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    • 3. 发明授权
    • Deactivation of organisms using high-intensity pulsed polychromatic light
    • 使用高强度脉冲多色光灭活生物
    • US06228332B1
    • 2001-05-08
    • US09025210
    • 1998-02-18
    • Joseph E. DunnReginald Wayne ClarkAndrew H. BushnellKenton J Salisbury
    • Joseph E. DunnReginald Wayne ClarkAndrew H. BushnellKenton J Salisbury
    • B01J1908
    • H01R13/639A23L3/26A61L2/08A61L2202/24C02F1/325C02F2201/3223C02F2201/3227C02F2201/3228C02F2201/328C02F2303/04H01R13/6215
    • A system of deactivating microorganisms in water involves illuminating the microorganisms using at least one short-duration, high-intensity pulse of broad-spectrum polychromatic light. The system includes a watertight housing having an inlet port and an outlet port for the flow water. A tubular light source for deactivating microorganisms and a tubular baffle for directing the water flow are positioned within the watertight housing. Waters enters the inlet port and flows between the watertight housing and the tubular baffle in one direction, around the end of the tubular baffle and back through the center of the tubular baffle in a second direction exiting the outlet port. In one embodiment, the inlet and outlet ports are positioned at the same end of the watertight housing. In a another embodiment, the inlet port is at the end of the watertight housing and the outlet port extends radially from the tubular baffle through the side of the watertight housing. Additionally, a removable recirculating hose may be connected from the inlet port to the outlet port for recirculating the water. A quartz jacket filled with a cooling material may be used around the tubular light source to provide cooling to the light source and spectral filtering of the light emitted from the light source. The inner surface of the baffle may be reflectorized to reflect light from the light source.
    • 使水中的微生物失活的系统包括使用至少一种具有广谱多色光的短持续时间的高强度脉冲来照射微生物。 该系统包括具有用于流动水的入口和出口的防水壳体。 用于使微生物灭活的管状光源和用于引导水流的管状挡板定位在防水壳体内。 水进入入口并在一个方向上在一个方向上在管状挡板之间流动,围绕管状挡板的端部,并沿离开出口的第二个方向返回经过管状隔板的中心。 在一个实施例中,入口和出口定位在防水外壳的同一端。 在另一个实施例中,入口端口处于水密壳体的端部,并且出口端口从管状挡板径向延伸穿过防水壳体的一侧。 此外,可移除的循环软管可以从入口端口连接到出口,用于再循环水。 可以在管状光源周围使用填充有冷却材料的石英套,以向光源提供冷却并对从光源发射的光进行光谱过滤。 挡板的内表面可以被反射,以反射来自光源的光。
    • 6. 发明授权
    • Parametric control in pulsed light sterilization
    • 脉冲光灭菌中的参数控制
    • US06566659B1
    • 2003-05-20
    • US09326168
    • 1999-06-04
    • Reginald Wayne ClarkJames C. LiermanDonald LanderJoseph E. Dunn
    • Reginald Wayne ClarkJames C. LiermanDonald LanderJoseph E. Dunn
    • B65B5508
    • A61L12/063A23L3/26A23L3/28A61L2/08A61L2/24A61L12/06A61L12/086B65B9/20B65B25/008B65B55/02B65B55/08B65B55/16
    • An approach for sterilizing microorganisms at a target object employs a flashlamp system including means for generating pulses of light, and for deactivating microorganisms within the target object by illuminating the target object with the pulses of light having been generated; a photo-sensitive detector positioned so as to receive a portion of each of the pulses of light as a measure of an amount of light illuminating the target object, for generating an output signal in response thereto; and a control system, coupled to the flashlamp system and the photo-sensitive detector, for determining, in response to the output signal, whether the pulses of light are sufficient to effect a prescribed level of deactivation of microorganisms at the target object. In accordance with this approach sterilizing microorganisms involves steps of generating a pulse of light; deactivating microorganisms at the target object by directing the pulse of light having been generated at the target object; receiving a portion of the pulse of light as a measure of an amount of the pulse of light illuminating the target object; generating an output signal in response to the receiving of the portion of the pulse of light; and determining, in response to the generating of the output signal, whether the pulse of light is sufficient to effect a prescribed level of deactivation of microorganisms at the target object.
