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1. 发明授权

US08052926B2 Method for manufacturing a sterilized lancet integrated biosensor 失效
标题翻译：无菌柳叶刀综合生物传感器的制造方法
公开(公告)号：US08052926B2
公开(公告)日：2011-11-08
申请号：US12180101
申请日：2008-07-25
申请人： Abner David Joseph , Frank A. Chan , Steven N. Roe
发明人： Abner David Joseph , Frank A. Chan , Steven N. Roe
IPC分类号： A61L2/00 , H01J27/00 , G01N23/00 , A61N5/00 , A61B10/00 , A61B5/00 , B65B55/02 , B65B9/00 , B65B51/10
CPC分类号： B65B55/16 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150061 , A61B5/150213 , A61B5/150282 , A61B5/15032 , A61B5/150328 , A61B5/150335 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/157 , A61B2562/0295 , A61L2/087 , A61L2202/181 , A61L2202/24
摘要： An integrated disposable includes a test strip and a lancet packet coupled to the test strip. The lancet packet includes a sterility sheet enclosing at least a portion of a lancet to maintain the sterility of the lancet. The lancet packet and the sterility sheet, in particular, allow the lancet to be sterilized separately from the test strip. The lancet in one form is incorporated into a lancet tape that is sterilized in a continuous, reel-to-reel sterilization process. The lancet tape in one form is sterilized using an electron beam sterilization process. With electron beam sterilization, sterilization is enhanced by irradiating both sides of the tape with electron beams. Sterilization can adversely affect chemical reagents in the test strip. To alleviate this chemistry degradation issue, the lancet packet is attached to the test strip after the lancet is sterilized.
摘要翻译：一体化一次性包括测试条和联接到测试条的刺血针包。柳叶刀包包括包围刺血针的至少一部分以维持刺血针的不育性的无菌片。特别是柳叶刀包和无菌片允许刺血针与测试条分开灭菌。一种形式的刺血针被并入刺血针带中，其在连续的卷轴对卷筒灭菌过程中被灭菌。一种形式的刺血针胶带使用电子束灭菌方法进行灭菌。通过电子束灭菌，通过用电子束照射带的两侧来增强灭菌。灭菌可能对测试条中的化学试剂产生不利影响。为了减轻这种化学降解问题，在刺血针灭菌后将刺血针包装在试纸上。

2. 发明申请

US20090010802A1 METHOD FOR MANUFACTURING A STERILIZED LANCET INTEGRATED BIOSENSOR 失效
标题翻译：一种灭菌的LANCET集成生物传感器的制造方法
公开(公告)号：US20090010802A1
公开(公告)日：2009-01-08
申请号：US12180101
申请日：2008-07-25
申请人： Abner David Joseph , Frank A. Chan , Steven N. Roe
发明人： Abner David Joseph , Frank A. Chan , Steven N. Roe
IPC分类号： A61L2/03 , A61L2/00
CPC分类号： B65B55/16 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150061 , A61B5/150213 , A61B5/150282 , A61B5/15032 , A61B5/150328 , A61B5/150335 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/157 , A61B2562/0295 , A61L2/087 , A61L2202/181 , A61L2202/24
摘要： An integrated disposable includes a test strip and a lancet packet coupled to the test strip. The lancet packet includes a sterility sheet enclosing at least a portion of a lancet to maintain the sterility of the lancet. The lancet packet and the sterility sheet, in particular, allow the lancet to be sterilized separately from the test strip. The lancet in one form is incorporated into a lancet tape that is sterilized in a continuous, reel-to-reel sterilization process. The lancet tape in one form is sterilized using an electron beam sterilization process. With electron beam sterilization, sterilization is enhanced by irradiating both sides of the tape with electron beams. Sterilization can adversely affect chemical reagents in the test strip. To alleviate this chemistry degradation issue, the lancet packet is attached to the test strip after the lancet is sterilized.
摘要翻译：一体化一次性包括测试条和联接到测试条的刺血针包。柳叶刀包包括包围刺血针的至少一部分以维持刺血针的不育性的无菌片。特别是柳叶刀包和无菌片允许刺血针与测试条分开灭菌。一种形式的刺血针被并入刺血针带中，其在连续的卷轴对卷筒灭菌过程中被灭菌。一种形式的刺血针胶带使用电子束灭菌方法进行灭菌。通过电子束灭菌，通过用电子束照射带的两侧来增强灭菌。灭菌可能对测试条中的化学试剂产生不利影响。为了减轻这种化学降解问题，在刺血针灭菌后将刺血针包装在试纸上。

