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1. 发明授权

US07953615B2 System and method of administering, tracking and managing of claims processing 有权
标题翻译：管理，跟踪和管理索赔处理的制度和方法
公开(公告)号：US07953615B2
公开(公告)日：2011-05-31
申请号：US09825604
申请日：2001-04-03
申请人： Anthony Aquila , Edward L Schrenk , Patrick Cole , Thomas Lyons , David Griffin , Mike Marsh , Hassold Christian , Frederick C Fisher , Carlos Portal
发明人： Anthony Aquila , Edward L Schrenk , Patrick Cole , Thomas Lyons , David Griffin , Mike Marsh , Hassold Christian , Frederick C Fisher , Carlos Portal
IPC分类号： G06Q10/00 , G06Q50/00 , A61B5/00 , G06F19/00 , G06Q40/00
CPC分类号： G06Q40/02 , G06F19/00 , G06Q40/08 , G06Q50/22 , G06Q50/24
摘要： A system and method of administering, tracking and managing of claims processing.
摘要翻译：管理，跟踪和管理索赔处理的系统和方法。

2. 发明申请

US20120029946A1 SYSTEM AND METHOD OF ADMINISTERING, TRACKING AND MANAGING OF CLAIMS PROCESSING 审中-公开
标题翻译：管理，跟踪和管理索赔处理的系统和方法
公开(公告)号：US20120029946A1
公开(公告)日：2012-02-02
申请号：US13118266
申请日：2011-05-27
申请人： Anthony Aquila , Edward L. Schrenk , Patrick Cole , Thomas Lyons , David Griffin , Mike Marsh , Christian Hassold , Frederick C. Fisher , Carlos Portal
发明人： Anthony Aquila , Edward L. Schrenk , Patrick Cole , Thomas Lyons , David Griffin , Mike Marsh , Christian Hassold , Frederick C. Fisher , Carlos Portal
IPC分类号： G06Q40/00
CPC分类号： G06Q40/02 , G06Q40/08 , G06Q50/22 , G06Q50/24
摘要： A system and method of administering, tracking and managing of claims processing.
摘要翻译：管理，跟踪和管理索赔处理的系统和方法。

3. 发明授权

US08809001B2 High throughput assays for inhibitors and activators of PAQR receptors 有权
标题翻译：抑制剂和PAQR受体激活剂的高通量测定
公开(公告)号：US08809001B2
公开(公告)日：2014-08-19
申请号：US12679753
申请日：2008-09-23
申请人： Thomas Lyons , Brian R. Kupchak , Jessica L. Smith , Ibon Garitaonandia
发明人： Thomas Lyons , Brian R. Kupchak , Jessica L. Smith , Ibon Garitaonandia
IPC分类号： G01N33/53 , C12Q1/54 , C12Q1/02 , G01N33/566 , C07K14/72
CPC分类号： G01N33/566 , C07K14/72 , G01N2333/723 , G01N2500/10
摘要： The subject invention provides methods of screening compounds or ligands that interact with human and/or non-human PAQR receptors or fungal osmotin receptors. These methods utilize a colorimetric assay to ascertain whether a compound binds to and activates a PAQR receptor or the osmotin receptor.
摘要翻译：本发明提供了筛选与人和/或非人类PAQR受体或真菌渗透素受体相互作用的化合物或配体的方法。这些方法利用比色测定来确定化合物是否结合并激活PAQR受体或氧化蛋白受体。

