码全部或部分LPAAT同功酶的嵌合基因的构建，其中嵌合基因的表达导致转化的宿主细胞中LPAAT同功酶水平的改变水平的产生。

4. 发明申请

US20050066390A1 Nucleotide sequences of a new class of diverged delta-9 stearoyl-ACP desaturase genes 失效
标题翻译：一类新型差异的δ-9硬脂酰-ACP去饱和酶基因的核苷酸序列
公开(公告)号：US20050066390A1
公开(公告)日：2005-03-24
申请号：US10981293
申请日：2004-11-04
申请人： John Booth , Rebecca Cahoon , William Hitz , Anthony Kinney , Narendra Yadav
发明人： John Booth , Rebecca Cahoon , William Hitz , Anthony Kinney , Narendra Yadav
IPC分类号： C12N9/02 , C12N15/53 , A01H1/00 , C07H21/04 , C12N5/04 , C12N9/04 , C12N15/82 , C12Q1/68
CPC分类号： C12N9/0083
摘要： An isolated nucleic acid fragment encoding a diverged delta-9 fatty acid desaturase is disclosed. Also the construction of a chimeric gene encoding all or a portion of the diverged delta-9 fatty acid desaturase is disclosed, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the diverged delta-9 fatty acid desaturase in a transformed host cell.
摘要翻译：公开了一种编码发散的δ-9脂肪酸去饱和酶的分离的核酸片段。在正义或反义方向上也公开了编码全部或部分分歧的δ-9脂肪酸去饱和酶的嵌合基因的构建，其中嵌合基因的表达导致产生改变的发散的δ-9脂肪酸水平去饱和酶在转化的宿主细胞中。

5. 发明申请

US20050282278A1 Plant sugar transport proteins 失效
标题翻译：植物糖转运蛋白
公开(公告)号：US20050282278A1
公开(公告)日：2005-12-22
申请号：US11210316
申请日：2005-08-24
申请人： Stephen Allen , William Hitz , Anthony Kinney , Scott Tingey
发明人： Stephen Allen , William Hitz , Anthony Kinney , Scott Tingey
IPC分类号： C07K14/415 , C12N15/29 , C12N15/82
CPC分类号： C07K14/415 , C12N15/8245
摘要： This invention relates to an isolated nucleic acid fragment encoding a sugar transport protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the sugar transport protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the sugar transport protein in a transformed host cell.
摘要翻译：本发明涉及编码糖转运蛋白的分离的核酸片段。本发明还涉及在正义或反义方向上构建编码全部或部分糖转运蛋白的嵌合基因，其中嵌合基因的表达导致转化的宿主细胞中糖转运蛋白的水平的改变。

6. 发明申请

US20050164269A1 Phytic acid biosynthetic enzymes 有权
公开(公告)号：US20050164269A1
公开(公告)日：2005-07-28
申请号：US11038329
申请日：2005-01-18
申请人： Rebecca Cahoon , William Hitz , Richard Pearlstein , Thomas Charlson
发明人： Rebecca Cahoon , William Hitz , Richard Pearlstein , Thomas Charlson
IPC分类号： C12N9/12 , C12N9/16 , C12N15/54 , C12N15/55 , C12N15/82 , C12Q1/68 , C07H21/04
CPC分类号： C12N9/1205 , C12N9/16 , C12N15/8243
摘要： This invention relates to an isolated nucleic acid fragment encoding a phytic acid biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the phytic acid biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the phytic acid biosynthetic enzyme in a transformed host cell.

7. 发明申请

US20060252139A1 Production of polyhydroxyalkanoate in plants 有权
公开(公告)号：US20060252139A1
公开(公告)日：2006-11-09
申请号：US11487811
申请日：2006-07-17
申请人： Kanwarpal Dhugga , Chun Li , Jian Dong , William Hitz , Matthias Liebergesell , Scott Nichols , Kristen Briggs
发明人： Kanwarpal Dhugga , Chun Li , Jian Dong , William Hitz , Matthias Liebergesell , Scott Nichols , Kristen Briggs
IPC分类号： C12N9/18
CPC分类号： C12N9/0006 , C12N9/00 , C12N9/88 , C12N15/52 , C12N15/8243 , C12N15/8247 , C12P7/625
摘要： The invention relates to the genetic manipulation of plants to produce polyhydroxyalkanoate, particularly in the peroxisomes. Methods for producing such polymers in plants and host cells are provided. Such methods find use in producing biodegradable thermoplastics in plants and other organisms. Nucleotide molecules, expression cassettes, and genetically manipulated host cell, plants, plant tissues, and seeds are also provided.