    • 用于在目标物体上灭菌微生物的方法采用闪光灯系统,其包括用于产生光脉冲的装置,以及通过用已产生的光脉冲照射目标物体来使目标物体内的微生物失活; 光敏检测器,其被定位成接收每个所述脉冲的一部分作为照射所述目标物体的光量的量度,以响应于此产生输出信号; 以及耦合到所述闪光灯系统和所述光敏检测器的控制系统,用于响应于所述输出信号确定所述光脉冲是否足以影响所述目标对象处微生物的规定水平的失活。 根据这种方法,消毒微生物包括产生光脉冲的步骤; 通过引导已经在目标物体处产生的光的脉冲来使目标物体上的微生物失活; 接收光脉冲的一部分作为照射目标物体的光的脉冲量的量度; 响应于所述部分所述光脉冲的接收而产生输出信号; 以及响应于所述输出信号的产生,确定所述光脉冲是否足以影响所述目标对象处的微生物的规定的失活水平。
    • 7. 发明授权
    • Parametric control in pulsed light sterilization of packages and their
contents
    • 包装及其内容物的脉冲光灭菌中的参数控制
    • US5925885A
    • 1999-07-20
    • US846102
    • 1997-05-01
    • Reginald Wayne ClarkJames C. LiermanDonald LanderJoseph E. Dunn
    • Reginald Wayne ClarkJames C. LiermanDonald LanderJoseph E. Dunn
    • A23L3/26A23L3/28A61L2/08A61L2/24A61L12/06A61L12/08B65B25/00B65B55/02B65B55/08B65B55/16A61L2/10
    • A61L2/081A23L3/26A23L3/28A61L12/06A61L12/063A61L12/08A61L12/086A61L2/08A61L2/24B65B25/008B65B55/02B65B55/16A61L2202/14
    • An approach for sterilizing microorganisms at a target object employs a flashlamp system including means for generating pulses of light, and for deactivating microorganisms within the target object by illuminating the target object with the pulses of light having been generated; a photo-sensitive detector positioned so as to receive a portion of each of the pulses of light as a measure of an amount of light illuminating the target object, for generating an output signal in response thereto; and a control system, coupled to the flashlamp system and the photo-sensitive detector, for determining, in response to the output signal, whether the pulses of light are sufficient to effect a prescribed level of deactivation of microorganisms in the target object. In accordance with this approach sterilizing microorganisms involves steps of generating a pulse of light; deactivating microorganisms at the target object by directing the pulse of light having been generated at the target object; receiving a portion of the pulse of light as a measure of an amount of the pulse of light illuminating the target object; generating an output signal in response to the receiving of the portion of the pulse of light; and determining; in response to the generating of the output signal, whether the pulse of light is sufficient to effect a prescribed level of deactivation of microorganisms in the target object.
    • 用于在目标物体上灭菌微生物的方法采用闪光灯系统,其包括用于产生光脉冲的装置,以及通过用已产生的光脉冲照射目标物体来使目标物体内的微生物失活; 光敏检测器,其被定位成接收每个所述脉冲的一部分作为照射所述目标物体的光量的量度,以响应于此产生输出信号; 以及耦合到所述闪光灯系统和所述光敏检测器的控制系统,用于响应于所述输出信号确定所述光脉冲是否足以影响所述目标对象中微生物的规定水平的失活。 根据这种方法,消毒微生物包括产生光脉冲的步骤; 通过引导已经在目标物体处产生的光的脉冲来使目标物体上的微生物失活; 接收光脉冲的一部分作为照射目标物体的光的脉冲量的量度; 响应于所述部分所述光脉冲的接收而产生输出信号; 并确定; 响应于输出信号的产生,光的脉冲是否足以影响目标对象中的微生物的规定的失活水平。