3. 发明授权

US09332938B2 Flat lancet immobilization 有权
标题翻译：扁平刺血针固定
公开(公告)号：US09332938B2
公开(公告)日：2016-05-10
申请号：US12208698
申请日：2008-09-11
申请人： Frank A. Chan , Daniel Wong , Charles C. Raney , Christopher Wiegel , Steven N. Roe
发明人： Frank A. Chan , Daniel Wong , Charles C. Raney , Christopher Wiegel , Steven N. Roe
IPC分类号： A61B5/157 , A61B5/15 , A61B5/145 , A61B5/1468 , A61B5/151 , A61B17/3209 , A61B10/00
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/1468 , A61B5/150022 , A61B5/150213 , A61B5/150282 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150809 , A61B5/150816 , A61B5/150916 , A61B5/15142 , A61B5/1519 , A61B17/32093 , A61B2010/0003 , A61B2562/0295
摘要： A lancet enclosed in a sterility sheet forms a lancet packet to maintain the sterility of the lancet and prevent the lancet from unintentionally piercing the sterility sheet prior to lancet actuation. In one form, the lancet is immobilized by hot tack welding a portion of the sterility sheet to the lancet. Alternatively, portions of the sterility sheet are hot tack welded together through an opening in the lancet to limit movement of the lancet.
摘要翻译：包围在无菌片中的柳叶刀形成柳叶刀包，以维持刺血针的不整洁性，并防止刺血针在刺血针致动之前无意中刺穿无菌片。在一种形式中，通过将无菌片的一部分热定位焊接到刺血针来固定刺血针。或者，通过刺血针中的开口将无菌片的部分热定位焊接在一起，以限制刺血针的运动。

4. 发明申请

US20090036797A1 FLAT LANCET IMMOBILIZATION 有权
标题翻译：平面网络化
公开(公告)号：US20090036797A1
公开(公告)日：2009-02-05
申请号：US12208698
申请日：2008-09-11
申请人： Frank A. Chan , Daniel Wong , Charles C. Raney , Christopher Wiegel , Steven N. Roe
发明人： Frank A. Chan , Daniel Wong , Charles C. Raney , Christopher Wiegel , Steven N. Roe
IPC分类号： A61B5/151 , B65B51/24 , B67B7/00
CPC分类号： A61B5/157 , A61B5/1411 , A61B5/14532 , A61B5/1468 , A61B5/150022 , A61B5/150213 , A61B5/150282 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150809 , A61B5/150816 , A61B5/150916 , A61B5/15142 , A61B5/1519 , A61B17/32093 , A61B2010/0003 , A61B2562/0295
摘要： A lancet enclosed in a sterility sheet forms a lancet packet to maintain the sterility of the lancet and prevent the lancet from unintentionally piercing the sterility sheet prior to lancet actuation. In one form, the lancet is immobilized by hot tack welding a portion of the sterility sheet to the lancet. Alternatively, portions of the sterility sheet are hot tack welded together through an opening in the lancet to limit movement of the lancet.
摘要翻译：包围在无菌片中的柳叶刀形成柳叶刀包，以维持刺血针的不整洁性，并防止刺血针在刺血针致动之前无意中刺穿无菌片。在一种形式中，通过将无菌片的一部分热定位焊接到刺血针来固定刺血针。或者，通过刺血针中的开口将无菌片的部分热定位焊接在一起，以限制刺血针的运动。

