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1. 发明申请

US20060189639A1 Antagonists of the mGlu receptor and uses thereof 审中-公开
标题翻译： mGlu受体的拮抗剂及其用途
公开(公告)号：US20060189639A1
公开(公告)日：2006-08-24
申请号：US11333035
申请日：2006-01-17
申请人： Andrew Stewart , Guo Zheng , Teodozyj Kolasa , Pramila Bhatia , Jerome Daanen , Steven Latshaw , Xueqing Wang
发明人： Andrew Stewart , Guo Zheng , Teodozyj Kolasa , Pramila Bhatia , Jerome Daanen , Steven Latshaw , Xueqing Wang
IPC分类号： A61K31/519 , C07D498/14
CPC分类号： C07D493/14 , C07D495/14
摘要： The present invention discloses compounds of general formula (I) wherein X1-X4 and R1-R3 are as defined in the description. The present invention also discloses methods of treatment for pain, neurodegeneration and convulsive states in a host mammal in need thereof, and pharmaceutical compositions including those compounds.
摘要翻译：本发明公开了通式（I）的化合物，其中X 1 -X 4 -X 3和R 1 -R 3 >如说明书中所定义。本发明还公开了在有需要的宿主哺乳动物中治疗疼痛，神经变性和惊厥状态的方法，以及包括那些化合物的药物组合物。

2. 发明申请

US20060009461A1 Acetamides and benzamides that are useful in treating sexual dysfunction 审中-公开
公开(公告)号：US20060009461A1
公开(公告)日：2006-01-12
申请号：US11223857
申请日：2005-09-09
申请人： Pramila Bhatia , Jerome Daanen , Ahmed Hakeem , Teodozyj Kolasa , Mark Matulenko , Kathleen Mortell , Meena Patel , Andrew Stewart , Xueqing Wang , Zhiren Xia , Henry Zhang
发明人： Pramila Bhatia , Jerome Daanen , Ahmed Hakeem , Teodozyj Kolasa , Mark Matulenko , Kathleen Mortell , Meena Patel , Andrew Stewart , Xueqing Wang , Zhiren Xia , Henry Zhang
IPC分类号： A61K31/506 , A61K31/501 , A61K31/496
CPC分类号： A61K31/00 , A61K31/40 , A61K31/4025 , A61K31/41 , A61K31/427 , A61K31/4418 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/445 , A61K31/4523 , A61K31/4535 , A61K31/454 , A61K31/4545 , A61K31/495 , A61K31/496 , A61K31/501 , A61K31/506
摘要： The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.

3. 发明申请

US20050176727A1 Oximes and hydrazones that are useful in treating sexual dysfunction 审中-公开
标题翻译：用于治疗性功能障碍的肟和腙
公开(公告)号：US20050176727A1
公开(公告)日：2005-08-11
申请号：US10773035
申请日：2004-02-05
申请人： Teodzyj Kolasa , Meena Patel , Kathleen Mortell , Mark Matulenko , Ahmed Hakeem , Pramila Bhatia , Xueqing Wang , Jerome Daanen , Steven Latshaw , Andrew Stewart
发明人： Teodzyj Kolasa , Meena Patel , Kathleen Mortell , Mark Matulenko , Ahmed Hakeem , Pramila Bhatia , Xueqing Wang , Jerome Daanen , Steven Latshaw , Andrew Stewart
IPC分类号： A61K31/496 , C07D207/08 , C07D211/14 , C07D213/74 , C07D213/85 , C07D239/42 , C07D277/38 , C07D295/13 , C07D401/04 , C07D403/04 , C07D417/04 , C07D43/04
CPC分类号： C07D207/08 , C07D211/14 , C07D213/74 , C07D213/85 , C07D239/42 , C07D277/38 , C07D295/13 , C07D401/04 , C07D403/04 , C07D417/04
摘要： The present invention relates to oximes and hydrazones of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
摘要翻译：本发明涉及用于治疗性功能障碍的式（I）的肟和腙以及含有用于治疗性功能障碍的式（I）化合物的组合物。

4. 发明申请

US20070265249A1 Fused Bicyclic Aromatic Compounds that are Useful in Treating Sexual Dysfunction 有权
标题翻译：用于治疗性功能障碍的融合双环芳香化合物
公开(公告)号：US20070265249A1
公开(公告)日：2007-11-15
申请号：US11747955
申请日：2007-05-14
申请人： Marlon Cowart , Steven Latshaw , Sherry Nelson , Andrew Stewart
发明人： Marlon Cowart , Steven Latshaw , Sherry Nelson , Andrew Stewart
IPC分类号： A61K31/44 , A61K31/445 , A61K31/497 , A61K31/55 , A61P15/00
CPC分类号： A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/495 , A61K31/496 , C07D471/04 , C07D491/04 , C07D495/04 , C07D513/04
摘要： The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B1 are as described in the specification.
摘要翻译：本发明涉及式（I）化合物用于治疗性功能障碍的用途和含有式（I）化合物用于治疗性功能障碍的组合物的用途，其中A，L，D和B < / SUB>如说明书中所述。

