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1. 发明申请

US20070203396A1 Endoscopic Tool 审中-公开
标题翻译：内窥镜工具
公开(公告)号：US20070203396A1
公开(公告)日：2007-08-30
申请号：US11679635
申请日：2007-02-27
申请人： John McCutcheon , Antony Fields , Ronald Hundertmark , Michael Hendricksen , Michael Barrett , Alan Rapacki , Garrett Schwab
发明人： John McCutcheon , Antony Fields , Ronald Hundertmark , Michael Hendricksen , Michael Barrett , Alan Rapacki , Garrett Schwab
IPC分类号： A61B1/06
CPC分类号： A61B1/05 , A61B1/00082 , A61B1/00147 , A61B1/00179 , A61B1/00181 , A61B1/0051 , A61B1/2676 , A61B5/1076 , A61B18/02
摘要： Delivery system including endoscopes are described. In an embodiment, a delivery system includes a flexible, elongate endoscope extending along a longitudinal axis when the endoscope is straightened and a first lens located on the distal region. The first lens faces a direction transverse to the longitudinal axis. The first lens permits the endoscope to provide an image of anatomical structures that offset from the axis of the endoscope.
摘要翻译：描述包括内窥镜在内的输送系统。在一个实施例中，递送系统包括当内窥镜矫直时沿着纵向轴线延伸的柔性细长内窥镜和位于远侧区域上的第一透镜。第一透镜面向横向于纵轴的方向。第一透镜允许内窥镜提供从内窥镜的轴线偏移的解剖结构的图像。

2. 发明申请

US20080072914A1 Bronchial Isolation Devices for Placement in Short Lumens 审中-公开
标题翻译：用于在短流明中放置的支气管隔离装置
公开(公告)号：US20080072914A1
公开(公告)日：2008-03-27
申请号：US11844700
申请日：2007-08-24
申请人： Michael Hendricksen , Antony Fields , Michael Barrett , Ronald Hundertmark , Alan Rapacki , Steve Wallace , Michael Regan , John McCutcheon
发明人： Michael Hendricksen , Antony Fields , Michael Barrett , Ronald Hundertmark , Alan Rapacki , Steve Wallace , Michael Regan , John McCutcheon
IPC分类号： A62B9/02 , A61F2/04
CPC分类号： A61B17/12168 , A61B17/12022 , A61B17/12036 , A61B17/12104 , A61B17/12172 , A61B2017/1205 , A61F2/04 , A61F2/24 , A61F2002/043
摘要： Methods and devices are adapted for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.
摘要翻译：方法和装置适于调节流入和流出患者肺部区域的流体流动，例如在呼吸过程中实现期望的流体流动到肺部区域，和/或诱导一个或多个肺部区域的塌陷。根据示例性程序，确定的肺部区域被靶向用于治疗。然后将目标肺区域支气管分离，以通过一个或多个将空气送入目标肺部区域的支气管通路来调节进入和/或离开目标肺区域的气流。

3. 发明申请

US20060076023A1 Bronchial flow control devices and methods of use 审中-公开
标题翻译：支气管流量控制装置及使用方法
公开(公告)号：US20060076023A1
公开(公告)日：2006-04-13
申请号：US11289979
申请日：2005-11-29
申请人： Alan Rapacki , Michael Barrett
发明人： Alan Rapacki , Michael Barrett
IPC分类号： A62B9/06 , A61M16/00
CPC分类号： A61F2/04 , A61B17/12022 , A61B17/12036 , A61B17/1204 , A61B17/12104 , A61B17/12172 , A61B17/221 , A61B2017/1205 , A61B2017/12054 , A61B2090/061 , A61F2/06 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043 , A61F2220/0041 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0076 , A61F2230/0078 , A61F2230/0093 , F16K15/147 , Y10S128/912
摘要： A flow control device includes a sealing component that can be positioned within a bronchial lumen. The sealing component can comprise two or more overlapping segments that are movable relative to one another such that the segments collectively form a seal that can expand and contract in size to fit within and seal bronchial lumens of various sizes.
摘要翻译：流量控制装置包括可以位于支气管内腔内的密封部件。密封部件可以包括两个或更多个可相对于彼此移动的重叠部分，使得这些部分共同形成密封件，该密封件可以在尺寸上膨胀和收缩以装配并密封各种尺寸的支气管内腔并密封。

