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1. 发明申请

WO2006063182A3 ORTHOPIC RECONSTITUTED HUMAN BREAST TUMOR MODEL IN MOUSE 审中-公开
标题翻译：正常重建的人类乳腺肿瘤模型
公开(公告)号：WO2006063182A3
公开(公告)日：2007-01-18
申请号：PCT/US2005044508
申请日：2005-12-06
申请人： AVEO PHARMACEUTICALS INC , WU MIN , KUPERWASSER CHARLOTTE , ROBINSON MURRAY
发明人： WU MIN , KUPERWASSER CHARLOTTE , ROBINSON MURRAY
IPC分类号： C12N15/85 , A01K67/027 , C07K14/82 , C12N5/10 , G01N33/50
CPC分类号： A61K49/0008 , A01K67/0271 , A01K2227/105 , A01K2267/0331 , C12N2510/04 , C12N2799/027
摘要： Reconstituted human breast tumor models are disclosed. The models, which are incorporated into mice, provide actual tumors that arise spontaneously, thereby mimicking naturally occurring breast cancer. The tumors are genetically human, because they arise from human mammary tissues that develop from human mammary epithelial cells implanted into host mice. Prior to implantation, the mammary epithelial cells are genetically modified to contain either: (a) a recombinant human oncogene and an SV40er; or (b) a recombinant human oncogene, a transgene or shRNA that inhibits the p53 pathway, and a transgene or shRNA that inhibits the Rb pathway.
摘要翻译：公开了重建的人乳腺肿瘤模型。结合到小鼠中的模型提供自发产生的实际肿瘤，从而模仿天然存在的乳腺癌。这些肿瘤是遗传性的，因为它们来源于植入宿主小鼠的人类乳腺上皮细胞发育的人类乳腺组织。在植入之前，乳腺上皮细胞被遗传修饰以包含：（a）重组人癌基因和SV40er; 或（b）重组人癌基因，抑制p53途径的转基因或shRNA，以及抑制Rb途径的转基因或shRNA。

2. 发明专利

AU2005314003B8 Reconstituted human breast tumor model 未知
公开(公告)号：AU2005314003B8
公开(公告)日：2011-04-21
申请号：AU2005314003
申请日：2005-12-06
申请人： AVEO PHARMACEUTICALS INC
发明人： ROBINSON MURRAY , WU MIN , KUPERWASSER CHARLOTTE
IPC分类号： C12N15/85 , A01K67/027 , C07K14/82 , C12N5/10 , G01N33/50

3. 发明专利

AU2005314003B2 Orthopic reconstituted human breast tumor model in mouse 未知
公开(公告)号：AU2005314003B2
公开(公告)日：2011-04-07
申请号：AU2005314003
申请日：2005-12-06
申请人： AVEO PHARMACEUTICALS INC
发明人： ROBINSON MURRAY , WU MIN , KUPERWASSER CHARLOTTE
IPC分类号： C12N15/85 , A01K67/027 , C07K14/82 , C12N5/10 , G01N33/50

4. 发明专利

AU2005314003A1 Orthopic reconstituted human breast tumor model in mouse 未知
公开(公告)号：AU2005314003A1
公开(公告)日：2006-06-15
申请号：AU2005314003
申请日：2005-12-06
申请人： AVEO PHARMACEUTICALS INC
发明人： ROBINSON MURRAY , WU MIN , KUPERWASSER CHARLOTTE
IPC分类号： C12N15/85 , A01K67/027 , C07K14/82 , C12N5/10 , G01N33/50

5. 发明申请

WO2007115315A2 PYRROLO- AND THIAZOLO-PYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF 审中-公开
标题翻译：吡咯并 - 噻唑并吡啶化合物及其使用方法
公开(公告)号：WO2007115315A2
公开(公告)日：2007-10-11
申请号：PCT/US2007065987
申请日：2007-04-04
申请人： FIBROGEN INC , DENG SHAOJIANG , WU MIN , TURTLE ERIC D , HO WEN-BIN , AREND MICHAEL P , CHENG HENG , FLIPPIN LEE A
发明人： DENG SHAOJIANG , WU MIN , TURTLE ERIC D , HO WEN-BIN , AREND MICHAEL P , CHENG HENG , FLIPPIN LEE A
CPC分类号： C07D471/04 , C07D513/04
摘要： The present invention relates to novel compounds capable of modulating the stability and/or activity of hypoxia inducible factor (HIF).
摘要翻译：本发明涉及能够调节缺氧诱导因子（HIF）的稳定性和/或活性的新型化合物。

