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    • 1. 发明授权
    • Antineoplastic
5'-diacylglycerylphosphatidyl-2-deoxy-2'-methylenylcytidines and method
of making
    • 抗肿瘤性5'-二酰基甘油基磷脂酰基-2-脱氧-2'-亚甲基胞苷及其制备方法
    • US5696097A
    • 1997-12-09
    • US525606
    • 1995-09-15
    • Akira MatsudaTakuma SasakiSatoshi ShutouAkihiro FujiiTakashi OnoShinji SakataTakanori Miyashita
    • Akira MatsudaTakuma SasakiSatoshi ShutouAkihiro FujiiTakashi OnoShinji SakataTakanori Miyashita
    • C07H19/10A61K31/70C07H19/207
    • C07H19/10
    • Novel 2'-methylidenenucleotide compounds of the formula (I) ##STR1## wherein R is a hydrogen or a halogen, R.sup.1 and R.sup.2 are the same or different and each is a fatty acid residue or a hydrocarbon residue, and R.sup.3 and R.sup.4 are the same or different and each is a hydrogen, a halogen or an alkyl; salts thereof; methods for production thereof; and pharmaceutical use thereof. The compounds and salts thereof show an excellent antitumor effect in mammals. More specifically, they show a remarkable activity of inhibiting growth of mouse tumors, cultured human tumor cells, and human tumors transplanted to nude mice, and are useful for the treatment and prevention of recurrence of lung cancer, gastrointestinal cancer, breast cancer, cervical cancer, gynecological cancer, urinological cancer, leukemia, melanoma, lymphogenous metastatic tumor and the like in mammals. They are also useful as antitumor agents since they have an increased bioavailability and low toxicity. In addition, they have the effects of maintaining and enhancing their activities.
    • PCT No.PCT / JP94 / 00427 Sec。 371 1995年9月15日第 102(e)日期1995年9月15日PCT 1994年3月16日PCT公布。 第WO94 / 21659号公报 日期1994年9月29日新颖的式(I)的2'-亚甲基二核苷酸化合物其中R是氢或卤素,R 1和R 2相同或不同,各自为脂肪酸残基或烃 残基,R 3和R 4相同或不同,各自为氢,卤素或烷基; 的盐; 生产方法; 及其药物用途。 其化合物和盐在哺乳动物中表现出优异的抗肿瘤效果。 更具体地说,它们显示了抑制小鼠肿瘤,培养的人肿瘤细胞和移植到裸鼠的人肿瘤生长的显着活性,并且可用于治疗和预防肺癌,胃肠癌,乳腺癌,宫颈癌的复发 ,妇科癌症,尿毒症,白血病,黑素瘤,淋巴瘤转移瘤等。 它们也可用作抗肿瘤剂,因为它们具有增加的生物利用度和低毒性。 此外,它们还具有维护和增强活动的效果。
    • 2. 发明授权
    • Communication quality evaluation system, device, method, and program thereof
    • 通信质量评估系统,设备,方法和程序
    • US08675497B2
    • 2014-03-18
    • US12446903
    • 2007-11-20
    • Hiroto SugaharaTakashi Ono
    • Hiroto SugaharaTakashi Ono
    • H04J1/16H04M3/22
    • H04L1/24H04B17/0082H04B17/309
    • A communication quality evaluation system, a device, a method, and a program for evaluating communication quality at an arbitrary location, in the form which can actually felt by a user, are provided. According to an instruction from an evaluator, a control device displays a map or layout diagram of a specified area on a map/layout diagram display device and specifies an evaluation point within a display range of the map or the layout diagram. According to the network quality estimated by a network quality estimation unit, a network quality simulation unit for estimating the network quality when communications are performed at the evaluation point deteriorates the evaluation data and transmits the data to an evaluation device. The evaluation data deteriorated is a sample of data actually transmitted and received in the communication system. The evaluation device uses a communication device actually used by a user in the communication system.