5. 发明申请

US20060172995A1 Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction 有权
标题翻译：用于治疗性功能障碍的稠合双环芳香化合物
公开(公告)号：US20060172995A1
公开(公告)日：2006-08-03
申请号：US11395807
申请日：2006-03-31
申请人： Marlon Cowart , Steven Latshaw , Sherry Nelson , Andrew Stewart
发明人： Marlon Cowart , Steven Latshaw , Sherry Nelson , Andrew Stewart
IPC分类号： A61K31/551 , A61K31/519
CPC分类号： A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/495 , A61K31/496 , C07D471/04 , C07D491/04 , C07D495/04 , C07D513/04
摘要： The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction, wherein A, L, D and B, are as described in the specification.
摘要翻译：本发明涉及式（I）化合物用于治疗性功能障碍的用途，以及含有式（I）化合物用于治疗性功能障碍的组合物的用途，其中A，L，D和B如规格。

6. 发明授权

US06855358B1 Process for addition of a nutraceutical to a beverage 失效
标题翻译：向饮料添加营养药物的方法
公开(公告)号：US06855358B1
公开(公告)日：2005-02-15
申请号：US10286345
申请日：2002-11-01
申请人： Steve Nickolas , Andrew Stewart
发明人： Steve Nickolas , Andrew Stewart
IPC分类号： A23L1/30 , A23L2/44 , A23L2/46 , A23L3/16 , A23L3/358 , A23B4/24
CPC分类号： A23L3/16 , A23L2/44 , A23L2/46 , A23L3/358 , A23L33/105 , A23V2002/00 , A23V2200/10 , A23V2250/128 , A23V2250/1588 , A23V2250/2118 , A23V2250/28 , A23V2250/21
摘要： The present invention discloses a method of introducing a nutraceutical to a beverage comprising treating a beverage with a primary sterilizing agent, such as ozonation, filling a container with said beverage, adding an amount of a nutraceutical and sealing said container. The present invention allows for the production of a suitably sterile beverage without a substantial loss in the activity, or change in the structure, of a nutraceutical.
摘要翻译：本发明公开了一种向饮料中引入营养保健品的方法，包括用主要灭菌剂如臭氧化处理饮料，用所述饮料填充容器，加入一定数量的营养食品并密封所述容器。本发明允许生产适当无菌饮料，而不会显着损失营养品的活性或结构变化。

7. 发明申请

US20120301064A1 HANGER BEARING COUPLING 有权
标题翻译：挂钩联轴器
公开(公告)号：US20120301064A1
公开(公告)日：2012-11-29
申请号：US13479367
申请日：2012-05-24
申请人： Andrew Stewart
发明人： Andrew Stewart
IPC分类号： F16C35/02
CPC分类号： F16C35/02 , F16C33/76
摘要： The present device is a hanger bearing coupling which includes a bearing for supporting a shaft, the bearing including an inner race mounted onto the shaft, the bearing mounted between at least two hub assemblies mounted one on either side of the bearing on the shaft; and a hanger including an opening for receiving the bearing there through for operably connecting the bearing to the hanger. Each hub assembly including an inner flex hub mounted to the shaft and an outer flex hub resiliently mounted to the inner flex hub wherein the outer flex hubs are adapted to connect to tubular shafts which may be longitudinally misaligned.
摘要翻译：本装置是一种衣架轴承联轴器，其包括用于支撑轴的轴承，所述轴承包括安装在所述轴上的内座圈，所述轴承安装在安装在所述轴上的所述轴承的任一侧上的至少两个轮毂组件之间; 以及衣架，其包括用于接收其中的轴承的开口，用于将轴承可操作地连接到衣架。每个轮毂组件包括安装到轴的内部柔性轮毂和弹性地安装到内部柔性轮毂的外部柔性轮毂，其中外部柔性轮毂适于连接到可以纵向不对准的管状轴。

