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1. 发明授权

US06548492B1 Process for formulation of carbapenem antibiotic compositions 有权
标题翻译：碳青霉烯类抗生素组合物的制备方法
公开(公告)号：US06548492B1
公开(公告)日：2003-04-15
申请号：US09698808
申请日：2000-10-27
申请人： Anthony Al-Dehneh , William A. Hunke , Kathleen J. Illig , Anand Kanike , Hiren Patel , Scott D. Reynolds , Stelios C. Tsinontides
发明人： Anthony Al-Dehneh , William A. Hunke , Kathleen J. Illig , Anand Kanike , Hiren Patel , Scott D. Reynolds , Stelios C. Tsinontides
IPC分类号： C07D48704
CPC分类号： C07D477/20 , A61K31/40 , A61K31/407 , C07D477/02
摘要： A novel process for preparing a stabilized, lyophilized carbapenem, antibiotic formulation suitable for intravenous administration to patients in need thereof, wherein the active ingredient is of formula II: The process entails compounding a unstable, monosodium salt carbapenem with a sodium bicarbonate solution at a temperature range of from about 0° to about 5° C. while maintaining a pH between about 7.0 and about 8.0, filtering the resultant solution, bottling under sterile conditions, and lyophilizing to produce the formulation.
摘要翻译：一种用于制备稳定的冻干碳青霉烯类抗生素制剂的新方法，其适用于需要其的患者的静脉内施用，其中活性成分为式II：该方法需要将不稳定的单钠盐碳青霉烯类与碳酸氢钠溶液在温度范围为约0℃至约5℃，同时保持pH在约7.0至约8.0之间，过滤所得溶液，在无菌条件下装瓶，并冻干以制备制剂。

2. 发明申请

US20080008162A1 Method and system for network path discrimination 审中-公开
标题翻译：网络路径辨别的方法和系统
公开(公告)号：US20080008162A1
公开(公告)日：2008-01-10
申请号：US11819625
申请日：2007-06-28
申请人： Jose Martinez , Hiren Patel
发明人： Jose Martinez , Hiren Patel
IPC分类号： H04L12/66
CPC分类号： H04L45/22 , H04L45/12
摘要： A system and method for provisionable, multi-modal communications, including detecting a provisioning condition, selecting a communications mode based on the provisioning condition from a first usage mode, a second usage mode, and a third usage mode, and displaying an interface corresponding to the selected communications mode. The first usage mode includes a first communications channel supporting a first communication data consisting of instant messages (IM) and in-network voice data. The second usage mode includes a second communications channel supporting a second communication data consisting of IM, in-network voice data and out-of-network voice data. The third usage mode includes a second communications channel supporting a third communication data comprising video data.
摘要翻译：一种用于可配置的多模式通信的系统和方法，包括检测供应条件，基于来自第一使用模式，第二使用模式和第三使用模式的供应条件选择通信模式，并且显示对应于所选择的通信模式。第一使用模式包括支持由即时消息（IM）和网络内语音数据组成的第一通信数据的第一通信信道。第二使用模式包括支持由IM，网络内语音数据和网络外语音数据组成的第二通信数据的第二通信信道。第三使用模式包括支持包括视频数据的第三通信数据的第二通信信道。

3. 发明授权

US06458957B1 &agr;,&agr;-dibromo-&agr;-chloro-acetophenones as synthons 有权
标题翻译： α，α-二溴-α-氯 - 苯乙酮作为合成子
公开(公告)号：US06458957B1
公开(公告)日：2002-10-01
申请号：US09614295
申请日：2000-07-12
申请人： Anup K. Ray , Hiren Patel , Shilpa V. Merai , Mahendra R. Patel
发明人： Anup K. Ray , Hiren Patel , Shilpa V. Merai , Mahendra R. Patel
IPC分类号： C07D21126
CPC分类号： C07D213/74 , C07C45/46 , C07C45/63 , C07C49/80 , C07C49/813 , C07C49/84 , C07C67/00 , C07C67/343 , C07C231/10 , C07D211/26 , C07D295/182 , C07C69/92 , C07C69/738 , C07C235/60
摘要： This disclosure relates to the use of &agr;,&agr;-dibromo-&agr;-chloroacetophenone compounds as intermediates for the preparation of aromatic carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2-trifluoroethoxy)-&agr;,&agr;-dibromo-&agr;-chloroacetophenone is especially useful as an intermediate for the preparation of flecainide, a known pharmaceutical.
摘要翻译：本公开涉及α，α-二溴-α-氯苯乙酮化合物作为制备芳族羰基化合物，特别是芳族酰胺的中间体的用途。化合物2,5-双（2,2,2-三氟乙氧基）-α，α-二溴-α-氯乙酰苯特别可用作制备已知药物的氟卡尼的中间体。

