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1. 发明申请

US20060229911A1 Personal control of healthcare information and related systems, methods, and devices 审中-公开
标题翻译：个人控制医疗信息及相关系统，方法和设备
公开(公告)号：US20060229911A1
公开(公告)日：2006-10-12
申请号：US11352704
申请日：2006-02-10
申请人： Adrian Gropper , William Donner , Sean Doyle , Yair Frankel
发明人： Adrian Gropper , William Donner , Sean Doyle , Yair Frankel
IPC分类号： G06Q10/00
CPC分类号： G06Q50/22 , G06F19/321 , G16H10/60
摘要： The invention, in one embodiment, is directed to a healthcare information system including: a client interface unit for creating one or more healthcare information documents, a repository in communication with the client interface unit for storing one or more healthcare information documents received from the client interface unit, a registry in communication with the repository for maintaining an index table of one or more healthcare information documents stored in the repository and for maintaining control information associated with each document for controlling the distribution of each documents from the repository, and a patient interface unit in communication with the registry for enabling a patient to configure at least a portion of the control information within the registry associated with one or more healthcare information documents.
摘要翻译：在一个实施例中，本发明涉及一种保健信息系统，包括：用于创建一个或多个保健信息文档的客户端接口单元，与客户接口单元通信的存储库，用于存储从客户接收的一个或多个保健信息文档接口单元，与所述存储库通信的注册表，用于维护存储在所述存储库中的一个或多个保健信息文档的索引表，并且用于维护与每个文档相关联的控制信息，以控制来自存储库的每个文档的分发;以及患者界面与注册单元通信的单元，用于使患者能够配置与一个或多个保健信息文档相关联的注册表内的控制信息的至少一部分。

2. 发明申请

US20070027715A1 Private health information interchange and related systems, methods, and devices 审中-公开
标题翻译：私人健康信息交换及相关系统，方法和设备
公开(公告)号：US20070027715A1
公开(公告)日：2007-02-01
申请号：US11451899
申请日：2006-06-13
申请人： Adrian Gropper , William Donner , Sean Doyle
发明人： Adrian Gropper , William Donner , Sean Doyle
IPC分类号： G06Q10/00
CPC分类号： G06Q10/10 , G06Q50/22 , G16H10/60
摘要： A healthcare information interchange system including a sender for originating one or more healthcare information documents associated with a patient, a first repository in communication with the sender for i) storing the one or more healthcare information documents received from the sender and ii) distributing the one or more healthcare information documents based on consent rules associated with each of the one or more documents, a recipient for receiving the one or more healthcare information documents based on the consent rules, and an identity provider for assigning first and second identities to the patient, the first identity being presented to the first repository by the sender to identify the patient, the second identity being presented by the first repository to the recipient to identify the patient.
摘要翻译：一种医疗保健信息交换系统，包括用于发起与患者相关联的一个或多个保健信息文件的发送者，与所述发送者通信的第一存储库，用于i）存储从所述发送者接收的所述一个或多个保健信息文档，以及ii）或基于与所述一个或多个文档中的每一个相关联的同意规则的更多保健信息文档，用于基于所述同意规则接收所述一个或多个保健信息文档的接收者以及用于向患者分配第一和第二身份的身份提供者，所述第一身份由所述发送者呈现给所述第一存储库以识别所述患者，所述第一身份由所述第一存储库呈现给所述接收者以识别所述患者。

