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1. 发明授权

US08834454B2 Drug delivery device 有权
标题翻译：给药装置
公开(公告)号：US08834454B2
公开(公告)日：2014-09-16
申请号：US12299602
申请日：2007-05-06
申请人： Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonathan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
发明人： Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonathan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
IPC分类号： A61K9/22 , A61M5/20 , A61M5/145 , A61M5/142 , A61M5/172
CPC分类号： A61M5/145 , A61M5/14248 , A61M5/14276 , A61M5/1452 , A61M5/14586 , A61M5/172 , A61M5/1723 , A61M5/2046 , A61M2005/14204 , A61M2005/14252 , A61M2005/14513 , A61M2205/35 , A61M2205/8206 , A61M2230/201 , H01M2/02 , H01M10/02 , H01M10/05 , H01M10/42 , H01M2220/30
摘要： The present application provides a drug-delivery device comprising a drug reservoir chamber 16, containing a substance to be delivered, in fluid connection with a drug administration means 18, and an electrically-controlled battery unit 10 comprising at least one displacement-generating battery cell 19 coupled to the drug reservoir chamber 16 by a coupling means 14, the arrangement being such that the displacement derived from the battery unit 10 is conveyed by the coupling means 14 to the drug reservoir chamber 16 such that the substance is expelled from the drug reservoir chamber 16 towards the drug administration means 18.
摘要翻译：本申请提供了一种药物递送装置，其包括药物储存室16，其包含与药物施用装置18流体连接的待递送物质，以及电控电池单元10，其包括至少一个位移产生电池单元 19通过联接装置14耦合到药物储存室16，该布置使得从电池单元10获得的位移被耦合装置14输送到药物储存室16，使得物质从药物储存器中排出腔室16朝向药物管理装置18。

2. 发明申请

US20100022992A1 Drug Delivery Device 有权
标题翻译：药物输送装置
公开(公告)号：US20100022992A1
公开(公告)日：2010-01-28
申请号：US12299602
申请日：2007-05-06
申请人： Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonothan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
发明人： Amir Genosar , Doron Aurbach , Elena Markevich , Grigory Salitra , Jonothan Goldstein , Mikhail Levi , Niles Fleischer , Yehuda Bachar , Yossi Aldar
IPC分类号： A61K9/22 , A61M37/00 , A61M1/00 , H01M2/02
CPC分类号： A61M5/145 , A61M5/14248 , A61M5/14276 , A61M5/1452 , A61M5/14586 , A61M5/172 , A61M5/1723 , A61M5/2046 , A61M2005/14204 , A61M2005/14252 , A61M2005/14513 , A61M2205/35 , A61M2205/8206 , A61M2230/201 , H01M2/02 , H01M10/02 , H01M10/05 , H01M10/42 , H01M2220/30
摘要： The present application provides a drug-delivery device comprising a drug reservoir chamber 16, containing a substance to be delivered, in fluid connection with a drug administration means 18, and an electrically-controlled battery unit 10 comprising at least one displacement-generating battery cell 19 coupled to the drug reservoir chamber 16 by a coupling means 14, the arrangement being such that the displacement derived from the battery unit 10 is conveyed by the coupling means 14 to the drug reservoir chamber 16 such that the substance is expelled from the drug reservoir chamber 16 towards the drug administration means 18.
摘要翻译：本申请提供了一种药物递送装置，其包括药物储存室16，其包含与药物施用装置18流体连接的待递送物质，以及电控电池单元10，其包括至少一个位移产生电池单元 19通过联接装置14耦合到药物储存室16，该布置使得从电池单元10获得的位移被耦合装置14输送到药物储存室16，使得物质从药物储存器中排出腔室16朝向药物管理装置18。

