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1. 发明授权

US5273741A Packaged anti-plaque oral compositions 失效
标题翻译：包装的抗斑块口服组合物
公开(公告)号：US5273741A
公开(公告)日：1993-12-28
申请号：US922252
申请日：1992-07-30
申请人： Abdul Gaftar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
发明人： Abdul Gaftar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
IPC分类号： A61K8/34 , A61Q11/00 , A61K7/16 , A61K7/18 , A61K7/26
CPC分类号： A61Q11/00 , A61K8/347 , A61K2800/87 , Y10S514/90 , Y10S514/901 , Y10S514/902
摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container or bottle which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. Also described is a method for inhibiting development of plaque on teeth.
摘要翻译：包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少牙齿包装在分配容器或瓶子中，该分配容器或瓶子包括与抗菌剂相容的诸如聚氟乙烯的固体聚合物材料，从而避免了这种药剂在储存时过度的抗斑块活性损失。或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用通过稳定剂如萜烯的存在来抵消，例如苎烯，在口服组合物配方中。还描述了抑制牙齿斑块发展的方法。

2. 发明授权

US5496540A Plaque inhibition with antiplaque oral composition dispensed from container having polymeric material in contact and compatible with the composition 失效
标题翻译：从具有接触并与组合物相容的聚合材料的容器分配的抗斑块口服组合物的斑块抑制
公开(公告)号：US5496540A
公开(公告)日：1996-03-05
申请号：US179272
申请日：1994-01-10
申请人： Abdul Gaffar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
发明人： Abdul Gaffar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
IPC分类号： A61K8/04 , A61K8/24 , A61K8/34 , A61Q11/00 , A61K7/16 , A61K7/18
CPC分类号： A61K8/046 , A61K8/24 , A61K8/347 , A61Q11/00 , Y10S514/90 , Y10S514/901 , Y10S514/902
摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. The oral composition preferably contains a tooth hardening proportion of a source of fluoride ions, an anti-tartar proportion of a polyphosphate, a stabilizing proportion (in conjunction with the fluoride source) for the polyphosphate, of a polyvinyl methyl ether-maleic anhydride copolymer, and normal adjuvants for the oral preparation. A method for inhibiting development of plaque on teeth is also within the invention, as is a cleaning article containing an effective amount of the invented dentifrice.
摘要翻译：包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少牙齿被包装在分配容器中，该分配容器包括与抗菌剂相容的固体聚合物材料，例如聚氟乙烯，从而避免了这种药剂在储存时过度的抗斑块活性损失。或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用由稳定剂如萜烯的存在来抵消，例如，柠檬烯，口服组合物配方。口服组合物优选含有聚乙烯基醚 - 马来酸酐共聚物的氟化物离子源，多磷酸盐的抗牙垢比例，多磷酸盐的稳定化比例（与氟化物源结合）的牙齿硬化比例，和用于口服制剂的正常佐剂。抑制牙齿斑块发展的方法也在本发明的范围内，含有有效量的本发明洁牙剂的清洁用品也是如此。

3. 发明授权

US5167951A Article comprising a dispensing container that includes solid polymeric material in contact with an antiplaque oral composition with which it is compatible 失效
标题翻译：一种包含分配容器的制品，其包括与可与其兼容的抗牙釉质口服组合物接触的固体聚合物材料
公开(公告)号：US5167951A
公开(公告)日：1992-12-01
申请号：US505628
申请日：1990-04-06
申请人： Abdul Gaffar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
发明人： Abdul Gaffar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
IPC分类号： A61K8/34 , A61K8/81 , A61Q11/00
CPC分类号： A61K8/347 , A61K8/81 , A61K8/8164 , A61Q11/00 , A61K2800/87 , Y10S514/90 , Y10S514/901
摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition, but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. The oral composition preferably contains a tooth hardening proportion of a source of fluoride ions, an anti-tartar proportion of a polyphosphate, a stabilizing proportion (in conjunction with the fluoride source) for the polyphosphate, of a polyvinyl methyl ether-maleic anhydride copolymer, and normal adjuvants for the oral preparation. A method for inhibiting development of plaque on teeth is also within the invention, as is a cleaning article containing an effective amount of the invented dentifrice.
摘要翻译：包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少牙齿被包装在分配容器中，该分配容器包括与抗菌剂相容的固体聚合物材料，例如聚氟乙烯，从而避免了这种药剂在储存时过度的抗斑块活性损失。或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用由稳定剂如萜烯的存在来抵消，例如，柠檬烯，口服组合物配方。口服组合物优选含有聚乙烯基醚 - 马来酸酐共聚物的氟化物离子源，多磷酸盐的抗牙垢比例，多磷酸盐的稳定化比例（与氟化物源结合）的牙齿硬化比例，和用于口服制剂的正常佐剂。抑制牙齿斑块发展的方法也在本发明的范围内，含有有效量的本发明洁牙剂的清洁用品也是如此。

