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1. 发明授权

US06942467B2 UHV compatible lead through, device and procedure for highly effective production of nuclear spin polarized 3He at high polarization 失效
标题翻译： UHV兼容的导通，器件和程序，用于在高极化下高效生产核自旋极化3He
公开(公告)号：US06942467B2
公开(公告)日：2005-09-13
申请号：US09758006
申请日：2001-01-10
申请人： Anselm Deninger , Michael Ebert , Jan Hasse , Werner Heil , Ernst W. Otten , Jörg Schmiedeskamp , Reinhard Surkau
发明人： Anselm Deninger , Michael Ebert , Jan Hasse , Werner Heil , Ernst W. Otten , Jörg Schmiedeskamp , Reinhard Surkau
IPC分类号： A61K49/18 , F04B37/10 , F04B37/14 , F04B17/04 , F01B7/02 , F15B21/04
CPC分类号： A61K49/1815 , F04B37/10 , F04B37/14 , Y10T137/5762
摘要： There is provided an ultra high vacuum (UHV) compatible lead-through comprises (a) a housing, (b) a first space, within the housing, connected via a first port to a space outside the UHV-compatible lead through, (c) a second space, within the housing, connected via a second port to a closed system containing a polarized gas, (d) a movable component, separating the first space from the second space via an intermediate space, and (e) seals for limiting a penetration of volatile media from the first space into the second space. The lead through is particularly suited for use in the production of polarized gases, such as 3He.
摘要翻译：提供了一种超高真空（UHV）兼容的导通，其包括（a）壳体，（b）第一空间，在壳体内，经由第一端口连接到UHV兼容导线之外的空间，（c ）在所述壳体内的第二空间，经由第二端口连接到包含极化气体的封闭系统，（d）可移动部件，通过中间空间将所述第一空间与所述第二空间分离;以及（e）用于限制的密封件挥发性介质从第一空间渗入第二空间。引线通过特别适合用于生产极化气体，例如He 3 He。

2. 发明授权

US06595211B2 Magnetic resonance imaging method 失效
公开(公告)号：US06595211B2
公开(公告)日：2003-07-22
申请号：US09919879
申请日：2001-08-02
申请人： Norbert Weiler , Balthasar Eberle , Wolfgang Schreiber , Klaus Markstaller , Hans-Ulrich Kauczor , Timothy P. L. Roberts , Werner Heil , Reinhard Surkau , Anselm Deninger , Lars Lauer , Tino Grossmann , Michael Ebert
发明人： Norbert Weiler , Balthasar Eberle , Wolfgang Schreiber , Klaus Markstaller , Hans-Ulrich Kauczor , Timothy P. L. Roberts , Werner Heil , Reinhard Surkau , Anselm Deninger , Lars Lauer , Tino Grossmann , Michael Ebert
IPC分类号： A61M1600
CPC分类号： G01R33/5601
摘要： The invention provides a method of detecting regional variations in oxygen uptake from the lungs of an air-breathing animal subject, said method comprising administering into the lungs of said subject a diagnostically effective amount of a gaseous hyperpolarized magnetic resonance imaging agent, detecting the magnetic resonance signal from said agent in said lungs, determining the temporal variation in relaxation rate for said signal for at least one region of interest within said lungs, and from said variation generating a qualitative or quantitative value or image indicative of the oxygen uptake from the alveolar space in said at least one region of interest.