3. 发明申请

US20070005798A1 System and method for virtual radiology and patient document flow 审中-公开
标题翻译：用于虚拟放射学和病人文件流的系统和方法
公开(公告)号：US20070005798A1
公开(公告)日：2007-01-04
申请号：US11089592
申请日：2004-05-17
申请人： Adrian Gropper , Sean Doyle , William Donner , Hugh Cottingham , Yair Frankel
发明人： Adrian Gropper , Sean Doyle , William Donner , Hugh Cottingham , Yair Frankel
IPC分类号： G06F15/173
CPC分类号： G06F19/321
摘要： The invention, in one embodiment, is directed to systems and methods for providing a “Virtual Radiology” service. This service, potentially, can provide any radiological digital image data to any computer at any institution. The service is “Virtual” in that the radiological digital image data accessible on a DICOM LAN and PACS of a first institution is made available to a second institution, without either institution having to open their networks to each other, establish legal or other business relationships and understandings or to become administratively involved with each other.
摘要翻译：在一个实施例中，本发明涉及用于提供“虚拟放射学”服务的系统和方法。该服务潜在地可以向任何机构的任何计算机提供任何放射性数字图像数据。该服务是“虚拟”，因为第一机构的DICOM LAN和PACS可访问的放射性数字图像数据可用于第二机构，而无需任何一个机构必须彼此打开网络，建立合法或其他业务关系理解或相互行政相关。

4. 发明申请

US20050237776A1 System and method for patient controlled communication of DICOM protected health information 审中-公开
标题翻译：用于DICOM保护的健康信息的患者控制通信的系统和方法
公开(公告)号：US20050237776A1
公开(公告)日：2005-10-27
申请号：US11089567
申请日：2004-03-19
申请人： Adrian Gropper , Sean Doyle , William Donner , Hugh Cottingham
发明人： Adrian Gropper , Sean Doyle , William Donner , Hugh Cottingham
IPC分类号： G06F17/00 , G06F17/50 , H05K1/02 , H05K1/11 , H05K3/00
CPC分类号： G06F17/5036 , H05K1/0237 , H05K1/115 , H05K3/0005 , H05K2201/09236
摘要： A method for verifying coupling in a differential via pair group includes identifying a differential via pair group in a design database and identifying a victim differential via pair in the differential via pair group. All other differential via pairs in the differential via pair group are identified as culprit differential pairs. The differential via pair group includes at least one culprit differential via pair. The method also includes obtaining a total coupling threshold level and calculating a total coupling factor for the victim differential via pair within the differential via pair group. The method also includes flagging the victim differential via pair if the calculated total coupling factor exceeds the total coupling threshold level.
摘要翻译：用于验证差分通路对组合中的耦合的方法包括在设计数据库中识别差分通路对组，并且通过差分通路对组中的对识别受害者差分。差分通孔对组中的所有其他差分通孔对被识别为凶手差分对。差分通路对组包括至少一个故障差分通路对。该方法还包括获得总耦合阈值电平并且计算差分通路对组内的受损差分通路对的总耦合因子。如果计算的总耦合系数超过总耦合阈值电平，该方法还包括通过对标记受害者差分。

5. 发明授权

US07756724B2 System and methods for real-time worklist service 有权
标题翻译：用于实时工作列表服务的系统和方法
公开(公告)号：US07756724B2
公开(公告)日：2010-07-13
申请号：US10301486
申请日：2002-11-21
申请人： Adrian Gropper , Sean Doyle , Terry Rosenbaum , Hamid Tabatabaie , Kang Wang
发明人： Adrian Gropper , Sean Doyle , Terry Rosenbaum , Hamid Tabatabaie , Kang Wang
IPC分类号： G06Q10/00 , G06Q50/00 , A61B5/00 , G06F19/00 , G06Q40/00
CPC分类号： G06Q10/02 , G06F19/00 , G06Q40/08 , G06Q50/22 , G06Q50/24 , G16H40/20
摘要： A system and methods for organizing, manipulating, and displaying worklists of patient studies for access by medical personnel is provided. The patient studies may include medical images and data relating to medical images. In some embodiments, the worklists are easily customizable, to permit a wide range of tasks to be handled in the worklist system. Updated worklist information may be pushed to the appropriate workstations or users in nearly real-time, as updates become available, reducing errors that may be caused by outdated information in worklists. In some embodiments, worklists contain overlapping information, which permits numerous users to see the information, even if it is not immediately relevant to their tasks. This increased scrutiny may help to reduce errors.
摘要翻译：提供了一种用于组织，操纵和显示患者研究工作列表以供医务人员进入的系统和方法。患者研究可以包括与医学图像相关的医学图像和数据。在一些实施例中，工作列表易于定制，以允许在工作列表系统中处理大范围的任务。更新的工作列表信息可能几乎实时地推送到相应的工作站或用户，因为更新可用，从而减少可能由工作列表中的过时信息引起的错误。在一些实施例中，工作列表包含重叠的信息，其允许许多用户查看信息，即使它们不直接与其任务相关。这种增加的审查可能有助于减少错误。

