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1. 发明申请

US20060199259A1 Instrument for monitoring DNA replication 有权
标题翻译：用于监测DNA复制的仪器
公开(公告)号：US20060199259A1
公开(公告)日：2006-09-07
申请号：US11406148
申请日：2006-04-18
申请人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Susan Stone , Judith Atwood , John Atwood
发明人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Susan Stone , Judith Atwood , John Atwood
IPC分类号： C12M1/34
CPC分类号： G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
摘要： An instrument for monitoring replication of DNA is provided.
摘要翻译：提供了一种用于监测DNA复制的工具。

2. 发明申请

US20070154939A1 Instrument for monitoring polymerase chain reaction of DNA 审中-公开
标题翻译：监测DNA聚合酶链反应的仪器
公开(公告)号：US20070154939A1
公开(公告)日：2007-07-05
申请号：US11711416
申请日：2007-02-26
申请人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , John Atwood , Susan Stone , Judith Atwood
发明人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , John Atwood , Susan Stone , Judith Atwood
IPC分类号： C12Q1/68 , G06F19/00 , C12M3/00
CPC分类号： G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
摘要： An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.
摘要翻译：光学仪器监测具有温度循环阻滞的反应装置中DNA的PCR复制，所述反应装置具有小瓶的反应成分，包括在双链DNA存在下发荧光的染料。分束器将激发光束传递到小瓶以使染料发荧光。来自染料的发射光束通过分束器传递到CCD检测器，处理器从该CCD检测器计算DNA浓度。具有多个参考发射器的参考条发射不同强度的参考光束，处理器从该参考光束选择用于补偿漂移的最佳发射器。自动调整曝光时间以保持CCD和处理器的最佳动态范围。分束器和相关的滤光器的模块与选定的染料相关联，并且可替代不同的染料。

3. 发明申请

US20070148761A1 Instrument for monitoring polymerase chain reaction of DNA 审中-公开
标题翻译：监测DNA聚合酶链反应的仪器
公开(公告)号：US20070148761A1
公开(公告)日：2007-06-28
申请号：US11705856
申请日：2007-02-13
申请人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Judith Atwood , John Atwood , Susan Stone
发明人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Judith Atwood , John Atwood , Susan Stone
IPC分类号： C12M1/34
CPC分类号： G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
摘要： An optical instrument monitors PCR replication of DNA in a reaction apparatus having vials of reaction ingredients. A beam splitter passes an excitation beam to the vials. An emission beam from the reaction ingredients can be passed by the beam splitter to a detector from which a processor can compute DNA concentration. A reference strip with a plurality of reference emitters can be provided which emits reference beams of different intensity, from which the processor can select an optimum emitter for compensating for drift. Exposure time can be automatically adjusted for keeping within optimum dynamic ranges of the detector and processor. A module of the beam splitter and associated optical filters can be associated with a selected dye, and can be replaceable for different dyes.
摘要翻译：光学仪器在具有小瓶反应成分的反应设备中监测DNA的PCR复制。分束器将激发光束传递到小瓶。来自反应成分的发射光束可以通过分光器传递到检测器，处理器可以从该分光器计算DNA浓度。可以提供具有多个参考发射器的参考条，其发射不同强度的参考光束，处理器可以从其中选择用于补偿漂移的最佳发射器。曝光时间可以自动调整，以保持在检测器和处理器的最佳动态范围内。分束器和相关联的滤光器的模块可以与所选择的染料相关联，并且可以替代不同的染料。

4. 发明申请

US20070238161A1 Instrument for monitoring polymerase chain reaction of DNA 有权
公开(公告)号：US20070238161A1
公开(公告)日：2007-10-11
申请号：US11804151
申请日：2007-05-17
申请人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Susan Stone , Judith Atwood
发明人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Susan Stone , Judith Atwood
IPC分类号： C12M1/34 , C12M1/36
CPC分类号： G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/0303 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
摘要： An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.