3. 发明授权

US06370415B1 Magnetic resonance imaging method 失效
公开(公告)号：US06370415B1
公开(公告)日：2002-04-09
申请号：US09057979
申请日：1998-04-10
申请人： Norbert Weiler , Balthasar Eberle , Wolfgang Schreiber , Klaus Markstaller , Hans-Ulrich Kauczor , Timothy P. L. Roberts , Werner Heil , Reinhard Surkau , Anselm Deninger , Lars Lauer , Tino Grossmann , Michael Ebert
发明人： Norbert Weiler , Balthasar Eberle , Wolfgang Schreiber , Klaus Markstaller , Hans-Ulrich Kauczor , Timothy P. L. Roberts , Werner Heil , Reinhard Surkau , Anselm Deninger , Lars Lauer , Tino Grossmann , Michael Ebert
IPC分类号： A61B5055
CPC分类号： G01R33/5601
摘要： The invention provides a method of detecting regional variations in oxygen uptake from the lungs of an air-breathing animal subject, said method comprising administering into the lungs of said subject a diagnostically effective amount of a gaseous hyperpolarized magnetic resonance imaging agent, detecting the magnetic resonance signal from said agent in said lungs, determining the temporal variation in relaxation rate for said signal for at least one region of interest within said lungs, and from said variation generating a qualitative or quantitative value or image indicative of the oxygen uptake from the alveolar space in said at least one region of interest.

4. 发明授权

US07176386B1 Magnetically shielded container 失效
标题翻译：磁屏蔽容器
公开(公告)号：US07176386B1
公开(公告)日：2007-02-13
申请号：US09509317
申请日：1998-09-24
申请人： Elke Aidam , Michael Ebert , Tino Grossmann , Werner Heil , Ernst-Wilhelm Otten , Daniela Rohe , Reinhard Surkau
发明人： Elke Aidam , Michael Ebert , Tino Grossmann , Werner Heil , Ernst-Wilhelm Otten , Daniela Rohe , Reinhard Surkau
IPC分类号： H05K9/00 , G21F5/06 , G01V3/14
CPC分类号： G21F5/00 , G21Y2002/301 , G21Y2002/305 , G21Y2004/30
摘要： The invention provides a magnetically shielded container (1) having disposed in parallel opposed position on an axis (S) thereof magnetic field homogenizing pole shoes (10.1, 10.2), having disposed about said pole shoes a magnetically shielded yoke (2), said pole shoes and yoke enclosing a magnetic chamber (26), said container further comprising magnetic field sources (2.4, 2.5) disposed about and radially distanced from said axis whereby there exists within said chamber substantially homogenous magnetic field Bo oriented in the direction of said axis and whereby there is a usable volume within said chamber where the ratio of the magnetic field gradient in the direction transverse to said axis to said magnetic field Bo has a value of no more than 1.5×10−3/cm. By virtue of the very low ratio of weight to volume that is achievable with this construction, the containers according to the invention are economical to produce and especially suited to transporting polarized gasses.
摘要翻译：本发明提供了一种磁屏蔽容器（1），其在其磁极均质极靴（10.1,10.2）的轴线（S）上平行地相对位置设置，其具有围绕所述极靴设置的磁屏蔽轭（2），所述极包围磁性室（26）的鞋和轭，所述容器还包括设置在所述轴线周围和径向远离所述轴线的磁场源（2.4,2.5），由此在所述腔室内基本上均匀的磁场B < 在所述轴的方向上定向，并且由此在所述腔室内存在可用的体积，其中横向于所述轴线的方向上的磁场梯度与所述磁场B < 大于1.5×10 -3 / cm。由于通过这种结构实现的重量与体积的非常低的比例，根据本发明的容器是经济的，特别适用于输送极化气体。

5. 发明申请

US20070145305A1 Magnetically shielded container 审中-公开
标题翻译：磁屏蔽容器
公开(公告)号：US20070145305A1
公开(公告)日：2007-06-28
申请号：US11652250
申请日：2007-01-11
申请人： Elke Aidam , Michael Ebert , Tino Grossmann , Werner Heil , Ernst-Wilhelm Otten , Daniela Rohe , Reinhard Surkau
发明人： Elke Aidam , Michael Ebert , Tino Grossmann , Werner Heil , Ernst-Wilhelm Otten , Daniela Rohe , Reinhard Surkau
IPC分类号： G21F3/00 , G21F1/00 , B65D85/00
CPC分类号： G21F5/00
摘要： A gas storage cell containing a nuclear spin polarized gas in a gas storage space surrounded by a cell wall made of an uncoated material having a surface substantially free of paramagnetic substances which is in contact with the gas storage space and a method for removing the nuclear spin polarized gas from the gas storage cell.
摘要翻译：在由具有基本上不含与气体存储空间接触的顺磁性物质的表面的未涂覆材料制成的电池壁包围的气体储存空间中的含有自旋极化气体的气体储存电池以及用于除去核旋转的方法来自气体存储单元的极化气体。

