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1. 发明申请

US20050209300A1 Methods of treating a disorder 审中-公开
标题翻译：治疗疾病的方法
公开(公告)号：US20050209300A1
公开(公告)日：2005-09-22
申请号：US10940269
申请日：2004-09-13
申请人： Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh , L. Huber , Jonathan Solomon , Russell Thomas , Jean-Francois Pons
发明人： Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh , L. Huber , Jonathan Solomon , Russell Thomas , Jean-Francois Pons
IPC分类号： A61K31/35 , A61K31/38 , A61K31/40 , A61K31/403 , A61K31/445 , C07D20060101
CPC分类号： A61K31/445 , A61K31/35 , A61K31/38 , A61K31/40 , A61K31/403 , C07D209/88
摘要： Compound of formula (I) and methods of treating disorders by administering a compound of formula (I) are described herein. Examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.
摘要翻译：本文描述式（I）化合物和通过施用式（I）化合物治疗病症的方法。病症的实例包括肿瘤性疾病，脂肪细胞相关疾病，神经变性疾病和代谢紊乱。

2. 发明申请

US20060074124A1 Methods of treating a disorder 审中-公开
标题翻译：治疗疾病的方法
公开(公告)号：US20060074124A1
公开(公告)日：2006-04-06
申请号：US11077664
申请日：2005-03-11
申请人： Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh , L. Huber , Jonathan Solomon , Russell Thomas , Jean-Francois Pons
发明人： Andrew Napper , Peter Distefano , Rory Curtis , Jeffrey Hixon , Thomas McDonagh , L. Huber , Jonathan Solomon , Russell Thomas , Jean-Francois Pons
IPC分类号： A61K31/403 , C07D209/82
CPC分类号： A61K31/403 , A61K31/404 , A61K31/437 , A61K31/4439 , A61K31/497 , A61K31/5377 , C07D209/18 , C07D209/88 , C07D209/94 , C07D471/04
摘要： Compound of formula (I) and methods of treating disorders by administering a compound of formula (I) are described herein. Examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders.
摘要翻译：本文描述式（I）化合物和通过施用式（I）化合物治疗病症的方法。病症的实例包括肿瘤性疾病，脂肪细胞相关疾病，神经变性疾病和代谢紊乱。

3. 发明申请

US20060051767A1 Cytochrome c acetylation 失效
公开(公告)号：US20060051767A1
公开(公告)日：2006-03-09
申请号：US10538823
申请日：2003-12-15
申请人： L Huber , Jonathan Solomon
发明人： L Huber , Jonathan Solomon
IPC分类号： C12Q1/68 , C12Q1/26
CPC分类号： C12Q1/48 , C07K14/80 , C12N9/80 , G01N33/5008 , G01N33/502 , G01N33/5079 , G01N33/5091 , G01N33/566 , G01N33/6872 , G01N2510/00
摘要： Modulation of cytochrome c acetylation, e.g., with a SIR polypeptide, enables interventions that modulate lifespan regulation and cell proliferation, e.g., by modulating apoptosis and/or mitochondrial function such as respiration.

4. 发明授权

US07800683B2 Optical method and system for enhancing image resolution 失效
标题翻译：用于增强图像分辨率的光学方法和系统
公开(公告)号：US07800683B2
公开(公告)日：2010-09-21
申请号：US10556385
申请日：2004-05-13
申请人： Zeev Zalevsky , Jonathan Solomon
发明人： Zeev Zalevsky , Jonathan Solomon
IPC分类号： H04N5/225
CPC分类号： G02B27/46 , G02B2207/129 , G06T5/003 , G06T5/10 , G06T11/001 , G06T2200/12 , G06T2207/20056 , H04N13/20
摘要： A method and system are presented for imaging an object with image resolution for at least a part of the object exceeding by a predetermined factor a geometrical resolution defined by a detector pixel array. A predetermined aperture coding is applied to the wavefront of a light signal indicative of at least a part of the object to be imaged with the enhanced resolution, while propagating towards the detector pixel array. The aperture coding is predetermined in accordance with aliasing occurring in the detector plane and such as to provide orthogonality of spectral data indicative of a sampled output of the detector, to thereby enable using the aperture code to reconstruct the image of said at least part of the object with the resolution enhanced by said factor.
摘要翻译：提出一种方法和系统，用于使具有图像分辨率的对象成像，所述物体的至少一部分超过预定因子，由检测器像素阵列定义的几何分辨率。当向检测器像素阵列传播时，预定的孔径编码被应用于指示要成像的对象的至少一部分的光信号的波前，具有增强的分辨率。孔径编码根据在检测器平面中出现的混叠而预先确定，并且提供指示检测器的采样输出的频谱数据的正交性，从而能够使用孔径码重建所述至少部分的图像对象的分辨率由所述因子增强。

5. 发明申请

US20070040828A1 Optical method and system for enhancing image resolution 失效
标题翻译：用于增强图像分辨率的光学方法和系统
公开(公告)号：US20070040828A1
公开(公告)日：2007-02-22
申请号：US10556385
申请日：2004-05-13
申请人： Zeev Zalevsky , Jonathan Solomon
发明人： Zeev Zalevsky , Jonathan Solomon
IPC分类号： G06T1/00
CPC分类号： G02B27/46 , G02B2207/129 , G06T5/003 , G06T5/10 , G06T11/001 , G06T2200/12 , G06T2207/20056 , H04N13/20
摘要： A method and system are presented for imaging an object with image resolution for at least a part of the object exceeding by a predetermined factor a geometrical resolution defined by a detector pixel array. A predetermined aperture coding is applied to the wavefront of a light signal indicative of at least a part of the object to be imaged with the enhanced resolution, while propagating towards the detector pixel array. The aperture coding is predetermined in accordance with aliasing occurring in the detector plane and such as to provide orthogonality of spectral data indicative of a sampled output of the detector, to thereby enable using the aperture code to reconstruct the image of said at least part of the object with the resolution enhanced by said factor.
摘要翻译：提出一种方法和系统，用于使具有图像分辨率的对象成像，所述物体的至少一部分超过预定因子，由检测器像素阵列定义的几何分辨率。当向检测器像素阵列传播时，预定的孔径编码被应用于指示要成像的对象的至少一部分的光信号的波前，具有增强的分辨率。孔径编码根据在检测器平面中出现的混叠而预先确定，并且提供指示检测器的采样输出的频谱数据的正交性，从而能够使用孔径码重建所述至少部分的图像对象的分辨率由所述因子增强。

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