4. 发明申请

US20060062879A1 Dough rolling apparatus and method 有权
标题翻译：面团轧制装置及方法
公开(公告)号：US20060062879A1
公开(公告)日：2006-03-23
申请号：US10946831
申请日：2004-09-22
申请人： Marlin Anderson , David Barry , David Emerson , William Flannigan , John Kiel , Geoffrey Ley , Thomas Lyons , Richard Ruegg
发明人： Marlin Anderson , David Barry , David Emerson , William Flannigan , John Kiel , Geoffrey Ley , Thomas Lyons , Richard Ruegg
IPC分类号： A21D6/00
CPC分类号： A21C3/06 , A21C11/10
摘要： An improved dough-rolling apparatus and method for rolling sheeted dough. The proposed invention comprises a dough-rolling apparatus having a dough sheeter, a sheeting conveyor having a ramped section, a roll-initiating curtain positioned above the ramped section, and a roll-completing curtain positioned above the conveyor and downstream from the roll-initiating conveyor. Sheeted and cut dough pieces are deposited onto a steel mesh, partially-ramped sheeter belt, where two wire-mesh rolling curtains are draped onto the sheeter belt to induce rolling of the dough pieces.
摘要翻译：一种改进的面团轧制设备和用于轧制生面团的方法。所提出的发明包括具有面团片材的面团轧制设备，具有倾斜部分的片材输送机，位于倾斜部分上方的卷起始帘幕，以及位于输送机上方并且在卷起始位置的下游的卷帘幕输送带。将成片和切割的面团片沉积到钢网，部分斜坡的折页机上，其中两个丝网卷帘被覆在片材带上以引起面片的滚动。

5. 发明申请

US20080004255A1 Methods and compositions for altering cell function 审中-公开
公开(公告)号：US20080004255A1
公开(公告)日：2008-01-03
申请号：US11581682
申请日：2006-10-16
申请人： Thomas Lyons , Ronan Power
发明人： Thomas Lyons , Ronan Power
IPC分类号： A61K31/095 , A61K31/13 , A61K31/136 , A61K31/198 , A61K31/355 , A61K31/385 , A61K31/41 , A61K31/433 , A61K31/445 , A61K31/47 , A61K31/473 , A61K31/55 , A61P25/28
CPC分类号： A61K31/095 , A61K31/13 , A61K31/136 , A61K31/198 , A61K31/355 , A61K31/385 , A61K31/41 , A61K31/433 , A61K31/445 , A61K31/47 , A61K31/473 , A61K31/55
摘要： The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment for neurodegenerative disease). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX) possess the ability to alter expression of genes associated with disease and/or aging while other forms of selenium (e.g., selenomethionine) do not.

6. 发明申请

US20060063121A1 Containment apparatus for multi-pass ovens 有权
标题翻译：多道烤箱的容器装置
公开(公告)号：US20060063121A1
公开(公告)日：2006-03-23
申请号：US10946835
申请日：2004-09-22
申请人： David Barry , David Emerson , William Flannigan , John Kiel , Geoffrey Ley , Thomas Lyons , Devang Sutaria
发明人： David Barry , David Emerson , William Flannigan , John Kiel , Geoffrey Ley , Thomas Lyons , Devang Sutaria
IPC分类号： F27B9/26
CPC分类号： A21B1/48
摘要： A containment apparatus for a multi-pass oven consisting of guide rails and tapered guide chutes having side rails. A tapered guide chute directs product pieces from one conveyor to the center of a receiving region of an underlying conveyor. Guide rails are placed along the sides of the receiving region of an underlying conveyor and maintain baking product pieces on the conveyor. Diverters on the distal end of each guide rail further move product pieces toward the center of the conveyor. Such diverters help ensure that pieces reach a subsequent guide chute or subsequent conveyor without falling off of the conveyor. Such guide rails, diverters, and guide chutes help prevent damage to, and loss of, product pieces while pieces pass through the oven. Guide rails, diverters, and guide chutes are particularly effective at maintaining round or cylindrical pieces within a multi-pass oven.
摘要翻译：一种由导轨组成的多通道烘箱和具有侧轨的锥形导槽的容纳装置。锥形导槽将产品从一个输送机引导到下一个输送机的接收区域的中心。导轨沿着下层输送机的接收区域的侧面放置，并将烘焙产品块保持在输送机上。每个导轨的远端上的分流器进一步将产品朝向输送机的中心移动。这种分流器有助于确保碎片到达随后的导向槽或随后的输送机，而不会从输送机上脱落。这样的导轨，分流器和引导滑槽有助于防止碎片通过烤箱时产品损坏和损失。导轨，分流器和导向滑槽在多通道烘箱内保持圆形或圆柱形件是特别有效的。

