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1. 发明授权

US08722057B2 Method for producing β-carotene rich Dunaliella powder 有权
标题翻译：富含胡萝卜素的杜氏盐藻的生产方法
公开(公告)号：US08722057B2
公开(公告)日：2014-05-13
申请号：US13462003
申请日：2012-05-02
申请人： Ami Ben-Amotz , Nobuo Mori
发明人： Ami Ben-Amotz , Nobuo Mori
IPC分类号： A61K39/385 , C12N1/12 , A61K36/02
CPC分类号： A61K36/05 , A23L17/60 , A23L33/105 , A61K2236/331
摘要： In a step of producing a powder product of the alga belonging to the genus Dunaliella, a pH adjusting step is included in which an alga belonging to the genus Dunaliella is allowed to be in a basic state of pH 9.5 or higher. According to the method, it is possible to provide dried Dunaliella powder containing β-carotene at a high content by suppressing degradation of β-carotene as an active ingredient while decreasing each of the total pheophorbide amount and the existing pheophorbide amount to a predetermined value or less, even if the total pheophorbide amount and the existing pheophorbide amount of the cultured algae belonging to the genus Dunaliella are higher in summer.
摘要翻译：在制造属于杜氏盐藻属的藻类的粉末产物的步骤中，包括属于杜氏盐藻属的藻类处于pH9.5或更高的碱性状态的pH调节步骤。根据该方法，可以通过抑制β-胡萝卜素作为活性成分的降解，以高含量提供含有β-胡萝卜素的干燥杜氏盐藻粉，同时将总脱镁叶酸量和现有的脱镁叶酸量降低至预定的价值以下，即使属于杜氏盐藻属的培养藻类的总脱镁叶酸量和现存的偏磷酸盐量在夏季较高。

2. 植物专利

USPP4511P Alga strain 失效
公开(公告)号：USPP4511P
公开(公告)日：1980-03-18
申请号：US955007
申请日：1978-10-20
申请人： Mordhay Avron , Ami Ben-Amotz
发明人： Mordhay Avron , Ami Ben-Amotz
摘要： An alga named Dunaliella bardawil is similar to D. salina except that its length is 15-19 .mu.m, its diameter 10-14 .mu.m and its volume 200-1000 .mu.m.sup.3, and it contains large quantities of carotene and glycerol.

3. 发明授权

US4199895A Production of glycerol, carotenes and algae meal 失效
标题翻译：生产甘油，胡萝卜素和藻粉
公开(公告)号：US4199895A
公开(公告)日：1980-04-29
申请号：US918802
申请日：1978-06-26
申请人： Mordhay Avron , Ami Ben-Amotz
发明人： Mordhay Avron , Ami Ben-Amotz
IPC分类号： B04B5/10 , C12N1/12 , C12P7/20 , C12P23/00 , A01G7/00
CPC分类号： C07C403/24 , C12N1/12 , C12P23/00 , C12P7/20
摘要： According to the invention there is provided a process for the simultaneous production of glycerol, carotenes(.beta.-carotene, its isomers and carotene-like substances) and protein rich material which comprises cultivating algae of the Dunaliella bardawil species under high-intensity illumination in a growth medium containing a high concentration of sodium chloride (at least 1,5 M in the final stage of the cultivation), providing an adequate supply of carbon, in a depth of not exceeding 20 cm of the aqueous medium, in a diurnal cycle of illumination, until algae of high content of the above three components are obtained, harvesting the algae and recovering from same the three constituents.
摘要翻译：根据本发明，提供了一种同时生产甘油，胡萝卜素（β-胡萝卜素，其异构体和胡萝卜素样物质）和富含蛋白质的物质的方法，其包括在高强度照射下培养杜氏盐藻属物种的藻类含有高浓度氯化钠的生长培养基（在培养的最后阶段至少为1.5M），在不超过20cm的水介质的深度中提供足够的碳供应，在昼夜循环照射，直到获得上述三种成分的高含量的藻类，收获藻类并从其中回收三种成分。