5. 发明申请

US20120172757A1 Handheld Medical Diagnostic Devices Housing Lancet Structures 审中-公开
标题翻译：手持式医疗诊断设备住房柳叶刀结构
公开(公告)号：US20120172757A1
公开(公告)日：2012-07-05
申请号：US12981696
申请日：2010-12-30
申请人： Steven N. Roe
发明人： Steven N. Roe
IPC分类号： A61B5/151
CPC分类号： A61B5/15182 , A61B5/150022 , A61B5/150175 , A61B5/15019 , A61B5/150259 , A61B5/150267 , A61B5/150358 , A61B5/150435 , A61B5/15045 , A61B5/150458 , A61B5/150465 , A61B5/150511 , A61B5/150572 , A61B5/150916 , A61B5/150946 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/15132 , A61B5/15146 , A61B5/15151 , A61B5/15161 , A61B5/157
摘要： A lancet housing assembly includes multiple lancets for use in a portable handheld medical diagnostic device for sampling bodily fluids from a skin site of a patient. The lancet housing assembly includes a housing structure comprising multiple lancet compartments. At least one of the lancet compartments includes an outer facing side and an inner facing side. An opening is located at the outer facing side that is arranged and configured to align with a lancet port of the medical diagnostic device. A lancet structure is located in the at least one lancet compartment and comprises a skin penetrating end and a blood transport portion adjacent the skin penetrating end. The lancet structure has (i) an initial configuration where the lancet structure is supported to align the skin penetrating end with the opening to allow the skin penetrating end to extend through the opening and (ii) a retracted configuration where the skin penetrating end moves to a position within the lancet compartment offset from the opening to prevent the lancet structure from extending through the opening.
摘要翻译：柳叶刀壳体组件包括用于便携式手持式医疗诊断装置中用于从患者皮肤部位取样体液的多个刺血针。柳叶刀壳体组件包括包括多个刺血针室的壳体结构。柳叶刀舱中的至少一个包括外侧和内侧。开口位于面向外侧的位置，该开口被布置和构造成与医疗诊断装置的刺血针端口对准。柳叶刀结构位于所述至少一个刺血针室中，并且包括皮肤穿透端和与皮肤穿透端相邻的血液输送部。柳叶刀结构具有（i）支撑柳叶刀结构以将皮肤穿透端与开口对准以使皮肤穿透端延伸穿过开口的初始构型，以及（ii）皮肤穿透端移动到刺血针室内的位置偏离开口以防止刺血针结构延伸穿过开口。

6. 发明申请

US20120172756A1 Handheld Medical Diagnostic Devices 审中-公开
标题翻译：手持式医疗诊断设备
公开(公告)号：US20120172756A1
公开(公告)日：2012-07-05
申请号：US12981677
申请日：2010-12-30
申请人： Steven N. Roe , Chris Fruhauf , Max Chen
发明人： Steven N. Roe , Chris Fruhauf , Max Chen
IPC分类号： A61B5/151
CPC分类号： A61B5/15182 , A61B5/150022 , A61B5/150175 , A61B5/15019 , A61B5/150259 , A61B5/150267 , A61B5/150358 , A61B5/150435 , A61B5/15045 , A61B5/150458 , A61B5/150465 , A61B5/150511 , A61B5/150572 , A61B5/150916 , A61B5/150946 , A61B5/15113 , A61B5/15117 , A61B5/1513 , A61B5/15132 , A61B5/15146 , A61B5/15151 , A61B5/15161 , A61B5/157
摘要： A method of driving a lancet structure in a portable handheld medical diagnostic device is provided. The method includes connecting a spring-driven motor to the lancet structure within a housing structure of the portable handheld medical diagnostic device. The spring-driven motor is wound to a cocked, triggerable configuration. The spring-driven motor is triggered such that, when triggered, the spring-driven motor (i) displaces a skin penetrating end of the lancet structure outwardly from the housing structure through a lancet port and (ii) retracts the skin penetrating end of the lancet structure back into the housing structure.
摘要翻译：提供了一种在便携式手持医疗诊断装置中驱动刺血针结构的方法。该方法包括将弹簧驱动的马达连接到便携式手持式医疗诊断装置的壳体结构内的刺血针结构。弹簧驱动的电机被卷绕成一个翘起的，可触发的配置。触发弹簧驱动的电动机，使得当被触发时，弹簧驱动的电动机（i）通过刺血针端口将刺血针结构的皮肤穿透端部从壳体结构向外移动，并且（ii）使皮肤穿透端部柳叶刀结构回到房屋结构。

