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1. 发明授权

US08323336B2 Prosthetic heart valve devices and methods of valve replacement 有权
标题翻译：假体心脏瓣膜装置及瓣膜置换方法
公开(公告)号：US08323336B2
公开(公告)日：2012-12-04
申请号：US12429054
申请日：2009-04-23
申请人： Alexander J. Hill , Cynthia T. Clague , Carol Elsa Eberhardt , Ana R. Menk , Mark J. Capps , Billie J. Millwee , Janice Lynn Shay , Debra Ann Taitague , Joseph C. Morrow , Jerald Redmond
发明人： Alexander J. Hill , Cynthia T. Clague , Carol Elsa Eberhardt , Ana R. Menk , Mark J. Capps , Billie J. Millwee , Janice Lynn Shay , Debra Ann Taitague , Joseph C. Morrow , Jerald Redmond
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/24 , A61F2/2415 , A61F2/2418 , A61F2/2454 , A61F2/2457 , A61F2/2463 , A61F2/2487 , A61F2210/0014 , A61F2220/0016 , A61F2220/0075 , A61F2230/001 , A61F2230/0045 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0076 , A61F2230/008 , A61F2250/0039
摘要： A stented valve of two or more leaflets made of pericardium or other material having a relatively thin profile at the annulus. The leaflet surfaces are attached via chords to a stent frame, where the chords are positioned to mimic the native valve anatomy and functionality. In particular, the valves of one exemplary embodiment of the invention are sized to replace a mitral valve and therefore the chords are arranged to prevent prolapse of the leaflets into the atrium. The stented valve has a relatively short height at its annulus due to the positioning of the chords. In addition, the stented valve is capable of being crimped to a small enough size that it can be delivered to the implantation site via transcatheter delivery systems and methods.
摘要翻译：由心包或其他材料制成的两个或更多个传单的支架瓣膜，在瓣环处具有较薄的轮廓。小叶表面通过和弦连接到支架框架上，其中和弦被定位成模拟天然瓣膜解剖结构和功能。特别地，本发明的一个示例性实施例的阀的尺寸被设计成代替二尖瓣，并且因此设置弦杆以防止小叶向中庭脱垂。由于和弦的定位，支架瓣膜在其环形处具有相对短的高度。此外，支架瓣膜能够被卷曲到足够小的尺寸，使得其可以经由经导管递送系统和方法递送到植入部位。

2. 发明申请

US20090281618A1 Prosthetic Heart Valve Devices and Methods of Valve Replacement 有权
标题翻译：假体心脏瓣膜置换装置及方法
公开(公告)号：US20090281618A1
公开(公告)日：2009-11-12
申请号：US12429054
申请日：2009-04-23
申请人： Alexander J. Hill , Cynthia Clague , Carol Elsa Eberhardt , Ana R. Menk , Mark J. Capps , Billie J. Millwee , Janice Lynn Shay , Debra Ann Taitague , Joseph C. Morrow , Jerald Redmond
发明人： Alexander J. Hill , Cynthia Clague , Carol Elsa Eberhardt , Ana R. Menk , Mark J. Capps , Billie J. Millwee , Janice Lynn Shay , Debra Ann Taitague , Joseph C. Morrow , Jerald Redmond
IPC分类号： A61F2/06
CPC分类号： A61F2/2412 , A61F2/24 , A61F2/2415 , A61F2/2418 , A61F2/2454 , A61F2/2457 , A61F2/2463 , A61F2/2487 , A61F2210/0014 , A61F2220/0016 , A61F2220/0075 , A61F2230/001 , A61F2230/0045 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0076 , A61F2230/008 , A61F2250/0039
摘要： A stented valve of two or more leaflets made of pericardium or other material having a relatively thin profile at the annulus. The leaflet surfaces are attached via chords to a stent frame, where the chords are positioned to mimic the native valve anatomy and functionality. In particular, the valves of one exemplary embodiment of the invention are sized to replace a mitral valve and therefore the chords are arranged to prevent prolapse of the leaflets into the atrium. The stented valve has a relatively short height at its annulus due to the positioning of the chords. In addition, the stented valve is capable of being crimped to a small enough size that it can be delivered to the implantation site via transcatheter delivery systems and methods.
摘要翻译：由心包或其他材料制成的两个或更多个传单的支架瓣膜，在瓣环处具有较薄的轮廓。小叶表面通过和弦连接到支架框架上，其中和弦被定位成模拟天然瓣膜解剖结构和功能。特别地，本发明的一个示例性实施例的阀的尺寸被设计成代替二尖瓣，并且因此设置弦杆以防止小叶向中庭脱垂。由于和弦的定位，支架瓣膜在其环形处具有相对短的高度。此外，支架瓣膜能够被卷曲到足够小的尺寸，使得其可以经由经导管递送系统和方法递送到植入部位。

