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1. 发明申请

US20100237013A1 AUTONOMOUS FILTER ELEMENT 审中-公开
标题翻译：自动过滤器元件
公开(公告)号：US20100237013A1
公开(公告)日：2010-09-23
申请号：US12699996
申请日：2010-02-04
申请人： Aaron Burke , Anthony DiLeo , Timothy O'Brien
发明人： Aaron Burke , Anthony DiLeo , Timothy O'Brien
IPC分类号： B01D61/22 , B01D35/18 , B01D35/14 , B01D35/143
CPC分类号： B01D53/22 , B01D61/22 , B01D63/08 , B01D65/02 , B01D65/08 , B01D2311/103 , B01D2311/16 , B01D2313/22 , B01D2321/40 , G01F1/6888 , G01F1/69 , G01F15/125
摘要： An autonomous filter device and a method for improving the filter life and performance is disclosed. The filter element is equipped with one or more sensors, adapted to measure one or more characteristics or parameters of the fluid, such as temperature, pressure, or flow rate. In response to the measured characteristic or parameter, the control logic within the filter element is able to determine an appropriate response. For example, the control logic may determine that a sudden, but temporary, blockage has occurred in the filter membrane. In response to this, the control logic may initiate a specific response designed to alleviate the blockage. This response may be a temperature change, a vibration, a change in fluid flow path, or some other action. The control logic will then determine the success of the response, based monitoring any change in the fluid characteristics. Based thereon, the control logic may alert the operator that the filter element must be replaced. Alternatively, if the response was successful in correcting the blockage, the control logic need not notify the operator, as the filter element is back to normal operating operation.
摘要翻译：公开了一种自主的过滤装置和用于提高过滤器寿命和性能的方法。过滤元件配备有一个或多个传感器，适于测量流体的一个或多个特性或参数，例如温度，压力或流速。响应于测量的特性或参数，滤波器元件内的控制逻辑能够确定适当的响应。例如，控制逻辑可以确定在过滤膜中已经发生突然而暂时的堵塞。响应于此，控制逻辑可以发起旨在减轻阻塞的特定响应。该响应可能是温度变化，振动，流体流动路径的变化或某些其他动作。然后，控制逻辑将确定响应的成功，基于监测流体特性的任何变化。基于此，控制逻辑可以警告操作者必须更换过滤元件。或者，如果响应成功地纠正堵塞，则控制逻辑不需要通知操作者，因为过滤器元件已经回到正常的操作操作。

2. 发明申请

US20130008838A1 Autonomous Filter Element 审中-公开
公开(公告)号：US20130008838A1
公开(公告)日：2013-01-10
申请号：US13584023
申请日：2012-08-13
申请人： Aaron Burke , Anthony DiLeo , Timothy O'Brien
发明人： Aaron Burke , Anthony DiLeo , Timothy O'Brien
IPC分类号： B01D35/14
CPC分类号： B01D53/22 , B01D61/22 , B01D63/08 , B01D65/02 , B01D65/08 , B01D2311/103 , B01D2311/16 , B01D2313/22 , B01D2321/40 , G01F1/6888 , G01F1/69 , G01F15/125
摘要： An autonomous filter device and a method for improving the filter life and performance is disclosed. The filter element is equipped with one or more sensors, adapted to measure one or more characteristics. In response to the measured characteristic, the control logic within the filter element is able to determine an appropriate response. For example, the control logic may determine that a sudden, but temporary, blockage has occurred in the filter membrane. In response, the control logic may initiate a specific response designed to alleviate the blockage. The control logic will then determine the success of the response, based monitoring any change in the fluid characteristics. Based thereon, the control logic may alert the operator that the filter element must be replaced. Alternatively, if the response was successful in correcting the blockage, the control logic need not notify the operator, as the filter element is back to normal operating operation.

