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1. 发明授权

US4954438A Process for preparing antibiotics D788-7 失效
标题翻译：制备抗生素D788-7的方法
公开(公告)号：US4954438A
公开(公告)日：1990-09-04
申请号：US397061
申请日：1989-08-21
申请人： Akihiro Yoshimoto , Osamu Jodo , Yoshio Watanabe , Rokuro Okamoto , Tomio Takeuchi
发明人： Akihiro Yoshimoto , Osamu Jodo , Yoshio Watanabe , Rokuro Okamoto , Tomio Takeuchi
IPC分类号： C12P19/56 , A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P35/00 , C07H15/252 , C12R1/465
CPC分类号： C07H15/252 , Y10S435/886
摘要： This invention relates to a process for preparing an antibiotic D788-7 wherein, after culturing carborubicin-producing bacteria, the obtained culture liquid is extracted in acidic conditions while stirring to be absorbed to synthetic resin, followed by desorption from the resin and elution with acetone and the resulting acetone solution containing carborubicin is converted into an antibiotic D788-7 by photo radiation, for obtaining D788-7 in the purified form from the reaction solution. The production yield for D788-7 is extremely high and its use as an antitumor agent can be made possible.

2. 发明授权

US4918172A Anthracycline antibiotics 失效
标题翻译：蒽环类抗生素
公开(公告)号：US4918172A
公开(公告)日：1990-04-17
申请号：US252636
申请日：1988-10-03
申请人： Akihiro Yoshimoto , Osamu Jodo , Yoshio Watanabe , Rokuro Okamoto , Tomoyuki Ishikura , Hiroshi Naganawa , Tsutomu Sawa , Tomio Takeuchi
发明人： Akihiro Yoshimoto , Osamu Jodo , Yoshio Watanabe , Rokuro Okamoto , Tomoyuki Ishikura , Hiroshi Naganawa , Tsutomu Sawa , Tomio Takeuchi
IPC分类号： C07H15/252
CPC分类号： C07H15/252
摘要： Disclosed are anthracycline antibiotics of a formula (I): ##STR1## in which R.sup.1 and R.sup.2 are hydroxyl groups, R.sup.3 is ethyl group, R.sup.4 is methoxycarbonyl group and X represents daunosamine-rhodenose or daunosamine-deoxyfucose; orR.sup.1 and R.sup.2 are hydroxyl groups, R.sup.3 is 1-hydroxyethyl group, R.sup.4 is hydrogen atom and X represents daunosamine-rhodenose or daunosamine-deoxyfucose; orR.sup.1, R.sup.2 and R.sup.4 are hydroxyl groups, R.sup.3 is ethyl group and X represents daunosamine-rhodenose, daunosamine-deoxyfucose, rhodosamine-rhodenose, N-monomethyldaunosamine-rhodenose or N-monomethyldaunosamine-deoxyfucose; orR.sup.1 is methoxy group, R.sup.2 is hydroxyl group, R.sup.3 is ethyl group, R.sup.4 is methoxycarbonyl group and X represents daunosamine-rhodenose or daunosamine-deoxyfucose; orR.sup.1 and R.sup.4 are hydroxy groups, R.sup.2 is hydrogen atom, R.sup.3 is ethyl group and X represents daunosamine-deoxyfucose, as well as pharmaceutically acceptable acid addition salts thereof. The antibiotics (I) have a carcinostatic activity and are useful as a carcinostatic for murine leukemia L1210 cells in culture.