3. 发明授权

US07918843B2 Controllable drug delivery device 有权
标题翻译：可控药物输送装置
公开(公告)号：US07918843B2
公开(公告)日：2011-04-05
申请号：US12604278
申请日：2009-10-22
申请人： Amir Genosar , Jonathan Goldstein , Niles A. Fleisher , Yehuda Bachar , Yossi Aldar
发明人： Amir Genosar , Jonathan Goldstein , Niles A. Fleisher , Yehuda Bachar , Yossi Aldar
IPC分类号： A61K9/22 , A61M31/00
CPC分类号： A61M5/14248 , A61M5/14593 , A61M5/1486 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2205/0272
摘要： A controllable drug delivery device for delivering a liquid injectable drug, the device comprising a drug reservoir (22), a drug administration device (28), a displacement-generating battery (20), and a current-depletion circuit (85), wherein displacement generated by the battery as current is depleted from the battery by the current depletion circuit displaces a wall of the drug reservoir thereby causing the reservoir to expel liquid injectable drug contained therein via the drug administration device, and wherein the drug delivery device further includes a controller (78) that is responsive to a measured parameter indicative of displacement generated by the battery for applying a variable load (80) across the battery in order to provide a substantially constant-current depletion of the battery and thereby cause the drug delivery device to deliver a substantially constant drug delivery rate.
摘要翻译：一种用于输送液体可注射药物的可控药物递送装置，所述装置包括药物储存器（22），药物施用装置（28），置换产生电池（20）和耗尽电路（85），其中由于电流由电流消耗电路而从电池中耗尽的电池产生的位移使药物储存器的壁移位，从而使储存器经由药物给药装置排出其中所含的可注射液体，并且其中药物输送装置还包括：控制器（78），其响应于指示由电池产生的位移的测量参数，用于施加跨越电池的可变负载（80），以便提供电池的基本上恒定的电流消耗，从而使药物输送装置提供基本上恒定的药物递送率。

4. 发明申请

US20100087778A1 CONTROLLABLE DRUG DELIVERY DEVICE 有权
标题翻译：可控制药物递送装置
公开(公告)号：US20100087778A1
公开(公告)日：2010-04-08
申请号：US12604278
申请日：2009-10-22
申请人： Amir Genosar , Jonathan Goldstein , Niles A. Fleisher , Yehuda Bachar , Yossi Aldar
发明人： Amir Genosar , Jonathan Goldstein , Niles A. Fleisher , Yehuda Bachar , Yossi Aldar
IPC分类号： A61M5/168
CPC分类号： A61M5/14248 , A61M5/14593 , A61M5/1486 , A61M2005/14252 , A61M2005/14268 , A61M2005/14506 , A61M2205/0272
摘要： A controllable drug delivery device for delivering a liquid injectable drug, said device comprising a drug reservoir (22), a drug administration device (28), a displacement-generating battery (20), and a current-depletion circuit (85), wherein displacement generated by said battery as current is depleted from the battery by the current depletion circuit displaces a wall of the drug reservoir thereby causing the reservoir to expel liquid injectable drug contained therein via said drug administration device, and wherein the drug delivery device further includes a controller (78) that is responsive to a measured parameter indicative of displacement generated by the battery for applying a variable load (80) across the battery in order to provide a substantially constant-current depletion of said battery and thereby cause said drug delivery device to deliver a substantially constant drug delivery rate.
摘要翻译：一种用于输送液体可注射药物的可控药物递送装置，所述装置包括药物储存器（22），药物施用装置（28），排量产生电池（20）和耗尽电路（85），其中所述电池产生的位移由电流耗尽电路从电池中耗尽，使药剂贮存器的壁移位，从而使储存器经由所述药物给药装置排出其中所含的液体可注射药物，并且其中所述药物输送装置还包括控制器（78），其响应于指示由所述电池产生的位移的测量参数，以在所述电池上施加可变负载（80），以便提供所述电池的基本上恒定的电流消耗，从而使所述药物递送装置提供基本上恒定的药物递送率。