3. 发明申请

US20120318738A1 Autonomous Filter Element 审中-公开
标题翻译：自动过滤元件
公开(公告)号：US20120318738A1
公开(公告)日：2012-12-20
申请号：US13584032
申请日：2012-08-13
申请人： Aaron Burke , Anthony DiLeo , Timothy O'Brien
发明人： Aaron Burke , Anthony DiLeo , Timothy O'Brien
IPC分类号： B01D65/08 , B01D35/18 , G08B21/00 , B01D35/14
CPC分类号： B01D53/22 , B01D61/22 , B01D63/08 , B01D65/02 , B01D65/08 , B01D2311/103 , B01D2311/16 , B01D2313/22 , B01D2321/40 , G01F1/6888 , G01F1/69 , G01F15/125
摘要： An autonomous filter device and a method for improving the filter life and performance is disclosed. The filter element is equipped with one or more sensors, adapted to measure one or more characteristics. In response to the measured characteristic, the control logic within the filter element is able to determine an appropriate response. For example, the control logic may determine that a sudden, but temporary, blockage has occurred in the filter membrane. In response, the control logic may initiate a specific response designed to alleviate the blockage. The control logic will then determine the success of the response, based monitoring any change in the fluid characteristics. Based thereon, the control logic may alert the operator that the filter element must be replaced. Alternatively, if the response was successful in correcting the blockage, the control logic need not notify the operator, as the filter element is back to normal operating operation.
摘要翻译：公开了一种自主的过滤装置和改善过滤器寿命和性能的方法。过滤器元件配备有适于测量一个或多个特性的一个或多个传感器。响应于测量的特性，滤波器元件内的控制逻辑能够确定适当的响应。例如，控制逻辑可以确定在过滤膜中已经发生突然而暂时的堵塞。作为响应，控制逻辑可以启动旨在减轻阻塞的特定响应。然后，控制逻辑将确定响应的成功，基于监测流体特性的任何变化。基于此，控制逻辑可以警告操作者必须更换过滤元件。或者，如果响应成功地纠正堵塞，则控制逻辑不需要通知操作者，因为过滤器元件已经回到正常的操作操作。

4. 发明申请

US20100201521A1 SAMPLING SYSTEM 有权
标题翻译：采样系统
公开(公告)号：US20100201521A1
公开(公告)日：2010-08-12
申请号：US12452747
申请日：2008-07-18
申请人： George Adams , John Dana Hubbard , Aaron Burke , Anthony DiLeo
发明人： George Adams , John Dana Hubbard , Aaron Burke , Anthony DiLeo
IPC分类号： G08B13/14
CPC分类号： G01N35/00732 , B01L3/505 , B01L3/545 , B01L2300/022 , C12M33/00 , C12M33/06 , C12M37/00 , G01N1/18 , G01N2001/1031 , G01N2001/205 , G01N2035/00782 , G01N2035/00801
摘要： The present invention uses a wireless memory/communication device at least on the one or more sample storage devices, preferably on both the one or more sample storage devices and the sampling holder, optionally the port on the equipment as well. Data such as that relating to the vessel, the location of the port on the vessel, the device, its manufacture date or lot number, the date of the installation, sterilization and/or taking of a sample along with the person who installed the device and/or took the sample can be read and preferably added to the wireless device when a read/write type of device as these events occur through a scanner/reader/writer device (fixed or hand held). The sample storage device in the laboratory can also then be read and recorded to track the sample storage device's life.
摘要翻译：本发明至少在至少一个或多个样本存储设备上使用无线存储器/通信设备，优选地在一个或多个采样存储设备和采样保持器两者上，可选地，设备上的端口也使用无线存储器/通信设备。与船舶有关的数据，船上港口的位置，设备，其制造日期或批号，安装日期，灭菌和/或采样样品以及安装设备的人员当通过扫描仪/读写器装置（固定或手持）发生这些事件的读/写类型的装置时，可以读取样本并且优选地添加到无线装置。实验室中的样品存储设备也可以被读取和记录，以跟踪样品存储设备的使用寿命。