6. 发明申请

WO2007127047A2 CONTOUR TRIANGULATION SYSTEM AND METHOD 审中-公开
标题翻译：轮廓三角形系统和方法
公开(公告)号：WO2007127047A2
公开(公告)日：2007-11-08
申请号：PCT/US2007008810
申请日：2007-04-11
申请人： MAKO SURGICAL CORP , ARATA LOUIS K , WU MIN
发明人： ARATA LOUIS K , WU MIN
IPC分类号： G06T17/20
CPC分类号： G06T17/20
摘要： A method and apparatus for reconstructing a surface shape of an object having contour lines, includes assigning points to each contour line. A first triangulation scheme is performed with respect to respective points on two adjacently-positioned contour lines, to determine a first surface shape for a portion of the object corresponding to the two contour lines. The first surface shape is checked to determine if the first surface shape is in error. If the first surface shape is not in error, the first surface shape is outputted for the portion of the object as determined by the first triangulation scheme, as a reconstructed surface shape for that portion of the object. If the first surface shape is in error, a second triangulation scheme is performed with respect to the respective points on the two contour lines, to determine a second surface shape for that portion of the object, and the second surface shape is outputted for that portion of the object as determined by the second triangulation scheme, as a reconstructed surface shape.
摘要翻译：一种用于重建具有轮廓线的物体的表面形状的方法和设备，包括将点分配给每个轮廓线。针对两条相邻定位的轮廓线上的各个点执行第一三角测量方案，以确定对应于两条轮廓线的物体的一部分的第一表面形状。检查第一个表面形状以确定第一个表面形状是否有误。如果第一表面形状没有错误，则将由第一三角测量方案确定的对象部分的第一表面形状输出为该对象部分的重建表面形状。如果第一表面形状出错，则关于两条轮廓线上的各个点执行第二三角测量方案，以确定物体的该部分的第二表面形状，并且针对该部分输出第二表面形状由第二三角测量方案确定的物体的重建表面形状。

7. 发明申请

WO2009120913A3 REUSE ENGINE WITH TASK LIST FOR FAST FOURIER TRANSFORM AND METHOD OF USING THE SAME 审中-公开
标题翻译：用快速傅里叶变换的任务列表重新使用发动机及其使用方法
公开(公告)号：WO2009120913A3
公开(公告)日：2011-01-13
申请号：PCT/US2009038473
申请日：2009-03-27
申请人： QUALCOMM INC , CHAUDHURI ARUNAVA , SAMPATH HEMANTH , YAO IWEN , LIN JEREMY H , CHALLA RAGHU N , WU MIN
发明人： CHAUDHURI ARUNAVA , SAMPATH HEMANTH , YAO IWEN , LIN JEREMY H , CHALLA RAGHU N , WU MIN
IPC分类号： G06F17/14
CPC分类号： G06F17/142 , H04L5/0007 , H04L5/0023 , H04L5/0053 , H04L27/265 , H04L27/2662
摘要： An improved processing engine for performing Fourier transforms includes an instruction processor configured to process sequential instruction software commands and a Fourier transform engine coupled to the instruction processor. The Fourier transform engine is configured to perform Fourier transforms on a serial stream of data. The Fourier transform engine is configured to receive configuration information and operational data from the instruction processor via a set of software tasks.
摘要翻译：用于执行傅里叶变换的改进的处理引擎包括配置成处理顺序指令软件命令的指令处理器和耦合到指令处理器的傅里叶变换引擎。傅立叶变换引擎被配置为对串行数据流执行傅里叶变换。傅里叶变换引擎被配置为经由一组软件任务从指令处理器接收配置信息和操作数据。