5. 发明授权

US09011376B2 Drug delivery device with electrically controlled volume changing means 有权
标题翻译：具有电控体积变化装置的药物输送装置
公开(公告)号：US09011376B2
公开(公告)日：2015-04-21
申请号：US11996468
申请日：2006-07-03
申请人： Amir Genosar , Jonathan Goldstein
发明人： Amir Genosar , Jonathan Goldstein
IPC分类号： A61M1/00 , A61M37/00 , A61M5/00 , A61K9/22 , A61M5/142 , A61M5/145 , A61B5/01 , A61B5/145 , A61B5/00 , A61M5/172
CPC分类号： A61M5/14244 , A61B5/01 , A61B5/14532 , A61B5/4839 , A61M5/14526 , A61M5/1454 , A61M5/14566 , A61M5/14593 , A61M5/1723 , A61M2005/14252 , A61M2005/14513 , A61M2230/201
摘要： The present invention provides a drug delivery device comprising a drug reservoir chamber (15) containing a substance (16) to be delivered in fluid connection with a drug administration means (17) and (18), and a hydraulic control chamber (9) containing an electrically controlled, non-gassing, volume changing means (13), a coupling means (14) coupling said hydraulic control chamber (9) to said drug chamber (15), the arrangement being such that a change in the electrical control means (11) causes a change in the volume of the volume changing means (13), the volume change being conveyed by the coupling means (14) to the drug chamber (15) such that the substance (16) is expelled from the drug chamber (15) towards the drug administration means (17) and (18).
摘要翻译：本发明提供了一种药物输送装置，其包括药物储存室（15），其包含与药物施用装置（17）和（18）流体连接地输送的物质（16），以及液压控制室（9），其包含电控制的非气体体积变化装置（13），将所述液压控制室（9）联接到所述药物室（15）的联接装置（14），所述装置使得电气控制装置 11）引起体积变化装置（13）的体积变化，体积变化由联接装置（14）输送到药物室（15），使得物质（16）从药物室排出 15）朝向药物施用装置（17）和（18）。

6. 发明申请

US20090093772A1 Drug Delivery Device with Electrically Controlled Volume Changing Means 有权
标题翻译：具有电控体积变化手段的药物输送装置
公开(公告)号：US20090093772A1
公开(公告)日：2009-04-09
申请号：US11996468
申请日：2006-07-03
申请人： Amir Genosar , Jonathan Goldstein
发明人： Amir Genosar , Jonathan Goldstein
IPC分类号： A61M5/142
CPC分类号： A61M5/14244 , A61B5/01 , A61B5/14532 , A61B5/4839 , A61M5/14526 , A61M5/1454 , A61M5/14566 , A61M5/14593 , A61M5/1723 , A61M2005/14252 , A61M2005/14513 , A61M2230/201
摘要： The present invention provides a drug delivery device comprising a drug reservoir chamber (15) containing a substance (16) to be delivered in fluid connection with a drug administration means (17) and (18), and a hydraulic control chamber (9) containing an electrically controlled, non-gassing, volume changing means (13), a coupling means (14) coupling said hydraulic control chamber (9) to said drug chamber (15), the arrangement being such that a change in the electrical control means (11) causes a change in the volume of the volume changing means (13), the volume change being conveyed by the coupling means (14) to the drug chamber (15) such that the substance (16) is expelled from the drug chamber (15) towards the drug administration means (17) and (18).
摘要翻译：本发明提供了一种药物输送装置，其包括药物储存室（15），其包含与药物施用装置（17）和（18）流体连接地输送的物质（16），以及液压控制室（9），其包含电控制的非气体体积变化装置（13），将所述液压控制室（9）联接到所述药物室（15）的联接装置（14），所述装置使得电气控制装置 11）引起体积变化装置（13）的体积变化，体积变化由联接装置（14）输送到药物室（15），使得物质（16）从药物室排出 15）朝向药物施用装置（17）和（18）。

7. 发明授权

US11759572B2 Aseptic cartridge and dispenser arrangement 有权
公开(公告)号：US11759572B2
公开(公告)日：2023-09-19
申请号：US13980200
申请日：2012-01-17
申请人： Amir Genosar
发明人： Amir Genosar
IPC分类号： B65D41/02 , A61M5/28 , A61M5/178 , A61M5/20 , A61M5/24 , A61J1/20 , A61M5/30 , A61M5/315 , A61M5/32 , A61M5/00 , A61M5/31
CPC分类号： A61M5/28 , A61J1/2093 , A61J1/2096 , A61M5/1782 , A61M5/2046 , A61M5/2066 , A61M5/2448 , A61M5/2455 , A61M5/30 , A61M5/31511 , A61M5/31596 , A61M5/3202 , A61M5/3213 , A61M5/3232 , A61J1/2024 , A61M5/002 , A61M2005/3104 , A61M2005/3118 , A61M2005/3121 , A61M2205/19
摘要： A cartridge for use with a beneficial agent delivery device having a fillable reservoir. The cartridge includes a reconstitution, unit dose package having first and second compartments and a fitment. The first compartment contains at least a first constituent of the beneficial agent. The second compartment contains at least a second constituent of the beneficial agent. The fitment is disposed on the package for interfacing the package to the fillable reservoir.

