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1. 发明授权

US07982879B2 Methods and systems for performing angle-resolved fourier-domain optical coherence tomography 有权
标题翻译：用于进行角度分辨的傅里叶变换光学相干断层扫描的方法和系统
公开(公告)号：US07982879B2
公开(公告)日：2011-07-19
申请号：US11677278
申请日：2007-02-21
申请人： Adrien E. Desjardins , Benjamin J. Vakoc , Guillermo J. Tearney , Brett Eugene Bouma
发明人： Adrien E. Desjardins , Benjamin J. Vakoc , Guillermo J. Tearney , Brett Eugene Bouma
IPC分类号： G01B9/02
CPC分类号： G01N21/4795 , A61B5/0066 , A61B5/0073 , G01B9/02043 , G01B9/02087 , G01B9/02091 , G01B2290/70 , G01N2021/4714
摘要： Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro-magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third electro-magnetic radiations can be simultaneously detected, with the signals being associated with information for the sample at a plurality of depths thereof. The depths can be determined using at least one of the third electro-magnetic radiations without a need to utilize another one of the third electro-magnetic radiations.
摘要翻译：根据本发明的示例性实施例提供了安排，装置和方法。特别地，可以接收至少一个第一电磁辐射，并且将立体角内的至少一个第二电磁辐射转发到样品。第二电磁辐射可以与第一电磁辐射相关联。可以从与第二电磁辐射相关联的样品接收多个第三电磁辐射，并且第三电磁辐射的至少一部分设置在立体角的外围。可以同时检测与每个第三电磁辐射相关联的信号，其中信号与样品在其多个深度处的信息相关联。可以使用第三电磁辐射中的至少一个来确定深度，而不需要利用第三电磁辐射中的另一个。

2. 发明申请

US20070201033A1 METHODS AND SYSTEMS FOR PERFORMING ANGLE-RESOLVED FOURIER-DOMAIN OPTICAL COHERENCE TOMOGRAPHY 有权
标题翻译：用于执行角度决定的FOURIER-DOMAIN光学相干TOMOGRAPHY的方法和系统
公开(公告)号：US20070201033A1
公开(公告)日：2007-08-30
申请号：US11677278
申请日：2007-02-21
申请人： Adrien E. Desjardins , Benjamin J. Vakoc , Guillermo J. Tearney , Brett Eugene Bouma
发明人： Adrien E. Desjardins , Benjamin J. Vakoc , Guillermo J. Tearney , Brett Eugene Bouma
IPC分类号： G01B11/02
CPC分类号： G01N21/4795 , A61B5/0066 , A61B5/0073 , G01B9/02043 , G01B9/02087 , G01B9/02091 , G01B2290/70 , G01N2021/4714
摘要： Arrangements, apparatus and methods are provided according to exemplary embodiments of the present invention. In particular, at least one first electro-magnetic radiation may be received and at least one second electro-magnetic radiation within a solid angle may be forwarded to a sample. The second electro-magnetic radiation may be associated with the first electro-magnetic radiation. A plurality of third electro-magnetic radiations can be received from the sample which is associated with the second electro-magnetic radiation, and at least one portion of the third electro-magnetic radiation is provided outside a periphery of the solid angle. Signals associated with each of the third electro-magnetic radiations can be simultaneously detected, with the signals being associated with information for the sample at a plurality of depths thereof. The depths can be determined using at least one of the third electro-magnetic radiations without a need to utilize another one of the third electro-magnetic radiations.
摘要翻译：根据本发明的示例性实施例提供了安排，装置和方法。特别地，可以接收至少一个第一电磁辐射，并且将立体角内的至少一个第二电磁辐射转发到样品。第二电磁辐射可以与第一电磁辐射相关联。可以从与第二电磁辐射相关联的样品接收多个第三电磁辐射，并且第三电磁辐射的至少一部分设置在立体角的外围。可以同时检测与每个第三电磁辐射相关联的信号，其中信号与样品在其多个深度处的信息相关联。可以使用第三电磁辐射中的至少一个来确定深度，而不需要利用第三电磁辐射中的另一个。