4. 发明申请

US20050145253A1 Bronchial flow control devices and methods of use 审中-公开
标题翻译：支气管流量控制装置及使用方法
公开(公告)号：US20050145253A1
公开(公告)日：2005-07-07
申请号：US11071850
申请日：2005-03-02
申请人： Peter Wilson , Antony Fields , Hanson Gifford , John McCutcheon , Michael Hendricksen , Alan Rapacki , David Tholfsen , Michael Barrett , Ronald Hundertmark , Douglas Sutton
发明人： Peter Wilson , Antony Fields , Hanson Gifford , John McCutcheon , Michael Hendricksen , Alan Rapacki , David Tholfsen , Michael Barrett , Ronald Hundertmark , Douglas Sutton
IPC分类号： A61B17/00 , A61B17/24 , A61F2/04 , A61F2/06 , A61F2/24 , A61M16/00 , A61M16/20 , A61M11/00 , A62B9/06
CPC分类号： A61F2/2412 , A61B2017/1205 , A61F2/04 , A61F2/06 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043 , A61F2002/9522 , Y10S128/912
摘要： Methods and systems for lung volume reduction of a patient are described. The methods include implanting a flow control device in a bronchial passageway of the lung. The flow control device regulates fluid flow through the bronchial passageway. A region of the lung is aspirated distal of the flow control device while the patient is inhaling.
摘要翻译：描述了患者肺容积减少的方法和系统。所述方法包括在肺的支气管通道中植入流量控制装置。流量控制装置调节通过支气管通道的流体流动。当患者正在吸入时，肺部的区域被吸入流量控制装置的远端。

5. 发明申请

US20050161048A1 Multiple seal port anesthesia adapter 有权
标题翻译：多重密封口麻醉适配器
公开(公告)号：US20050161048A1
公开(公告)日：2005-07-28
申请号：US11004560
申请日：2004-12-03
申请人： Alan Rapacki , Michael Barrett , Michael Hendricksen , Ronald Hundertmark
发明人： Alan Rapacki , Michael Barrett , Michael Hendricksen , Ronald Hundertmark
IPC分类号： A61M16/00 , A61M16/01 , A61M16/04 , A62B9/06
CPC分类号： A61M16/0463 , A61B2017/3466 , A61M16/01
摘要： Disclosed is an anesthesia adapter that is suitable for the simultaneous insertion of multiple devices or instruments into the lungs during ventilation of the patient, while minimizing or eliminating gas leaks. The anesthesia adapter comprises in one embodiment a first port sized to receive a first elongate instrument; a second port sized to receive a second elongate instrument; an endotrachial tube fitting configured to be coupled to an endotrachial tube, the endotrachial tube fitting fluidly coupled to the first and second ports; and a hose fitting configured to be coupled to a ventilator hose, the hose fitting fluidly coupled to the first and second ports. The first port seals around the first elongated instrument and the second port seals around the second elongate instrument.
摘要翻译：公开了一种麻醉适配器，其适合于在患者通气期间同时将多个装置或器械插入肺中，同时最小化或消除气体泄漏。麻醉适配器在一个实施例中包括尺寸适于接收第一细长器械的第一端口; 尺寸适于接纳第二细长仪器的第二端口; 构造成联接到血管内管的内窥镜管接头，所述内窥镜管配合流体耦合到所述第一和第二端口; 以及软管接头，其配置成联接到通气机软管，所述软管接头流体地联接到所述第一和第二端口。第一端口围绕第一细长器械密封，第二端口围绕第二细长器械密封。

6. 发明授权

US07011094B2 Bronchial flow control devices and methods of use 有权
公开(公告)号：US07011094B2
公开(公告)日：2006-03-14
申请号：US10627517
申请日：2003-07-25
申请人： Alan Rapacki , Michael Barrett
发明人： Alan Rapacki , Michael Barrett
IPC分类号： A62B9/00 , A61B9/06 , A61F2/06 , A61F2/04 , A61F11/00
CPC分类号： A61F2/04 , A61B17/12022 , A61B17/12036 , A61B17/1204 , A61B17/12104 , A61B17/12172 , A61B17/221 , A61B2017/1205 , A61B2017/12054 , A61B2090/061 , A61F2/06 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043 , A61F2220/0041 , A61F2230/005 , A61F2230/0054 , A61F2230/0067 , A61F2230/0076 , A61F2230/0078 , A61F2230/0093 , F16K15/147 , Y10S128/912
摘要： A flow control device includes a sealing component that can be positioned within a bronchial lumen. The sealing component can comprise two or more overlapping segments that are movable relative to one another such that the segments collectively form a seal that can expand and contract in size to fit within and seal bronchial lumens of various sizes.

7. 发明申请

US20060020347A1 Implanted bronchial isolation devices and methods 审中-公开
公开(公告)号：US20060020347A1
公开(公告)日：2006-01-26
申请号：US11075633
申请日：2005-03-08
申请人： Michael Barrett , Michael Hendricksen , Alan Rapacki , Ronald Hundertmark , Jeffrey Dolin , Robert George , John McCutcheon , Antony Fields
发明人： Michael Barrett , Michael Hendricksen , Alan Rapacki , Ronald Hundertmark , Jeffrey Dolin , Robert George , John McCutcheon , Antony Fields
IPC分类号： A61F2/04
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/12172 , A61F2/24 , A61F2/2412 , A61F2/2418 , A61F2/86 , A61F2/91 , A61F2002/043 , A61F2230/0054
摘要： Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.