3. 发明申请

US20100114136A1 CUTTING DEVICE AND METHOD OF VESSEL HARVESTING 审中-公开
标题翻译：切割装置和船舶收集方法
公开(公告)号：US20100114136A1
公开(公告)日：2010-05-06
申请号：US12688028
申请日：2010-01-15
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/22
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a cutting device and method of vessel harvesting. The cutting device can include at least one tubular member, a cutting element, and a centering member. The cutting device can include at least one tubular member with a flexible section and a cutting element. The method of vessel harvesting can include spacing a cutting element of the cutting device from the vessel as the cutting element is advanced over the vessel.
摘要翻译：本发明的实施例提供一种切割装置和容器收获方法。切割装置可以包括至少一个管状构件，切割元件和定心构件。切割装置可以包括具有柔性部分和切割元件的至少一个管状部件。当切割元件在容器上前进时，容器收集的方法可以包括将切割装置的切割元件与容器间隔开。

4. 发明申请

US20080161843A1 Vessel support device and method of vessel harvesting 审中-公开
标题翻译：船舶支持装置和船舶采收方法
公开(公告)号：US20080161843A1
公开(公告)日：2008-07-03
申请号：US11974922
申请日：2007-10-16
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/32 , A61M5/00 , A61M31/00 , A61M5/178 , A61B19/00
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a vessel support system and a method of vessel harvesting. The system can include a cutting device, a catheter adapted to be inserted into a section of the vessel in order to support the vessel as the cutting device is advanced over the vessel, and a cannula adapted to be coupled to the vessel and adapted to receive the catheter as the catheter is inserted into the section of the vessel. The method can include orienting a cutting device coaxially with the cannula and the catheter and advancing the cutting device over the cannula, the catheter, and the section of the vessel in order to core out the section of the vessel and a portion of the surrounding tissue.
摘要翻译：本发明的实施例提供了一种血管支持系统和血管收集方法。该系统可以包括切割装置，适于插入到容器的一部分中的导管，以便当切割装置前进在容器上时支撑容器，以及适于联接到容器并适于接收的套管作为导管的导管插入血管的部分。该方法可以包括将切割装置与套管和导管同轴定向，并将切割装置推进套管，导管和容器的部分，以便将血管的一部分和周围组织的一部分。

5. 发明申请

US20080161841A1 Cutting device and method of vessel harvesting 审中-公开
标题翻译：切割装置和采集方法
公开(公告)号：US20080161841A1
公开(公告)日：2008-07-03
申请号：US11974914
申请日：2007-10-16
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/3205
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a cutting device and method of vessel harvesting. The cutting device can include at least one tubular member, a cutting element, and a centering member. The cutting device can include at least one tubular member with a flexible section and a cutting element. The method of vessel harvesting can include spacing a cutting element of the cutting device from the vessel as the cutting element is advanced over the vessel.
摘要翻译：本发明的实施例提供一种切割装置和容器收获方法。切割装置可以包括至少一个管状构件，切割元件和定心构件。切割装置可以包括具有柔性部分和切割元件的至少一个管状部件。当切割元件在容器上前进时，容器收集的方法可以包括将切割装置的切割元件与容器间隔开。

