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1. 发明专利

JP2004358234A Needleless syringe with a plurality of nozzle holes 审中-公开
公开(公告)号：JP2004358234A
公开(公告)日：2004-12-24
申请号：JP2004139364
申请日：2004-05-10
申请人： Anges Mg Inc , Ryuichi Morishita , Shimadzu Corp , アンジェスMg株式会社 , 株式会社島津製作所 , 竜一森下
发明人： MORISHITA RYUICHI , TOMITA NARUYA , KUNUGIZA YASUO , TANIYAMA YOSHIAKI , KOIKE HIROMI , UDAGAWA HARUHIDE , KIMURA TATSUO
IPC分类号： C12N15/09 , A61K31/7088 , A61K35/74 , A61K38/00 , A61K38/22 , A61K38/27 , A61K38/43 , A61K38/55 , A61K48/00 , A61M5/30 , A61P9/00 , A61P9/10 , A61P19/02 , A61P19/08 , A61P29/00 , A61P35/04 , A61P37/06 , A61P37/08
CPC分类号： A61M5/30 , A61M5/19
摘要： PROBLEM TO BE SOLVED: To provide a needleless syringe for jet-injecting various kinds of medical solutions from a plurality of nozzle holes to uniformly inject them into the whole treated part. SOLUTION: The needleless syringe comprises a medical solution chamber 22 for storing the medical solution L, formed with the plurality of nozzle holes 94 and provided with a plurality of pistons 93 corresponding to the plurality of nozzle holes 94 respectively, and a syringe body 12 provided with a pressing mechanism 32 for pressing the pistons 93 toward the nozzle holes 94 to inject the medical solution L from the nozzle holes 94. COPYRIGHT: (C)2005,JPO&NCIPI

2. 发明专利

CA2525017A1 NEEDLELESS SYRINGE HAVING MEDICAL AGENT ACCOMMODATED THEREIN 未知
公开(公告)号：CA2525017A1
公开(公告)日：2004-12-23
申请号：CA2525017
申请日：2004-04-30
申请人： ANGES MG INC , SHIMADZU CORP , MORISHITA RYUICHI
发明人： KOIKE HIROMI , TANIYAMA YOSHIAKI , KUNUGIZA YASUO , TOMITA NARUYA , UDAGAWA HARUHIDE , KIMURA TATSUO , MORISHITA RYUICHI
IPC分类号： A61M5/30 , A61K38/18 , A61K48/00 , C12N15/00
摘要： A needleless syringe having, accommodated therein, a pharmaceutical preparation containing genes and/or analogues thereof. In particular, a needleless syringe having syringe main body (12) including medical agent chamber (22), the medical agent chamber (22) fitted with one or multiple nozzle bores (25) and having medical agent (L) accommodated therein, and pressure application means (32), the pressure application means (32) capable of applying pressure on the medical agent (L) toward the nozzle bores (25) t o thereby effect emission of the medical agent (L) through the nozzle bores (25), wherein the medical agent (L) is a pharmaceutical preparation containi ng genes and/or analogues thereof. As the medical agent (L), there can be mentioned, for example, a pharmaceutical preparation containing HGF gene and a pharmaceutical preparation containing NF-.kappa.B decoyoligonucleotide.