5. 发明授权

US08957778B2 Sampling system 有权
标题翻译：抽样系统
公开(公告)号：US08957778B2
公开(公告)日：2015-02-17
申请号：US12452747
申请日：2008-07-18
申请人： George Adams , John Dana Hubbard , Aaron Burke , Anthony DiLeo
发明人： George Adams , John Dana Hubbard , Aaron Burke , Anthony DiLeo
IPC分类号： A61J1/00 , G01N1/18 , C12M1/26 , B01L3/00 , G01N1/10 , G01N1/20 , G01N35/00
CPC分类号： G01N35/00732 , B01L3/505 , B01L3/545 , B01L2300/022 , C12M33/00 , C12M33/06 , C12M37/00 , G01N1/18 , G01N2001/1031 , G01N2001/205 , G01N2035/00782 , G01N2035/00801
摘要： The present invention uses a wireless memory/communication device at least on the one or more sample storage devices, preferably on both the one or more sample storage devices and the sampling holder, optionally the port on the equipment as well. Data such as that relating to the vessel, the location of the port on the vessel, the device, its manufacture date or lot number, the date of the installation, sterilization and/or taking of a sample along with the person who installed the device and/or took the sample can be read and preferably added to the wireless device when a read/write type of device as these events occur through a scanner/reader/writer device (fixed or hand held). The sample storage device in the laboratory can also then be read and recorded to track the sample storage device's life.
摘要翻译：本发明至少在至少一个或多个样本存储设备上使用无线存储器/通信设备，优选地在一个或多个采样存储设备和采样保持器两者上，可选地，设备上的端口也使用无线存储器/通信设备。与船舶有关的数据，船上港口的位置，设备，其制造日期或批号，安装日期，灭菌和/或采样样品以及安装设备的人员当通过扫描仪/读写器装置（固定或手持）发生这些事件的读/写类型的装置时，可以读取样本并且优选地添加到无线装置。实验室中的样品存储设备也可以被读取和记录，以跟踪样品存储设备的使用寿命。

6. 发明授权

US08955340B2 Biocontainer with integrated temperature sensor 有权
标题翻译：具有集成温度传感器的生物容器
公开(公告)号：US08955340B2
公开(公告)日：2015-02-17
申请号：US12685952
申请日：2010-01-12
申请人： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
发明人： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
IPC分类号： F25D25/00 , B65B63/08 , F25D3/08 , F25D29/00 , A01N1/02
CPC分类号： F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
摘要： The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
摘要翻译：本发明的生物容器提供了在生物药物材料的运输，冷冻和解冻期间遇到的许多问题的低成本，简单的解决方案。本发明使得用户能够在低温过程期间监测每个生物药物容器的温度曲线，以便通过使用预先安装和预灭菌的温度传感器来确保每个生物容器内的材料的完整性。在一些实施例中，传感器组件包括无线发射器，并且能够发送关于测量读数的信息。在其他实施例中，传感器组件包括处理单元，其确定温度分布是否可接受。在另一实施例中，包括指示器，使得处理单元可以指示生物药物材料是否已被适当地冷冻。在其他实施例中，传感器组件还包括存储元件，其能够在冷冻过程期间存储各种参数。

7. 发明授权

US08497775B2 Use of gamma hardened RFID tags in pharmaceutical devices 有权
标题翻译：在制药设备中使用伽马硬化的RFID标签
公开(公告)号：US08497775B2
公开(公告)日：2013-07-30
申请号：US13301871
申请日：2011-11-22
申请人： Aaron Burke
发明人： Aaron Burke
IPC分类号： G08B13/14 , H01L21/00 , H01L29/82 , A61L2/00
CPC分类号： G11C11/22 , A61L2/081 , A61L2202/24 , B65B55/16 , G06K19/077 , G06K19/07749 , G11C11/16
摘要： A system and method for utilizing RFID tags in environments where radiation is used is disclosed. RFID tags are secured to various components of a pharmaceutical system, thereby enabling the customer to download pertinent information about the component, such as lot number, date of manufacturer, test parameters, etc. The tags can be applied to the component immediately after manufacture and can be subjected to the sterilization process without risk of data loss or corruption. The memory device within the tag utilizes a technology that does not rely upon charge storage as its mechanism to store information.
摘要翻译：公开了在使用辐射的环境中利用RFID标签的系统和方法。 RFID标签被固定到药物系统的各种组件，从而使客户能够下载关于组件的相关信息，例如批号，制造商的日期，测试参数等。标签可以在制造后立即应用于部件，可以进行灭菌过程，而不会有数据丢失或损坏的风险。标签内的存储设备利用不依赖于电荷存储作为其存储信息的机制的技术。