6. 发明授权

US07786075B2 Use of IL-28 and IL-29 to treat cancer and autoimmune disorders 有权
标题翻译：使用IL-28和IL-29治疗癌症和自身免疫性疾病
公开(公告)号：US07786075B2
公开(公告)日：2010-08-31
申请号：US12030107
申请日：2008-02-12
申请人： Sean Doyle , Kevin M. Klucher , Pallavur V. Sivakumar , Wayne R. Kindsvogel , Chung Chan
发明人： Sean Doyle , Kevin M. Klucher , Pallavur V. Sivakumar , Wayne R. Kindsvogel , Chung Chan
IPC分类号： A01N37/18
CPC分类号： A61K38/20 , A61K38/21 , A61K47/60 , C07K14/54 , C07K14/715 , C07K14/7155 , A61K2300/00
摘要： Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or IL-29 polypeptide sequence and proteins fused to a polypeptide with IL-28 and IL-29 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer and/or autoimmune therapeutics.
摘要翻译：使用IL-28和IL-29分子治疗患有癌症和自身免疫疾病的患者的方法。 IL-28和IL-29分子包括与人IL-28或IL-29多肽序列具有同源性的多肽，以及与具有IL-28和IL-29功能活性的多肽融合的蛋白质。分子可以用作单一疗法或与其它已知的癌症和/或自身免疫治疗剂组合使用。

7. 发明授权

US07747442B2 Speech recognition application grammar modeling 有权
标题翻译：语音识别应用语法建模
公开(公告)号：US07747442B2
公开(公告)日：2010-06-29
申请号：US11603673
申请日：2006-11-21
申请人： Sean Doyle
发明人： Sean Doyle
IPC分类号： G10L15/00 , G10L15/18 , G10L21/00
CPC分类号： G06F8/34 , G10L15/183 , G10L15/19
摘要： The subject mater herein relates to voice applications and, more particularly, speech recognition application grammar modeling. Various embodiments provide systems, methods, and software to present one or more user interfaces through which to receive input to define and manipulate properties of a graphical listen element, wherein the properties identify one or more data sources. Some such embodiments further include building a speech recognition program grammar as a function of one or more graphical listen elements, wherein the grammar includes a representation of data retrieved from the one or more data sources.
摘要翻译：本文的主题涉及语音应用，更具体地，涉及语音识别应用语法建模。各种实施例提供用于呈现一个或多个用户界面的系统，方法和软件，通过其接收输入以定义和操纵图形听单元的属性，其中该属性标识一个或多个数据源。一些这样的实施例还包括构建作为一个或多个图形听单元的函数的语音识别程序语法，其中所述语法包括从所述一个或多个数据源检索的数据的表示。

8. 发明申请

US20060057104A1 Methods for stimulating tlr irf3 pathways for inducing anti-microbial, anti-inflammatory and anticancer responses 审中-公开
标题翻译：刺激tlr irf3途径诱导抗微生物，抗炎和抗癌反应的方法
公开(公告)号：US20060057104A1
公开(公告)日：2006-03-16
申请号：US10512124
申请日：2003-04-24
申请人： Genhong Cheng , Robert Modlin , Sagar Vaidya , Sean Doyle
发明人： Genhong Cheng , Robert Modlin , Sagar Vaidya , Sean Doyle
IPC分类号： A61K48/00 , A61K38/21 , A61K39/00 , A61K31/739 , A61K31/4745 , A61K31/337
CPC分类号： A61K31/337 , A61K31/4745 , A61K31/739 , A61K38/162 , A61K39/00 , A61K39/39 , A61K2039/55511 , A61K2039/55516 , A61K2039/55561 , A61K2039/55572 , A61K2039/55594 , C12Q1/18 , G01N33/6866 , G01N33/6872 , G01N2333/565
摘要： The present invention provides methods for stimulating Toll-like receptors (TLR) to activate IRF (e.g., an IRF3) and signaling pathway, and thereby directing an antimicrobial activity. The present invention also provides methods for identifying agents that bind and/or stimulate TLR and mediate induction of an IRF3 pathway, thereby directing an antimicrobial activity. Additionally, the invention provides methods and agents for suppressing stimulation of TLR, thereby directing an anti-inflammatory response.
摘要翻译：本发明提供刺激Toll样受体（TLR）激活IRF（例如IRF3）和信号传导途径，从而引导抗微生物活性的方法。本发明还提供了用于鉴定结合和/或刺激TLR并介导IRF3途径的诱导从而引导抗微生物活性的试剂的方法。此外，本发明提供抑制TLR刺激的方法和试剂，从而引发抗炎反应。