8. 发明申请

US20050166925A1 Bronchial flow control devices and methods of use 有权
标题翻译：支气管流量控制装置及使用方法
公开(公告)号：US20050166925A1
公开(公告)日：2005-08-04
申请号：US11092123
申请日：2005-03-28
申请人： Peter Wilson , Antony Fields , Hanson Gifford , John McCutcheon , Michael Hendricksen , Alan Rapacki , David Tholfsen , Michael Barrett , Ronald Hundertmark , Douglas Sutton
发明人： Peter Wilson , Antony Fields , Hanson Gifford , John McCutcheon , Michael Hendricksen , Alan Rapacki , David Tholfsen , Michael Barrett , Ronald Hundertmark , Douglas Sutton
IPC分类号： A61B17/00 , A61B17/24 , A61F2/04 , A61F2/06 , A61F2/24 , A61M16/00 , A61M16/20 , A61M11/00
CPC分类号： A61F2/2412 , A61B2017/1205 , A61F2/04 , A61F2/06 , A61F2/2418 , A61F2/2427 , A61F2/91 , A61F2002/043 , A61F2002/9522 , Y10S128/912
摘要： Methods and systems for lung volume reduction of a patient are described. The methods include implanting a flow control device in a bronchial passageway of the lung. The flow control device regulates fluid flow through the bronchial passageway and includes a valve protector that at least partially surrounds a valve member. The valve protector has sufficient rigidity to maintain the shape of the valve member against compression.
摘要翻译：描述了患者肺容积减少的方法和系统。所述方法包括在肺的支气管通道中植入流量控制装置。流量控制装置调节通过支气管通道的流体流动并且包括至少部分地围绕阀构件的阀保护器。阀保护器具有足够的刚性以保持阀构件的形状不被压缩。

9. 发明授权

US08277830B2 Posterior segment drug delivery 有权
公开(公告)号：US08277830B2
公开(公告)日：2012-10-02
申请号：US13252998
申请日：2011-10-04
申请人： Eugene de Juan, Jr. , Yair Alster , Kathleen Cogan Farinas , Hanson S. Gifford, III , K. Angela MacFarlane , Cary J. Reich , Michael Barrett , Randolph E. Campbell , Douglas Sutton
发明人： Eugene de Juan, Jr. , Yair Alster , Kathleen Cogan Farinas , Hanson S. Gifford, III , K. Angela MacFarlane , Cary J. Reich , Michael Barrett , Randolph E. Campbell , Douglas Sutton
IPC分类号： A61M37/00 , A61M31/00
CPC分类号： G01N33/558 , A61F9/0017 , A61K9/0048 , A61K9/0051 , A61K31/57 , A61K31/573 , A61K31/58 , A61K38/385 , A61K47/32 , A61K47/34 , A61K47/38 , A61K2039/505 , C07K16/22 , C07K2317/24 , C07K2317/55 , Y10T29/49826
摘要： A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.

10. 发明申请

US20110010910A1 BRONCHIAL FLOW CONTROL DEVICES AND METHODS OF USE 有权
公开(公告)号：US20110010910A1
公开(公告)日：2011-01-20
申请号：US12820393
申请日：2010-06-22
申请人： Michael J. Hendricksen , Michael Barrett
发明人： Michael J. Hendricksen , Michael Barrett
IPC分类号： B23P11/00
CPC分类号： A61F2/04 , A61B17/12104 , A61B17/12172 , A61B17/12177 , A61F2002/043 , Y10T29/49826
摘要： Disclosed is an assembly for loading a bronchial flow control device into a container, such as into a delivery catheter. The assembly includes a funnel housing and a puller housing that mate with one another. The funnel housing defines a funnel-shaped loading cavity that receives a flow control device and that gradually reduces in size moving in a first direction. The puller housing is removably attached to the funnel housing and is also removably attachable to a bronchial flow control device that can be positioned in the loading cavity. The puller housing pulls the bronchial flow control device in the first direction through the funnel housing to gradually contract the bronchial flow control device into a compressed state of reduced size relative to the expanded size.
摘要翻译：公开了一种用于将支气管流量控制装置装载到诸如输送导管之类的容器中的组件。该组件包括一个漏斗壳体和一个相互配合的拔出器壳体。漏斗壳体限定漏斗形加载腔，其接纳流量控制装置，并逐渐减小尺寸沿第一方向移动。牵引器壳体可移除地附接到漏斗壳体，并且还可移除地附接到能够定位在加载腔中的支气管流量控制装置。牵引器壳体通过漏斗壳体沿着第一方向拉动支气管流量控制装置，以逐渐将支气管流量控制装置收缩成相对于膨胀尺寸减小尺寸的压缩状态。

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