5. 发明申请

US20060128009A1 Instrument for monitoring polymerase chain reaction of DNA 有权
公开(公告)号：US20060128009A1
公开(公告)日：2006-06-15
申请号：US11333483
申请日：2006-01-17
申请人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Susan Stone , Judith Atwood
发明人： Anthony Cerrone , Edward Lakatos , Michael Gambini , Eugene Young , Susan Stone , Judith Atwood
IPC分类号： C12M1/34
CPC分类号： G01N21/6428 , B01L3/5085 , B01L7/52 , B01L2200/10 , B01L2300/0654 , B01L2300/0663 , B01L2300/1811 , C12Q1/686 , C12Q2545/101 , G01N21/274 , G01N21/645 , G01N21/6452 , G01N2021/6419 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6463 , G01N2021/6482 , G01N2201/0245 , G01N2201/06113 , G01N2201/0628 , G01N2201/0635 , G01N2201/0636 , G01N2201/068 , C12Q2563/107
摘要： An optical instrument monitors PCR replication of DNA in a reaction apparatus having a temperature cycled block with vials of reaction ingredients including dye that fluoresces in presence of double-stranded DNA. A beam splitter passes an excitation beam to the vials to fluoresce the dye. An emission beam from the dye is passed by the beam splitter to a CCD detector from which a processor computes DNA concentration. A reference strip with a plurality of reference emitters emit reference beams of different intensity, from which the processor selects an optimum emitter for compensating for drift. Exposure time is automatically adjusted for keeping within optimum dynamic ranges of the CCD and processor. A module of the beam splitter and associated optical filters is associated with selected dye, and is replaceable for different dyes.

6. 发明授权

US08696731B2 Lock/floating marker band on pusher wire for self-expanding stents or medical devices 有权
标题翻译：用于自扩张支架或医疗器械的推动线上的锁定/浮动标记带
公开(公告)号：US08696731B2
公开(公告)日：2014-04-15
申请号：US13158223
申请日：2011-06-10
申请人： Eugene Young , Chung Hao Yeh , Christopher G. M. Ken , Thu Anh Ho
发明人： Eugene Young , Chung Hao Yeh , Christopher G. M. Ken , Thu Anh Ho
IPC分类号： A61F2/06 , A61B17/00
CPC分类号： A61F2/95 , A61F2002/9528 , A61F2002/9665 , A61F2250/0098
摘要： An apparatus for deploying and retrieving a self-expanding intravascular stent includes an intravascular delivery wire and floating marker band movably retained over the intravascular stent delivery wire and releasably mounting the self-expanding intravascular stent. The floating marker band is movably retained to a fixed marker band, and a distance between the fixed marker band and the floating marker band is variable and self-adjusting. One or more struts of the self-expanding intravascular stent are releasably constrained between a catheter wall and one or more sides of the floating marker band.
摘要翻译：用于展开和取回自扩张血管内支架的装置包括可移动地保持在血管内支架输送线上的血管内输送线和浮动标记带，并可释放地安装自膨胀血管内支架。浮动标记带可移动地保持在固定标记带上，并且固定标记带和浮动标记带之间的距离是可变的并且是自调整的。自膨胀血管内支架的一个或多个支柱可释放地约束在导管壁与浮动标记带的一侧或多侧之间。

7. 发明申请

US20090210046A1 HANDLE ASSEMBLY FOR A DELIVERY SYSTEM 审中-公开
标题翻译：手提装置用于送货系统
公开(公告)号：US20090210046A1
公开(公告)日：2009-08-20
申请号：US12034080
申请日：2008-02-20
申请人： Daniel H. Shumer , Karim S. Osman , Eugene Young , Leopoldo Ortega
发明人： Daniel H. Shumer , Karim S. Osman , Eugene Young , Leopoldo Ortega
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2002/9517
摘要： A delivery system incorporating a belt for accomplishing relative movement between components of the system. In one aspect, a handle assembly of the delivery system includes a trigger as well as a thumbwheel assembly each configured to activate longitudinal movement of the belt.
摘要翻译：一种输送系统，其包括用于实现系统的部件之间的相对运动的带。在一个方面，输送系统的手柄组件包括触发器以及指轮组件，每个配置用于激活皮带的纵向移动。