8. 发明授权

US08405508B2 Use of gamma hardened RFID tags in pharmaceutical devices 有权
标题翻译：在制药设备中使用伽马硬化的RFID标签
公开(公告)号：US08405508B2
公开(公告)日：2013-03-26
申请号：US11501446
申请日：2006-08-09
申请人： Aaron Burke
发明人： Aaron Burke
IPC分类号： G08B13/14 , H01L21/00 , H01L29/82 , A61L2/00
CPC分类号： G11C11/22 , A61L2/081 , A61L2202/24 , B65B55/16 , G06K19/077 , G06K19/07749 , G11C11/16
摘要： A system and method for utilizing RFID tags in environments where radiation is used is disclosed. RFID tags are secured to various components of a pharmaceutical system, thereby enabling the customer to download pertinent information about the component, such as lot number, date of manufacturer, test parameters, etc. The tags can be applied to the component during or immediately after manufacture and can be subjected to the sterilization process without risk of data loss or corruption. The memory device within the tag utilizes a technology that does not rely upon charge storage as its mechanism to store information.
摘要翻译：公开了在使用辐射的环境中利用RFID标签的系统和方法。 RFID标签被固定在药物系统的各种组件上，从而使客户能够下载关于组件的相关信息，例如批号，制造商日期，测试参数等。标签可以在或之后被应用于组件制造并可以进行灭菌过程，而不会有数据丢失或损坏的风险。标签内的存储设备利用不依赖于电荷存储作为其存储信息的机制的技术。

9. 发明授权

US07969380B2 Antenna gasket for process housings 有权
标题翻译：工艺外壳天线垫圈
公开(公告)号：US07969380B2
公开(公告)日：2011-06-28
申请号：US13020914
申请日：2011-02-04
申请人： Aaron Burke , Michael Joens
发明人： Aaron Burke , Michael Joens
IPC分类号： H01Q1/42
CPC分类号： H01Q9/16 , B01D29/52 , B01D46/4245 , B01D46/429 , B01D2201/34 , B01D2201/56 , B01D2271/02 , H01Q1/22 , H01Q1/2216 , H01Q1/40 , H01Q1/50
摘要： A method and apparatus for providing wireless communication and optionally power to the interior of a housing assembly is disclosed. In one embodiment, an antenna is molded within a gasket material, such as silicon, so as to be completely encapsulated. The gasket preferably includes at least one support arm, which holds the antenna toward the middle of the housing, so as to minimize interference from the metal housing. In further embodiments, an inductive coil is encapsulated in the gasket. An alternating current is passed through this coil to create a changing magnetic field, which can then be used to create electrical power in physically separate components, such as filtering elements. In certain embodiments, multiple loops are molded to correspond to multiple filtering elements within the housing.
摘要翻译：公开了一种用于向壳体组件的内部提供无线通信和可选地供电的方法和装置。在一个实施例中，将天线模制在衬垫材料（例如硅）内，以便被完全封装。垫片优选地包括至少一个支撑臂，其将天线朝向壳体的中间保持，以便最小化来自金属壳体的干扰。在另外的实施例中，感应线圈封装在垫圈中。交流电流通过该线圈以产生变化的磁场，其然后可用于在物理上分离的部件（例如过滤元件）中产生电力。在某些实施例中，模制多个环以对应于壳体内的多个过滤元件。

10. 发明授权

US07892471B2 Wireless enabled device 有权
标题翻译：无线使能设备
公开(公告)号：US07892471B2
公开(公告)日：2011-02-22
申请号：US11985471
申请日：2007-11-15
申请人： Aaron Burke , Joseph William Muldoon
发明人： Aaron Burke , Joseph William Muldoon
IPC分类号： B29C65/02
CPC分类号： B29C66/474 , B29C65/02 , B29C65/06 , B29C65/08 , B29C65/14 , B29C66/112 , B29C66/1122 , B29C66/114 , B29C66/24244 , B29C66/30221 , B29C66/30223 , B29C66/47 , B29C66/472 , B29C66/53461 , B29C66/61 , B29C66/71 , B29C70/70 , B29C70/74 , G06K19/07758 , Y10T403/28 , Y10T428/1352 , B29K2023/00 , B29K2023/06 , B29K2023/083 , B29K2023/12 , B29K2027/06 , B29K2027/12 , B29K2027/16 , B29K2033/20 , B29K2055/02 , B29K2067/00 , B29K2069/00 , B29K2077/00 , B29K2081/06
摘要： The invention described herein provides an embedded wireless device such as a RFID tag molded into separate housing formed of any thermoplastic material compatible to that of the plastic material as the device to which the housing is to be attached. Subsequently, the housed tag assembly can be thermally bonded onto the device through many means which are well known and accepted in the industry.
摘要翻译：本文描述的本发明提供了一种嵌入式无线设备，例如模制成分离的壳体的RFID标签，其由与塑料材料相兼容的任何热塑性材料形成，作为与壳体相连接的装置。随后，容纳的标签组件可以通过工业上众所周知和被接受的许多方式热粘合到设备上。

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