3. 发明授权

US4734493A Novel anthracycline antibiotics 失效
标题翻译：新型蒽环类抗生素
公开(公告)号：US4734493A
公开(公告)日：1988-03-29
申请号：US849229
申请日：1986-04-07
申请人： Akihiro Yoshimoto , Osamu Jodo , Yoshio Watanabe , Tomoyuki Ishikura , Tsutomu Sawa , Tomio Takeuchi , Hamao Umezawa
发明人： Akihiro Yoshimoto , Osamu Jodo , Yoshio Watanabe , Tomoyuki Ishikura , Tsutomu Sawa , Tomio Takeuchi , Hamao Umezawa
IPC分类号： A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P31/04 , A61P35/00 , C07H15/252 , C12P19/56 , C12R1/465 , C07H15/24
CPC分类号： C07H15/252
摘要： The antibiotics designated obelmycins exhibit high proliferation inhibiting action against leukemia cells and are effective as anti-cancer agents.
摘要翻译：称为替米yc嗪的抗生素对白血病细胞表现出高增殖抑制作用，作为抗癌剂是有效的。

4. 发明授权

US4897470A Anthracycline antibiotics DCP-1 and 2 失效
标题翻译：蒽环类抗生素DCP-1和2
公开(公告)号：US4897470A
公开(公告)日：1990-01-30
申请号：US34879
申请日：1987-04-06
申请人： Akihiro Yoshimoto , Osamu Jodo , Yoshio Watanabe , Tomoyuki Ishikura , Tsutomu Sawa , Tomio Takeuchi , Hamao Umezawa, deceased
发明人： Akihiro Yoshimoto , Osamu Jodo , Yoshio Watanabe , Tomoyuki Ishikura , Tsutomu Sawa , Tomio Takeuchi , Hamao Umezawa, deceased
IPC分类号： A61K31/70 , A61K31/7028 , A61K31/7034 , A61K31/704 , A61P35/00 , C07H15/252 , C12P29/00 , C12R1/465
CPC分类号： C07H15/252
摘要： New anthracycline antibiotics of a formula (I) are provided, which are usable as an anticancer agent ##STR1## (where R represents a hydrogen atom or a hydroxyl group). The antibiotics (I) can be produced by incubation of a dye-nonproductive or hardly dye-productive mutant strain which has an ability of converting .alpha.-citromycinone or .beta.-isorhodomycinone into the antibiotics (I), in the presence of .alpha.-citromycinone or .beta.-isorhodomycinone in a pertinent nutrient medium.

5. 发明授权

US5232943A Antibiotics Mer-AF1032A and Mer-AF1032B 失效
标题翻译：抗生素MER-AF1032A和MER-AF1032B
公开(公告)号：US5232943A
公开(公告)日：1993-08-03
申请号：US885771
申请日：1992-05-20
申请人： Hitosi Agematu , Yoshio Watanabe , Hiroyuki Chiba , Rei Kaneto , Norio Shibamoto , Takeo Yoshioka , Toshihiko Kumamoto , Hiroshi Nishida , Rokuro Okamoto
发明人： Hitosi Agematu , Yoshio Watanabe , Hiroyuki Chiba , Rei Kaneto , Norio Shibamoto , Takeo Yoshioka , Toshihiko Kumamoto , Hiroshi Nishida , Rokuro Okamoto
IPC分类号： C07D311/92 , C12P17/06 , C12R1/80
CPC分类号： C12P17/06 , C07D311/92
摘要： Antibiotic Mer-AF1032A represented by the following formula (I) and its isomer antibiotic Mer-AF1032B are disclosed. Also disclosed are a method for preparing the antibiotics comprising the cultivation of a strain belonging to genus Penicillium and a pharmaceutical composition comprising one of these antibiotics and useful as an antifungal agent. ##STR1##

6. 发明授权

US5223519A 4-hydroxypyridine derivatives, useful for treating circulatory diseases 失效
标题翻译： 4-羟基吡啶衍生物，有助于治疗循环疾病
公开(公告)号：US5223519A
公开(公告)日：1993-06-29
申请号：US830202
申请日：1991-12-13
申请人： Shin-ichi Hirano , Yoshio Watanabe , Kaichiro Kominato , Naoki Agata , Yutaka Hara , Norio Shibamoto , Takeo Yoshioka , Tomoyuki Kioka , Hiroshi Iguchi , Masataka Shirai , Hiroshi Tone , Rokuro Okamoto
发明人： Shin-ichi Hirano , Yoshio Watanabe , Kaichiro Kominato , Naoki Agata , Yutaka Hara , Norio Shibamoto , Takeo Yoshioka , Tomoyuki Kioka , Hiroshi Iguchi , Masataka Shirai , Hiroshi Tone , Rokuro Okamoto
IPC分类号： A61K31/44 , A61K31/4418 , A61P9/08 , C07D213/30 , C07D213/69 , C12P17/12 , C12R1/465
CPC分类号： C07D213/30 , C12P17/12
摘要： 4-Hydroxypyridine derivative represented by the following formula ##STR1## wherein R represents a methyl group or an isopropyl group, and the method for preparing the derivative comprising the step of cultivating a strain belonging to Streptomyces karnatakensis are disclosed. Also disclosed are the pharmaceutical composition comprising the same and a method for treating circulatory diseases comprising the step of administering said compound to a patient.