8. 发明申请

US20090005858A1 INTEGRATION OF MARKERS INTO BAR ARMS USING A WARM-FORMING PROCESS 审中-公开
标题翻译：使用温度成形过程将标记集成到棒状结构中
公开(公告)号：US20090005858A1
公开(公告)日：2009-01-01
申请号：US12103440
申请日：2008-04-15
申请人： Eugene Young , Sanjay Shrivastava , Russ Borg , Daniel H. Shumer , Mark Weiss , Philip Simeon , Karim Osman
发明人： Eugene Young , Sanjay Shrivastava , Russ Borg , Daniel H. Shumer , Mark Weiss , Philip Simeon , Karim Osman
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91558 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2250/0098
摘要： A stent having a body capable of visualization under X-ray fluoroscopic techniques. The stent body includes radiopaque strut members. The stent body can also have a radiopacity gradient along the length of the stent body.
摘要翻译：具有能够在X射线透视技术下可视化的主体的支架。支架主体包括不透射线的支柱构件。支架主体还可以具有沿支架主体长度的不透射线梯度。

9. 发明申请

US20050107865A1 Endoprosthesis having foot extensions 有权
标题翻译：具有脚伸展的内假体
公开(公告)号：US20050107865A1
公开(公告)日：2005-05-19
申请号：US10992976
申请日：2004-11-19
申请人： Anton Clifford , Kevin Kang , David Lowe , Jeff Pappas , Erik Eli , Howard Huang , Lisa Weldon , Ketan Muni , Eugene Young
发明人： Anton Clifford , Kevin Kang , David Lowe , Jeff Pappas , Erik Eli , Howard Huang , Lisa Weldon , Ketan Muni , Eugene Young
IPC分类号： A61F2/00 , A61F2/06 , A61F2/90
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2220/0008 , A61F2230/0054 , A61F2250/0098 , Y10T29/49826 , Y10T29/49908
摘要： Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration. The annular elements are longitudinally aligned and connected at connection locations. Preferably, each connection location includes a foot extension, such as by an overlapping pattern between the longitudinally-adjacent annular elements or by a connector extending therebetween.
摘要翻译：内置假体，例如支架，包括至少一个环形元件，所述至少一个环形元件由第一组支柱构件限定，所述第一组撑杆构件互相连接以限定靠近所述环形元件相对侧的顶点。环形元件还包括在至少一对周向相邻的支柱构件之间延伸的脚延伸部。脚部延伸部具有从周向相邻的支柱构件的对应端部周向延伸的第一和第二脚部，并且具有轮廓以提供至少两个弯曲区域。第一和第二脚部在脚延伸部的脚趾部分处连接，并且在一对周向相邻的支柱构件之间限定圆周方向的顶点。优选地，提供至少一个或多个另外的环形元件，每个环形元件由互连的支柱构件限定。环形元件通常在输送配置和展开配置之间可扩展。环形元件在连接位置处纵向对齐并连接。优选地，每个连接位置包括脚部延伸部，例如通过在纵向相邻的环形元件之间的重叠图案，或者通过在它们之间延伸的连接器。

10. 发明申请

US20120316636A1 LOCK/FLOATING MARKER BAND ON PUSHER WIRE FOR SELF-EXPANDING STENTS OR MEDICAL DEVICES 有权
标题翻译：用于自扩张式手术或医疗器械的推杆上的锁定/浮动标记带
公开(公告)号：US20120316636A1
公开(公告)日：2012-12-13
申请号：US13158223
申请日：2011-06-10
申请人： Eugene Young , Chung Hao Yeh , Christopher G.M. Ken , Thu Anh Ho
发明人： Eugene Young , Chung Hao Yeh , Christopher G.M. Ken , Thu Anh Ho
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2002/9528 , A61F2002/9665 , A61F2250/0098
摘要： An apparatus for deploying and retrieving a self-expanding intravascular stent includes an intravascular delivery wire and floating marker band movably retained over the intravascular stent delivery wire and releasably mounting the self-expanding intravascular stent. The floating marker band is movably retained to a fixed marker band, and a distance between the fixed marker band and the floating marker band is variable and self-adjusting. One or more struts of the self-expanding intravascular stent are releasably constrained between a catheter wall and one or more sides of the floating marker band.
摘要翻译：用于展开和取回自扩张血管内支架的装置包括可移动地保持在血管内支架输送线上的血管内输送线和浮动标记带，并可释放地安装自扩张血管内支架。浮动标记带可移动地保持在固定标记带上，并且固定标记带和浮动标记带之间的距离是可变的并且是自调整的。自膨胀血管内支架的一个或多个支柱可释放地约束在导管壁与浮动标记带的一侧或多侧之间。

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