4. 发明授权

US06383474B1 Carotenoid preparation 有权
标题翻译：类胡萝卜素制剂
公开(公告)号：US06383474B1
公开(公告)日：2002-05-07
申请号：US09786394
申请日：2001-05-18
申请人： Etienne Soudant , Lea Bezalel , Hedva Schickler , Judith Paltiel , Ami Ben-Amotz , Aviv Shaish , Inon Perry
发明人： Etienne Soudant , Lea Bezalel , Hedva Schickler , Judith Paltiel , Ami Ben-Amotz , Aviv Shaish , Inon Perry
IPC分类号： A61K742
CPC分类号： A61K31/01 , A23L33/105 , A23V2002/00 , A61K8/31 , A61K8/671 , A61K8/9706 , A61K31/015 , A61K2800/522 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61K2300/00 , A23V2250/211
摘要： A preparation comprising the carotenoids phytoene and phytofluene in an amount which, in combination, is effective in preventing various kinds of damage resulting from oxidation and exposure to UV light is provided. The preparation is essentially colorless and may be used as a topical cosmetic or pharmaceutical preparation as well as an additive in food preparations. In addition, a method for producing substantive amounts of phytoene and phytofluene from carotenoid producing organisms is described as well.
摘要翻译：提供了包含类胡萝卜素亚苄基和植物荧光素的制剂，其组合有效地防止由于氧化和暴露于紫外线而导致的各种损伤。该制剂基本上是无色的，并且可以用作局部化妆品或药物制剂以及食品制剂中的添加剂。此外，还描述了从产生类胡萝卜素的生物体产生大量的八氢番茄红素和植物荧光素的方法。

5. 发明授权

US4115949A Production of glycerol from algae 失效
标题翻译：从藻类生产甘油
公开(公告)号：US4115949A
公开(公告)日：1978-09-26
申请号：US800521
申请日：1977-05-25
申请人： Mordhay Avron , Ami Ben-Amotz
发明人： Mordhay Avron , Ami Ben-Amotz
IPC分类号： C12N1/00 , C12N1/12 , C12P7/20 , C12P21/00 , C12P23/00 , C12R1/89 , A01G7/00 , A01G33/02
CPC分类号： C12R1/89 , C12N1/12 , C12P23/00 , C12P7/20 , Y02P60/247
摘要： A process for the production of glycerol and proteinous substances of nutritive value which comprises cultivating algae of the Dunaliella species in a nutrient medium containing the mineral requirements of growth of the algae, said nutrient medium having a sodium chloride content of at least 1.5 M, the cultivation being effected while an adequate supply of carbon dioxide is provided and continued until a maximum concentration of algae is obtained, and continuing the cultivation of the algae in a nutrient medium having a content of sodium chloride of at least 3 M, cultivating the algae in this second nutrient medium until a high glycerol content is established, harvesting the algae, recovering from same the glycerol, and recovering the residue having a high protein content.
摘要翻译：一种用于生产营养价值的甘油和蛋白质物质的方法，其包括在含有藻类生长矿物质的营养培养基中培养杜氏盐藻藻类，所述营养培养基的氯化钠含量至少为1.5M，在充分供应二氧化碳的同时进行培养，并持续直到获得最大浓度的藻类，并且在含有至少3M氯化钠的营养培养基中继续培养藻类，培养藻类这种第二营养培养基直到建立高甘油含量，收获藻类，从甘油中回收，并回收具有高蛋白质含量的残余物。

6. 发明授权

US07482032B2 Carotenoid preparation 有权
公开(公告)号：US07482032B2
公开(公告)日：2009-01-27
申请号：US10097730
申请日：2002-03-14
申请人： Etienne Soudant , Lea Bezalel , Hedva Schickler , Judith Paltiel , Ami Ben-Amotz , Aviv Shaish , Inon Perry
发明人： Etienne Soudant , Lea Bezalel , Hedva Schickler , Judith Paltiel , Ami Ben-Amotz , Aviv Shaish , Inon Perry
IPC分类号： A23L3/00 , A23L1/30
CPC分类号： A61K31/01 , A23L33/105 , A23V2002/00 , A61K8/31 , A61K8/671 , A61K8/9706 , A61K31/015 , A61K2800/522 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61K2300/00 , A23V2250/211
摘要： A preparation comprising the carotenoids phytoene and phytofluene in an amount which, in combination, is effective in preventing various kinds of damage resulting from oxidation and exposure to UV light is provided. The preparation is essentially colorless and may be used as a topical cosmetic or pharmaceutical preparation as well as an additive in food preparations. In addition, a method for producing substantive amounts of phytoene and phytofluene from carotenoid producing organisms is described as well.

7. 发明授权

US5948823A Irradiation protection method 失效
标题翻译：照射保护方法
公开(公告)号：US5948823A
公开(公告)日：1999-09-07
申请号：US925657
申请日：1997-09-09
申请人： Ami Ben-Amotz , Zeev Weshler , Shaul Yatziv , Mordechai Sela
发明人： Ami Ben-Amotz , Zeev Weshler , Shaul Yatziv , Mordechai Sela
IPC分类号： A61K31/015 , A61K36/02 , A61K36/05 , A61P17/16 , A61K35/78
CPC分类号： A61K31/015 , A61K36/05
摘要： A method of protecting a mammal from the detrimental effects of irradiation is disclosed. The method comprises administering an effective amount of a substantially crude Dunaliella algae preparation to the mammal.
摘要翻译：公开了一种保护哺乳动物免受辐照的不利影响的方法。该方法包括向哺乳动物施用有效量的基本上粗的杜氏藻藻制剂。

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