4. 发明授权

US5279813A Plaque inhibition with antiplaque oral composition dispensed from container having polymeric material in contact and compatible with the composition 失效
标题翻译：从具有接触并与组合物相容的聚合材料的容器分配的抗斑块口服组合物的斑块抑制
公开(公告)号：US5279813A
公开(公告)日：1994-01-18
申请号：US931622
申请日：1992-08-18
申请人： Abdul Gaffar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
发明人： Abdul Gaffar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
IPC分类号： A61K8/04 , A61K8/24 , A61K8/34 , A61Q11/00 , A61K7/16
CPC分类号： A61K8/046 , A61K8/24 , A61K8/347 , A61Q11/00 , Y10S514/90 , Y10S514/901 , Y10S514/902
摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque activity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. The oral composition preferably contains a tooth hardening proportion of a source of fluoride ions, an anti-tartar proportion of a polyphosphate, a stabilizing proportion (in conjunction with the fluoride source) for the polyphosphate, of a polyvinyl methyl ether-maleic anhydride copolymer, and normal adjuvants for the oral preparation. A method for inhibiting development of plaque on teeth is also within the invention, as is a cleaning article containing an effective amount of the invented dentifrice.
摘要翻译：包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少牙齿被包装在分配容器中，该分配容器包括与抗菌剂相容的固体聚合物材料，例如聚氟乙烯，从而避免了这种药剂在储存时过度的抗斑块活性损失。或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用通过稳定剂如萜烯的存在来抵消，例如苎烯，在口服组合物配方中。口服组合物优选含有聚乙烯基醚 - 马来酸酐共聚物的氟化物离子源，多磷酸盐的抗牙垢比例，多磷酸盐的稳定化比例（与氟化物源结合）的牙齿硬化比例，和用于口服制剂的正常佐剂。抑制牙齿斑块发展的方法也在本发明的范围内，含有有效量的本发明洁牙剂的清洁用品也是如此。

5. 发明授权

US5135738A Article comprising a dispensing container of polymeric material in contact with an antiplaque oral composition with which it is compatible 失效
标题翻译：包含聚合物质分配容器的文章与其兼容的ANTIPLAQUE口味组合物接触
公开(公告)号：US5135738A
公开(公告)日：1992-08-04
申请号：US427660
申请日：1989-10-26
申请人： Abdul Gaffar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
发明人： Abdul Gaffar , Richard S. Robinson , Jeffrey Miller , Chimpiramma Potini , Michael A. Collins , Theresa G. Shackil
IPC分类号： A61K8/34 , A61K8/81 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/347 , A61K8/8164 , A61K2800/87 , Y10S514/90 , Y10S514/901 , Y10S514/902
摘要： An oral composition, such as a paste or gel dentifrice or a liquid mouthwash, containing a substantially water insoluble non-cationic antibacterial agent, such as triclosan, which, when used to clean the teeth or rinse the mouth, acts to decrease plaque on the teeth, is packaged in a dispensing container or bottle which includes a solid polymeric material, such as polyfluoroethylene, which is compatible with the antibacterial agent so that excessive loss of anti-plaque acitivity of such agent on storage is avoided. Alternatively, various other polymers may be employed as container parts, which normally would cause excessive losses of anti-plaque action of the antibacterial agent in the composition but such action is countered by the presence of a stabilizer, such as a terpene, e.g., limonene, in the oral composition formula. Also described is a method for inhibiting development of plaque on teeth.
摘要翻译：包含基本上不溶于水的非阳离子抗菌剂（例如三氯生）的口服组合物，例如糊剂或凝胶洁齿剂或液体漱口剂，其用于清洁牙齿或冲洗口腔时起作用以减少牙齿被包装在分配容器或瓶子中，该分配容器或瓶子包括与抗菌剂相容的固体聚合材料，例如聚氟乙烯，从而避免了这种药剂在储存时过量的抗斑块活性丧失。或者，可以使用各种其它聚合物作为容器部件，其通常将导致组合物中抗菌剂的抗斑块作用的过度损失，但是这种作用通过稳定剂如萜烯的存在来抵消，例如苎烯，在口服组合物配方中。还描述了抑制牙齿斑块发展的方法。

6. 发明授权

US5607908A Composition for cleaning contact lenses 失效
标题翻译：用于清洁隐形眼镜的组合物
公开(公告)号：US5607908A
公开(公告)日：1997-03-04
申请号：US407519
申请日：1995-03-16
申请人： Chimpiramma Potini , Stanley J. Wrobel
发明人： Chimpiramma Potini , Stanley J. Wrobel
IPC分类号： C11D3/00 , C11D3/37 , C11D1/82 , C11D3/48
CPC分类号： C11D3/3738 , C11D3/0078
摘要： A composition for cleaning contact lenses comprises a silicone surface active agent having cleaning activity for contact lens deposits. The silicone surface active agent has at least one side chain including a radical ionizable in aqueous solution.
摘要翻译：用于清洁隐形眼镜的组合物包括对隐形眼镜沉积物具有清洁活性的硅氧烷表面活性剂。硅氧烷表面活性剂具有至少一个侧链，其包括可在水溶液中电离的自由基。