3. 发明专利

AU2004246913A1 Needleless syringe having medical agent accommodated therein 未知
公开(公告)号：AU2004246913A1
公开(公告)日：2004-12-23
申请号：AU2004246913
申请日：2004-04-30
申请人： ANGES MG INC , MORISHITA RYUICHI , SHIMADZU CORP
发明人： TOMITA NARUYA , TANIYAMA YOSHIAKI , MORISHITA RYUICHI , KOIKE HIROMI , KUNUGIZA YASUO , UDAGAWA HARUHIDE , KIMURA TATSUO
IPC分类号： A61M5/30 , A61K38/18 , A61K48/00 , C12N15/00
摘要： The present invention provides a needleless syringe having, accommodated therein, a pharmaceutical preparation containing genes and/or analogues thereof. A needleless syringe comprising: a medical agent chamber 22 having one or multiple nozzle bore(s) 25 and accommodated with a medical agent L, and a syringe main body 12 being provided with pressure application means 32 to apply pressure on the medical agent L toward a direction of the nozzle bore (s) 25 and effect emission of the medical agent L through the nozzle bore (s) 25, wherein the medical agent L is a pharmaceutical preparation containing genes and/or analogues thereof. Examples of the medical agent L include pharmaceutical preparation containing HGF gene and pharmaceutical preparation containing NF-ºB decoy oligonucleotide.

4. 发明专利

JP2015033561A 脳機能計測装置および脳機能計測装置用計測プローブ审中-公开
标题翻译：脑功能测量装置和脑功能测量装置的测量探头
公开(公告)号：JP2015033561A
公开(公告)日：2015-02-19
申请号：JP2013167103
申请日：2013-08-09
申请人：株式会社島津製作所 , Shimadzu Corp
发明人： UDAGAWA HARUHIDE , INOUE YOSHIHIRO , ISHIKAWA AKIHIRO , MASUDA YOSHIAKI , AMITA KOUJI , YAMAGUCHI SHUNPEI , UNO HARUO
IPC分类号： A61B10/00 , A61B5/1455
摘要：【課題】有毛部において計測プローブを頭部表面に容易に接触させながら、無毛部において計測プローブを頭部表面に接触させる際の痛みを被験者に感じにくくすることが可能な脳機能計測装置を提供する。【解決手段】光計測装置(脳機能計測装置)は、被験者の頭部101に配置される複数の計測プローブと、複数の計測プローブの各々と接続され、計測プローブを介して計測を行う本体部とを備える。複数の計測プローブは、被験者の頭部側の先端部20aにおいて、第1接触部を有する第1プローブと、被験者の頭部表面側の面積が第1接触部よりも大きい第2接触部40を有する第2プローブとを含む。【選択図】図4
摘要翻译：要解决的问题：提供一种脑功能测量装置，当测量探针与无毛区域的头部表面接触时，能够防止受试者几乎不感到疼痛，同时容易地使测量探针与头部接触毛发区域的部分表面。解决方案：光学测量装置（脑功能测量装置）包括要设置在对象的头部101上的多个测量探针和连接到多个测量探针中的每一个的主体部分并通过测量探头进行测量。多个测量探针包括在被检体的头侧的前端部20a具有第一接触部的第一探针和具有第二接触部40的第二探针，第二接触部40的头表面侧的区域受试者大于第一接触部分的受试者。

5. 发明专利

JP2008206477A Method for cell inoculation using needleless syringe 审中-公开
标题翻译：使用无针刺激进行细胞培养的方法
公开(公告)号：JP2008206477A
公开(公告)日：2008-09-11
申请号：JP2007047829
申请日：2007-02-27
申请人： National Cardiovascular Center , Shimadzu Corp , 国立循環器病センター総長 , 株式会社島津製作所
发明人： FUJISATO TOSHIYA , SOMEKAWA SHOTA , EHASHI TOMO , TOGAWA YUICHI , NAKATANI TAKESHI , UDAGAWA HARUHIDE
IPC分类号： A61L27/00 , A61M5/30 , C12M3/00 , C12N5/07 , C12N5/071
CPC分类号： C12M33/04
摘要： PROBLEM TO BE SOLVED: To provide a very simple method for inoculating cells, enabling the cells to be embedded in the inside of a scaffold without causing significant damage of the scaffold itself, and also enabling the cells to be dispersed widely in the scaffold even if the scaffold has a dense structure.
SOLUTION: The method comprises injecting to-be-inoculated cells into a scaffold using a needleless syringe to embed the cells in the inside of the scaffold.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：为了提供接种细胞的非常简单的方法，使细胞嵌入在支架内部，而不会引起支架本身的显着损伤，并且还使细胞能够广泛分散在支架即使支架具有致密结构。解决方案：该方法包括使用无针注射器将待接种细胞注入支架，将细胞嵌入支架内部。版权所有（C）2008，JPO＆INPIT

