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1. 发明申请

US20090214619A1 IMPLANT FOR INTRAOCULAR DRUG DELIVERY 审中-公开
标题翻译：内窥镜药物输送的植入物
公开(公告)号：US20090214619A1
公开(公告)日：2009-08-27
申请号：US12406876
申请日：2009-03-18
申请人： Andreas REIFF , Scott HAMPTON , Richard PAYNE
发明人： Andreas REIFF , Scott HAMPTON , Richard PAYNE
IPC分类号： A61F2/14 , A61K39/395 , A61K38/20
CPC分类号： A61K31/715 , A61F9/0017 , A61F2210/0004 , A61F2250/0068 , A61K9/0051 , C07K16/241
摘要： An implant for intraocular drug delivery for the treatment of inflammatory or degenerative diseases. In one embodiment, the implant includes a body portion having a first end portion and a second, opposite end portion and defining a cavity with a first opening at the first end portion, and a second, opposite opening at the second end portion, and a solid material received in the cavity, wherein the solid material comprises a depot material and an effective amount of at least one therapeutic compound or agent. When the implant is implanted in an eye of a living subject, the effective amount of at least one therapeutic compound or agent is released to the environment of the implant through at least one of the first opening and the second, opposite opening over an extended period of time.
摘要翻译：用于眼内药物递送的植入物用于治疗炎性或退行性疾病。在一个实施例中，植入物包括具有第一端部和第二相对端部并且在第一端部处限定具有第一开口的空腔的主体部分和在第二端部处的第二相对的开口，容纳在空腔中的固体材料，其中固体材料包含贮库材料和有效量的至少一种治疗化合物或药剂。当植入物植入生物体的眼睛中时，至少一种治疗化合物或药剂的有效量通过第一开口和第二相对开口中的至少一个在延长的时间段内释放到植入物的环境中的时间。

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