8. 发明授权

US10028886B2 Filing system and methods for aseptic cartridge and dispenser arrangement 有权
公开(公告)号：US10028886B2
公开(公告)日：2018-07-24
申请号：US14118470
申请日：2012-05-17
申请人： Amir Genosar
发明人： Amir Genosar
IPC分类号： B65D25/08 , A61J1/00 , A61J1/06 , A61J1/20 , B65D25/02 , A61J1/10 , A61J1/12 , A61J1/14 , B29C65/08 , B29C65/14 , B29C65/38 , B29C65/00 , B29C65/02 , B29C65/04 , B29C65/06 , B29L31/00
摘要： A package for use with a beneficial agent delivery device. The package includes at least one filling chamber having a sealed penetrable access region, at least one compartment configured to hold a content, wherein the content includes at least one of a beneficial agent or a constituent of a beneficial agent, and at least one channel connecting the at least one filling chamber in fluid communication with the at least one compartment. At least a portion of the package is resealable to contain the content.

9. 发明授权

US07524304B2 Drug infusion device 有权
标题翻译：药物输液装置
公开(公告)号：US07524304B2
公开(公告)日：2009-04-28
申请号：US10544167
申请日：2004-02-02
申请人： Amir Genosar
发明人： Amir Genosar
IPC分类号： A61M5/20
CPC分类号： A61M5/1454 , A61M5/14248 , A61M5/16804 , A61M2005/14204 , A61M2005/14513
摘要： The invention provides a drug delivery infusion device comprising an injection means (18) in fluid connection with a drug reservoir chamber (12) and pressure-generation means (10) coupled to both the drug reservoir (12) and to a liquid-filled control chamber (13), wherein the coupling is such that the liquid-filled control chamber (13) serves to constrain the motion of the pressure-generation means (10), thereby controlling the drug infusion rate, wherein the liquid-filled control chamber (13) is associated with means for controlled depletion of the liquid therein whereby depletion of the volume of liquid in the control chamber enables the pressure-generation means to drive the drug in the reservoir chamber therefrom for infusion thereof.
摘要翻译：本发明提供了一种药物递送输注装置，其包括与药物储存室（12）流体连接的注射装置（18）和联接到药物储存器（12）两者的压力产生装置（10）和与液体填充控制腔室（13），其中联接器使得充满液体的控制室（13）用于约束压力产生装置（10）的运动，从而控制药物输注速率，其中充满液体的控制室 13）与其中的液体的可控耗尽的装置相关联，由此在控制室中的液体体积的减少使得压力产生装置能够驱动储存室中的药物用于其输注。

10. 发明申请

US20070210113A1 Dispensing Container 审中-公开
标题翻译：分配容器
公开(公告)号：US20070210113A1
公开(公告)日：2007-09-13
申请号：US10578736
申请日：2004-11-09
申请人： Amir Genosar , Ilan Solomon
发明人： Amir Genosar , Ilan Solomon
IPC分类号： B65D37/00
CPC分类号： B05B11/3064 , B05B11/00412 , B05B11/3032 , B05B11/3077
摘要： The invention provides a container (10) having a dispensing outlet (19). A section of the container (10) adjacent to the outlet is provided with a pumping assembly (17) sized to be insertable into the section via the outlet and includes a pumping button (12). The button (12) is a section of the container wall (14) and depression of the button (12) actuates the pumping assembly (17).
摘要翻译：本发明提供一种具有分配出口（19）的容器（10）。所述容器（10）的与所述出口相邻的部分设置有泵送组件（17），所述泵组件（17）的尺寸设置成能够经由所述出口插入到所述部分中并且包括泵送按钮（12）。按钮（12）是容器壁（14）的一部分，并且按钮（12）的按压致动泵送组件（17）。

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