6. 发明专利

JP2008086689A Needleless injector 有权
标题翻译：无针注射器
公开(公告)号：JP2008086689A
公开(公告)日：2008-04-17
申请号：JP2006273790
申请日：2006-10-05
申请人： Shimadzu Corp , 株式会社島津製作所
发明人： UDAGAWA HARUHIDE
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2053
摘要： PROBLEM TO BE SOLVED: To provide a needleless injector of simple constitution, with a wide adjustable range of medicine injection force, and a low impact noise. SOLUTION: In a back side grip 5, a partition wall 5c having a gas communication hole 5b is formed, and a chamber lid 6 is thread-attached. An inner space of it is used as a gas chamber part 7 for storing high pressure gas, and a forward inner space of the partition wall 5c is used as a cylinder 5d. A pressure receiving piston 9 is disposed in the cylinder 5d to be connected to a piston 10 to slide and move on an inner circumferential surface. To the chamber lid 6, an injection button 15 to be connected to a communication hole opening/closing rod 16 to open/close the gas communication hole 5b, and a joint 13 with a residual pressure exhaust valve having a push button 14 to exhaust the high pressure gas in the gas chamber part 7 are fixed. A nozzle 2 of a front side grip 4 is applied to a medicine vial, and the back side grip 5 is retracted to suck medicine. The injection button 15 is pushed to move the high pressure gas preliminarily stored in the gas chamber part 7 into the cylinder 5d. The pressure receiving piston 9 is thus pressurized to advance to jet-spray the medicine. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种简单结构的无针注射器，具有广泛的药物注射力可调范围和低冲击噪音。解决方案：在后侧手柄5中，形成具有气体连通孔5b的分隔壁5c，并且安装腔室盖6。其内部空间用作用于储存高压气体的气室部分7，分隔壁5c的前内部空间用作气缸5d。压力接收活塞9设置在气缸5d中以连接到活塞10，以在内周面上滑动和移动。连接到连通孔打开/关闭杆16以打开/关闭气体连通孔5b的喷射按钮15和具有按钮14的残余排气阀的接头13排出到室盖6，气室部7中的高压气体被固定。前侧把手4的喷嘴2被施加到药瓶，并且后侧把手5缩回以吸取药物。按压喷射按钮15，将预先存储在气室部7中的高压气体移动到气缸5d内。压力接收活塞9被加压以推进喷射药物。版权所有（C）2008，JPO＆INPIT

7. 发明专利

JP2007289409A Needle less syringe 有权
标题翻译：针刺不足
公开(公告)号：JP2007289409A
公开(公告)日：2007-11-08
申请号：JP2006120828
申请日：2006-04-25
申请人： Shimadzu Corp , 株式会社島津製作所
发明人： UDAGAWA HARUHIDE
IPC分类号： A61M5/30
CPC分类号： A61M5/30
摘要： PROBLEM TO BE SOLVED: To provide a needle less syringe with small impact noise in injecting a medical solution. SOLUTION: A latch mechanism of the syringe is composed of a latch ball receiver 9 with a plurality of pores 9a fixed to a rear-side cylinder part 12 to fit in a latch ball 8; a groove part 7a formed in a piston rod 7; a latch releasing button 11 to which a ball presser 16 to form a presser face 16a and a cylindrical cushion member 15 to form a butting face 15a; and a compression spring 17 interposed between the latch ball receiver 9 and the ball presser 16 to energize the latch releasing button 11 backward. With this structure, the impact noise generated when the latch ball 8 collides with the butting face 15a of the cushion member 15 in releasing the latch is reduced. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供注射医疗溶液时具有小冲击噪音的针头注射器。解决方案：注射器的闩锁机构由具有多个孔9a的闩锁球接收器9组成，多个孔9a固定到后侧圆柱体部分12以装配在闩锁球8中; 形成在活塞杆7中的槽部7a; 闩锁释放按钮11，用于形成压脚面16a的滚珠压脚16和形成对接面15a的圆筒形缓冲构件15; 以及插入在闩锁球接收器9和球按压器16之间的压缩弹簧17，以向后推动闩锁释放按钮11。通过这种结构，在释放闩锁时，当闩锁球8与缓冲构件15的对接面15a碰撞时产生的冲击噪声减小。版权所有（C）2008，JPO＆INPIT

