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1. 发明授权

US4905698A Method and apparatus for catheter location determination 失效
标题翻译：用于导管位置确定的方法和装置
公开(公告)号：US4905698A
公开(公告)日：1990-03-06
申请号：US243689
申请日：1988-09-13
申请人： Clair L. Strohl, Jr. , Michael C. Ferragamo , Donald A. Kay , Alan R. Shapiro , Gary R. Whipple
发明人： Clair L. Strohl, Jr. , Michael C. Ferragamo , Donald A. Kay , Alan R. Shapiro , Gary R. Whipple
IPC分类号： A61B5/06 , A61M25/00 , A61M25/095
CPC分类号： A61B5/06
摘要： A method and apparatus (10) for determining accurately the location of the tip (14) of a catheter (16) inside biological tissue is disclosed including a locator (34) having a coil (38) wound axially on a core (36) and a detector (12) in the form of a coil (28) wound on a core (24) removably positionable within catheter (16) adjacent the tip (14). A controller (20) generates AC current to coil (38) to produce an electromagnetic field and compares it with the output voltage developed in coil ( b 28) when the locator (34) comes within close physical proximity to detecetor (12). Locator (34) includes an amber LED indicator (42) which is energized when the locator (34) is behind the detector (12) and the monitored output voltage is in phase with the generated alternating current and includes a red LED indicator (44) which is energized when the locator (34) is beyond the detector (12) and the monitored output voltage is 180.degree. out of phase with the generated alternating current. The controller (20) includes a beeper (48) which provides an audible indicator when energization changes between the indicators (42, 44).
摘要翻译：公开了一种用于准确地确定生物组织内的导管（16）的尖端（14）的位置的方法和装置（10），包括定位器（34），该定位器具有轴向地卷绕在芯部（36）上的线圈（38）卷绕在芯子（24）上的线圈（28）形式的检测器（12），其可拆卸地定位在邻近尖端（14）的导管（16）内。控制器（20）产生交流电流到线圈（38）以产生电磁场，并且当定位器（34）进入与物体接近检测器（12）时，与线圈（28）中产生的输出电压进行比较。定位器（34）包括琥珀色LED指示器（42），当定位器（34）位于检测器（12）后面时被激励，并且所监视的输出电压与产生的交流电流同相并且包括红色LED指示器（44）当定位器（34）超出检测器（12）并且所监视的输出电压与产生的交流电流相差180°时，其被通电。控制器（20）包括蜂鸣器（48），当在指示器（42,44）之间通电时，提供可听指示器。

2. 发明授权

US5425367A Catheter depth, position and orientation location system 失效
标题翻译：导管深度，位置和方向定位系统
公开(公告)号：US5425367A
公开(公告)日：1995-06-20
申请号：US755024
申请日：1991-09-04
申请人： Alan R. Shapiro , Donald A. Kay , Clair L. Strohl, Jr.
发明人： Alan R. Shapiro , Donald A. Kay , Clair L. Strohl, Jr.
IPC分类号： A61M25/00 , A61B5/06 , A61B19/00 , A61M25/095 , G01V3/10 , A61B5/05
CPC分类号： G01V3/105 , A61B5/06 , A61B2034/107 , A61B2034/2051 , A61B2090/3958 , A61B34/20 , H01F2005/027
摘要： A system for externally locating the depth and orientation of a catheter in tissue with an external probe which generates a virtual rotating magnetic field. The catheter includes an inductive coil for developing an induced signal in response to the virtual rotating magnetic field. An indicating device such as a light bar display or digital readout indicates the strength of the induced signal for locating, independently of the relative angular orientation of the probe and the catheter, the depth in the tissue of the catheter.
摘要翻译：用于外部定位导管在组织中的深度和取向的系统，该外部探针产生虚拟的旋转磁场。导管包括用于响应于虚拟旋转磁场显影感应信号的感应线圈。诸如光条显示器或数字读出器之类的指示装置指示用于定位的感应信号的强度，与探针和导管的相对角度取向无关，即导管组织中的深度。

3. 发明授权

US08197494B2 Medical device position guidance system with wireless connectivity between a noninvasive device and an invasive device 有权
标题翻译：医疗设备位置引导系统，在无创设备和侵入性设备之间具有无线连接
公开(公告)号：US08197494B2
公开(公告)日：2012-06-12
申请号：US11530385
申请日：2006-09-08
申请人： David S. Jaggi , Donald A. Kay , Joseph P. Killam , Salvatore Manzella, Jr. , King Y. Moy , David K. Platt , Shawn G. Purnell , Alan R. Shapiro , Michael C. Shaughnessy , Mark C. Witt , Christopher Zachara
发明人： David S. Jaggi , Donald A. Kay , Joseph P. Killam , Salvatore Manzella, Jr. , King Y. Moy , David K. Platt , Shawn G. Purnell , Alan R. Shapiro , Michael C. Shaughnessy , Mark C. Witt , Christopher Zachara
IPC分类号： A61B19/00
CPC分类号： A61B5/06 , A61B5/061 , A61B5/062 , A61B5/065 , A61B5/07
摘要： A medical device position guidance system having a noninvasive medical device communicable with an invasive medical device. The system provides outputs useful to assess the position of an invasive medical device in an animal, such as a human. A magnetic field is used to gather information about the position of the invasive device. Radio waves are used to communicate this information between the noninvasive device and the invasive device.
摘要翻译：一种医疗装置位置引导系统，其具有可与侵入性医疗装置通信的无创医疗装置。该系统提供有用的评估在诸如人类的动物中的侵入性医疗装置的位置的输出。使用磁场来收集关于侵入性装置的位置的信息。无线电波用于在无创设备和侵入性设备之间传送该信息。