7. 发明授权

US08217276B2 Multilayer printed circuit board and method of manufacturing multilayer printed circuit board 失效
标题翻译：多层印刷电路板及多层印刷电路板制造方法
公开(公告)号：US08217276B2
公开(公告)日：2012-07-10
申请号：US10410434
申请日：2003-04-10
申请人： Kentaro Fujii , Yoshio Watanabe , Toru Takebe
发明人： Kentaro Fujii , Yoshio Watanabe , Toru Takebe
IPC分类号： H05K1/03
CPC分类号： H05K3/462 , H05K3/064 , H05K3/321 , H05K3/386 , H05K3/423 , H05K3/4623 , H05K3/4647 , H05K3/4658 , H05K2201/0195 , H05K2201/0355 , H05K2201/0394 , H05K2203/0733 , H05K2203/135 , Y10T29/49155 , Y10T29/49165
摘要： A multilayer printed circuit board which can surely establish interlayer connection with low resistance. The multilayer printed circuit board comprises: a first substrate having a conductive pattern on one face and a non-penetration connection hole on the other face, for exposing the conductive pattern to outside; a second substrate having a conductive pattern formed on a face opposed to the other face of first substrate and a conductive bump on the conductive pattern integrally. The first substrate and the second substrate are integrated by engaging the bump of the second substrate with the connection hole of the first substrate and by intervening a conductive cement between the bumps and the conductive pattern exposed to outside from the connection holes.
摘要翻译：一种多层印刷电路板，可以可靠地建立具有低电阻的层间连接。所述多层印刷电路板包括：在一个面上具有导电图案的第一基板和另一面上的非穿透连接孔，用于将导电图案暴露于外部; 第二基板，其具有形成在与第一基板的另一面相对的表面上的导电图案和导电图案上的导电凸块。第一基板和第二基板通过将第二基板的凸块与第一基板的连接孔接合并且通过在凸起和从连接孔露出到外部的导电图案之间插入导电粘合剂来集成。

8. 发明申请

US20100203842A1 Wireless communication terminal apparatus, wireless communication system and wireless communication method 审中-公开
标题翻译：无线通信终端装置，无线通信系统和无线通信方式
公开(公告)号：US20100203842A1
公开(公告)日：2010-08-12
申请号：US12671302
申请日：2008-07-30
申请人： Koichi Tachikawa , Yoshio Watanabe
发明人： Koichi Tachikawa , Yoshio Watanabe
IPC分类号： H04B1/38
CPC分类号： H04B7/061
摘要： A wireless communication terminal apparatus 10 is comprised of a plurality of antennas Ant1 and Ant2, a switch circuit 11 for switching to one selected antenna among the plurality of antennas Ant1 and Ant2, for carrying out a communication, and a control unit 14 for selecting another antenna among antennas in a non-selection status in response to the status of the reception signal, in a case where a status of a reception signal of an antenna in a selection status is not in the predetermined condition, and regardless a status of the reception signal of the antennas in a non-selection status, and controlling the switch circuit for making the switching of another antenna in a non-selection status at a transmission.
摘要翻译：无线通信终端装置10由多个天线Ant1和Ant2构成，切换电路11用于切换到多个天线Ant1和Ant2中的一个选定的天线，用于进行通信，以及控制单元14，用于选择另一天线在选择状态的天线的接收信号的状态不在预定条件的情况下，响应于接收信号的状态，处于非选择状态的天线之间的天线，并且不管接收的状态如何天线的信号处于非选择状态，并且控制开关电路，用于在另一个天线的切换中处于非选择状态。