8. 发明申请

US20070130653A1 Methods and compositions for gene silencing 审中-公开
标题翻译：用于基因沉默的方法和组合物
公开(公告)号：US20070130653A1
公开(公告)日：2007-06-07
申请号：US11455073
申请日：2006-06-16
申请人： David Baulcombe , Enno Krebbers , William Hitz , Kimberly Glassman , Milo Aukerman , Robert Williams , Byung-Chun Yoo
发明人： David Baulcombe , Enno Krebbers , William Hitz , Kimberly Glassman , Milo Aukerman , Robert Williams , Byung-Chun Yoo
IPC分类号： A01H1/00 , C07H21/02 , C12N15/82 , C07H21/04 , C12N5/04
CPC分类号： C12N15/8218 , C07H21/02 , C07H21/04 , C12N2310/14
摘要： Methods and compositions are provided for reducing the level of expression of a target polynucleotide in an organism. The methods and compositions selectively silence the target polynucleotide through the expression of a chimeric polynucleotide comprising the target for a sRNA (the trigger sequence) operably linked to a sequence corresponding to all or part of the gene or genes to be silenced. In this manner, the final target of silencing is an endogenous gene in the organism in which the chimeric polynucleotide is expressed. In a further embodiment, the miRNA target is that of a heterologous miRNA or siRNA, the latter of which is coexpressed in the cells at the appropriate developmental stage to provide silencing of the final target when and where desired. In a further embodiment, the final target may be a gene in a second organism, such as a plant pest, that feeds upon the organism containing the chimeric gene or genes. Compositions further comprise vectors, seeds, grain, cells, and organisms, including plants and plant cells, comprising the chimeric polynucleotide of the invention.
摘要翻译：提供了用于降低生物体中靶多核苷酸表达水平的方法和组合物。所述方法和组合物通过表达嵌合多核苷酸来选择性沉默靶多核苷酸，所述嵌合多核苷酸包含可操作地连接到对应于待沉默的基因或基因的全部或部分的序列的sRNA（触发序列）的靶。以这种方式，沉默的最终靶标是其中表达嵌合多核苷酸的生物体中的内源基因。在另一个实施方案中，miRNA靶是异源miRNA或siRNA的靶标，其后者在合适的发育阶段在细胞中共表达，以在需要时和期望时提供最终靶的沉默。在另一个实施方案中，最终靶可以是在含有嵌合基因或基因的生物体上进食的第二生物体如植物害虫中的基因。组合物还包含载体，种子，谷粒，细胞和生物，包括植物和植物细胞，其包含本发明的嵌合多核苷酸。

9. 发明申请

US20060260006A1 Production of polyhydroxyalkanoate in plants 审中-公开
公开(公告)号：US20060260006A1
公开(公告)日：2006-11-16
申请号：US11487852
申请日：2006-07-17
申请人： Kanwarpal Dhugga , Chun Li , Jian Dong , William Hitz , Matthias Liebergesell , Scott Nichols , Kristen Briggs
发明人： Kanwarpal Dhugga , Chun Li , Jian Dong , William Hitz , Matthias Liebergesell , Scott Nichols , Kristen Briggs
IPC分类号： A01H1/00 , C12N15/87
CPC分类号： C12N15/8243
摘要： The invention relates to the genetic manipulation of plants to produce polyhydroxyalkanoate, particularly in the peroxisomes. Methods for producing such polymers in plants and host cells are provided. Such methods find use in producing biodegradable thermoplastics in plants and other organisms. Nucleotide molecules, expression cassettes, and genetically manipulated host cell, plants, plant tissues, and seeds are also provided.

10. 发明申请

US20060137040A1 Canola oil having increased oleic acid and decreased linolenic acid content 有权
公开(公告)号：US20060137040A1
公开(公告)日：2006-06-22
申请号：US11340318
申请日：2006-01-26
申请人： Lorin DeBonte , William Hitz
发明人： Lorin DeBonte , William Hitz
IPC分类号： A01H5/00 , A01H1/00 , C12N15/82 , C11B1/00
CPC分类号： C12N9/0083 , A01H5/10 , A23D9/00 , C11B1/10 , C12N15/8218 , C12N15/8247
摘要： An endogenous oil extracted from Brassica seeds is disclosed that contains, after crushing and extraction, greater than 86% oleic acid and less than 2.5% α-linolenic acid. The oil also contains less than 7% linoleic acid. The Brassica seeds are produced by plants that contain seed-specific inhibition of microsomal oleate desaturase and microsomal linoleate desaturase gene expression. Such inhibition can be created by cosuppression or antisense technology. Such an oil has a very high oxidative stability in the absence of added antioxidants.

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