4. 发明授权

US5645065A Catheter depth, position and orientation location system 失效
标题翻译：导管深度，位置和方向定位系统
公开(公告)号：US5645065A
公开(公告)日：1997-07-08
申请号：US420020
申请日：1995-04-11
申请人： Alan R. Shapiro , Donald A. Kay
发明人： Alan R. Shapiro , Donald A. Kay
IPC分类号： A61M25/00 , A61B5/06 , A61B19/00 , A61M25/095 , G01V3/10 , A61B5/05
CPC分类号： A61B5/06 , G01V3/105 , A61B2034/107 , A61B2034/2051 , A61B2090/062 , A61B2090/3958 , A61B34/20 , A61B34/25 , H01F2005/027
摘要： A system for externally locating a sensor in tissue, comprising an external probe including at least first and second electromagnetic output coils with non-parallel longitudinal axes; and output coil driver for alternately energizing the first and second output coils, for generating a time-varying magnetic field which penetrates the patient's skin; a sensor coil, having a longitudinal axis, for developing an induced electrical voltage in response to the time-varying magnetic field; a distance determinator, responsive to the induced voltage from the sensor coil, for determining from the induced voltage, the distance between the output coils and the sensor coil, independently of the relative angle, in a horizontal plane, between the sensor coil longitudinal axis, and the longitudinal axes of the output coils; and a direction determinator for determining and displaying the direction, in the horizontal plane, in which the sensor coil longitudinal axis is pointing.
摘要翻译：一种用于将传感器外部定位在组织中的系统，包括至少包括具有非平行纵向轴线的第一和第二电磁输出线圈的外部探头; 以及输出线圈驱动器，用于交替地激励第一和第二输出线圈，用于产生穿透患者皮肤的时变磁场; 传感器线圈，具有纵向轴线，用于响应于时变磁场而产生感应电压; 响应于来自传感器线圈的感应电压的距离确定器，用于根据感应电压确定输出线圈和传感器线圈之间的距离，独立于水平平面中在传感器线圈纵向轴线与传感器线圈之间的相对角度，和输出线圈的纵向轴线; 以及用于确定和显示传感器线圈纵向轴指向的水平面中的方向的方向确定器。

5. 发明授权

US09687174B2 Medical device position guidance system with wireless connectivity between a noninvasive and an invasive device 有权
公开(公告)号：US09687174B2
公开(公告)日：2017-06-27
申请号：US13472588
申请日：2012-05-16
申请人： David S. Jaggi , Donald A. Kay , Joseph P. Killam , Salvatore Manzella, Jr. , King Y. Moy , David K. Platt , Shawn G. Purnell , Alan R. Shapiro , Michael C. Shaughnessy , Mark C. Witt , Christopher Zachara
发明人： David S. Jaggi , Donald A. Kay , Joseph P. Killam , Salvatore Manzella, Jr. , King Y. Moy , David K. Platt , Shawn G. Purnell , Alan R. Shapiro , Michael C. Shaughnessy , Mark C. Witt , Christopher Zachara
IPC分类号： A61B5/06 , A61B5/07
CPC分类号： A61B5/06 , A61B5/061 , A61B5/062 , A61B5/065 , A61B5/07
摘要： A medical device position guidance system having a noninvasive medical device communicable with an invasive medical device. The system provides outputs useful to assess the position of an invasive medical device in an animal, such as a human. A magnetic field is used to gather information about the position of the invasive device. Radio waves are used to communicate this information between the noninvasive device and the invasive device.