7. 发明授权

US5422029A Composition for cleaning contact lenses 失效
标题翻译：用于清洁隐形眼镜的组合物
公开(公告)号：US5422029A
公开(公告)日：1995-06-06
申请号：US080424
申请日：1993-06-18
申请人： Chimpiramma Potini , Stanley J. Wrobel
发明人： Chimpiramma Potini , Stanley J. Wrobel
IPC分类号： C11D3/00 , C11D3/37 , C11D3/48
CPC分类号： C11D3/3738 , C11D3/0078
摘要： A composition for cleaning contact lenses comprises a silicone surface active agent having cleaning activity for contact lens deposits. The silicone surface active agent has at least one side chain including a radical ionizable in aqueous solution.
摘要翻译：用于清洁隐形眼镜的组合物包括对隐形眼镜沉积物具有清洁活性的硅氧烷表面活性剂。硅氧烷表面活性剂具有至少一个侧链，其包括可在水溶液中电离的自由基。

8. 发明授权

US5604189A Composition for cleaning and wetting contact lenses 失效
标题翻译：用于清洁和润湿隐形眼镜的组合物
公开(公告)号：US5604189A
公开(公告)日：1997-02-18
申请号：US468603
申请日：1995-06-06
申请人： Hong J. Zhang , Edward J. Ellis , Stanley J. Wrobel , Chimpiramma Potini
发明人： Hong J. Zhang , Edward J. Ellis , Stanley J. Wrobel , Chimpiramma Potini
IPC分类号： G02C13/00 , C11D1/00 , C11D1/66 , C11D1/72 , C11D1/722 , C11D1/82 , C11D3/00 , C11D3/22 , C11D3/37 , C11D3/48
CPC分类号： C11D3/3738 , C11D1/008 , C11D1/662 , C11D1/72 , C11D1/82 , C11D3/0078 , C11D3/225 , C11D3/3707 , C11D3/373 , C11D3/3753 , C11D3/3776 , C11D1/722 , Y10S514/839
摘要： A composition for cleaning and wetting contact lenses comprises a polyethyleneoxide-containing material having a hydrophile-lipophile balance (HLB) of at least about 18, a surface active agent having cleaning activity for contact lens deposits, and a wetting agent.
摘要翻译：用于清洁和润湿隐形眼镜的组合物包括具有至少约18的亲水 - 亲油平衡（HLB）的聚环氧乙烷的材料，具有用于隐形眼镜沉积物的清洁活性的表面活性剂和润湿剂。

9. 发明授权

US5500144A Composition for cleaning and wetting contact lenses 失效
标题翻译：用于清洁和润湿隐形眼镜的组合物
公开(公告)号：US5500144A
公开(公告)日：1996-03-19
申请号：US420915
申请日：1995-04-12
申请人： Chimpiramma Potini , Stanley J. Wrobel , Hong J. Zhang , Edward J. Ellis
发明人： Chimpiramma Potini , Stanley J. Wrobel , Hong J. Zhang , Edward J. Ellis
IPC分类号： C11D1/66 , C11D1/90 , C11D1/94 , C11D3/00 , C11D3/37 , B08B7/00 , C11D3/48 , C11D9/36
CPC分类号： C11D3/3738 , C11D1/94 , C11D3/0078 , C11D1/66 , C11D1/662 , C11D1/90 , Y10S514/839
摘要： Compositions for the care of contact lenses include a silicone polymer containing an alkyleneoxide side chain.
摘要翻译：用于护理隐形眼镜的组合物包括含有环氧烷侧链的硅氧烷聚合物。

10. 发明授权

US5888950A Alcohol-containing abrasive composition for cleaning contact lenses 失效
标题翻译：用于清洁隐形眼镜的含酒精磨料组合物
公开(公告)号：US5888950A
公开(公告)日：1999-03-30
申请号：US752423
申请日：1996-11-19
申请人： Chimpiramma Potini , Stanley J. Wrobel
发明人： Chimpiramma Potini , Stanley J. Wrobel
IPC分类号： C11D1/14 , C11D1/72 , C11D1/722 , C11D1/83 , C11D3/00 , C11D3/14 , C11D3/20
CPC分类号： C11D1/83 , C11D3/0078 , C11D3/14 , C11D3/201 , C11D1/008 , C11D1/14 , C11D1/72
摘要： An aqueous composition for cleaning contact lenses comprises an aliphatic monohydric alcohol, a surface active agent having cleaning action for contact lens deposits, and an abrasive agent.
摘要翻译：用于清洁隐形眼镜的水性组合物包括脂族一元醇，具有用于隐形眼镜沉积物的清洁作用的表面活性剂和研磨剂。

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