7. 发明申请

US20120065545A1 SAMPLING DEVICES AND METHODS UTILIZING BIASED CAPILLARY ACTION 审中-公开
标题翻译：采样设备和使用偏心毛细管动作的方法
公开(公告)号：US20120065545A1
公开(公告)日：2012-03-15
申请号：US13304441
申请日：2011-11-25
申请人： Steven N. Roe
发明人： Steven N. Roe
IPC分类号： A61B5/00
CPC分类号： A61B5/150358 , A61B5/150022
摘要： A device is constructed so as to define a capillary channel that draws a body fluid form a proximal portion of the capillary channel toward a distal portion. A counterbore defining a “ledge” not substantially normal to the center line of channel causes the meniscus of body fluid to be “biased” into a non-radially-symmetric shape. In one example, the bias draws the body fluid toward a testing element that is set into a groove in the main body of the device. In another example, hydrophilic and/or hydrophobic regions are created on or in device to produce the biasing effect. In certain configurations, device requires less blood to be drawn into the capillary channel for a successful test than if the biasing effect were not created.
摘要翻译：一种装置被构造成限定毛细管通道，该毛细通道从毛细管通道的近端部分朝向远端部分抽取体液。限定基本上不垂直于通道的中心线的“凸缘”的沉孔引起体液的弯液面被“偏压”成非径向对称的形状。在一个示例中，偏压将体液朝向设置在装置的主体中的凹槽中的测试元件拉出。在另一个实例中，在设备上或设备中产生亲水和/或疏水区域以产生偏置效应。在某些配置中，与没有产生偏置效应相比，设备需要较少的血液被吸入毛细通道才能成功测试。

8. 发明授权

US08118824B2 Magnetic powered lancing drive 失效
标题翻译：磁力牵引驱动
公开(公告)号：US08118824B2
公开(公告)日：2012-02-21
申请号：US12211408
申请日：2008-09-16
申请人： Steven N. Roe
发明人： Steven N. Roe
IPC分类号： A61B17/32
CPC分类号： A61B5/15194 , A61B5/150022 , A61B5/150167 , A61B5/150183 , A61B5/150412 , A61B5/150503 , A61B5/15113 , A61B5/15123 , A61B5/1519
摘要： A self-powered lancing drive system and lancing technique uses permanent magnets to initially store the potential energy that is converted to kinetic energy for extending a lancet during lancing. This self-powered lancing drive system is a pure permanent magnet drive that is highly reliable under numerous operating conditions. Permanent magnets can produce stronger magnetic fields at smaller sizes as compared to electromagnets. In one form, the lancing system has a drive permanent magnet that is kept fixed or stationary while the lancet magnet travels along the firing path. With the drive magnet being stationary, the lancet experiences fewer fluctuations in the magnetic field. The lancet vibrates less and is driven straighter into the tissue. In another form, a retraction magnet is positioned at the end of the firing path of the lancet, near the tissue, to enhance retraction of the lancet. In another form, a mechanical structure keeps the magnets in close proximity so that the strength of the magnetic propulsion force is maintained. The mechanical structure in one example is a crank mechanism that confines magnet movement to a circular path. The crank mechanism provides a smooth lancing profile as well as facilitates adjustments to the lancing profile.
摘要翻译：自动牵引驱动系统和穿刺技术使用永久磁铁来初始储存转换为动能的势能，以便在穿刺期间延长刺血针。这种自供电的牵引驱动系统是一种纯永磁驱动器，在许多操作条件下都是高度可靠的。与电磁铁相比，永磁体可以以较小的尺寸产生更强的磁场。在一种形式中，穿刺系统具有驱动永磁体，其在柳叶刀磁体沿着击发路径行进时保持固定或静止。在驱动磁体静止的情况下，刺血针的磁场波动较少。柳叶刀振动较小，并且更直接地驱动到组织中。在另一种形式中，收缩磁体位于柳叶刀的靠近组织的射击路径的末端，以增强刺血针的收缩。在另一种形式中，机械结构保持磁体紧密接近，从而保持磁推进力的强度。一个示例中的机械结构是将磁体运动限制到圆形路径的曲柄机构。曲柄机构提供平滑的穿刺剖面，并且便于对穿刺剖面进行调整。