9. 发明申请

US20060049130A1 Multilayer wiring board and process for fabricating a multilayer wiring board 失效
标题翻译：多层布线板及其制造方法
公开(公告)号：US20060049130A1
公开(公告)日：2006-03-09
申请号：US11212684
申请日：2005-08-29
申请人： Yoshio Watanabe
发明人： Yoshio Watanabe
IPC分类号： H01B13/00 , H05K1/00
CPC分类号： H05K3/4611 , H05K1/0218 , H05K1/0393 , H05K1/16 , H05K3/4614 , H05K3/4635 , H05K2201/055 , H05K2201/0715 , Y10T29/49135 , Y10T29/49155 , Y10T29/49165
摘要： A multilayer wiring board having a plurality of wiring layers is proposed, which is prepared by a process having the steps of: forming, on one insulating sheet, wiring patterns for all the wiring layers, which patterns are arranged at predetermined positions; and folding the insulating sheet having formed the wiring patterns in the predetermined order and stacking the folded sheet while positioning, and then heating the resultant sheet in a vacuum under a pressure to form a three-dimensional electric wiring.
摘要翻译：提出了具有多个布线层的多层布线板，其通过以下步骤制备：具有以下步骤的方法：在一个绝缘片上形成用于所有布线层的布线图案，哪些图案布置在预定位置; 并且以预定的顺序折叠形成布线图案的绝缘片并定位时堆叠折叠片，然后在压力下在真空中加热所得的片以形成三维电布线。

10. 发明授权

US06670757B2 Plasma display panel, method of manufacturing the same, and display device using the same 失效
标题翻译：等离子显示面板及其制造方法以及使用其的显示装置
公开(公告)号：US06670757B2
公开(公告)日：2003-12-30
申请号：US09358861
申请日：1999-07-22
申请人： Tetsuya Kato , Yoshio Watanabe , Hiroki Kono
发明人： Tetsuya Kato , Yoshio Watanabe , Hiroki Kono
IPC分类号： H01J1749
CPC分类号： H01J11/12 , H01J11/26 , H01J11/34 , H01J11/38 , H01J11/44 , H01J2211/444
摘要： A plasma display panel (“PDP”) is provided with a protrusion lower than barrier ribs on an inner surface of a back plate substrate, and a phosphor layer formed on a rib surface within a unitary emission unit including a surface of the protrusion, thereby realizing the PDP of high brightness, high luminous efficiency and long operating life. Also, the PDP has a structure, in which a portion of the inner surface of the substrate is opened to a discharge space directly or through a protective layer, so as to improve power consumption remarkably. Further, the invention provides a production of the PDP with superior whiteness by way of controlling a balance of each color with shape of the respective protrusions. Moreover, an electrode can be formed easily and precisely on an upper part of the protrusion by providing a sloped surface for at least one end in a longitudinal direction of the protrusion. As a result, the invention provides the PDP that is of low power consumption, high brightness, high luminous efficiency, and is capable of performing a speedy and stable electric-discharge and displaying white color of high color temperature.
摘要翻译：等离子体显示面板（“PDP”）在后板基板的内表面上设置有比阻挡肋低的突起，以及形成在包括突起的表面的单位发射单元内的肋表面上的荧光体层，由此实现高亮度，高发光效率和长使用寿命的PDP。此外，PDP具有这样的结构，其中基板的内表面的一部分直接或通过保护层向放电空间开放，从而显着地提高功耗。此外，本发明通过以各个突起的形状控制每种颜色的平衡来提供具有优异白度的PDP的生产。此外，通过为突起的纵向方向上的至少一端提供倾斜表面，可以在突起的上部容易且精确地形成电极。结果，本发明提供了低功耗，高亮度，高发光效率的PDP，能够进行快速稳定的放电和显示高色温的白色。

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