8. 发明申请

WO2005018573A3 6-CYCLOAMINO-2-QUINOLINONE DERIVATIVES AS ANDROGEN RECEPTOR MODULATOR COMPOUNDS 审中-公开
标题翻译：作为雄激素受体调节剂化合物的6-环脒基-2-喹啉酮衍生物
公开(公告)号：WO2005018573A3
公开(公告)日：2005-05-06
申请号：PCT/US2004027483
申请日：2004-08-23
申请人： LIGAND PHARM INC , ZHI LIN , MARTINBOROUGH ESTHER , SHEN YIXING , STEVENS LAU THOMAS LOT , WU MIN , LONG YUN OLIVER
发明人： ZHI LIN , MARTINBOROUGH ESTHER , SHEN YIXING , STEVENS LAU THOMAS LOT , WU MIN , LONG YUN OLIVER
IPC分类号： A61K20060101 , A61K31/47 , C07D215/12 , C07D215/16
CPC分类号： C07D401/04
摘要： The present invention is directed to compounds, pharmaceutical compositions, and methods for modulating processes mediated by AR. Also provided are methods of making such compounds and pharmaceutical compositions.
摘要翻译：本发明涉及用于调节由AR介导的过程的化合物，药物组合物和方法。还提供了制备这种化合物和药物组合物的方法。

9. 发明申请

WO0233650A8 HUMAN VISUAL MODEL FOR DATA HIDING 审中-公开
标题翻译：人类视觉模型用于数据隐藏
公开(公告)号：WO0233650A8
公开(公告)日：2002-09-12
申请号：PCT/US0132247
申请日：2001-10-17
申请人： MATSUSHITA ELECTRIC IND CO LTD , WU MIN , YU HONG HEATHER
发明人： WU MIN , YU HONG HEATHER
IPC分类号： G06T1/00 , H04N1/387 , G06K9/00 , G06K9/36
CPC分类号： G06T1/0092 , G06T1/0028 , G06T2201/0051 , G06T2201/0052 , G06T2201/0061 , G06T2201/0202
摘要： A method and apparatus of hiding identification data (12) in visual media. When image or video data is received, frequency masking (14) is performed to divide the image or video data into blocks of smooth regions and blocks of non-smooth regions and to obtain preliminary just-noticeable-difference. Edge detection is performed to divide the non-smooth region of the image or video data into texture blocks and edge blocks (16). The image or video data is then adjusted by applying different strength of watermark in association with the type of each block.
摘要翻译：一种在视觉媒体中隐藏识别数据（12）的方法和装置。当接收到图像或视频数据时，执行频率屏蔽（14）以将图像或视频数据划分为平滑区域和非平滑区域块，并获得初步的明显差异。执行边缘检测以将图像或视频数据的非平滑区域划分为纹理块和边缘块（16）。然后通过与每个块的类型相关联地应用不同强度的水印来调整图像或视频数据。

10. 发明申请

WO2009085037A2 CUMULATIVE BUFFERING FOR SURFACE IMAGING 审中-公开
标题翻译：表面成像的累积缓冲
公开(公告)号：WO2009085037A2
公开(公告)日：2009-07-09
申请号：PCT/US2007088702
申请日：2007-12-21
申请人： MAKO SURGICAL CORP , WU MIN
发明人： WU MIN
IPC分类号： G06T7/40 , G06F19/00
CPC分类号： G06F19/3481 , A61B34/20 , A61B34/25 , A61B34/30 , A61B90/92 , A61B2034/102 , A61B2034/252 , G06T17/10 , G06T19/00 , G06T2210/41 , G16H50/50
摘要： The description relates to surgical computer systems, including computer program products, and methods for cumulative buffering for surface imaging. A display image is buffered that has been saved from a previous update. A model representing a tool is subtracted from the buffered display image. The subtracted display image is displayed using a CSG technique at a fixed angle. The subtracted display image is saved. This process is repeated so that the displayed image is cumulatively changed with each change in location of the model representing the tool.
摘要翻译：描述涉及外科计算机系统，包括计算机程序产品，以及用于表面成像的累积缓冲的方法。缓存的显示图像已从先前的更新中保存。从缓冲的显示图像中减去表示工具的模型。使用CSG技术以固定的角度显示相减的显示图像。减去的显示图像被保存。重复该过程，使得显示的图像随着表示工具的模型的位置的每次改变而累积地改变。

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