6. 发明申请

US20080097475A1 MEDICAL DEVICE POSITION GUIDANCE SYSTEM WITH WIRELESS CONNECTIVITY BETWEEN A NONINVASIVE DEVICE AND AN INVASIVE DEVICE 有权
标题翻译：医疗器械位置指导系统与无创装置与入侵装置之间的无线连接
公开(公告)号：US20080097475A1
公开(公告)日：2008-04-24
申请号：US11530385
申请日：2006-09-08
申请人： David S. Jaggi , Donald A. Kay , Joseph P. Killam , Salvatore Manzella , King Y. Moy , David K. Platt , Shawn G. Purnell , Alan R. Shapiro , Michael C. Shaughnessy , Mark C. Witt , Christopher Zachara
发明人： David S. Jaggi , Donald A. Kay , Joseph P. Killam , Salvatore Manzella , King Y. Moy , David K. Platt , Shawn G. Purnell , Alan R. Shapiro , Michael C. Shaughnessy , Mark C. Witt , Christopher Zachara
IPC分类号： A61B19/00 , A61M5/00
CPC分类号： A61B5/06 , A61B5/061 , A61B5/062 , A61B5/065 , A61B5/07
摘要： A medical device position guidance system having a noninvasive medical device communicable with an invasive medical device. The system provides outputs useful to assess the position of an invasive medical device in an animal, such as a human. A magnetic field is used to gather information about the position of the invasive device. Radio waves are used to communicate this information between the noninvasive device and the invasive device.
摘要翻译：一种医疗装置位置引导系统，其具有可与侵入性医疗装置通信的无创医疗装置。该系统提供有用的评估在诸如人类的动物中的侵入性医疗装置的位置的输出。使用磁场来收集关于侵入性装置的位置的信息。无线电波用于在无创设备和侵入性设备之间传送该信息。

7. 发明申请

US20120226148A1 MEDICAL DEVICE POSITION GUIDANCE SYSTEM WITH WIRELESS CONNECTIVITY BETWEEN A NONINVASIVE AND AN INVASIVE DEVICE 有权
标题翻译：医疗器械位置指导系统与非侵入性和入侵设备之间的无线连接
公开(公告)号：US20120226148A1
公开(公告)日：2012-09-06
申请号：US13472588
申请日：2012-05-16
申请人： David S. Jaggi , Donald A. Kay , Joseph P. Killam , Salvatore Manzella, JR. , King Y. Moy , David K. Platt , Shawn G. Purnell , Alan R. Shapiro , Michael C. Shaughnessy , Mark C. Witt , Christopher Zachara
发明人： David S. Jaggi , Donald A. Kay , Joseph P. Killam , Salvatore Manzella, JR. , King Y. Moy , David K. Platt , Shawn G. Purnell , Alan R. Shapiro , Michael C. Shaughnessy , Mark C. Witt , Christopher Zachara
IPC分类号： A61M25/095 , A61B6/00
CPC分类号： A61B5/06 , A61B5/061 , A61B5/062 , A61B5/065 , A61B5/07
摘要： A medical device position guidance system having a noninvasive medical device communicable with an invasive medical device. The system provides outputs useful to assess the position of an invasive medical device in an animal, such as a human. A magnetic field is used to gather information about the position of the invasive device. Radio waves are used to communicate this information between the noninvasive device and the invasive device.
摘要翻译：一种医疗装置位置引导系统，其具有可与侵入性医疗装置通信的无创医疗装置。该系统提供有用的评估在诸如人类的动物中的侵入性医疗装置的位置的输出。使用磁场来收集关于侵入性装置的位置的信息。无线电波用于在无创设备和侵入性设备之间传送该信息。

8. 发明授权

US4743231A Drug administration needle unit 失效
标题翻译：给药针单位
公开(公告)号：US4743231A
公开(公告)日：1988-05-10
申请号：US70172
申请日：1987-07-06
申请人： Donald A. Kay , Per Troein
发明人： Donald A. Kay , Per Troein
IPC分类号： A61M5/158 , A61M39/02
CPC分类号： A61M39/0208 , A61M2005/1581 , A61M2039/0081 , A61M2205/195 , A61M2209/06 , Y10S128/26
摘要： A needle or cannula set especially adapted to access an implanted drug delivery portal includes a rigid base having a flat undersurface and a low profile. The base supports one end of a needle so that the needle projects from the base perpendicular to the base undersurface. One end of a flexible tube is secured to the base in fluid communication with the needle and the opposite end of the tube is terminated by a connector. A complaint pad is mounted to the base undersurface to assure proper seating of the base against the skin of the patient when the needle unit is inserted in the patient. The set also includes a handle which releasably connects to the base to facilitate inserting the needle unit into and withdrawing it from the patient and an adhesive dressing which is arranged to drape over the base with its edge margin extending all around the base for anchoring the needle unit to the patient and for providing an occlusive seal all around the puncture site. The set may also include a needle cover releasably coupled to the base to protectively enclose the needle and compliant pad prior to using the needle unit.
摘要翻译：特别适于接近植入药物递送入口的针或套管组件包括具有平坦的下表面和低轮廓的刚性基座。基部支撑针的一端，使得针垂直于底部下表面从基部突出。柔性管的一端固定到与针流体连通的基部，并且管的相对端由连接器终止。将投诉垫安装到底部底面上，以确保当针单元插入患者体内时基座抵靠患者皮肤的适当座位。该组件还包括可释放地连接到基座的手柄，以便于将针单元插入患者体内并将其从患者中取出;以及粘合剂敷料，其布置成悬垂在基部上，其边缘边缘围绕基部延伸以锚定针单元到患者并且在穿刺部位周围提供闭塞密封。该组件还可以包括可释放地联接到基座的针罩，以在使用针单元之前保护性地包围针和柔性衬垫。

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