9. 发明申请

US20100291030A1 USE OF IL-28 AND IL-29 TO TREAT CANCER AND AUTOIMMUNE DISORDERS 有权
标题翻译：使用IL-28和IL-29治疗癌症和自身免疫性疾病
公开(公告)号：US20100291030A1
公开(公告)日：2010-11-18
申请号：US12818050
申请日：2010-06-17
申请人： Sean Doyle , Kevin M. Klucher , Pallavur V. Sivakumar , Wayne R. Kindsvogel , Chung Chan
发明人： Sean Doyle , Kevin M. Klucher , Pallavur V. Sivakumar , Wayne R. Kindsvogel , Chung Chan
IPC分类号： A61K38/20 , A61P35/00 , A61P37/00
CPC分类号： A61K38/20 , A61K38/21 , A61K47/60 , C07K14/54 , C07K14/715 , C07K14/7155 , A61K2300/00
摘要： Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or IL-29 polypeptide sequence and proteins fused to a polypeptide with IL-28 and IL-29 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer and/or autoimmune therapeutics.
摘要翻译：使用IL-28和IL-29分子治疗患有癌症和自身免疫疾病的患者的方法。 IL-28和IL-29分子包括与人IL-28或IL-29多肽序列具有同源性的多肽，以及与具有IL-28和IL-29功能活性的多肽融合的蛋白质。分子可以用作单一疗法或与其它已知的癌症和/或自身免疫治疗剂组合使用。

10. 发明申请

US20080167244A1 USE OF IL-28 AND IL-29 TO TREAT CANCER AND AUTOIMMUNE DISORDERS 有权
标题翻译：使用IL-28和IL-29治疗癌症和自身免疫性疾病
公开(公告)号：US20080167244A1
公开(公告)日：2008-07-10
申请号：US12030107
申请日：2008-02-12
申请人： Sean Doyle , Kevin M. Klucher , Pallavur V. Sivakumar , Wayne R. Kindsvogel , Chung Chan
发明人： Sean Doyle , Kevin M. Klucher , Pallavur V. Sivakumar , Wayne R. Kindsvogel , Chung Chan
IPC分类号： A61K38/16 , A61P35/04
CPC分类号： A61K38/20 , A61K38/21 , A61K47/60 , C07K14/54 , C07K14/715 , C07K14/7155 , A61K2300/00
摘要： Methods for treating patients with cancer and autoimmune disorders using IL-28 and IL-29 molecules. The IL-28 and IL-29 molecules include polypeptides that have homology to the human IL-28 or IL-29 polypeptide sequence and proteins fused to a polypeptide with IL-28 and IL-29 functional activity. The molecules can be used as a monotherapy or in combination with other known cancer and/or autoimmune therapeutics.
摘要翻译：使用IL-28和IL-29分子治疗患有癌症和自身免疫疾病的患者的方法。 IL-28和IL-29分子包括与人IL-28或IL-29多肽序列具有同源性的多肽，以及与具有IL-28和IL-29功能活性的多肽融合的蛋白质。分子可以用作单一疗法或与其它已知的癌症和/或自身免疫治疗剂组合使用。

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