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    • 4. 发明申请
    • PROCESS FOR PREPARING SUBSTITUTED 2-ALKOXYCARBONYL-3-AMINOTHIOPHENES
    • 制备取代的2-烷氧羰基-3-氨基苯甲酸的方法
    • US20100004130A1
    • 2010-01-07
    • US11722506
    • 2005-12-14
    • Thomas Geller
    • Thomas Geller
    • A01N43/10C07D333/36
    • C07D333/38
    • The present invention relates to a process for preparing 4-alkoxycarbonyl-3-aminothiophenes of the general formula (I) and/or their hydrochlorides of the formula (I)′ in which R1 and R2 are each as defined in the description, and/or their mono- or bisacetylated or mono- or bisformylated form, by reacting enamines of the formula (II) in which R1 and R2 are each as defined in the description, and/or their mono- or bisacetylated or mono- or bisformylated form, with a chlorinating agent in the presence of one or more diluents, and also to a process for preparing the compounds of the formula (II).
    • 本发明涉及制备通式(I)的4-烷氧基羰基-3-氨基噻吩和/或式(I)'的盐酸盐的方法,其中R1和R2各自如说明书中所定义,和/ 或其单或双乙酰化或单或双甲酰化形式,其中式(II)的烯胺其中R 1和R 2各自如说明书中所定义,和/或其单乙酰化或双乙酰化或单或双甲酰化形式, 在一种或多种稀释剂的存在下使用氯化剂,以及制备式(II)化合物的方法。