    • 提供了以用户实际感觉到的形式来评估任意位置的通信质量的通信质量评估系统,设备,方法和程序。 根据评估者的指示,控制装置在地图/布局图显示装置上显示指定区域的地图或布局图,并在地图或布局图的显示范围内指定评价点。 根据由网络质量估计单元估计的网络质量,在评估点执行通信时估计网络质量的网络质量模拟单元劣化评估数据,并将该数据发送到评估装置。 评估数据恶化是在通信系统中实际发送和接收的数据的样本。 评估装置使用通信系统中的用户实际使用的通信装置。
    • 3. 发明授权
    • Aperture stop mechanism which drives two aperture blades and adjusts an aperture area of light passage opening into which light for imaging is introduced
    • 孔径停止机构,其驱动两个光圈叶片并调节光通路开口的孔径,其中引入用于成像的光
    • US08657510B2
    • 2014-02-25
    • US13512244
    • 2010-11-26
    • Hideaki MuramatsuTakashi Ono
    • Hideaki MuramatsuTakashi Ono
    • G03B9/02
    • G03B9/02
    • In an aperture stop mechanism, two aperture blades are arranged so as to overlap each other and form a single light passage opening into which light utilized in imaging is introduced with the respective edge portions of the two aperture blades. A drive mechanism drives the two aperture blades in directions different from each other, whereby the aperture area of the light passage opening is changed within a predetermined range. When the two aperture blades are located at a minimum aperture position where the aperture area of the light passage opening is minimum within the predetermined range, the two aperture blades are provided so that the single light passage opening surrounded by boundaries including eight straight lines is constituted of the respective edge portions of the two aperture blades.
    • 在孔径光阑机构中,两个孔径叶片被布置成彼此重叠,并且形成单个光通道开口,成像中使用的光与两个孔径叶片的相应边缘部分一起引入该开口中。 驱动机构沿彼此不同的方向驱动两个光圈叶片,由此光通道开口的开口面积在预定范围内变化。 当两个光圈叶片位于光通道开口的开口面积最小的最小孔径位置在预定范围内时,两个光圈叶片被设置成使由包括八条直线的边界包围的单个光通道开口构成 的两个孔径叶片的相应边缘部分。
    • 5. 发明授权
    • Webbing take-up device
    • 织带收卷装置
    • US08550394B2
    • 2013-10-08
    • US13116788
    • 2011-05-26
    • Takashi OnoAkira Sumiyashiki
    • Takashi OnoAkira Sumiyashiki
    • B65H75/48
    • B60R22/44
    • In an insertion hole formed in an adapter, a side wall which presses an insertion piece of a stopper with an urging force of a spiral spring has a wall surface parallel to a virtual straight line passing a center of the adapter and positioned on the virtual straight line. Thus, a direction which the wall surface of the side wall presses the insertion piece of the stopper is along a facing direction which the side wall and another side wall face each other, and is not inclined outward in a radial direction of the adapter with respect to the facing direction. Thereby, a pressing force applied from the wall surface of the side wall to the insertion piece of the stopper does not cause the insertion piece to be extruded from the insertion hole. Thus, insertion state of the insertion piece to the insertion hole can be satisfactorily maintained.
    • 在形成于适配器中的插入孔中,以螺旋弹簧的推压力挤压塞子的插入件的侧壁具有平行于通过适配器的中心并位于虚拟直线上的虚拟直线的壁面 线。 因此,侧壁的壁面按压止动件的插入件的方向是沿着侧壁和另一侧壁彼此面对的相对方向,并且不相对于适配器的径向向外倾斜 面向方向。 由此,从侧壁的壁面向止动件的插入片施加的按压力不会使插入片从插入孔挤出。 因此,可以令人满意地保持插入件到插入孔的插入状态。
    • 6. 发明授权
    • Fuel cell module
    • 燃料电池模块
    • US08507139B2
    • 2013-08-13
    • US13513432
    • 2010-12-21
    • Yasuhiro IzawaSatoshi ShiokawaTakashi OnoMitsuhiro Nakamura
    • Yasuhiro IzawaSatoshi ShiokawaTakashi OnoMitsuhiro Nakamura
    • H01M8/02H01M8/04H01M8/24
    • H01M8/04007H01M8/243H01M8/2457H01M8/2484
    • A fuel cell module includes in a casing: a fuel cell stack that is formed by stacking a plurality of unit cell; an oxidant gas distributing member that is disposed at a side surface, that extends in a stack direction of the unit cells, of the fuel cell stack that extends in a direction from one end to another end of each of the unit cells, and that supplies the oxidant gas to the another end of each unit cell after supplying the oxidant gas through the oxidant gas distributing member from the one end to the another end; a reformer disposed at the one end; and a combustion portion that is disposed between the one end and the reformer. The oxidant gas distributing member has a higher thermal conductivity at the one end side of the unit cells than at the another end side of the unit cells.