8. 发明专利

JP2010085484A Imaging lens and imaging apparatus 有权
标题翻译：成像镜头和成像设备
公开(公告)号：JP2010085484A
公开(公告)日：2010-04-15
申请号：JP2008251802
申请日：2008-09-29
申请人： Kyocera Optec Co Ltd , Shimadzu Corp , 京セラオプテック株式会社 , 株式会社島津製作所
发明人： FURUTA HIROYUKI , UDAGAWA HARUHIDE
IPC分类号： G02B13/00 , G02B13/18
摘要： PROBLEM TO BE SOLVED: To provide a large-diameter low-distortion wide-angle imaging lens the overall length of which is short, and an imaging apparatus.
SOLUTION: The present technology includes a first lens L1 having a negative power, a second lens L2 having a negative power, a third lens L3 having a positive power, a fourth lens L4 having a positive power, a fifth lens L5 having a negative power, a sixth lens L6 having a positive power, and a seventh lens L7 having a positive power arranged in this order from an object OBJ side. At least two of the first lens L1, the second lens L2, the third lens L3, the fourth lens L4, the fifth lens L5, the sixth lens L6 and the seventh lens L7 are nonspherical lenses, and the first lens L1 and the sixth lens L6 are nonspherical lenses.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供其整体长度短的大直径低失真广角成像透镜和成像装置。解决方案：本技术包括具有负功率的第一透镜L1，具有负功率的第二透镜L2，具有正光焦度的第三透镜L3，具有正光焦度的第四透镜L4，具有正光焦度的第五透镜L4，负电源，具有正电力的第六透镜L6和具有正功率的第七透镜L7从物体OBJ侧依次排列。第一透镜L1，第二透镜L2，第三透镜L3，第四透镜L4，第五透镜L5，第六透镜L6和第七透镜L7中的至少两个是非球面透镜，并且第一透镜L1和第六透镜透镜L6是非球面透镜。版权所有（C）2010，JPO＆INPIT

9. 发明专利

JP2010069061A X-ray sensor and x-ray apparatus using the same 审中-公开
标题翻译： X射线传感器和X射线设备使用它
公开(公告)号：JP2010069061A
公开(公告)日：2010-04-02
申请号：JP2008240654
申请日：2008-09-19
申请人： Shimadzu Corp , 株式会社島津製作所
发明人： UDAGAWA HARUHIDE
IPC分类号： A61B6/00 , G01T1/00 , G01T1/20
摘要： PROBLEM TO BE SOLVED: To provide an X-ray sensor capable of easily and accurately executing the correction work to create correction information for correcting two-dimensional distortion and displacement in the image of a subject; and X-ray apparatus using the same. SOLUTION: The X-ray sensor 10 includes: a flat fluorescent panel 32 for converting radiation information to fluorescent information by applying the radiation information obtained by transmission of the radiation through the subject to an irradiation surface 32a, and emitting the fluorescence based on the fluorescent information from an emission surface 32b; a sensor module 94a having a plurality of two-dimensionally arrayed photoelectric conversion elements 80a; and a lens unit 93a for guiding the fluorescence emitted from the emission surface 32b of the fluorescent panel 32 to the plurality of photoelectric conversion elements 80a. The X-ray sensor creates the image of the subject by two-dimensionally arranging electric signals from the plurality of photoelectric conversion elements 80a. A plurality of markers 30a to absorb the fluorescence at a preset rate are positioned and printed in such a way as to be two-dimensionally and regularly arrayed on the emission surface 32b of the fluorescent panel 32. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供能够容易且准确地执行校正工作的X射线传感器，以创建用于校正被摄体的图像中的二维畸变和位移的校正信息; 和使用其的X射线装置。解决方案：X射线传感器10包括：平面荧光板32，用于通过将通过对象的辐射透射获得的辐射信息应用于照射表面32a，将辐射信息转换为荧光信息，并发射基于荧光的荧光对来自发射表面32b的荧光信息; 具有多个二维排列的光电转换元件80a的传感器模块94a; 以及用于将从荧光板32的发射面32b发出的荧光引导到多个光电转换元件80a的透镜单元93a。 X射线传感器通过二维布置来自多个光电转换元件80a的电信号来创建被摄体的图像。以预定速率吸收荧光的多个标记物30a被定位并印刷成二维和规则地排列在荧光板32的发射表面32b上。版权所有（C）2010 ，JPO＆INPIT