3. 发明申请

US20110201922A1 OPTICAL PROBE HAVING A POSITION MEASURING SYSTEM 有权
标题翻译：具有位置测量系统的光学探头
公开(公告)号：US20110201922A1
公开(公告)日：2011-08-18
申请号：US13125812
申请日：2009-10-21
申请人： Cornelis A. Hezemans , Bernardus H.W. Hendriks , Waltherus C.J. Bierhoff , Augustinus L. Braun , Adrien E. Desjardins
发明人： Cornelis A. Hezemans , Bernardus H.W. Hendriks , Waltherus C.J. Bierhoff , Augustinus L. Braun , Adrien E. Desjardins
IPC分类号： A61B5/05
CPC分类号： A61B1/00188 , A61B1/00096 , A61B1/00163 , A61B1/00165 , A61B5/0062 , A61B5/0084 , A61B5/061 , A61B5/062 , A61B5/065 , A61B34/73 , A61B90/361 , A61B2034/2051
摘要： This invention relates to an optical probe (200) and an optical imaging system, including an optical guide (201) having a proximal end and a distal end, an actuation means having driving coils (204) and a magnet, with of which being attached to the optical guide. By supplying a driving current through the driving coils a magnetic flux is generated which interacts with the magnet forming a driving force acting at on the optical guide causing a displacement of the distal end of the optical guide. A position measuring including a position measuring coil (205) is used for monitoring the position of the optical guide, where the internal arrangement of the position measuring coil and the driving coils is such that said displacement of the distal end of the optical guide causes a change in the internal arrangement. A power supply supplies an additional high frequency alternating current (AC) through the driving coils which causes an induced voltage in the position measuring coil and thus generates a magnetic coupling between the position measuring coil and the driving coils. A position measuring means measures the displacement of the distal end of the optical guide by means of measuring the induced voltage resulting in when the internal arrangement changes. This induced voltage change being indicative for the position of the distal end.
摘要翻译：本发明涉及一种光学探针（200）和光学成像系统，其包括具有近端和远端的光导（201），具有驱动线圈（204）和磁铁的致动装置到光导。通过提供驱动电流通过驱动线圈产生与磁体相互作用的磁通，形成作用在光导上的驱动力，导致光导的远端位移。包括位置测量线圈（205）的位置测量用于监测光导的位置，其中位置测量线圈和驱动线圈的内部布置使得光导的远端的所述位移导致改变内部安排。电源通过驱动线圈提供额外的高频交流电，这导致位置测量线圈中的感应电压，从而在位置测量线圈和驱动线圈之间产生磁耦合。位置测量装置通过测量导致当内部布置改变的感应电压来测量光导的远端的位移。该感应电压变化指示远端的位置。

4. 发明授权

US08977343B2 Optical probe having a position measuring system 有权
标题翻译：光探头具有位置测量系统
公开(公告)号：US08977343B2
公开(公告)日：2015-03-10
申请号：US13125812
申请日：2009-10-21
申请人： Cornelius A. Hezemans , Bernardus H. W. Hendriks , Waltherus C. J. Bierhoff , Augustinus L. Braun , Adrien E. Desjardins
发明人： Cornelius A. Hezemans , Bernardus H. W. Hendriks , Waltherus C. J. Bierhoff , Augustinus L. Braun , Adrien E. Desjardins
IPC分类号： A61B18/14 , G01B7/00 , A61B1/00 , A61B5/00 , A61B5/06 , A61B19/00
CPC分类号： A61B1/00188 , A61B1/00096 , A61B1/00163 , A61B1/00165 , A61B5/0062 , A61B5/0084 , A61B5/061 , A61B5/062 , A61B5/065 , A61B34/73 , A61B90/361 , A61B2034/2051
摘要： An optical probe and an optical imaging system include an optical guide, and an actuator having driving coils and a magnet. By supplying a driving current through the driving a magnetic flux is generated which causes a displacement of the distal end of the optical guide. A position measuring device includes a position measuring coil used for monitoring the position of the optical guide, where displacement of the guide distal end causes change in the relative positions of the measuring and driving coils. A power supply supplies a high frequency AC current through the driving coils which causes, an induced voltage in the position measuring coil and thus generates a magnetic coupling between the measuring and driving coils. This induced voltage change is indicative for the position of the distal end.
摘要翻译：光学探针和光学成像系统包括光导和具有驱动线圈和磁体的致动器。通过提供通过驱动的驱动电流，产生导致光导的远端位移的磁通。位置测量装置包括用于监测光导的位置的位置测量线圈，其中导向器远端的位移导致测量和驱动线圈的相对位置的变化。电源通过驱动线圈提供高频AC电流，这导致位置测量线圈中的感应电压，从而在测量和驱动线圈之间产生磁耦合。该感应电压变化表示远端的位置。