8. 发明申请

US20100192412A1 SKATE BOOT WITH IMPROVED FLEXIBILITY 有权
标题翻译：具有改进灵活性的滑雪靴
公开(公告)号：US20100192412A1
公开(公告)日：2010-08-05
申请号：US12522718
申请日：2008-01-11
申请人： Andrew Stewart
发明人： Andrew Stewart
IPC分类号： A43B7/20 , A43D25/12
CPC分类号： A43B5/16 , A43B5/1691 , A43B7/18 , A43B7/20 , A63C1/42
摘要： A skate boot with a rear element that includes a tendon guard upwardly extending from an outsole of the boot is disclosed. The rear element covers at least a rear portion of an ankle received within the boot. The rear element has a base in connection with a heel portion of the outsole such that the rear element is displaceable relative a remainder of the boot in a forward and rearward direction about the connection. The rear element is an external element of the boot, and has a desired flexibility allowing the rear element to flex in the forward and rearward direction following a given forward and rearward flexion of the ankle.
摘要翻译：公开了一种具有后部元件的滑冰靴，其包括从靴子的外底向上延伸的腱护罩。后部元件覆盖在靴子内部接收的踝部的至少后部。后部元件具有与鞋外底的后跟部分相连的基部，使得后部元件相对于围绕连接件的向前和向后方向的保护罩的其余部分可移动。后部元件是护罩的外部元件，并且具有期望的柔性，允许后部元件沿着脚踝的给定的向前和向后弯曲在向前和向后方向上弯曲。

9. 发明申请

US20090260004A1 COMPUTER PROGRAM UPDATES FOR MOBILE COMPUTING DEVICE 审中-公开
标题翻译：移动计算机设备的计算机程序更新
公开(公告)号：US20090260004A1
公开(公告)日：2009-10-15
申请号：US12101004
申请日：2008-04-10
申请人： Mainak Datta , Andrew Stewart , James (Jianhua) Fan , Sateesh Krishna Shiradwade
发明人： Mainak Datta , Andrew Stewart , James (Jianhua) Fan , Sateesh Krishna Shiradwade
IPC分类号： G06F9/445
CPC分类号： H04L67/06 , G06F8/65 , H04L67/34 , H04M1/72525
摘要： A system and method for updating a computer program on a mobile computing device comprises uploading of packages to a repository, wherein each package comprises update data for a different portion of the computer program, a server identifying portions of the computer program to be updated on a device based on comparing information reported by the device and metadata about packages in the repository and a download server configured to wirelessly download the packages to the mobile computing device. The device may report back installation status to a server.
摘要翻译：一种用于在移动计算设备上更新计算机程序的系统和方法包括将包上传到存储库，其中每个包包括用于计算机程序的不同部分的更新数据，识别要更新的计算机程序的部分的服务器设备，其基于所述设备报告的信息和所述存储库中的包的元数据以及被配置为将所述包无线地下载到所述移动计算设备的下载服务器。设备可能会将安装状态报告给服务器。

10. 发明申请

US20060241282A1 Method of peptide synthesis 失效
标题翻译：肽合成方法
公开(公告)号：US20060241282A1
公开(公告)日：2006-10-26
申请号：US10566601
申请日：2004-07-30
申请人： Andrew Stewart
发明人： Andrew Stewart
IPC分类号： C07K14/52 , C07K1/02
CPC分类号： C07K1/042 , C07K14/521
摘要： A method for synthesizing a given peptide or its derivative which contains a proline residue or a proline derivative, at proximity to, or at, the C-terminal end of said peptide is provided. The method comprises a) synthesizing on a first resin a C-terminal portion of said peptide, or its derivative, comprising at least three successive amino acid residues or their derivatives, by successive coupling of selected amino acids, small peptides or their derivatives; b) cleaving the C-terminal portion from said first resin; c) reattaching said C-terminal portion to a second resin which is generally suitable for the synthesis of peptides but is unsuitable for the formation of peptides having a proline residue positioned at the C-terminal end of said peptide; and d) coupling selected amino acids, small peptides or derivatives to the C-terminal portion.
摘要翻译：提供了在所述肽的C-末端合成给定肽或其衍生物的方法，所述肽或其衍生物含有脯氨酸残基或脯氨酸衍生物，在所述肽的C末端附近或位置。该方法包括：a）通过连续偶联选择的氨基酸，小肽或其衍生物，在第一树脂上合成所述肽或其衍生物的C末端部分或其衍生物，其包含至少三个连续的氨基酸残基或其衍生物; b）从所述第一树脂切割C端部分; c）将所述C末端部分重新连接到通常适于合成肽的第二树脂，但不适于形成具有位于所述肽的C末端的脯氨酸残基的肽; 和d）将选择的氨基酸，小肽或衍生物偶联到C末端部分。

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