4. 发明申请

US20080139609A1 GRANISETRON COMPOSITIONS 审中-公开
标题翻译：格列本组合物
公开(公告)号：US20080139609A1
公开(公告)日：2008-06-12
申请号：US11936140
申请日：2007-11-07
申请人： Bikash Kumar Sahoo , Hiren Patel , Srinivas Irukulla , Indu Bhushan , Mailatur Sivaraman Mohan
发明人： Bikash Kumar Sahoo , Hiren Patel , Srinivas Irukulla , Indu Bhushan , Mailatur Sivaraman Mohan
IPC分类号： A61K31/439
CPC分类号： A61K31/439 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K9/2077 , A61K47/02 , A61K47/10 , A61K47/12
摘要： Stable liquid pharmaceutical compositions comprise granisetron or a pharmaceutically acceptable salt thereof.
摘要翻译：稳定的液体药物组合物包含格拉司琼或其药学上可接受的盐。

5. 发明申请

US20080107730A1 SUSTAINED RELEASE PHARMACEUTICAL PREPARATIONS AND METHODS FOR PRODUCING THE SAME 审中-公开
标题翻译：可持续发布药物制剂及其生产方法
公开(公告)号：US20080107730A1
公开(公告)日：2008-05-08
申请号：US11971741
申请日：2008-01-09
申请人： Davejibhai KUMBHANI , Harish Pandya , Hiren Patel
发明人： Davejibhai KUMBHANI , Harish Pandya , Hiren Patel
IPC分类号： A61K9/22 , A61K31/137
CPC分类号： A61K9/2886 , A61K9/2054 , A61K9/2866 , A61K31/137
摘要： An extended release tablet comprising a core including albuterol sulfate and extended release agent; and an extended release coating on the core to provide for sustained release of the albuterol sulfate.
摘要翻译：一种缓释片剂，其包含含有沙丁胺醇硫酸盐和延长释放剂的核心; 和核心上的延长释放包衣以提供硫酸沙丁胺醇的持续释放。

6. 发明申请

US20060105037A1 Sustained release pharmaceutical preparations and methods for producing the same 审中-公开
公开(公告)号：US20060105037A1
公开(公告)日：2006-05-18
申请号：US11332158
申请日：2006-01-17
申请人： Davejibhai Kumbhani , Harish Pandya , Hiren Patel
发明人： Davejibhai Kumbhani , Harish Pandya , Hiren Patel
IPC分类号： A61K9/22
CPC分类号： A61K9/2886 , A61K9/2054 , A61K9/2866 , A61K31/137
摘要： An extended release tablet comprising a core including albuterol sulfate and extended release agent; and an extended release coating on the core to provide for sustained release of the albuterol sulfate.

7. 发明授权

US06962924B2 Salt and polymorphs of desloratadine hemifumarate 失效
标题翻译：地氯雷他定半富马酸盐和多晶型物
公开(公告)号：US06962924B2
公开(公告)日：2005-11-08
申请号：US10621670
申请日：2003-07-17
申请人： Anup Kumar Ray , Hiren Patel , Mahendra R Patel
发明人： Anup Kumar Ray , Hiren Patel , Mahendra R Patel
IPC分类号： A61K31/4545 , A61P37/08 , A61P43/00 , C07D401/04 , A61K31/445 , C07D401/08
CPC分类号： C07D401/04
摘要： This invention provides a process of preparation of novel polymorphic hemifumarate salts of 8-chloro-6,11-dihyfro-11-(4-piperidylidene)-5H-benzo[5,6]-cyclohepta[1,2-b]pyridine, hereinafter called “desloratadine”. These polymorphic salt forms show much higher solubility in water and also in protic organic solvents compare to the parent desloratadine. The process of preparing the polymorphic forms comprising: a) mixing the ethanolic solution of desloratadine and fumaric acid at a temperature of from about 55° C. to 70° C., and stirring for 30 to 45 minutes after mixing, and thereafter filtering the solid thereby prepared in hot condition; to yield the polymorphic form 2 having a DSC of 232° C.±2° C.; or b) mixing the ethanolic solution of desloratadine and fumaric acid at a temperature of form about 15° C. room temperature (25° C.) and stirring at this temperature for 30 to 45 minutes, then filtering at room temperature; to yield the polymorphic form 1 having a DSC of 224° C.±2° C.
摘要翻译：本发明提供了8-氯-6,11-二氢-10-（4-哌啶基）-5H-苯并[5,6]环庚并[1,2-b]吡啶的新型多晶型富马酸盐的制备方法，以下称为“地氯雷他定”。与母体地氯雷他定相比，这些多晶型盐形式在水中以及在质子有机溶剂中显示出高得多的溶解度。制备多晶型体的方法包括：a）在约55℃至70℃的温度下混合去氯雷他定和富马酸的乙醇溶液，并在混合后搅拌30至45分钟，然后过滤固体，因此在热状态下制备; 得到DSC为232℃±2℃的多晶型2。或b）在约15℃室温（25℃）的温度下将脱氯雷他定和富马酸的乙醇溶液混合并在该温度下搅拌30至45分钟，然后在室温下过滤; 得到DSC为224℃±2℃的多晶型1