6. 发明申请

US20100121362A1 VESSEL SUPPORT DEVICE AND METHOD OF VESSEL HARVESTING 审中-公开
标题翻译：船舶支持装置和船舶收集方法
公开(公告)号：US20100121362A1
公开(公告)日：2010-05-13
申请号：US12689357
申请日：2010-01-19
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/22 , A61M25/00
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a vessel support system and a method of vessel harvesting. The system can include a cutting device, a catheter adapted to be inserted into a section of the vessel in order to support the vessel as the cutting device is advanced over the vessel, and a cannula adapted to be coupled to the vessel and adapted to receive the catheter as the catheter is inserted into the section of the vessel. The method can include orienting a cutting device coaxially with the cannula and the catheter and advancing the cutting device over the cannula, the catheter, and the section of the vessel in order to core out the section of the vessel and a portion of the surrounding tissue.
摘要翻译：本发明的实施例提供了一种血管支持系统和血管收集方法。该系统可以包括切割装置，适于插入到容器的一部分中的导管，以便当切割装置前进在容器上时支撑容器，以及适于联接到容器并适于接收的套管作为导管的导管插入血管的部分。该方法可以包括将切割装置与套管和导管同轴定向，并将切割装置推进套管，导管和容器的部分，以便将血管的一部分和周围组织的一部分。

7. 发明申请

US20130184727A1 VESSEL SUPPORT DEVICE AND METHOD OF VESSEL HARVESTING 审中-公开
标题翻译：船舶支持装置和船舶收集方法
公开(公告)号：US20130184727A1
公开(公告)日：2013-07-18
申请号：US12445919
申请日：2007-10-16
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Jolly , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Jolly , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/32
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a vessel support system and a method of vessel harvesting. The system can include a cutting device, a catheter adapted to be inserted into a section of the vessel in order to support the vessel as the cutting device is advanced over the vessel, and a cannula adapted to be coupled to the vessel and adapted to receive the catheter as the catheter is inserted into the section of the vessel. The method can include orienting a cutting device coaxially with the cannula and the catheter and advancing the cutting device over the cannula, the catheter, and the section of the vessel in order to core out the section of the vessel and a portion of the surrounding tissue.
摘要翻译：本发明的实施例提供了一种血管支持系统和血管收集方法。该系统可以包括切割装置，适于插入到容器的一部分中的导管，以便当切割装置前进在容器上时支撑容器，以及适于联接到容器并适于接收的套管作为导管的导管插入血管的部分。该方法可以包括将切割装置与套管和导管同轴定向，并将切割装置推进套管，导管和容器的部分，以便将血管的一部分和周围组织的一部分。

8. 发明申请

US20080167669A1 Vessel tensioning handle and method of vessel harvesting 审中-公开
标题翻译：船舶张紧手柄和船舶采收方法
公开(公告)号：US20080167669A1
公开(公告)日：2008-07-10
申请号：US11974906
申请日：2007-10-16
申请人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
发明人： Cynthia T. Clague , Michael J. Hobday , Raymond W. Usher , Roderick E. Briscoe , Katherine S. Olig , Ana R. Menk , Christopher P. Olig , Eric A. Meyer , Steven C. Christian , Thomas P. Daigle , Robert H. Reetz , Jeffrey D. Sandstrom , James R. Keogh , Matthew D. Bonner , Scott E. Jahns , Philip J. Haarstad
IPC分类号： A61B17/32 , A61B17/22
CPC分类号： A61B17/32 , A61B17/00008 , A61B17/3205 , A61B17/32053 , A61B2017/320064
摘要： Embodiments of the invention provide a vessel tensioning handle and method of placing tension on a section of a vessel being harvested. The handle can include a housing, a bobbin assembly, a vessel tensioning tape, and a tensioning device member. The tensioning device member can be coupled to a cannula that is coupled to the vessel. The method can include using the vessel tensioning tape to place tension on the section of the vessel as the cutting device is advanced over the vessel.
摘要翻译：本发明的实施例提供了一种容器张紧手柄和将张力放置在正在收获的容器的一部分上的方法。手柄可以包括壳体，筒管组件，容器张紧带和张紧装置构件。张紧装置构件可以联接到联接到容器的套管。该方法可以包括当切割装置在容器上前进时使用容器张紧带将张力放置在容器的部分上。