6. 发明授权

US06486666B1 Method and apparatus for measuring the degree of polarization of polarized gas 失效
标题翻译：用于测量极化气体极化度的方法和装置
公开(公告)号：US06486666B1
公开(公告)日：2002-11-26
申请号：US09509229
申请日：2000-05-18
申请人： Tino Grossmann , Werner Heil , Daniela Rohe , Reinhard Surkau , Elke Aidam , Michael Ebert , Ernst-Wilhelm Otten
发明人： Tino Grossmann , Werner Heil , Daniela Rohe , Reinhard Surkau , Elke Aidam , Michael Ebert , Ernst-Wilhelm Otten
IPC分类号： G01V300
CPC分类号： G01N24/00
摘要： The invention relates to a method for determining the degree of polarization (P) of a nuclear spin polarized gas, in particular 3He, 129Xe, in which the nuclear spin polarized gas is placed in a container, comprising determining the magnetic field Bd of the pola gas by measuring the magnetic dipole field emerging therefrom and then determining from Bd the degree of polarization of the gas.
摘要翻译：本发明涉及一种用于确定核自旋极化气体，特别是3He，129Xe的偏振度（P）的方法，其中核自旋极化气体放置在容器中，包括确定极性的磁场Bd 通过测量从其出现的磁偶极场，然后从Bd确定气体的极化度。

7. 发明授权

US08295943B2 Implantable medical lead with biased electrode 有权
标题翻译：带有偏置电极的植入式医用导线
公开(公告)号：US08295943B2
公开(公告)日：2012-10-23
申请号：US12195287
申请日：2008-08-20
申请人： Michael D. Eggen , John L. Sommer , Michael Ebert , David Wayne Bourn , Gabriela C. Miyazawa
发明人： Michael D. Eggen , John L. Sommer , Michael Ebert , David Wayne Bourn , Gabriela C. Miyazawa
IPC分类号： A61N1/05
CPC分类号： A61N1/056 , A61N1/05 , A61N1/0534 , A61N1/0551 , A61N2001/0585
摘要： This disclosure describes implantable medical leads that include a lead body and an electrode. A width of the electrode as measured along a longitudinal direction of the lead varies about the perimeter of the lead. The uneven width of the electrode may bias a stimulation field in a particular direction, e.g., a radial or transverse direction relative to the longitudinal axis of the lead. Electrodes with an uneven width may be useful for controlling the direction of propagation of the stimulation field in order to, for example, avoid phrenic nerve stimulation during LV pacing or neck muscle stimulation during vagal neurostimulation.
摘要翻译：本公开描述了包括引线体和电极的可植入医疗引线。沿着铅的纵向测量的电极的宽度围绕导线的周边变化。电极的不均匀宽度可以相对于引线的纵向轴线在特定方向（例如，径向或横向）偏置刺激场。具有不均匀宽度的电极可用于控制刺激场的传播方向，以便例如在迷走神经刺激期间在LV起搏或颈部肌肉刺激期间避免膈神经刺激。