9. 发明申请

US20110237979A1 PRECISION DEPTH CONTROL LANCING TIP 有权
标题翻译：精密深度控制系统
公开(公告)号：US20110237979A1
公开(公告)日：2011-09-29
申请号：US13154497
申请日：2011-06-07
申请人： Steven N. Roe , Chris Wiegel
发明人： Steven N. Roe , Chris Wiegel
IPC分类号： A61B5/151
CPC分类号： A61B5/150717 , A61B5/150022 , A61B5/150068 , A61B5/15019 , A61B5/150358 , A61B5/150412 , A61B5/150442 , A61B5/150503 , A61B5/150549 , A61B5/150618 , A61B5/1519 , A61B5/15194
摘要： A bodily fluid sampling device is operable to lance with a precise depth and express fluid from both fingertip and alternate sites. In one form, the device is operable to adjust the penetration depth of the lancet into the skin. The bodily fluid sampling device includes a lancet adapted to form an incision in skin. A skin contacting member has an orifice through which the lancet extends when lancing the skin. The orifice has a first opening size that is sized to flatten the skin around the lancet during lancing. The orifice has a second opening size that is larger than the first opening size after the incision is formed to express fluid from the incision.
摘要翻译：体液采样装置可操作以用精确的深度喷枪并从指尖和替代部位表达流体。在一种形式中，该装置可操作以调节刺血针进入皮肤的穿透深度。体液取样装置包括适于在皮肤中形成切口的刺血针。皮肤接触构件具有孔，当穿刺皮肤时柳叶刀延伸穿过该孔。孔口具有第一开口尺寸，其尺寸适于在穿刺期间使柳叶刀周围的皮肤变平。在形成切口以从切口表达流体之后，孔口具有大于第一开口尺寸的第二开口尺寸。

10. 发明授权

US08016775B2 Dual blade lancing test strip 有权
标题翻译：双刀片测试条
公开(公告)号：US08016775B2
公开(公告)日：2011-09-13
申请号：US12581477
申请日：2009-10-19
申请人： Steven N. Roe , Jeffrey N. Roe
发明人： Steven N. Roe , Jeffrey N. Roe
IPC分类号： A61B5/00 , B65D81/00
CPC分类号： A61B5/14532 , A61B5/150022 , A61B5/150213 , A61B5/150358 , A61B5/150442 , A61B5/150503 , A61B5/15142
摘要： An integrated lancing test strip includes a pair of blade members that each have a lancing tip that are configured to lance skin. A pair of spacer members connect the blade members together such that the blade members define an internal capillary. A test strip is positioned along the internal capillary, and the test strip is configured to test analyte levels in the bodily fluid. During use, the lancing tips form one or more incisions in the skin. The fluid from the incisions is drawn via capillary action through the internal capillary and onto the test strip.
摘要翻译：集成的穿刺测试条包括一对刀片构件，每个刀片构件具有构造成刺穿皮肤的穿刺尖端。一对间隔件将叶片构件连接在一起，使得叶片构件限定内部毛细管。测试条沿着内部毛细管定位，并且测试条被配置成测试体液中的分析物水平。在使用过程中，穿刺尖端在皮肤中形成一个或多个切口。来自切口的流体通过毛细管作用通过内部毛细管并被拉到测试条上。

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