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    • 2. 发明申请
    • VACUUM ASSISTED PERCUTANEOUS APPLIANCE
    • 真空辅助器具
    • US20120310181A1
    • 2012-12-06
    • US13394239
    • 2011-02-23
    • Allen B. KantrowitzChris MortisDaniel C. Wadsworth, JR.
    • Allen B. KantrowitzChris MortisDaniel C. Wadsworth, JR.
    • A61M1/00A61M25/00
    • A61M39/0247A61M25/00A61M25/0017A61M2025/006A61M2039/0261A61M2039/027A61M2039/0282
    • A device for reducing agent penetration at an insertion site is provided that has a porous inner sleeve fluidly connected to a conduit. A vacuum or hydrodynamic source is fluidly connected to the conduit. The device is stabilized by fibroblast in-growth and inhibits bacterial colonization. A device is also provided that has a conduit having a bore and an outer conduit surface. The outer conduit surface is optionally nanotextured to promote fibroblast adhesion and limit bacterial residency. A sleeve is provided in fluid communication with the bore of the conduit, and is formed from materials characterized by a pore matrix through which vacuum or hydrodynamic draw is achieved in a process to promote stabilization and reducing bacterial colonization by draw fluid from an area around the surrounding the site of the device. The sleeve optionally has a distal nanotextured surface.
    • 提供了一种用于在插入位置减少剂渗透的装置,其具有流体连接到导管的多孔内套筒。 真空或流体动力源流体连接到导管。 该装置通过成纤维细胞生长稳定并抑制细菌定植。 还提供了一种具有导管的装置,其具有孔和外导管表面。 外导管表面任选地纳米纹理以促进成纤维细胞粘附并限制细菌驻留。 提供与导管的孔流体连通的套筒,并且由具有孔基质的材料形成,通过该孔基体实现真空或流体动力学拉伸,以促进稳定化并通过从周围的区域抽取流体来减少细菌定殖 围绕设备的站点。 套筒任选具有远端纳米纹理表面。