10. 发明专利

JP2009247762A Needleless injector 审中-公开
标题翻译：无针注射器
公开(公告)号：JP2009247762A
公开(公告)日：2009-10-29
申请号：JP2008102068
申请日：2008-04-10
申请人： Shimadzu Corp , 株式会社島津製作所
发明人： UDAGAWA HARUHIDE
IPC分类号： A61M5/30
摘要： PROBLEM TO BE SOLVED: To provide a needleless injector which can use gas pressure to suck/jet a drug liquid and is high in quantitativeness of the amount of the drug liquid to be injected. SOLUTION: The needleless injector includes a cylinder body 4 in which a partition wall 4c is formed to have a communication hole 4b; a gas chamber 4e which is formed by screwing a cap 41 to the back end and is mounted with a pressure piston 52 sliding on the inner circumferential surface; a gas chamber 4d which is in front of the partition wall 4c and is equipped with a ball stopper 65 sliding on the inner circumferential surface; a gas supply/exhaust selector 7 for supplying/exhausting gas for the gas chamber 4d; and a gas supply/exhaust selector 8 for supplying/exhausting gas for the gas chambers 41a and 4e. A nozzle holder 3 is moved forward to suck a drug liquid Y from a drug vial B, and then a lever 71 is drawn to supply the gas chamber 4d with a high pressure gas G, and then the ball stopper 65 is moved forward and a latch is taken off, and then the pressure piston 52 is moved forward to jet the drug liquid Y. In order to suck a fresh drug liquid Y from the drug vial B again, the gas chamber 4e is supplied with the high pressure gas G, and the gas chamber 41a is exhausted of the high pressure gas G, and then the pressure piston 52 is moved backward. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种能够使用气体压力来吸引/喷射药物液体的无针注射器，并且高剂量的待注射药物液体的量。解决方案：无针注射器包括：缸体4，分隔壁4c形成在其中，具有连通孔4b; 气体室4e，其通过将盖41拧到后端而形成，并且安装有在内周面上滑动的压力活塞52; 位于分隔壁4c前方的气室4d，并配有在内周面滑动的球止动件65; 用于为气室4d供给/排出气体的气体供给/排气选择器7; 以及用于为气室41a和4e供给/排出气体的气体供给/排气选择器8。向前方移动喷嘴保持架3，从药瓶B吸取药液Y，然后拉动杆71，向气体室4d供给高压气体G，然后使球塞65向前方移动，取下闩锁，然后压力活塞52向前移动以喷射药液Y.为了再次从药瓶B吸入新鲜药液Y，气室4e被供给高压气体G，并且气室41a排出高压气体G，然后压力活塞52向后移动。版权所有（C）2010，JPO＆INPIT

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