8. 发明申请

US20120144140A1 Memory Protection Unit and a Method for Controlling an Access to a Memory Device 有权
标题翻译：存储器保护单元和用于控制对存储器件的访问的方法
公开(公告)号：US20120144140A1
公开(公告)日：2012-06-07
申请号：US13306715
申请日：2011-11-29
申请人： Christine Rossa , Bernd Mueller , Markus Ferch , Carsten Gebauer , Dieter Thoss , Michael Ebert
发明人： Christine Rossa , Bernd Mueller , Markus Ferch , Carsten Gebauer , Dieter Thoss , Michael Ebert
IPC分类号： G06F12/14
CPC分类号： G06F12/1425 , G06F21/79
摘要： A memory protection unit includes at least a first access control unit and a second access control unit programmed for controlling an access to a memory device. Further a method to operate a processing system comprising multiple processing devices and multiple memory protection units associated to the multiple processing devices, The access to the memory by a processing device is approved if first access control unit and second access control unit of the memory protection associated to the processing device approves the access and access is rejected if first access control unit or second access control unit rejects the access. The first access control unit is programmable by the associated processing device alone and the programming of the second access control unit is readable by an additional processing device which is to be used in a system with multiple programming devices, not the associate processing device.
摘要翻译：存储器保护单元至少包括第一访问控制单元和被编程用于控制对存储器设备的访问的第二访问控制单元。此外，操作包括与多个处理设备相关联的多个处理设备和多个存储器保护单元的处理系统的方法。如果存储器保护的第一访问控制单元和第二访问控制单元相关联，则由处理设备访问存储器被批准如果第一访问控制单元或第二访问控制单元拒绝该访问，则处理设备批准该访问和访问被拒绝。第一访问控制单元可以由相关联的处理设备单独编程，并且第二访问控制单元的编程可由附加处理设备读取，该附加处理设备将用于具有多个编程设备的系统中，而不是关联处理设备。

9. 发明申请

US20090309314A1 Bushing 有权
标题翻译：衬套
公开(公告)号：US20090309314A1
公开(公告)日：2009-12-17
申请号：US12456183
申请日：2009-06-12
申请人： Andreas Erl , Michael Ebert , Majid Djahani
发明人： Andreas Erl , Michael Ebert , Majid Djahani
IPC分类号： F16J15/12
CPC分类号： F16F13/1454
摘要： A bushing, including a core, a sleeve that surrounds the core and a spring element that is arranged between the core and the sleeve, wherein, on at least one face of the bushing, there is a sealing element that seals the spring element vis-à-vis the environment.
摘要翻译：一种衬套，包括芯部，围绕芯部的套筒和布置在芯部和套筒之间的弹簧元件，其中在衬套的至少一个表面上存在密封元件，对环境。

10. 发明申请

US20090054941A1 STIMULATION FIELD MANAGEMENT 审中-公开
标题翻译：刺激现场管理
公开(公告)号：US20090054941A1
公开(公告)日：2009-02-26
申请号：US12195313
申请日：2008-08-20
申请人： Michael D. Eggen , John L. Sommer , Michael Ebert , David Wayne Bourn , Gabriela C. Miyazawa
发明人： Michael D. Eggen , John L. Sommer , Michael Ebert , David Wayne Bourn , Gabriela C. Miyazawa
IPC分类号： A61N1/05 , A61N1/362
CPC分类号： A61N1/0565 , A61N2001/0585
摘要： This disclosure describes techniques for controlling a depth of propagation of a stimulation field extending from an outer diameter of a lead body of an implantable stimulation lead. An implantable electrical stimulation lead may include a lead body, and at least one electrode arranged as a ring. An outer diameter of the ring may be different than an outer diameter of the lead body. A ring with a diameter smaller than the diameter of the lead body may be useful in limiting the depth of propagation of the stimulation field within patient tissue. A ring with a diameter greater than the diameter of the lead body may be useful in extending the depth of propagation of the stimulation field.
摘要翻译：本公开描述了用于控制从可植入刺激引线的引线体的外径延伸的刺激场的传播深度的技术。可植入电刺激引线可以包括引线体，以及布置成环的至少一个电极。环的外径可以与引线体的外径不同。直径小于引线主体直径的环可用于限制刺激场在患者组织内的传播深度。具有大于引线主体直径的直径的环可以用于延长刺激场的传播深度。

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