7. 发明申请

US20100261178A1 High Throughput Assays for Inhibitors and Activators of PAQR Receptors 有权
标题翻译： PAQR受体抑制剂和活化剂的高通量测定
公开(公告)号：US20100261178A1
公开(公告)日：2010-10-14
申请号：US12679753
申请日：2008-09-23
申请人： Thomas Lyons , Brian R. Kupchak , Jessica L. Smith , Ibon Garitaonandia
发明人： Thomas Lyons , Brian R. Kupchak , Jessica L. Smith , Ibon Garitaonandia
IPC分类号： C12Q1/68 , G01N33/569
CPC分类号： G01N33/566 , C07K14/72 , G01N2333/723 , G01N2500/10
摘要： The subject invention provides methods of screening compounds or ligands that interact with human and/or non-human PAQR receptors or fungal osmotin receptors. These methods utilize a colorimetric assay to ascertain whether a compound binds to and activates a PAQR receptor or the osmotin receptor.
摘要翻译：本发明提供了筛选与人和/或非人类PAQR受体或真菌渗透素受体相互作用的化合物或配体的方法。这些方法利用比色测定来确定化合物是否结合并激活PAQR受体或氧化蛋白受体。

8. 发明申请

US20080107755A1 Methods and compositions for altering cell function 审中-公开
标题翻译：用于改变细胞功能的方法和组合物
公开(公告)号：US20080107755A1
公开(公告)日：2008-05-08
申请号：US11789275
申请日：2007-04-24
申请人： Thomas Lyons , Ronan Power
发明人： Thomas Lyons , Ronan Power
IPC分类号： A61K33/04 , A61P25/16 , A61P25/28
CPC分类号： A61K33/04
摘要： The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium).
摘要翻译：本发明涉及用于改变细胞功能的组合物和方法。特别地，本发明提供了包含硒（例如，SEL-PLEX）的组合物及其使用方法（例如，作为治疗和/或预防性治疗）。另外，本发明证明当施用于受试者时，具体形式的硒（例如，SEL-PLEX）具有改变（例如，降低）各种组织中的基因表达的能力（例如，与未施用的受试者的表达相比较）硒）。

9. 发明申请

US20080008692A1 Methods and compositions for altering cell function 有权
标题翻译：用于改变细胞功能的方法和组合物
公开(公告)号：US20080008692A1
公开(公告)日：2008-01-10
申请号：US11581243
申请日：2006-10-16
申请人： Thomas Lyons , Ronan Power
发明人： Thomas Lyons , Ronan Power
IPC分类号： A61K33/04 , A61K33/34 , A61K36/06 , A61P25/14 , A61P25/16 , A61P25/28
CPC分类号： A61K33/04 , A61K33/34 , A61K36/06 , A61K45/06
摘要： The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment for neurodegenerative disease). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX) possess the ability to alter expression of genes associated with disease and/or aging while other forms of selenium (e.g., selenomethionine) do not.
摘要翻译：本发明涉及用于改变细胞功能的组合物和方法。特别地，本发明提供了包含硒（例如SEL-PLEX）的组合物及其使用方法（例如，作为神经变性疾病的治疗和/或预防性治疗）。另外，本发明证明硒的特定形式（例如，SEL-PLEX）具有改变与疾病和/或衰老相关基因表达的能力，而其他形式的硒（例如硒代甲硫氨酸）不具有这种能力。

10. 发明申请

US20070155687A1 Methods and compositions for altering cell function 审中-公开
公开(公告)号：US20070155687A1
公开(公告)日：2007-07-05
申请号：US11581535
申请日：2006-10-16
申请人： Thomas Lyons , Ronan Power
发明人： Thomas Lyons , Ronan Power
IPC分类号： A61K48/00 , A61K31/198 , A61K31/433 , A61K31/4704 , A61K31/473 , A61K31/445 , A61K31/55 , A61K31/355 , A61K31/375 , A61K31/135 , A61K31/13 , A61K31/095
CPC分类号： C12N15/63 , A61K33/04 , A61K45/06
摘要： The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL-PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment for neurodegenerative disease). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX) possess the ability to alter expression of genes associated with disease and/or aging while other forms of selenium (e.g., selenomethionine) do not.

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