    • 燃料电池模块包括在壳体中:燃料电池堆,其通过堆叠多个单电池而形成; 一个氧化剂气体分配构件,其设置在燃料电池堆的沿单元电池的堆叠方向延伸的侧表面上,所述燃料电池堆在从每个单电池的一端到另一端的方向上延伸, 在从氧化剂气体分配构件的一端向另一端供给氧化剂气体后,将氧化剂气体输送到各单位电池的另一端; 一端设置的改质器; 以及设置在所述一端和所述重整器之间的燃烧部。 氧化剂气体分配构件在单元电池的一端侧具有比在单元电池的另一端侧更高的热导率。
    • 7. 发明授权
    • Seat back locking device for automobile
    • 汽车座椅靠背锁紧装置
    • US08393682B2
    • 2013-03-12
    • US12843185
    • 2010-07-26
    • Hirotsugu HosodaTakashi OnoTakefumi Mitsugi
    • Hirotsugu HosodaTakashi OnoTakefumi Mitsugi
    • B60N2/02
    • B60N2/366Y10T70/5982Y10T292/1047
    • A seat back locking device for an automobile for a seat back 5 configured so as to be capable of being changed from an upright position to a folded-down position and vice versa, including a locking mechanism 10 for locking the seat back 5 in the upright position, a locking knob 20 for unlocking the locking mechanism 10, and a key cylinder 30 capable of locking and unlocking the locking knob 20. In the locking device, a contact part 33 that comes into contact with a contacted part 26 provided on the locking knob 20 is connectingly provided integrally with a cylinder body 31 of the key cylinder 30 so that the key cylinder 30 can be changed over between a locked state in which the contact part 33 comes into contact with the contacted part 26 to inhibit the rotation of the locking knob 20 and an unlocked state in which the contact part 33 does not come into contact with the contacted part 26 to allow the rotation of the locking knob 20.
    • 一种用于座椅靠背5的座椅靠背锁定装置,其构造成能够从直立位置改变到折叠位置,反之亦然,包括用于将座椅靠背5锁定在直立件中的锁定机构10 位置,用于解锁锁定机构10的锁定旋钮20和能够锁定和解锁锁定旋钮20的键筒30.在锁定装置中,与设置在锁定上的接触部26接触的接触部33 旋钮20与键筒30的筒体31一体地连接设置,使得键筒30能够在接触部33与被接触部26接触的锁定状态之间切换,以阻止键筒30的旋转。 锁定旋钮20和解锁状态,其中接触部分33不与接触部分26接触以允许锁定旋钮20的旋转。
    • 8. 发明授权
    • Printing system, print processing method and program
    • 打印系统,打印处理方法和程序
    • US08363245B2
    • 2013-01-29
    • US11758827
    • 2007-06-06
    • Takashi Ono
    • Takashi Ono
    • G06F3/12
    • G06F3/1288
    • A printing system that adopts an SBC system in which a load at a server is alleviated when executing printing to enable printing to be performed smoothly. In the printing system, a client terminal, a server, and an image forming apparatus are connected to each other through a network. The client terminal specifies data among stored data in the server and sends a print execution request to the server. The server receives the print execution request, creates print-related information relating to the specified data, and sends it to the client terminal. The client terminal judges whether or not print data generation processing with respect to the specified data is possible at the client terminal based on the print-related information, and send the judgment result to the server. The server allocates the print data generation processing to either the server or the client terminal based on the judgment result.
    • 一种采用SBC系统的打印系统,其中在执行打印时减轻了服务器的负载,使打印顺利进行。 在打印系统中,客户终端,服务器和图像形成装置通过网络彼此连接。 客户终端指定服务器中存储的数据之间的数据,并向服务器发送打印执行请求。 服务器接收打印执行请求,创建与指定数据相关的打印相关信息,并发送给客户端。 客户终端基于打印相关信息判断在客户终端是否可以进行关于指定数据的打印数据生成处理,并将判断结果发送给服务器。 服务器根据判断结果将打印数据生成处理分配给服务器或客户终端。