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1. 发明申请

US20090082457A1 DERIVATIVES OF N-(ARYLAMINO) SULFONAMIDES AS INHIBITORS OF MEK 有权
标题翻译：作为MEK的抑制剂的N-（ARYLAMINO）磺酰胺的衍生物
公开(公告)号：US20090082457A1
公开(公告)日：2009-03-26
申请号：US12323279
申请日：2008-11-25
申请人： Andreas MADERNA , Jean-Michel VERNIER , Dinesh BARAWKAR , Varaprasad CHAMAKURA , Hassan EL ABDELLAOUI , Zhi HONG
发明人： Andreas MADERNA , Jean-Michel VERNIER , Dinesh BARAWKAR , Varaprasad CHAMAKURA , Hassan EL ABDELLAOUI , Zhi HONG
IPC分类号： C07C311/14 , A61K31/18
CPC分类号： C07D417/04 , A61K31/18 , A61K31/34 , A61K31/381 , A61K31/40 , A61K31/415 , A61K31/4164 , A61K31/42 , A61K31/426 , A61K31/433 , A61K31/4406 , A61K31/4409 , A61K31/495 , A61K31/496 , A61K45/06 , C07B2200/07 , C07C311/08 , C07C311/09 , C07C311/10 , C07C311/14 , C07C311/21 , C07C311/28 , C07C311/29 , C07C311/32 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D207/36 , C07D211/54 , C07D213/38 , C07D213/42 , C07D231/12 , C07D231/18 , C07D233/84 , C07D261/10 , C07D277/36 , C07D277/54 , C07D285/04 , C07D295/088 , C07D295/13 , C07D307/64 , C07D333/34
摘要： This invention concerns N-(2-arylamino)aryl sulfonamides, which are inhibitors of MEK and are useful in treatment of cancer and other hyperproliferative diseases.
摘要翻译：本发明涉及作为MEK抑制剂的N-（2-芳基氨基）芳基磺酰胺，可用于治疗癌症和其它过度增生性疾病。

2. 发明申请

US20090238214A1 TIME SYNCHRONIZATION METHOD, TIME SYNCHRONIZATION EQUIPMENT AND NETWORK COMMUNICATION SYSTEM 审中-公开
标题翻译：时间同步方法，时间同步设备和网络通信系统
公开(公告)号：US20090238214A1
公开(公告)日：2009-09-24
申请号：US12470182
申请日：2009-05-21
申请人： Zhi HONG
发明人： Zhi HONG
IPC分类号： H04J3/06
CPC分类号： H04J3/0688 , H04J3/0641
摘要： A time synchronization method includes the following steps. First, network communication equipment receives time information sent by at least two time servers respectively, in which the time information includes time synchronization status information of each of the time servers. Then, it is determined whether time synchronization status of each of the time servers is normal or not according to the time synchronization status information. Finally, the network communication equipment selects to employ the time information provided by the time servers with the normal time synchronization status from the at least two time servers. Network communication equipment and a network communication system are also provided correspondingly. The network communication equipment is capable of employing the time information provided by the time server with the normal time synchronization status according to the time synchronization status of each of the time servers, thereby improving precision and reliability of the time information obtained by the network communication equipment.
摘要翻译：时间同步方法包括以下步骤。首先，网络通信设备分别接收由至少两个时间服务器发送的时间信息，其中时间信息包括每个时间服务器的时间同步状态信息。然后，根据时间同步状态信息确定每个时间服务器的时间同步状态是否正常。最后，网络通信设备选择采用来自至少两个时间服务器的具有正常时间同步状态的时间服务器提供的时间信息。网络通信设备和网络通信系统也相应提供。网络通信设备能够根据时间服务器的时间同步状态采用时间服务器提供的具有正常时间同步状态的时间信息，从而提高由网络通信设备获得的时间信息的精度和可靠性。

3. 发明申请

US20120225894A1 Substituted Thienol[2,3-d] pyrimidines as HIV Inhibitors 失效
标题翻译：取代的噻吩并[2,3-d]嘧啶作为HIV抑制剂
公开(公告)号：US20120225894A1
公开(公告)日：2012-09-06
申请号：US13470119
申请日：2012-05-11
申请人： Jean-Luc GIRARDET , Zhi HONG , Stephanie SHAW , Yung-hyo KOH
发明人： Jean-Luc GIRARDET , Zhi HONG , Stephanie SHAW , Yung-hyo KOH
IPC分类号： C07D495/04 , A61P31/18 , C12N5/00 , A61K31/519 , C12N7/06
CPC分类号： C07D495/04
摘要： This application concerns certain 4-cyanophenylamino-substituted bicyclic heterocycles of formula I where the dashed line represents a double bond that may be located either between A and C(V) or between C(V) and D, where A is S or C(Z); D is S or C(W); provided that one and only one of A and D is S; where T is NH, O, or S; and where other substituents are defined herein. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.
摘要翻译：本申请涉及式I的某些4-氰基苯基氨基取代的双环杂环，其中虚线表示可以位于A和C（V）之间或C（V）和D之间的双键，其中A是S或C（ Z）; D为S或C（W）; A和D中只有一个是S; 其中T是NH，O或S; 并且其中其它取代基在本文中定义。这些化合物是非核苷逆转录酶抑制剂，具有抗HIV治疗的潜力。

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