8. 发明授权

US09492003B2 Multi-purpose convertible backpack system—flipper bag 有权
标题翻译：多用途敞篷背包系统
公开(公告)号：US09492003B2
公开(公告)日：2016-11-15
申请号：US14335082
申请日：2014-07-18
申请人： Hiren Patel
发明人： Hiren Patel
IPC分类号： A45F3/04 , A44B19/38 , A47C31/10 , A45C9/00
CPC分类号： A45F3/04 , A44B19/382 , A45C9/00 , A45C2009/007 , A47C31/105 , Y10T24/25 , Y10T24/2516 , Y10T24/2534 , Y10T24/2593
摘要： A multi-purpose backpack style bag also referred as Flipper bag herein that can be used alternatively as a backpack, a handbag, or a shoulder bag. Moreover, the Flipper bag can also be converted from the backpack into a handbag without removing the contents of the handbag. The Flipper bag is made of two components, the top flipper body that is reversible, and the bottom handbag body. The bottom handbag body can be independently used as a handbag or a shoulder bag. When the top flipper body is combined with the bottom handbag body, it can be used as a backpack style bag; or the user can fold down the top flipper body over the bottom handbag body so it covers the bottom handbag body and close the flipper cover to use it as a different design of handbag.
摘要翻译：一种多功能背包风格的手提包，也称之为Flipper袋，可以替代地用作背包，手提包或肩背包。此外，还可以将手提包从背包转换成手提包而不去除手提包的内容物。 Flipper包是由两个组件组成，顶部翻盖体是可逆的，底部的手提包主体。底部手提包主体可独立用作手提包或单肩包。当顶部襟翼主体与底部手提包主体相结合时，可以用作背包风格的包; 或者用户可以将顶部襟翼主体折叠在底部手提包主体上方，使其覆盖底部手提包主体并且关闭襟翼罩以将其用作手提包的不同设计。

9. 发明授权

US08490982B2 Windback device 有权
标题翻译：回拨设备
公开(公告)号：US08490982B2
公开(公告)日：2013-07-23
申请号：US12125133
申请日：2008-05-22
申请人： Brian Roche , Glenn Garrison , Hiren Patel , John Eppehimer , Manik Vasagar , Mark Sanville , Saji Pillai
发明人： Brian Roche , Glenn Garrison , Hiren Patel , John Eppehimer , Manik Vasagar , Mark Sanville , Saji Pillai
IPC分类号： F16J15/40 , F16J15/44 , F16J15/447 , F01D11/02
CPC分类号： F01D11/02 , Y02T50/671
摘要： The present invention relates to a windback device and method of use to prevent lubricant from leaking from a lubricant sump. More specifically, the present invention is comprised of a windback device within a lubricant sump formed from the coupling of an annular sump housing, an annular fluid seal assembly, and a bearing. The annular housing substantially surrounds the runner to form a chamber. The seal assembly is coupled to a sump housing both of which are adapted to receive a rotatable runner such that a sealed chamber is formed around the runner. A plurality of inclined threads extend along an inner face of the windback device and are angled such that lubricant or fluid splashed from the rotating shaft is redirected away from a shaft seal element of the annular fluid seal and through leak off slots leading to the sump housing chamber.
摘要翻译：本发明涉及一种用于防止润滑剂从润滑剂油槽泄漏的回卷装置和方法。更具体地说，本发明包括由环形贮槽壳体，环形流体密封组件和轴承的联接器形成的润滑油槽内的回卷装置。环形壳体基本上围绕流道以形成腔室。密封组件联接到储槽壳体，两个壳体适于接收可旋转的流道，使得围绕流道形成密封室。多个倾斜螺纹沿着回卷装置的内表面延伸并且成角度使得从旋转轴飞溅的润滑剂或流体被重新导向远离环形流体密封件的轴密封元件，并且通过泄漏槽通向贮槽壳体房间。

10. 发明申请

US20100075933A1 INJECTABLE COMPOSITIONS OF VITAMIN D COMPOUNDS 审中-公开
标题翻译：维生素D化合物的注射剂组合物
公开(公告)号：US20100075933A1
公开(公告)日：2010-03-25
申请号：US12509697
申请日：2009-07-27
申请人： Sunita Vijay Shelke , Subhasish Panda , Bikash Kumar Sahoo , Ravikumar Namballa , Hiren Patel , Suryakumar Jayanthi
发明人： Sunita Vijay Shelke , Subhasish Panda , Bikash Kumar Sahoo , Ravikumar Namballa , Hiren Patel , Suryakumar Jayanthi
IPC分类号： A61K31/59
CPC分类号： A61K31/59 , A61K9/0019 , A61K47/10
摘要： Pharmaceutical injectable compositions comprising at least one vitamin D compound as an active agent, processes for preparing such compositions, and methods of using such compositions.
摘要翻译：包含至少一种维生素D化合物作为活性剂的药物可注射组合物，制备该组合物的方法和使用该组合物的方法。

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