9. 发明授权

US08177735B2 Cardiotomy and venous blood reservoir and method 有权
标题翻译：心脏切开术和静脉血库及方法
公开(公告)号：US08177735B2
公开(公告)日：2012-05-15
申请号：US12372362
申请日：2009-02-17
申请人： Mark E. Wendler , Ana R. Menk , Eric R. Fox , Ningze Sun , Timothy D. Groen , Walt L. Carpenter
发明人： Mark E. Wendler , Ana R. Menk , Eric R. Fox , Ningze Sun , Timothy D. Groen , Walt L. Carpenter
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/3627 , A61M1/3632 , A61M39/0247
摘要： A cardiotomy and venous blood reservoir including a housing assembly, a downtube, and a bowl. The housing assembly forms a chamber. The downtube extends from an inlet port to a downstream end within the chamber. A diameter of the tube lumen increases to the downstream end. The bowl forms a floor surface shoulder, intermediate segment, and protrusion. The shoulder circumferentially surrounds, and is spatially above, the downstream end. The intermediate segment extends radially inwardly and downwardly from the shoulder to a bottom face. The protrusion extends radially inwardly and upwardly from the bottom face to a center that is aligned with the lumen and below the downstream end. The flared inner diameter of the lumen reduces fluid velocity as venous blood enters the reservoir. The bowl floor surface gently receives the incoming venous blood at the protrusion, and smoothly guides the blood flow.
摘要翻译：一种心切开和静脉血液储存器，包括壳体组件，下管和碗。壳体组件形成腔室。下管从入口端口延伸到腔室内的下游端。管腔的直径增加到下游端。碗形成地板表面肩部，中间部分和突起。肩部周向地包围并且在空间上在下游端。中间段从肩部径向向内和向下延伸到底面。突起从底面径向向内和向上延伸到与内腔对齐并在下游端下方的中心。当静脉血进入储存器时，管腔的扩口内径减少了流体速度。碗面表面轻轻地接收突出部位的输入静脉血，平稳地引导血流。

10. 发明授权

US08303529B2 Cardiotomy and venous blood reservoir and method 有权
标题翻译：心脏切开术和静脉血库及方法
公开(公告)号：US08303529B2
公开(公告)日：2012-11-06
申请号：US12770999
申请日：2010-04-30
申请人： Mark E. Wendler , Ana R. Menk , Eric R. Fox , Ningze Sun , Timothy D. Groen , Katherine S. Olig
发明人： Mark E. Wendler , Ana R. Menk , Eric R. Fox , Ningze Sun , Timothy D. Groen , Katherine S. Olig
IPC分类号： A61M37/00 , C02F1/44
CPC分类号： A61M1/3627 , A61M1/3632
摘要： A cardiotomy and venous blood reservoir, including a housing assembly, a venous inlet port, a venous sub-assembly, a cardiotomy inlet port, and a cardiotomy sub-assembly. The housing forms a chamber. The venous sub-assembly includes a downtube and a bowl. A diameter of the downtube lumen increases to a downstream end. The bowl forms a floor surface for receiving flow from the lumen. The cardiotomy sub-assembly includes a dish and an inner post. The dish defines an aperture. The inner post extends from the dish and forms a guide surface received within the central aperture and forming an undulating curvature increasing to a diameter greater than the diameter of the central aperture. Cardiotomy liquid drops from the dish fall on to the undulating, closely positioned guide surface with minimal splashing.
摘要翻译：一种心脏切开术和静脉血液储存器，包括壳体组件，静脉入口，静脉子组件，心脏切开术入口和心切开子组件。房屋形成一个房间。静脉分组件包括下管和碗。下管腔的直径增加到下游端。碗形成用于从内腔接收流动的地板表面。心脏切开术组件包括一个盘和一个内柱。该盘定义一个孔。内部柱从盘延伸并且形成容纳在中心孔内的引导表面并且形成增大到大于中心孔的直径的直径的起伏曲率。心脏切开术液滴从盘中落下到起伏较小的引导面上，飞溅少。

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