5. 发明申请

US20090143686A1 OPTICAL COHERENT TOMOGRAPHY DIAGNOSTIC APPARATUS 有权
标题翻译：光学相干诊断设备
公开(公告)号：US20090143686A1
公开(公告)日：2009-06-04
申请号：US12274991
申请日：2008-11-20
申请人： Yuuji ONIMURA , Adrien E. Desjardins
发明人： Yuuji ONIMURA , Adrien E. Desjardins
IPC分类号： A61B6/00 , G01B9/02
CPC分类号： A61B5/0073 , A61B5/0062 , A61B5/0066 , A61B5/0084
摘要： An optical coherent tomography diagnostic apparatus including: a light source; a splitter for splitting the light outputted from the light source into a measuring light and a reference light; a measuring light path; a reference light path; a probe inserted into a body cavity and emitting the measuring light to a subject of measurement; an image forming unit for calculating intensity distribution of the reflection light and for forming a tomographic image; a standard light path for transmitting standard light obtained by further splitting the light; wherein the light path length when exerting interference between the standard light and the reference light is approximately equal to the light path length when exerting interference between the reference light and the reflection light, and there is included a calculation unit for calculating time change of coherent light data obtained by exerting interference between the standard light and the reference light.
摘要翻译：一种光学相干断层摄影诊断装置，包括：光源; 分离器，用于将从光源输出的光分成测量光和参考光; 测光路; 参考光路; 插入体腔中并将测量光发射到测量对象的探针; 图像形成单元，用于计算反射光的强度分布和用于形成断层图像; 用于传送通过进一步分裂光而获得的标准光的标准光路; 其中当施加所述标准光与所述参考光之间的干涉时的光路长度近似等于在施加所述参考光与所述反射光之间的干涉时的光路长度，并且包括用于计算相干光的时间变化的计算单元通过施加标准光和参考光之间的干扰获得的数据。

6. 发明授权

US08108032B2 Optical coherent tomography diagnostic apparatus 有权
标题翻译：光学相干断层扫描诊断仪
公开(公告)号：US08108032B2
公开(公告)日：2012-01-31
申请号：US12274991
申请日：2008-11-20
申请人： Yuuji Onimura , Adrien E. Desjardins
发明人： Yuuji Onimura , Adrien E. Desjardins
IPC分类号： A61B6/00
CPC分类号： A61B5/0073 , A61B5/0062 , A61B5/0066 , A61B5/0084
摘要： An optical coherent tomography diagnostic apparatus including: a light source; a splitter for splitting the light outputted from the light source into a measuring light and a reference light; a measuring light path; a reference light path; a probe inserted into a body cavity and emitting the measuring light to a subject of measurement; an image forming unit for calculating intensity distribution of the reflection light and for forming a tomographic image; a standard light path for transmitting standard light obtained by further splitting the light; wherein the light path length when exerting interference between the standard light and the reference light is approximately equal to the light path length when exerting interference between the reference light and the reflection light, and there is included a calculation unit for calculating time change of coherent light data obtained by exerting interference between the standard light and the reference light.
摘要翻译：一种光学相干断层摄影诊断装置，包括：光源; 分离器，用于将从光源输出的光分成测量光和参考光; 测光路; 参考光路; 插入体腔中并将测量光发射到测量对象的探针; 图像形成单元，用于计算反射光的强度分布和用于形成断层图像; 用于传送通过进一步分裂光而获得的标准光的标准光路; 其中当施加所述标准光与所述参考光之间的干涉时的光路长度近似等于在施加所述参考光与所述反射光之间的干涉时的光路长度，并且包括用于计算相干光的时间变化的计算单元通过施加标准光和参考光之间的干扰获得的数据。

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